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Hemogram-derived ratios as prognostic markers for major adverse cardiovascular events in patients with non-ST-segment elevation myocardial infarction

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World Journal of Methodology 2025年第2期15卷 125-136页

作者： Emir Bećirović Minela Bećirović SabinaŠegalo Amir Bećirović Semir Hadžić Kenana Ljuca Emsel Papić Lamija Ferhatbegović Malik Ejubović Amira JagodićEjubović Amila Kovčić ArminŠljivo Emir Begagić Department of intensive Care University Clinical Center TuzlaTuzla 75000Bosnia and Herzegovina Department of Nephrology University Clinical Center TuzlaTuzla 75000Bosnia and Herzegovina Department of Laboratory Technologies Faculty of Health SciencesUniversity of SarajevoSarajevo 71000Bosnia and Herzegovina Department of Endocrinology University Clinical Center TuzlaTuzla 75000Bosnia and Herzegovina School of Medicine University of TuzlaTuzla 75000Bosnia and Herzegovina Department for internal Diseases and Hemodialysis Canton Hospital ZenicaZenica 72000Bosnia and Herzegovina Department of internal Medicine Canton Hospital ZenicaZenica 72000Bosnia and Herzegovina Department of Radiotherapy University Clinical Center TuzlaTuzla 75000Bosnia and Herzegovina Department of Cardiology University Clinical Center SarajevoSarajevo 72000Bosnia and Herzegovina Department of General Medicine University of ZenicaSchool of MedicineZenica 72000Bosnia and Herzegovina

BACKGROUND Non-ST segment elevation myocardial infarction(NSTEMi)poses significant challenges in clinical management due to its diverse *** the prognostic role of hematological parameters and derived ratios in NSTEMi patients could aid in risk stratification and improve patient *** To evaluate the predictive value of hemogram-derived ratios for major adverse cardiovascular events(MACE)in NSTEMi patients,potentially improving clinical *** A prospective,observational cohort study was conducted in 2021 at the internal Medicine Clinic of the University Hospital in Tuzla,Bosnia and *** study included 170 patients with NSTEMi,who were divided into a group with MACE and a control group without ***,the MACE group was subdivided into lethal and non-lethal groups for prognostic *** hematological parameters,an additional 13 hematological-derived ratios(HDRs)were monitored,and their prognostic role was *** Hematological parameters did not significantly differ between non-ST segment elevation myocardial infarction(NSTEMi)patients with MACE and a control group at T1 and ***,significant disparities emerged in HDRs among NSTEMi patients with lethal and non-lethal outcomes ***,neutrophil-to-lymphocyte ratio(NLR)and platelet-to-lymphocyte ratio(PLR)were elevated in lethal ***,C-reactive protein-to-lymphocyte ratio(CRP/Ly)at T1(>4.737)demonstrated predictive value[odds ratio(OR):3.690,P=0.024].Both NLR at T1(>4.076)and T2(>4.667)emerged as significant predictors,with NLR at T2 exhibiting the highest diagnostic performance,as indicated by an area under the curve of 0.811(95%Ci:0.727-0.859)and OR of 4.915(95%Ci:1.917-12.602,P=0.001),emphasizing its important role as a prognostic *** This study highlights the significant prognostic value of hemogram-derived indexes in predicting MACE among NSTEMi *** follow-up,NLR,PLR,and CRP/Ly off

关键词： Hemogram-derived ratios Prognostic markers Neutrophil-to-lymphocyte ratio Myocardial infarction

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Post-transplant lymphoproliferative disorder after liver transplantation: incidence, long-term survival and impact of serum tacrolimus level

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World Journal of Gastroenterology 2017年第7期23卷 1224-1232页

作者： Ahad Eshraghian Mohammad Hadi.imanieh Seyed Mohsen Dehghani Saman Nikeghbalian Alireza Shamsaeefar Frouzan Barshans Kourosh Kazemi Bita Geramizadeh Seyed Ali Malek-Hosseini Transplant Research Center Shiraz University of Medical Sciences Gastroenterohepatology Research Center Namazi Hospital

To investigate incidence and survival of post-transplant lymphoproliferative disorder (PTLD) patients after liver *** cross-sectional survey was conducted among patients who underwent liver transplantation at Shiraz Transplant Center (Shiraz, iran) between August 2004 and March 2015. Clinical and laboratory data of patients were collected using a data gathering *** were 40 cases of PTLD in the pediatric age group and 13 cases in the adult group. The incidence of PTLD was 6.25% in pediatric patients and 1.18% in adult liver transplant recipients. The post-PTLD survival of patients at 6 mo was 75.1% ± 6%, at 1 year was 68.9% ± 6.5% and at 5 years was 39.2% ± 14.2%. Higher serum tacrolimus level was associated with lower post-PTLD survival in pediatric patients (OR = 1.07, 95%Ci: 1.006-1.15, P = 0.032). A serum tacrolimus level over 11.1 ng/mL was predictive of post PTLD survival (sensitivity = 90%, specificity = 52%, area under the curve = 0.738, P = 0.035).CONCLUSiONincidence of PTLD in our liver transplant patients is comparable to other centers. Transplant physicians may consider adjustment of tacrolimus dose to maintain its serum level below this cutoff point.

关键词： Post-transplant lymphoproliferative disorder Liver transplantation Survival Tacrolimus Epstein-Barr virus

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TRiPHENYLPHOSPHiNE PROMOTED ADDiTiON OF DiALKYL ACETYLENEDiCARBOXYLATES TO PHETHALiC ANHYDRiDE DERiVATiVES:FACiLE SYNTHESiS OF Γ-SPiROLACTONES

TRIPHENYLPHOSPHINE PROMOTED ADDITION OF DIALKYL ACETYLENEDIC...

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40th iUPAC Congress

作者： Mohammad Bayat issa Yavari Hossien imanieh Hossien Farjam Department of Chemistry Imam Khomeini International UniversityP. O. Box 288QazvinIran Department of Chemistry Tarbiat Modarres UniversityP. O. Box 14115-175TehranIran Department of Chemistry Imam Khomeini International UniversityP. O. Box 288QazvinIran Department of Chemistry Imam Khomeini International UniversityP. O. Box 288QazvinIran

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One-range addition theorems for generalized integer and noninteger μ Coulomb,and exponential type correlated interaction potentials with hyperbolic cosine in position,momentum,and four-dimensional spaces

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Chinese Physics B 2012年第6期21卷 137-140页

作者： i.i.Guseinov Department of Physics Faculty of Arts and SciencesOnsekiz Mart UniversityCanakkaleTurkey

The formulae are established in position,momentum,and four-dimensional spaces for the one-range addition theorems of generalized integer and noninteger μ Coulomb,and exponential type correlated interaction potentials with hyperbolic cosine（GCTCP and GETCP HC）.These formulae are expressed in terms of one-range addition theorems of complete orthonormal sets of Ψα-exponential type orbitals（Ψ α-ETO）,α-momentum space orbitals（α-MSO）,and zα-hyperspherical harmonics（zα-HSH） *** one-range addition theorems obtained can be useful in the electronic structure calculations of atoms and molecules when the GCTCP and GETCP HC in position,momentum,and four-dimensional spaces are employed.

关键词： correlated interaction potentials one-range additional theorems complete orthonormalsets of orbitals overlap integrals

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Size-dependent thermal stresses in the core–shell nanoparticles

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Chinese Physics B 2013年第12期22卷 483-490页

作者： Astefanoaei i Dumitru i Stancu Al Faculty of Physics "Alexandru Ioan Cuza" University of Iasi

The thermal stress in a magnetic core–shell nanoparticle during a thermal process is an important parameter to be known and controlled in the magnetization process of the core–shell system. in this paper we analyze the stress that appears in a core–shell nanoparticle subjected to a cooling process. The external surface temperature of the system, considered in equilibrium at room temperature, is instantly reduced to a target temperature. The thermal evolution of the system in time and the induced stress are studied using an analytical model based on a time-dependent heat conduction equation and a differential displacement equation in the formalism of elastic displacements. The source of internal stress is the difference in contraction between core and shell materials due to the temperature change. The thermal stress decreases in time and is minimized when the system reaches the thermal equilibrium. The radial and azimuthal stress components depend on system geometry, material properties, and initial and final temperatures. The magnitude of the stress changes the magnetic state of the core–shell system. For some materials, the values of the thermal stresses are larger than their specific elastic limits and the materials begin to deform plastically in the cooling process. The presence of the induced anisotropy due to the plastic deformation modifies the magnetic domain structure and the magnetic behavior of the system.

关键词： thermal stresses thermal equilibrium core–shell particle

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Unified treatment of one-range addition theorems for integer and non-integer n-STO, -GTO and -generalized exponential type orbitals with hyperbolic cosine in position, momentum and four-dimensional spaces

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Chinese Physics B 2012年第9期21卷 176-178页

作者： i. i. Guseinov Department of Physics Faculty of Arts and Sciences Onsekiz Mart University

Simpler formulas are derived for one-range addition theorems for the integer and noninteger n generalized ex- ponential type orbitals, momentum space orbitals, and hyperspherical harmonics with hyperbolic cosine （GETO HC, GMSO HC, and GHSH HC） in position, momentum and four-dimensional spaces, respectively. The final results are expressed in terms of one-range addition theorems of complete orthonormal sets of Ca-exponential type orbitals, Ca- momentum space orbitals and za-hyperspherical harmonics. We notice that the one-range addition theorems for integer and noninteger n-Slater type orbitals and Gaussian type orbitals in position, momentum and four dimensional spaces are special cases of GETO HC, GMSO HC, and GHSH HC. The theorems presented can be useful in the accurate study of the electronic structure of atomic and molecular systems.

关键词： electronic structure generalized exponential type orbitals one-range addition theorems,Hartree-Fock-Roothaan equations

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One-Range Addition Theorems in Terms of ψ^α -ETOs for STOs and Coulomb-Yukawa Like Correlated interaction Potentials of integer and Noninteger indices

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Chinese Physics Letters 2008年第12期25卷 4240-4243页

作者： i. i. Guseinov Department of Physics Faculty of Arts and Sciences Onsekiz Mart University Canakkale Turkey

The expansion formulas in terms of complete orthonormal sets of ψ^α -exponential type orbitals are established for the Slater type orbitals and Coulomb-Yukawa-like correlated interaction potentials of integer and noninteger indices. These relations are used in obtaining their unsymmetrical and symmetrical one-range addition theorems. The final results are especially useful in the calculations of multicentre multielectron integrals occurring when Hartree-Fock-Roothaan and explicitly correlated methods are employed.

关键词： orthonormal set expansion formula

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The effect of forced oscillations on the kinetics of wave drift in an inhomogeneous plasma

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Plasma Science and Technology 2020年第12期22卷 8-19页

作者： V i EROFEEV institute of Automation&Electrometry of the Siberian Branch of the Russian Academy of Sciences 1 Koptyug Prosp.630090NovosibirskRussia Novosibirsk State University 2 Pirogova Str.NovosibirskRussia

The kinetics is analyzed of the drift of non-potential plasma waves in spatial positions and wavevectors due to plasma's spatial inhomogeneity. The analysis is based on highly informative kinetic scenarios of the drift of electromagnetic waves in a cold ionized plasma in the absence of a magnetic field(Erofeev 2015 Phys. Plasmas 22 092302) and the drift of long Langmuir waves in a cold magnetized plasma(Erofeev 2019 J. Plasma Phys. 85 905850104). it is shown that the traditional concept of the wave kinetic equation does not account for the effects of the forced plasma oscillations that are excited when the waves propagate in an inhomogeneous *** are highlighted that account for these oscillations in the kinetic equations of the abovementioned highly informative wave drift scenarios.

关键词： informativeness of plasma kinetic scenario the ensemble method asymptotic convergence of perturbation theories correlation analysis of plasma kinetics kinetic equation of wave drift in phase space

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Unified treatment for accurate and fast evaluation of the Fermi-Dirac functions

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Chinese Physics B 2010年第5期19卷 72-77页

作者： i.i.Guseinov B.A.Mamedov Department of Physics Faculty of Arts and SciencesOnsekiz Mart UniversityCanakkaleTurkey Department of Physics Faculty of Arts and SciencesGaziosmanpa sa UniversityTokatTurkey

A new analytical approach to the computation of the Fermi-Dirac （FD） functions is presented, which was suggested by previous experience with various algorithms. Using the binomial expansion theorem these functions are expressed through the binomial coefficients and familiar incomplete Gamma functions. This simplification and the use of the memory of the computer for the calculation of binomial coefficients may extend the limits to large arguments for users and result in speedier calculation, should such limits be required in practice. Some numerical results are presented for significant mapping examples and they are briefly discussed.

关键词： statistical semiconductors plasma physics nuclear physics

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The sexually dimorphic expression of glutamate transporters and their implication in pain after spinal cord injury

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Neural Regeneration Research 2025年第11期20卷 3317-3329页

作者： Jennifer M.Colón-Mercado Aranza i.Torrado-Tapias iris K.Salgado Jose M.Santiago Samuel E.Ocasio Rivera Dina P.Bracho-Rincon Luis H.Pagan Rivera Jorge D.Miranda Department of Physiology University of Puerto RicoMedical Sciences CampusSan JuanPRUSA National institutes of Health National Human Genome Research InstituteBethesdaMDUSA Universidad Central del Caribe School of MedicineBayamónPRUSA University of Puerto Rico Carolina CampusCarolinaPRUSA institute of Neurobiology San JuanPRUSA

in addition to the loss of motor function,~60% of patients develop pain after spinal cord *** cellular-molecular mechanisms are not well understood,but the data suggests that plasticity within the rostral,epicenter,and caudal penumbra of the injury site initiates a cellularmolecular interplay that acts as a rewiring mechanism leading to central neuropathic *** can lead to the formation of new connections triggering abnormal sensory *** excitatory glutamate transporters are responsible for the reuptake of extracellular glutamate which makes them a critical target to prevent neuronal hyperexcitability and *** previous studies showed a sexually dimorphic therapeutic window for spinal cord injury after treatment with the selective estrogen receptor modulator *** this study,we investigated the anti-allodynic effects of tamoxifen in male and female rats with spinal cord *** hypothesized that tamoxifen exerts anti-allodynic effects by increasing the expression of glutamate transporters,leading to reduced hyperexcitability of the secondary neuron or by decreasing aberrant *** and female rats received a moderate contusion to the thoracic spinal cord followed by subcutaneous slow-release treatment of tamoxifen or matrix pellets as a control(placebo).We used von Frey monofilaments and the“up-down method”to evaluate mechanical *** treatment decreased allodynia only in female rats with spinal cord injury revealing a sexdependent *** expression profile of glutamatergic transporters(excitatory amino acid transporter 1/glutamate aspartate transporter and excitatory amino acid transporter 2/glutamate transporter-1)revealed a sexual dimorphism in the rostral,epicenter,and caudal areas of the spinal cord with a pattern of expression primarily on *** rodents showed a significantly higher level of excitatory amino acid transporter-1 expression while male rodents showed increased

关键词： allodynia central neuropathic pain EAAT-1/GLAST EAAT-2/GLT-1 glutamate transporters selective estrogen receptor modulator sexual dimorphism spinal cord injury trauma

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