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Energy & Environmental Materials 2024年第1期7卷 201-206页

作者： Gulsum Ersu Carmen Munuera Federico j.Mompean Daniel Vaquero jorge Quereda joão Elias F.S.rodrigues jose A.alonso Eduardo Flores jose r.Ares isabel j.Ferrer Abdullah M.Al-Enizi Ayman Nafady Sruthi Kuriakose joshua O.island Andres Castellanos-Gomez Materials Science Factory Instituto de Ciencia de Materiales de Madrid(ICMM-CSIC)Madrid E-28049Spain Nanotechnology Group USAL-NanolabUnivesidad de SalamancaSalamanca Junta de Castilla y León 37007Spain GiSC Departamento de Física de MaterialesUniversidad Complutense de MadridMadrid E-28040Spain Departamento de Física Aplicada Centro de Investigación y Estudios AvanzadosMérida 97310Mexico MirE Group Departamento de Física de MaterialesUniversidad Autónoma de MadridMadrid E-28049Spain instituto Nicolás Cabrera Universidad Autónoma de MadridMadrid E-28049Spain Department of Chemistry College of ScienceKing Saud UniversityRiyadh 11451Saudi Arabia Department of Physics and Astronomy University of Nevada Las VegasLas Vegas NV 89154USA

We present a method to fabricate handcrafted thermoelectric devices on standard office paper *** devices are based on thin films of WS_(2),Te,and BP(P-type semiconductors)and TiS_(3)and TiS_(2)(N-type semiconductors),deposited by simply rubbing powder of these materials against *** thermoelectric properties of these semiconducting films revealed maximum Seebeck coefficients of(+1.32±0.27)mV K^(-1)and(-0.82±0.15)mV K^(-1)for WS_(2)and TiS_(3),***,Peltier elements were fabricated by interconnecting the P-and N-type films with graphite electrodes.A thermopower value up to 6.11 mV K^(-1)was obtained when the Peltier element were constructed with three *** findings of this work show proof-of-concept devices to illustrate the potential application of semiconducting van der Waals materials in future thermoelectric power generation as well as temperature sensing for low-cost disposable electronic devices.

关键词： paper-based electronics Seebeck effect semiconductors thermoelectrics van der Waals materials

Engineering hyaluronic acid-based nanoassemblies for monoclonal antibody delivery-design,characterization,and biological insights

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Nano research 2024年第10期17卷 9111-9125页

作者： Ana M.López-Estévez Y.Zhang María Medel iker Arriaga Lucía Sanjurjo Cristian Huck-iriart Nicola G.A.Abrescia María j.Vicent Defang Ouyang Dolores Torres María josé alonso Center for research in Molecular Medicine and Chronic Diseases(CiMUS) University of Santiago de CompostelaSantiago de Compostela 15782Spain Department of Pharmacology Pharmacy and Pharmaceutical TechnologySchool of PharmacyUniversity of Santiago de CompostelaSantiago de Compostela 15782Spain Health research institute of Santiago de Compostela(iDiS) Santiago de Compostela 15782Spain State Key Laboratory of Quality research in Chinese Medicine Institute of Chinese Medical Sciences(ICMS)University of MacaoMacao 999078China Polymer Therapeutics Laboratory and CiBErONC Prince Felipe research Centre Valencia E-46012Spain Structure and Cell Biology of Viruses Lab CIC bioGUNEBasque Research and Technology Alliance(BRTA)Derio 48160Spain ALBA Synchrotron Light Source Experiments DivisionCerdanyola del VallèsBarcelona 08290Spain iKErBASQUE Basque Foundation for ScienceBilbao 48009Spain

The current spotlight of cancer therapeutics is shifting towards personalized medicine with the widespread use of monoclonal antibodies(mAbs).Despite their increasing potential,mAbs have an intrinsic limitation related to their inability to cross cell membranes and reach intracellular *** offers promising solutions to overcome this limitation,however,formulation challenges *** challenges are the limited loading capacity(often insufficient to achieve clinical dosing),the complex formulation methods,and the insufficient characterization of mAb-loaded ***,we present a new nanocarrier consisting of hyaluronic acid-based nanoassemblies(HANAs)specifically designed to entrap mAbs with a high efficiency and an outstanding loading capacity(50%,w/w).HANAs composed by an mAb,modified HA and phosphatidylcholine(PC)resulted in sizes of~100 nm and neutral surface *** modeling identified the principal factors governing the high affinity of mAbs with the amphiphilic HA and *** composition and structural configuration were analyzed using the orthogonal techniques cryogenic transmission electron microscopy(cryo-TEM),asymmetrical flow field-flow fractionation(AF4),and small-angle X-ray scattering(SAXS).These techniques provided evidence of the formation of core-shell nanostructures comprising an aqueous core surrounded by a bilayer consisting of phospholipids and amphiphilic *** vitro experiments in cancer cell lines and macrophages confirmed HANAs’low toxicity and ability to transport mAbs to the intracellular *** reproducibility of this assembling process at industrial-scale batch sizes and the long-term stability was *** conclusion,these results underscore the suitability of HANAs technology to load and deliver biologicals,which holds promise for future clinical translation.

关键词： monoclonal antibody nanoparticles hyaluronic acid characterization particle size computational modeling

High-speed silicon photonic electro-optic Kerr modulation

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Photonics research 2024年第1期12卷 51-60页

作者： jONATHAN PELTiEr WEiWEi ZHANG LEOPOLD VirOT CHriSTiAN LAFFOrGUE LUCAS DENiEL DELPHiNE MArriS-MOriNi GUY AUBiN FArAH AMAr DENH TrAN XiNGZHAO YAN CALLUM G.LiTTLEjOHNS CArLOS alonso-rAMOS KE Li DAViD j.THOMSON GrAHAM rEED LAUrENT ViViEN University Paris-Saclay CNRSCentre for Nanoscience and Nanotechnology(C2N)Palaiseau 91120France University Grenoble Alpes CEALETIGrenoble 38000France Optoelectronics research Centre Zepler Institute for Photonics and NanoelectronicsFaculty of Engineering and Physical SciencesUniversity of SouthamptonSouthampton SO171BJUK

Silicon-based electro-optic modulators contribute to easing the integration of high-speed and low-power consumption circuits for classical optical communications and data *** the plasma dispersion modulation,an alternative solution in silicon is to exploit the DC Kerr effect,which generates an equivalent linear electro-optical effect enabled by applying a large DC electric *** some theoretical and experimental studies have shown its existence in silicon,limited contributions relative to plasma dispersion have been achieved in high-speed modulation so *** paper presents high-speed optical modulation based on the DC Kerr effect in silicon PiN *** contributions of both plasma dispersion and Kerr effects have been analyzed in different waveguide configurations,and we demonstrated that the Kerr induced modulation is dominant when a high external DC electric field is applied in PiN ***-speed optical modulation response is analyzed,and eye diagrams up to 80 Gbit/s in NrZ format are obtained under a *** of 30 *** work paves the way to exploit the Kerr effect to generate high-speed Pockels-like optical modulation.

关键词： waveguide dispersion effect

Soil carbon characterization along the profile of two forest soils under Quercus pyrenaica

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journal of Forestry research 2020年第2期31卷 591-600页

作者： A.P.Fernandez-Getino j.L.alonso-Prados M.i.Santin-Montanya UPF-DTEVPF Instituto Nacional de Investigacion y Tecnologia Agraria y AlimentariaINIACtra.A Corunakm 7.528040 MadridSpain Dpto.Proteccion Vegetal Instituto Nacional de Investigacion y Tecnologia Agraria y AlimentariaINIACtra.A Corun akm 7.528040 MadridSpain

in light of concerns over climate change and increasing levels of CO2 in the atmosphere,it is of importance to investigate soil organic matter in Mediterranean forests at a profile ***-depth studies of the organic fraction are also of interest to improve understanding of carbon balance and to facilitate modelling of carbon fixation in forest *** research evaluates the relationships between diverse parameters such as colour,content,and form of soil organic matter(SOM).Two Quercus pyrenica ecosystems with soils classified as inceptisols with a xeric or dry moisture regime,and developed under a Mediterranean climate in Spain,were used to characterize SOM through the complete sequence of layers of the soil *** differentiating factor between the two ecosystems was slope *** was done using characteristics of humic substances(HS)as indicators of SOM turnover in *** analysis was used to further characterize the humic *** soil colour measurements are a tool for soil type classification and soil organic carbon prediction,the relation between HS colour measured by reflection and by transmission was determined in order to establish a relationship between measurement *** analysis and colour provided evidence of a different level of stabilization of HS from both soils,and between the different *** of humic acids was found to be greater in deeper horizons than in the surface *** inverse relationship between HS colour measured by reflection and by transmission was *** soils showed a clear trend in which horizons presenting lower absorbance numbers showed higher figures of hue and value.A more marked accumulation of humified compounds was found in pedons,(the smallest unit or volume of soil that contains all the soil types),in the less steep *** might be explained in terms of the physiographic position affecting infiltration behavior and exposure to runoff.

关键词： Organic matter turnover Colour humic substance(HS)by reflection Colour HS by transmission Humification index Mediterranean Quercus species

Analysis Of Urban Planning instruments in Comala,Colima,Mexico(1997-2009)from a Gender Perspective-A Secondary Publication

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journal of Architectural research and Development 2024年第1期8卷 93-101页

作者： E.j.García Espíritu P.Chung alonso i.BarajasÁvalos M.S.r.Covarrubias ruesga M.P.ramírez rivera National Technological institute of Mexico Mayor Benito Juárez CP 03330Mexico CityMexico

This work is carried out based on the analysis of urban planning instruments,taking the gender perspective as a *** arises from the inclusion of women in the participation of urban development,through an analysis of the gender gaps that have marked the history of women,the inequalities serve as a basis for carrying out this *** highlights the challenges we face today as a society in the process of building citizen participation,where we must all be recognized and have equal opportunities within the territory in which we *** article analyzes the extent to which the Municipal Urban Development Programs of the Mexican municipality of Comala,Colima,Mexico,consider the recommendations on gender and urbanism,established since the 1990s by international entities and applied transversally to urban planning *** differences are found between women and men in terms of empowerment and participation in urban territorial planning instruments,mainly in the oldest instrument(1997).Significant progress is observed in the most recent document and is currently in force in the municipality of Comala(2009).

关键词： Planning instruments Gender perspective Urban planning

Maschke Type Theorems for Weak Hopf Quasigroups

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Algebra Colloquium 2020年第2期27卷 213-230页

作者： j.N.alonso Alvarez j.M.Fernández Vilaboa r.González rodríguez Departamento de Matematicas Vniversidade de Vigo Campus Universitario Lagoas-MarcosendeE-36280 VigoSpain Departamento de Matematicas Universidade de Santiago de Compostela E-15771 Santiago de CompostelaSpain Departamento de Matematica Aplicada ii Universidade de Vigo Campus Universitario Lagoas-MarcosendeE-36310 VigoSpain

in this paper we give necessary and sufficient conditions for a comodule magma over a weak Hopf quasigroup to have a total integral,thus extending the theories developed in the Hopf algebra,weak Hopf algebra and non-associative Hopf algebra *** this result we also deduce a version of Maschke’s theorems for right(H,B)-Hopf triples associated to a weak Hopf quasigroup H and a right H-comodule magma B.

关键词： (weak)Hopf algebra (weak)Hopf quasigroup integral Maschke theorem

A Maschke Type Theorem for Weak Hopf Algebras

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Acta Mathematica Sinica,English Series 2008年第12期24卷 2065-2080页

作者： j.N.alonsoLVArEZ j.M.FErNNDEZViLABOA r.GONZLEZrODríGUEZ A.B.rODríGUEZrAPOSO Departamento de Matemáticas Universidad de Vigo. Lagoas-Marcosende Vigo. E-36200 Spain Departamento de lxebra. Universidad de Santiago de Compostela Santiago de Compostela. E-15771 Spain Departamento de Matemdtica Aplicada Ⅱ. Universidad de Vigo. Lagoas-Marcosende Vigo. E-36310 Spain Departamento delxebra Universidad de Santiago de CompostelaSantiago de Compostela E-15771 Spain

in this paper, we give a necessary and sufficient condition for a comodule algebra over a weak Hopf algebra to have a total integral, thus extending the classical theory developed by Doi in the Hopf algebra setting. Also, from these results, we deduce a version of Maschke＇s Theorem for （H, B）-Hopf modules associated with a weak Hopf algebra H and a right H-comodule algebra B.

关键词： Monoidal category weak Hopf algebra Hopf modules Maschke Theorem

MODELiNG HEADCUT DEVELOPMENT AND MiGrATiON iN UPLAND CONCENTrATED FLOWS

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international journal of Sediment research 2005年第4期20卷 281-294页

作者： Sean j. BENNETT Carlos V. alonso Department of Geography University at Buffalo Buffalo NY 14261-0055 USA USDA-ArS National Sedimentation Laboratory P.O. Box 1157 Oxford MS 38655

On hillslopes and agricultural fields, discrete areas of intense, localized soil erosion commonly take place in the form of migrating headcuts. These erosional features significantly increase soil loss and landscape degradation, yet the unsteady, transient, and migratory habits of headcuts complicate their phenomenological and erosional characterization. Here a unique experimental facility was constructed to examine actively migrating headcuts typical of upland concentrated flows. Essential components of the facility include a deep soil cavity with external drainage, rainfall simulator, capacity for overland flow, and a video recording technique for data collection. results from these experiments show that: (1) after a short period of adjustment, headcut migration attained a steady-state condition, where the rate of migration, scour hole geometry, and sediment discharge remain constant with time; (2) boundary conditions of higher rates of overland flow, steeper bed slopes, and larger initial headcut heights produced systematically larger scour holes with higher rates of soil erosion; and (3) during migration, the turbulent flow structure within the scour hole remained unchanged, consisting of an overfall nappe at the brink transitioning into a reattached wall jet with two recirculation eddies within the plunge pool. The systematic behavior of headcut development and migration enabled the application of modified jet impingement theory to predict with good success the characteristics of the impinging jet, the depth of maximum scour, the rate of headcut migration, and the rate of sediment erosion. These laboratory data and the analytical formulation can be used in conjunction with soil erosion prediction technology to improve the management of agricultural areas impacted by headcut development and ephemeral gully erosion.

关键词： Soil erosion Headcuts rills Gullies jet impingement

Micromechanical investigation of granular ratcheting using a discrete model of polygonal particles

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Particuology 2008年第6期6卷 390-403页

作者： Fernando alonso-Marroquín Hans B. Mhlhaus Hans j. Herrmann Earth Systems Science Computational Centre & School of Physical Sciences The University of Queensland Earth Systems Science Computational Centre The University of Queensland institut fr Baustoffe ETH-HenggerbergZrich

We use a two-dimensional model of polygonal particles to investigate granular ratcheting. ratcheting is a long-term response of granular materials under cyclic loading, where the same amount of permanent deformation is accumulated after each cycle. We report on ratcheting for low frequencies and extremely small loading amplitudes. The evolution of the sub-network of sliding contacts allows us to understand the micromechanics of ratcheting. We show that the contact network evolves almost periodically under cyclic loading as the sub-network of the sliding contacts reaches different stages of anisotropy in each cycle. Sliding contacts lead to a monotonic accumulation of permanent deformation per cycle in each particle. The distribution of these deformations appears to be correlated in form of vortices inside the granular assembly.

关键词： Granular systems Dynamics and kinematics of rigid bodies Molecular dynamics methods