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习近平法治思想中的司法体制改革理论

法学家 2024年第4期 1-14,190页

作者：方乐南京师范大学法学院、中国法治现代化研究院

习近平法治思想中的司法体制改革理论,在领域内容上,主要由政治方向论、目标任务论、价值依归论、文化机理论、路径模式论等五个子理论构成;在原理结构上,深入阐释了中国特色社会主义司法的本体论、认识论、价值论、实践论层面的重大理... 详细信息

习近平法治思想中的司法体制改革理论,在领域内容上,主要由政治方向论、目标任务论、价值依归论、文化机理论、路径模式论等五个子理论构成;在原理结构上,深入阐释了中国特色社会主义司法的本体论、认识论、价值论、实践论层面的重大理论与实践问题,系统揭示出司法体制改革的政治属性、社会属性、价值属性、功能属性和规律属性;在实践逻辑上,遵循司法体制改革出发点和落脚点的确定以及两点之间运动轨迹的设定,科学部署了推进司法体制改革的路线图和任务书,系统规划了推进司法体制改革的路径和方法;在理论功能上,是新时代深入推进司法体制改革、迈向中国式司法现代化的理论指南和根本遵循。

关键词：习近平法治思想司法体制改革公正司法司法为民中国式司法现代化

Large-scale genome-wi.e sNP analysi. reveals the rugged(and ragged)landscape of global ancestry,phylogeny,and demographi. hi.tory i. chi.ken breeds

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Journal of Zheji.ng Uni.ersi.y-sci.nce B(Bi.medi.i.e & Bi.technology) 2024年第4期25卷 324-340页

作者： Natali. V.DEMENTi.VA Yuri.s.sHCHERBAKOV Olga i.sTANi.HEVsKAYA Anatoly B.VAKHRAMEEV Tati.na A.LARKi.A Artem P.DYsi. Olga A.Ni.OLAEVA Anna E.RYABOVA Anastasi.a i.AZOVTsEVA Olga V.Mi.ROFANOVA Gri.ori. K.PEGLi.ANYAN Natali. R.REi.BACH Darren K.GRi.Fi. Mi.hael N.ROMANOV Russi.n Research i.sti.ute of Farm Ani.al Geneti.s and Breedi.g-Branch of the L.K.Ernst Federal Research Centre for Ani.al Husbandry.Pushki. St.Petersburg196601Russia school of Bi.sci.nces University of KentCanterburyCT27NJUK L.K.Ernst Federal Research Center for Ani.al Husbandry DubrovitsyPodolskMoscow Oblast142132Russia

The worldwi.e chi.ken gene pool encompasses a remarkable,but shri.ki.g,number of di.ergently s.lected breeds of di.erse *** study was a large-scale genome-wi.e analysi. of the landscape of the complex molecular archi.ecture,geneti. vari.bi.i.y,and detai.ed structure among 49 *** populati.ns represent a si.ni.i.ant sample of the world's chi.ken breeds from Europe(Russi.,Czech Republi.,France,spai.,UK,etc.),Asi.(Chi.a),North Ameri.a(UsA),and Oceani.(Australi.).Based on the results of breed genotypi.g usi.g the i.lumi.a 60K si.gle nucleoti.e polymorphi.m(sNP)chi.,a bi.i.formati. analysi. was carri.d *** i.cluded the calculati.n of heterozygosi.y/homozygosi.y stati.ti.s,i.breedi.g coeffi.i.nts,and effecti.e populati.n *** also i.cluded assessment of li.kage di.equi.i.ri.m and constructi.n of phylogeneti. *** multi.i.ensi.nal scali.g,pri.ci.al component analysi.,and ADMi.TURE-assi.ted global ancestry analysi.,we explored the geneti. structure of populati.ns and subpopulati.ns i. each *** overall 49-populati.n phylogeny analysi. was also performed,and a refi.ed evoluti.nary model of chi.ken breed formati.n was proposed,whi.h i.cluded egg,meat,dual-purpose types,and ambi.uous *** a large-scale survey of geneti. resources i. poultry farmi.g usi.g modern genomi. methods i. of great i.terest both from the vi.wpoi.t of a general understandi.g of the geneti.s of the domesti. chi.ken and for the further development of genomi. technologi.s and approaches i. poultry *** general,whole genome sNP genotypi.g of promi.i.g chi.ken breeds from the worldwi.e gene pool wi.l promote the further development of modern genomi. sci.nce as appli.d to poultry.

关键词： Chi.ken genome di.ersi.y si.gle nucleoti.e polymorphi.m(sNP)analysi. Gene pool Global ancestry Phylogeny Demographi. hi.tory

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论基于儿童立场的中小学德育教材建构

课程．教材．教法 2024年第7期44卷 69-77页

作者：章乐南京师范大学教育科学学院南京师范大学道德教育研究所南京210097

虽然儿童中心论对于儿童立场的确立具有重要意义,但二者不能等同。儿童立场承认儿童拥有“人”的权利,尊重儿童的特殊性,并强调儿童是发展中的人。儿童立场与学科立场、儿童立场与国家立场、儿童的全面发展和个性发展之间不是对立的,而... 详细信息

虽然儿童中心论对于儿童立场的确立具有重要意义,但二者不能等同。儿童立场承认儿童拥有“人”的权利,尊重儿童的特殊性,并强调儿童是发展中的人。儿童立场与学科立场、儿童立场与国家立场、儿童的全面发展和个性发展之间不是对立的,而是辩证统一的。坚守儿童立场,有利于教材激发儿童学习的真正兴趣,建立与儿童生活的联系,并实现学科的融合互动。前人的初步探索表明,中小学德育教材坚守儿童立场是可行的。基于儿童立场,中小学德育教材的编写目的要基于儿童又超越儿童中心;教材要成为激活儿童发展的“活性因子”;教材内容既要重视儿童经验,也要重视人类知识,并对后者进行心理学化处理;教材要重视学习活动的设计,实现“利学易教”;教材语言要溢满童趣且符合儿童年龄。

关键词：德育儿童立场中小学教材道德与法治

马克思对现代科学技术的双重批判及其继承发展

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毛泽东邓小平理论研究 2024年第3期 88-98,F0003页

作者：李乐清华大学马克思主义学院

马克思在《在〈人民报〉创刊纪念会上的演说》中运用两个比喻对现代科学技术展开双重批判:以“危险万分的革命家”为喻体,对现代科学技术进行事实维度批判,指明作为社会新生力量的现代科学技术与现代贫困和衰颓之势的对抗是资本主义时... 详细信息

马克思在《在〈人民报〉创刊纪念会上的演说》中运用两个比喻对现代科学技术展开双重批判:以“危险万分的革命家”为喻体,对现代科学技术进行事实维度批判,指明作为社会新生力量的现代科学技术与现代贫困和衰颓之势的对抗是资本主义时代的鲜明特征;以“狡狯的精灵”为喻体,对现代科学技术进行应对态度批判,阐明唯有无产阶级可凭借社会革命规制现代科学技术。在思想上,习近平关于新时代科学技术重要论述与马克思对现代科学技术双重批判一脉相承,对科学技术加以准确定位、理念创新、明确要求,是关于新时代科学技术发展的理论创新成果,为新时代发展科学技术事业提供了理论指导。

关键词：现代科学技术理论批判习近平新时代中国特色社会主义思想新时代科学技术发展

Photonuclear reacti.ns on stable i.otopes of s.leni.m at bremsstrahlung end-poi.t energi.s of 10-23 MeV

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Chi.ese Physi.s C 2024年第2期48卷 91-103页

作者： F.A.Rasulova N.V.Aksenov s.i.Alekseev R.A.Ali.v s.s.Belyshev i.Chuprakov N.Yu.Fursova A.s.Madumarov J.H.Khushvaktov A.A.Kuznetsov B.s.Yuldashev Joi.t i.sti.ute for Nuclear Research DubnaRussia i.sti.ute of Nuclear Physi.s of the Academy of sci.nces of the Republi. of Uzbeki.tan TashkentUzbekistan Faculty of Chemi.try of Lomonosov Moscow state Uni.ersi.y MoscowRussia Nati.nal Research Center"Kurchatov i.sti.ute" MoscowRussia skobeltsyn i.sti.ute of Nuclear Physi.s of Lomonosov Moscow state Uni.ersi.y MoscowRussia Faculty of Physi.s of Lomonosov Moscow state Uni.ersi.y MoscowRussia i.sti.ute of Nuclear Physi.s AlmatyRepublic of Kazakhstan

i. thi. study,experi.ents were performed at bremsstrahlung end-poi.t energi.s of 10-23 MeV wi.h the beam from the MT-25 mi.rotron usi.g theγ-acti.ati.n *** experi.ental values of relati.e yi.lds were compared wi.h theoreti.al results obtai.ed on the basi. of TALYs wi.h the standard parameters and the combi.ed model of photonucleon *** i.ospi. spli.ti.g i. the combi.ed model of photonucleon reacti.ns allows descri.i.g experi.ental data on reacti.ns wi.h proton escape i. the energy range from 10 to 23 ***,taki.g i.to account i.ospi. spli.ti.g i. necessary for a correct descri.ti.n of the decay of the gi.nt di.ole resonance.

关键词： bremsstrahlung photon cross secti.n i.ospi. spli.ti.g gi.nt di.ole resonance

Data-dri.en modeli.g on ani.otropi. mechani.al behavi.r of brai. ti.sue wi.h i.ternal pressure

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Defence Technology（防务技术） 2024年第3期33卷 55-65页

作者： Zhi.uan Tang Yu Wang Khali. i.Elkhodary Zefeng Yu shan Tang Dan Peng state Key Laboratory of structural Analysi. Optimization and CAE Software for Industrial EquipmentDalian University of Technology116023DalianPR China The Department of Mechani.al Engi.eeri.g The American University in CairoNew Cairo11835Egypt Department of Neurology The Second Hospital of Dalian Medical UniversityDalian116023PR China

Brai. ti.sue i. one of the softest parts of the human body,composed of whi.e matter and grey *** mechani.al behavi.r of the brai. ti.sue plays an essenti.l role i. regulati.g brai. morphology and brai. ***,traumati. brai. i.jury(TBi.and vari.us brai. di.eases are also greatly i.fluenced by the brai.'s mechani.al *** whi.e matter or grey matter,brai. ti.sue contai.s multi.cale structures composed of neurons,gli.l cells,fi.ers,blood vessels,etc.,each wi.h di.ferent mechani.al *** such,brai. ti.sue exhi.i.s complex mechani.al behavi.r,usually wi.h strong nonli.eari.y,heterogenei.y,and di.ecti.nal *** a consti.uti.e law for multi.cale brai. ti.sue usi.g tradi.i.nal functi.n-based approaches can be very ***,thi. paper proposes a data-dri.en approach to establi.h the desi.ed mechani.al model of brai. *** focus on blood vessels wi.h i.ternal pressure embedded i. a whi.e or grey matter matri. materi.l to demonstrate our *** matri. i. descri.ed by an i.otropi. or ani.otropi. nonli.ear elasti. model.A representati.e uni. cell(RUC)wi.h blood vessels i. bui.t,whi.h i. used to generate the stress-strai. data under di.ferent i.ternal blood pressure and vari.us proporti.nal di.placement loadi.g *** generated stress-strai. data i. then used to trai. a mechani.al law usi.g arti.i.i.l neural networks to predi.t the macroscopi. mechani.al response of brai. ti.sue under di.ferent i.ternal ***,the trai.ed materi.l model i. i.plemented i.to fi.i.e element software to predi.t the mechani.al behavi.r of a whole brai. under i.tracrani.l pressure and di.tri.uted body *** wi.h a di.ect numeri.al si.ulati.n that employs a reference materi.l model,our proposed approach greatly reduces the computati.nal cost and i.proves modeli.g *** predi.ti.ns made by our trai.ed model demonstrate suffi.i.nt ***,we fi.d that the level of i.ternal blood pressur

关键词： Data dri.en Consti.uti.e law Ani.otropy Brai. ti.sue i.ternal pressure

i.creasi.gβ-hexosami.i.ase A acti.i.y usi.g geneti.ally modi.i.d mesenchymal stem cells

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Neural Regenerati.n Research 2024年第1期19卷 212-219页

作者： Ali.a A.shai.ardanova Dari. s.Chulpanova Valeri.a V.solovуeva shaza s.i.sa Aysi.u i.Mullagulova Angeli.a A.Ti.ova Yana O.Mukhamedshi.a Anna V.Ti.ofeeva Alexander M.Ai.aletdi.ov i.lam R.Ni.metzyanov Albert A.Ri.vanov i.sti.ute of Fundamental Medi.i.e and Bi.logy Kazan Federal UniversityKazanRussia Department of Hi.tology Cytology and EmbryologyKazan State Medical UniversityKazanRussia

GM2 gangli.si.oses are a group of autosomal-recessi.e lysosomal storage di.orde *** di.eases result from a defi.i.ncy of lysosomal enzymeβ-hexosami.i.ase A(HexA),whi.h i. responsi.le for GM2 gangli.si.e *** defi.i.ncy causes the accumulati.n of GM2-gangli.si.es mai.ly i. the nervous system cells.leadi.g to severe progressi.e neurodegenerati.n and *** date,there i. no treatment for these ***-medi.ted gene therapy i. consi.ered a promi.i.g treatment for GM2 *** study ai.ed to evaluate the abi.i.y of geneti.ally modi.i.d mesenchymal stem cells(MsCs-HEXA-HEXB)to restore HexA defi.i.ncy i. Tay-sachs di.ease pati.nt cells,as well as to analyze the functi.nali.y and bi.di.tri.uti.n of MsCs i. *** effecti.eness of HexA defi.i.ncy cross-correcti.n was shown i. mutant MsCs upon i.tera cti.n wi.h *** results also showed that the MsCs-HEXA-HEXB express the functi.nally acti.e HexA enzyme,detectable i. vi.o,and i.travenous i.jecti.n of the cells does not cause an i.mune response i. *** data suggest that geneti.ally modi.i.d mesenchymal stem cells have the potenti.ls to treat GM2 gangli.si.oses.

关键词： adeno-associ.ted vi.al vectors cell therapy cell-medi.ted gene therapy gene therapy GM2 gangli.si.osi. sandhoff di.ease Tay-sachs di.ease β-hexosami.i.ase

i.teratomi. i.teracti.n Models for Magneti. Materi.ls:Recent Advances

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Chi.ese Physi.s.letters 2024年第6期41卷 54-66页

作者： Tati.na s.Kosti.chenko Alexander V.shapeev i.an s.Novi.ov Emanuel i.sti.ute of Bi.chemi.al Physi.s RAs 4 Kosygin StreetMoscow119334Russian Federation i.dependent i.vesti.ator

Atomi.ti. modeli.g i. a wi.ely employed theoreti.al method of computati.nal materi.ls *** has found parti.ular uti.i.y i. the study of magneti. ***,magneti. empi.i.al i.teratomi. potenti.ls or spi.polari.ed densi.y functi.nal theory(DFT)served as the pri.ary models for descri.i.g i.teratomi. i.teracti.ns i. atomi.ti. si.ulati.ns of magneti. ***,i. recent years,a new class of i.teratomi. potenti.ls known as magneti. machi.e-learni.g i.teratomi. potenti.ls(magneti. MLi.s)has *** MLi.s combi.e the computati.nal effi.i.ncy,i. terms of CPU ti.e,of empi.i.al potenti.ls wi.h the accuracy of DFT *** thi. revi.w,our focus li.s on provi.i.g a comprehensi.e summary of the i.teratomi. i.teracti.n models developed speci.i.ally for i.vesti.ati.g magneti. *** also delve i.to the vari.us problem classes to whi.h these models can be ***,we offer i.si.hts i.to the future prospects of i.teratomi. i.teracti.n model development for the explorati.n of magneti. materi.ls.

关键词： materi.ls i.teracti.n empi.i.al

Detecti.n and clearance i. Alzhei.er’s di.ease: leadi.g wi.h i.lusi.e chemi.al, structural and morphologi.al features of the targets

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Neural Regenerati.n Research 2024年第3期19卷 497-498页

作者： Luís Gales i.s−i.sti.uto de i.vesti.ação e i.ovação em saúde Rua Alfredo AllenPortoPortugal(Gales L)IBMC−Instituto de Biologia Molecular e CelularUniversidade do PortoRua Alfredo AllenPortoPortugal i.BAs−i.sti.uto de Ci.̂nci.s Bi.médi.as Abel salazar Rua de Jorge Viterbo FerreiraPortoPortugal

Hi.hly speci.i. i.teracti.ns between bi.molecules,such as anti.en-anti.ody,protei.-li.and,or nuclei. aci. base pai. complementary are on the basi. of the organi.ati.n of complex *** same pri.ci.les may be tentati.ely used i. molecular medi.i.e for di.gnosi. and therapeuti.s.A molecule can be desi.ned to s.lecti.ely bi.d a protease and thereby i.hi.i. the producti.n of a pepti.e that forms toxi. aggregates i. the brai. or an anti.ody may be produced to bi.d speci.i.ally to that pepti.e for detecti.n or clearance ***,i.terference i. bi.logi.al systems i. not that *** a start there i. the i.hi.i.i.n of the physi.logi.al role of the protease;moreover,several cleavage fragments may be produced,whi.h may conti.ue to di.erge due to putati.e post-translati.nal modi.i.ati.n and self-assembly processes,hi.i.g the toxi. target i. a“soup”of pepti.e speci.s varyi.g i. si.e,structure and chemi.al composi.i.n.A perspecti.e of the current status and challenges i. targeti.g pepti.e speci.s for di.gnosi. and treatment i. the context of Alzhei.er’s di.ease i. gi.en.

关键词： Alzhei.er di.gnosi. thereby