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Heart Fai.ure i. Chi.dren: Epi.emi.logi.al, Eti.logi.al and Di.gnosti. Aspects i. Di.mni.di. Chi.dren’s Hospi.al (Senegal)

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World Journal of Cardi.vascular Di.eases 2020年第1期10卷 12-18页

作者： M. Leye i. basse R. Godonou D. A. Affangla D. M. Ba N. N. Di.wara A. B. Si.abi.Si.abi.A. Phi.i.M. Di.um F. Di.by S. Akani.K. Gueye N. R. Di.gne B. M. Di.p Uni.é de Formati.n et de Recherche en sci.nces de la santé Université de Thiès Thiès Sénégal Faculté de Médeci.e de Pharmaci. et d’odontologi. Université Cheikh Anta Diop de Dakar Dakar Sénégal

i.troducti.n: Heart fai.ure i. a major cause of morbi.i.y and mortali.y i. chi.dren. The authors ai.ed to report the epi.emi.logi.al and eti.logi.al characteri.ti.s of heart fai.ure (HF) i. chi.dren i. Senegal. Pati.nts and Methods: Thi. was a retrospecti.e study conducted at the Chi.dren’s Hospi.al of Di.mni.di. (CHD) from 01-01-2016 to 31-12-2017. Chi.dren aged 0 to 15 years wi.h heart fai.ure confi.med by echocardi.graphy were i.cluded. Results: Si.ty-si. chi.dren were admi.ted for heart fai.ure. The prevalence of HF was 5.3‰. The mean age of the chi.dren was 41.59 months ± 53.35 months (range: 0 to 168 months). The 0 - 5 age group was the most represented (n = 48;72.72%). The HF concerned 38 boys and 28 gi.ls, a sex rati. (M/F) of 1.36. The majori.y of our pati.nts came from the semi.urban area (42.4%). The eti.logy of HF was represented i. order of frequency by congeni.al heart di.ease, rheumati. heart di.ease and cardi.myopathy wi.h 59.09% of cases, 22.73% of cases and 7.58% of cases respecti.ely. i. was unknown i. 4.54% of the cases. At echocardi.graphy, the left ventri.ular ejecti.n fracti.n (LVEF) was i.pai.ed (less than 50%) i. 19 pati.nts, i. 29.2% of cases wi.h an average of 64% +/- 15.16% (extremes: 24% and 86%). Anemi. was the comorbi.i.y most commonly associ.ted wi.h thei. condi.i.n (n = 33%;50%). Conclusi.n: Heart fai.ure i. chi.dren i. uncommon. The mai. eti.logy i. represented by congeni.al heart di.ease.

关键词： Heart Fai.ure Chi.dren Congeni.al Heart Di.ease Senegal

Evaluati.n and Characteri.ati.n of Executi.e Functi.n Di.orders after Stroke

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Open Journal of Psychi.try 2025年第1期15卷 16-23页

作者： El Hadji.Makhtar Ba Hi.ai.e Domi.i.ue Ewodo Touna Momar Camara Sokhna Seck Bocar Bai.a Di.dhi.u Racky Wade Fatoumata Ba Ndèye Awa Di.ye Mai.ouna Di.ye Ndi.ga Matar Gaye Adjaratou Di.ynabou Sow Anna Mbodj basse Mari.me Soda Di.p Lala Bouna Seck Ousmane Ci.se Khadi. Fall Adama Koundoul Mbayang Ndi.ye Ai.a Sylla Department of Psychi.try and Medi.al Psychology Fann National University Hospital Centre Dakar Senegal i.rahi.a Pi.rre Ndi.ye Neurosci.nce Cli.i. Dakar Senegal Occupati.nal Medi.i.e UCAD Dakar Senegal Department of Psychi.try and Human Physi.logy UGB Saint-Louis Senegal Department of Psychi.try EHMT This Senegal Department of Psychi.try Assane Seck University Ziguinchor Senegal

i.troducti.n: Stroke may have a negati.e i.pact on mental health and behavi.r. Cogni.i.e di.orders are common after stroke. They are rarely assessed i. current cli.i.al practi.e, parti.ularly i. our context. They consti.ute a real “i.vi.i.le” handi.ap. i. sub-Saharan Afri.a, we are not aware of any studi.s speci.i.ally assessi.g executi.e functi.ns. These functi.ns are at the heart of all adaptati.n processes to new or complex si.uati.ns. Thi. prompted the authors to carry out thi. study at the i.rahi.a Pi.rre Ndi.ye Neurosci.nce Department of the Fann Nati.nal Uni.ersi.y Hospi.al Centre (Senegal). Objecti.e and Methodology: The ai. of thi. study was to assess and characteri.e post-stroke alterati.ns i. executi.e functi.ns i. our context. We conducted a descri.ti.e cross-secti.nal study. i. took place over a 4-month peri.d from Apri. 1 to August 31, 2021. Pati.nts were matched to controls accordi.g to age, gender and educati.nal level. Executi.e functi.ns were assessed usi.g the Frontal Assessment Battery (FAB). Results: A total of 30 pati.nts wi.h stroke were enrolled. These pati.nts were matched to controls. The mean age of the pati.nts was 46.87 ± 17.65 years. For the control group, i. was 39.27 ± 12.33 years. The prevalence of executi.e functi.n di.orders was 20% i. post-stroke pati.nts. The majori.y of executi.e functi.ns assessed were i.pai.ed. Sensi.i.i.y to i.terference and envi.onmental autonomy were the only ones preserved. Conclusi.n: i.pai.ed executi.e functi.ns are common after stroke. They should be systemati.ally assessed i. all stroke pati.nts to ensure opti.al management.

关键词： Post-Stroke Mental Health Executi.e Functi.ns i.vi.i.le Di.abi.i.y Senegal

Legal Condi.i.ns for Water Uti.i.i.s Eco-i.novati.n as Energy Smart Water Uti.i.i.s

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Journal of Earth Sci.nce and Engi.eeri.g 2013年第9期3卷 644-654页

作者： Ellen Margrethe basse Department of Law School of Business and Social Sciences Aarhus University DK 8000 Denmark

Welfare and green growth rest heavi.y on an appropri.te supply of safe water, the provi.i.n of adequate sewerage, and on energy servi.es. These servi.es are i.terdependent, as water i. an i.tegral part of electri.-power generati.n; i. i. used di.ectly i. hydroelectri. generati.n, and i. i. used extensi.ely for cooli.g and emi.si.ns scrubbi.g i. thermoelectri. generati.n. Energy i. also an i.tegrated part of water servi.es, as sati.fyi.g water needs for supply, puri.i.ati.n, di.tri.uti.n, and treatment of wastewater requi.es energy sources. Water and energy uti.i.i.s are however regulated wi.hout a speci.i. focus on the i.terdependency of the two sectors and the possi.i.i.i.s to ensure sustai.able use of the resources and reducti.n of greenhouse gasses by a better coordi.ati.n. The arti.le explai.s the possi.i.i.i.s of sustai.able consumpti.n and producti.n of energy i. the water uti.i.i.s. i. hi.hli.hts EU legal framework that makes coordi.ati.n at nati.nal level possi.le, and i. gi.es examples and concludes--on the obstacles for the water uti.i.i.s＇ future as energy-smart uti.i.i.s that exi.t at the nati.nal level i. Denmark.

关键词： Resource effi.i.ncy energy smart technologi.s water uti.i.i.s legi.lati.n

^（99m）Tc－HMPAO－白细胞在探查骨关节感染中的临床应用

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中华核医学杂志 1995年第2期15卷 96-98页

作者：李彪 Barthe N basse-Cathali.al 上海第二医科大学附属瑞金医院核医学科法国波尔多第二大学附属ＰＥＬＬＥＧＲＩＮ医院核医学科

对２５例临床怀疑为骨关节感染的病人分别进行９９ｍＴｃ－亚甲基二膦酸（ＭＤＰ）骨显像和９９ｍＴｃ－６－甲基丙二胺肟（ＨＭＰＡＯ）－白细胞显像．结果表明：９９ｍＴｃ－ＭＤＰ骨显像在临床怀疑为感染的部位出现了异常的放射性浓... 详细信息

对２５例临床怀疑为骨关节感染的病人分别进行９９ｍＴｃ－亚甲基二膦酸（ＭＤＰ）骨显像和９９ｍＴｃ－６－甲基丙二胺肟（ＨＭＰＡＯ）－白细胞显像．结果表明：９９ｍＴｃ－ＭＤＰ骨显像在临床怀疑为感染的部位出现了异常的放射性浓聚区，其中３例在其他部位也出现了与骨折、无菌性坏死及类风湿性关节炎等有关的异常放射性浓聚区．９９ｍＴｃ－ＨＭＰＡＯ－白细胞显像１９例真阳性，４例真阴性，２例假阴性，无１例假阳性．２例假阴性病人有长期使用抗生素史．９９ｍＴｃ－ＨＭＰＡＯ－白细胞显像诊断感染的灵敏度为９０．５％，特异性为１００％，准确率为９２％，它为临床疑有骨关节感染病人的诊断提供了一种非创伤性的方法，并为临床治疗提供了依据．

关键词：关节感染放射性核素显像白细胞肟类诊断

Pro-i.flammatory cytoki.e;tumor-necrosi. factor-alpha (TNF-α) i.hi.i.s astrocyti. support of neuronal survi.al and neuri.es outgrowth

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Advances i. Bi.sci.nce and Bi.technology 2013年第8期4卷 73-80页

作者： Ebtesam M. Abd-El-basse Department of Anatomy Faculty of Medicine Kuwait University Kuwait City Kuwait

Reacti.e astrogli.si. has been i.pli.ated i. the fai.ure of axonal regenerati.n i. adult mammali.n Central Nervous System (CNS). i. i. our hypothesi. that i.flammatory cytoki.es act upon astrocytes to alter thei. bi.chemi.al and physi.al properti.s, whi.h may i. turn be responsi.le for the fai.ure of neuronal regenerati.n. We have therefore exami.ed the effect of tumor-necrosi. factor-alpha (TNF-α) on the abi.i.y of astrocytes to support the survi.al of the corti.al neurons and the growth of the neuri.es. Mouse astrocytes and corti.al neuronal cultures were prepared. i. was observed that when neurons were cultured i. absence of astrocytes only a few of them grew and survi.ed only for 5-6 days. These neurons had small cell bodi.s and few, short neuri.es. However, when the same numbers of neurons were cultured on the top of astrocytes, more neurons grew and survi.ed up to 16-18 days. They had bi.ger cell bodi.s and many long branched neuri.es that formed anestamosi.g networks. The neurons then coalesced and the neuri.es formed thi.k bundles. When the same numbers of neurons were grown on the top of astrocytes pre-treated wi.h TNF-α, few neurons survi.ed up to 13 days. The neuri.es of the survi.ed neurons were shorter than neuri.es of neurons grown on normal astrocytes and di. not form bundles. i. addi.i.n, TNF-α sti.ulated the expressi.n of gli.l fi.ri.lary aci.i. protei. (GFAP) by astrocytes. These results support that the pro-i.flammatory cytoki.e, TNF-α modulates the gli.si. and that the astrocyti. cell supports neuronal survi.al and neuri.e outgrowth.

关键词： Astrocytes Neurons Cytoki.es Tumor-Necrosi. Factor-Alpha

联合应用NK细胞及CTL对黑色素瘤B16细胞的影响

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重庆医学 2012年第9期41卷 878-880页

作者：余少鸿汤荣春 Per H basse 云南省昆明市第一人民医院普外科 650011 美国匹兹堡大学肿瘤中心宾夕法尼亚州匹兹堡152131863

目的探讨联合应用自然杀伤(NK)细胞及细胞毒T细胞(CTL)对黑色素瘤B16细胞的作用。方法提取NK细胞及CTL,分别用白细胞介素-2(i.-2)(6 000、600i./L)及植物血凝素(8μg/mL)活化,流式细胞仪检测细胞表面受体,将NK细胞及CTL互为靶细胞及效... 详细信息

目的探讨联合应用自然杀伤(NK)细胞及细胞毒T细胞(CTL)对黑色素瘤B16细胞的作用。方法提取NK细胞及CTL,分别用白细胞介素-2(i.-2)(6 000、600i./L)及植物血凝素(8μg/mL)活化,流式细胞仪检测细胞表面受体,将NK细胞及CTL互为靶细胞及效应细胞进行细胞毒性实验;以黑色素瘤B16细胞为靶细胞检测CTL的杀伤率。结果 NK细胞表面受体NK1.1+的百分比在87%以上,NKp46+在90%以上;CTL表面受体CD3+的百分比在99%以上,CD8+在98%以上。NK细胞与CTL相互无细胞毒性,联合应用NK细胞与CTL明显增加对黑色素瘤B16细胞的杀伤作用。结论联合应用NK细胞及CTL对黑色素瘤B16细胞有协同杀伤作用。

关键词：黑色素瘤,实验性 T淋巴细胞,细胞毒性自然杀伤细胞

NK细胞上清液提高CTL细胞对肿瘤细胞杀伤力及机制的研究

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重庆医学 2012年第21期41卷 2136-2138页

作者：余少鸿汤荣春 Per H basse 云南省昆明市第一人民医院普外科 650011 美国匹兹堡大学肿瘤中心匹兹堡pa152131863

目的研究从白细胞介素2(i.-2)、i.-2+i.-12、i.-2+i.-18、i.-2+i.-12+i.-18活化的NK细胞提取的上清液是否能提高细胞毒性T细胞(CTL)对黑色素瘤细胞的杀伤率及其机制。方法提取NK细胞,i.-2 6 000i./mL、i.-2 6 000i./mL+i.-12 10ng/mL,i.-2 6 000i./mL+i.-18 100ng/mL,i.-2 6 000i./mL+i.-12 10ng/mL+i.-18 100ng/mL活化,3d后提取上清液,与M05细胞培养过夜,流式细胞仪检测肿瘤细胞表面Ⅰ类组织相容性抗原(MHCⅠ)表达,以其为靶细胞检测CTL细胞对M05细胞杀伤率。结果 NK细胞上清液提高M05细胞表面MHCⅠ分子表达及CTL细胞对M05细胞杀伤率。结论 NK细胞上清液能够增强CTL对肿瘤细胞的杀伤作用。

关键词：自然杀伤细胞白细胞介素12 白细胞介素18 组织相容性抗原Ⅰ类黑色素瘤细胞

Autoanti.odi.s to GFAP (gli.l fi.ri.lary aci.i. protei.) and to dopami.e i. pati.nts wi.h acute and chroni. cerebrovascular di.оrders

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Health 2010年第12期2卷 1366-1371页

作者： P.R. Kamchatnov A.V. Chugunov N.Yu. Ruleva S.F. Dugi. D.A. basse B.A. Abusueva L.i. Buri.chkovskaya E.i. Gusev 不详

We have studi.d the level of autoanti.odi.s to neurospeci.i. protei.s and neurotransmi.ters i. pati.nts wi.h di.ferent forms of i.chemi. brai. lesi.n. 49 pati.nts wi.h acute (i.hemi. stroke) and chroni. cerebrovascular di.ease, 14 pati.nts wi.h i.hemi. heart di.ease and control group (35 healthy subjects) were i.vesti.ated. The serum level of autoanti.odi.s to gli.l fi.ri.lary aci.i. protei. (GFAP) and to dopami.e (D) was determi.ated by ELi.A. The content of autoanti.odi.s to GFAP and D i. pati.nts wi.h i.chemi. heart di.ease was practi.ally i.enti.al. The pati.nts wi.h acute and chroni. cerebrovas-cular di.eases had the si.ni.i.ally i.creased level of autoanti.odi.s. The level of autoanti.odi.s to GFAP i. pati.nts wi.h acute vascular acci.ents (i.chemi. stroke) wi.h favorable outcome was si.ni.i.antly hi.her than i. pati.nts wi.h chroni. cerebral i.chemi.. The obtai.ed data allowed us to consi.er serum level of autoanti.odi.s to GFAP as a marker of i.chemi. brai. lesi.n, and to suppose further potenti.l role of thi. autoanti.odi.s i. cerebrovascular di.ease progressi.n.

关键词： Acute and Chroni. Cerebrovascular Di.eases i.chemi. Stroke Autoanti.odi.s to Gli.l Fi.ri.lary Aci.i. Protei. Autoanti.odi.s to Dopami.e

Management of Severe Acute Malnutri.i.n i. a Senegalese Paedi.tri. Hospi.al

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Open Journal of Pedi.tri.s 2021年第2期11卷 198-207页

作者： Ndi.gou Seck i.ri.sa basse Dji.ri. Boi.o Younoussa Keïta Lami.e Thi.m Ali.u Abdoulaye Ndongo Ndéye Rama Di.gne-Gueye Servi.e de péDi.tri. Centre Hospitalier Régional de Saint-Louis Saint-Louis Sénégal H&oci.c pi.al pour Enfants de Di.mni.di. Bargny Sénégal Servi.e de péDi.tri. Centre Hospitalier Abass Ndao Dakar Sénégal Servi.e de péDi.tri. H&oci.c pi.al Ari.ti.e Ledantec Dakar Sénégal Servi.e de PéDi.tri. H&ocirc pi.al de la Pai. Boucoutte Ziguinchor Sénégal

Malnutri.i.n i. a global health problem. i. i. very common i. developi.g countri.s where i. contri.utes to an i.crease i. morbi.i.y and mortali.y, especi.lly among chi.dren under fi.e years of age. The mai. objecti.e of thi. study was to descri.e the management of severe acute malnutri.i.n (SAM) i. chi.dren si. months to fi.e years of age hospi.ali.ed at Di.mni.di. Chi.dren’s Hospital (DCH). This was an epidemiological, retrospective, descriptive and cross-sectional study of children aged six to 59 months hospitalized at DCH for SAM. The study took place over a 12-month period (from January 1, 2018 to December 31, 2018). During the study period, 67 children were admitted for SAM, representing a hospital prevalence of 8.4%. The majority (88%) children were less than 24 months old. Reasons for consultations were dominated by diarrhea (57.5%) vomiting (38.8%). Complications related to SAM were mainly: anaemia (74.6%), infections (85%) and severe acute dehydration (40.3%). Factors associated with SAM were young age (infants under 24 months of age), poverty, the first four children of a sibling, poor behaviour of food diversification. The average length of hospitalization was 12 days. The nutritional recovery rate was 73.1% and lethality was 3%. Conclusion: The prevention of malnutrition must involve the fight against poverty, an optimal and well-diversified diet, monitoring the nutritional status of children up to five years of agei.y:Verdana;">.

关键词： Severe Acute Malnutri.i.n Chi.dren Compli.ati.ns Ri.k Factors Lethali.y