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Resi.ents'percepti.n of sustai.able touri.m i. protected mountai. areas:the case of Asturi.s

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Journal of Mountai. Sci.nce 2022年第12期19卷 3597-3614页

作者： MAGADAN-Di.Z Marta Ri.AS-GARCi. Jesus i. Faculty of busi.ess and Communi.ati.n Universidad Internacional de La RiojaAvda.de la Paz 137Logrono 26o06Spain

Spai. i. the country wi.h the most bi.sphere Reserves i. the world,52,and Asturi.s,wi.h 7,ranks fi.st among the si.gle-provi.ce Autonomous *** touri.t i.terest i. these natural spaces i. i.creasi.g,but li.tle or nothi.g i. known about how the resi.ents of these natural spaces percei.e the touri.t *** mai. objecti.e of thi. research was to evaluate the resi.ents’percei.ed changes i. protected mountai. areas i. Asturi.s concerni.g the envi.onmental,soci.cultural,and economi. di.ensi.ns related to touri.m acti.i.y wi.h survey methods and vari.us quanti.ati.e *** fi.di.gs obtai.ed were the followi.g:fi.stly,there were si.ni.i.ant di.ferences between the resi.ents’soci.demographi. characteri.ti.s and thei. percepti.ns of touri.m i.pacts;secondly,there were posi.i.e relati.nshi.s between the resi.ents’percei.ed touri.m economi.,envi.onmental and soci.cultural i.pacts and thei. general atti.ude towards touri.m development;and thi.dly,the more posi.i.e the resi.ents’atti.ude towards touri.m development,the more li.ely resi.ents acti.ely support i.s further *** fi.di.gs i.di.ate the wi.li.gness of resi.ents to get i.volved and parti.i.ate i. the touri.m acti.i.y,so poli.ymakers should i.pli.ate resi.ents i. deci.i.nmaki.g on local touri.m *** conclusi.n,long-term moni.ori.g of resi.ents’evoluti.n of thei. percepti.ns and atti.udes i. necessary to achi.ve sustai.able touri.m development.

关键词： Sustai.able touri.m Touri.ts’percepti.n Survey method Regressi.n analysi. Asturi.s

ATP as ani.di.ator of bi.mass acti.i.y i. thermophi.i. upflow anaerobi. sludge blanket reactor

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Journal of Envi.onmental Sci.nces 2000年第3期12卷 380-384页

作者： CHEN Hong (Department of Envi.onmental Sci.nce and Engi.eeri.g ,Zheji.ng Uni.ersi.y ,Hangzhou 31 0 0 2 7,Chi.a) 浙江大学浙江杭州 3 1 0 0 2

Thi.worki.vesti.atedthebi.massacti.i.yi.athermophi.i.upflowanaerobi.sludgeblanket (UASb )reactorof wastewatertreatment .Syntheti.texti.ewastewaterwi.hpH 1 0— 1 1 ,CODlevelof2 0 0 0— 30 0 0mg/Lwastested .Cellularadenosi.e tri.hosphate (ATP)i.volati.esoli.s (VS ;mgATP/gVS)wasmeasuredandexpressedasspeci.i.ATPcontenttocomparethe bi.massacti.i.yi.upzoneandlowerzonei.UASbreactor .Theresultshowsthatthespeci.i.ATPcontentbasedontotalvolati.e soli.s (VS)i.lowerzone ( 0 .0 4 6mgATP/gVSaverage)i.muchlowerthanthati.upzone ( 0 .62mgATP/gVSaverage)duetohi.hcontentofi.acti.ebi.massandhi.hpHi.lowerzone .TheSATPi.upzonei.creasesasHRTi.creasesandapproachestoa maxi.umvalueof 0 .85mgATP/gVSatHRTof 7h ,thendecreases .i.showsmostofthetotalVSi.upzonerepresentacti.e bacteri.lbi.massatHRTof 7h .Rateofsubtractuti.i.*** effectofHRTonSATPi.lowerzonei.notassi.ni.i.antasonSATPi.upzone .Thebuffercapaci.yofthethermophi.i.UASb reactori.verygood .i.i.theacti.i.yofsludgegranulesi.lowerzonethatgi.etheUASbreactorsuchagoodbuffercapaci.ytothei.lethi.hpH .

关键词： ATP bi.massacti.i.y UASbreactor

Coupled Perturbed Modes over Slopi.g Penetrable bottom

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Chi.ese Physi.s Letters 2017年第7期34卷 126-129页

作者： Fei.Long Zhu Eri. i. Thorsos Feng-Hua Li State Key Laboratory of Acousti.s Institute of Acoustics Chinese Academy of Sciences Beijing 100190 Uni.ersi.y of Chi.ese Academy of Sci.nces Beijing 100049 Appli.d Physi.s Laboratory University of Washington WA 98105 USA

i. envi.onments wi.h water depth vari.ti.ns, one-way modal soluti.ns i.volve mode coupli.g. Hi.ham and Ti.dle developed an accurate and fast approach usi.g perturbati.n theory to locally determi.e the change i. mode functi.ns at steps. The method of Hi.ham and Ti.dle i. li.i.ed to low frequency （≤250 Hz）. We extend the coupled perturbati.n method, thus i. can be appli.d to hi.her frequenci.s. The approach i. descri.ed and some examples are gi.en.

关键词： Coupled Perturbed Modes over Slopi.g Penetrable bottom

i.vesti.ati.n on the mechani.al properti.s of si.tered porous copper compacts

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Chi.a Parti.uology 2007年第6期5卷 391-394页

作者： Yasser M.Z. Ahmed Mohamed i. Ri.d Ahmed i. Zaky Mohammed Abdel-Azi. Mohamed M.H. Shalabi Central Metallurgi.al Research and Development i.sti.ute CMRDI El-Felzat Street El-Tabbin P.O. Box 87 Helwan Cairo Egypt

i. li.e wi.h recent attenti.n on porous metals havi.g low and medi.m porosi.i.s i. the range of 20-50%, thi. paper studi.s the effect of porosi.y on the mechani.al properti.s of si.tered copper compacts. Experi.ents were desi.ned to i.vesti.ate the effect of porosi.y, appli.d stress and sli.i.g veloci.y on the wear rate of copper compacts, leadi.g to the fi.di.g that the effects of both porosi.y and appli.d stress of the wear test on the wear rate are approxi.ately si.i.ar and hi.her than that of sli.i.g veloci.y. The i.vesti.ati.n concerni.g the effect of porosi.y on compressi.e strength i.di.ated that the stress-strai. curve of hi.h-porosi.y compact exhi.i.ed i.enti.i.ble ulti.ate strength poi.ts, though low-porosi.y compact showed di.ti.ct stages of elasti. plasti. behavi.r.

关键词： Porous copper Wear rate Compressi.e strength Experi.ental desi.n techni.ue

Deep learni.g i.enti.i.ati.n of novel autophagi. protei.-protei. i.teracti.ns and experi.ental vali.ati.n of becli. 2-Ubi.ui.i. 1 axi. i. tri.le-negati.e breast cancer

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Oncology research 2025年第1期33卷 67-81页

作者： Xi.ng Li.Wenke Ji. Li.eng Wu Huan Wang Xi. Xi. Wei.Huang b O Li. State Key Laboratory of Southwestern Chi.ese Medi.i.e Resources School of Pharmacy and College of Medical Technology Chengdu University of Traditional Chinese Medicine Chengdu 611137 China. Department of bi.therapy Cancer Center and State Key Laboratory of Biotherapy West China Hospital Sichuan University Chengdu 610041 China.

background:Tri.le-negati.e breast cancer (TNbC), characteri.ed by i.s lack of tradi.i.nal hormone receptors and HER2, presents a si.ni.i.ant challenge i. oncology due to i.s poor response to conventi.nal therapi.s. Autophagy i. an i.portant process for mai.tai.i.g cellular homeostasi., and there are currently autophagy bi.markers that play an effecti.e role i. the cli.i.al treatment of tumors. i. contrast to targeti.g protei. acti.i.y, i.terventi.n wi.h protei.-protei. i.teracti.n (PPi. can avoi. unrelated crosstalk and regulate the autophagy process wi.h mi.i.al i.terference pathways.Methods:Here, we employed Nai.e bayes, Deci.i.n Tree, and k-Nearest Nei.hbors to eluci.ate the complex PPi.network associ.ted wi.h autophagy i. TNbC, ai.i.g to uncover novel therapeuti. targets. Meanwhi.e, the candi.ate protei.s i.teracti.g wi.h becli. 2 were i.i.i.lly screened i. MDA-Mb-231 cells usi.g becli. 2 as bai. protei. by i.munopreci.i.ati.n-mass spectrometry assay, and the i.teracti.n relati.nshi. was veri.i.d by molecular docki.g and CO-i. experi.ents after i.tersecti.n. Colony formati.n, cellular i.munofluorescence, cell scratch and 3-(4,5-Di.ethylthi.zol-2-yl)-2,5-di.henyltetrazoli.m bromi.e (MTT) tests were used to predi.t the cli.i.al therapeuti. effects of mani.ulati.g candi.ate PPi.Results:by developi.g three PPi.classi.i.ati.n models and analyzi.g over 13,000 datasets, we i.enti.i.d 3733 previ.usly unknown autophagy-related PPi.. Our network analysi. revealed the central role of becli. 2 i. autophagy regulati.n, uncoveri.g i.s i.teracti.ns wi.h 39 newly i.enti.i.d protei.s. Notably, the CO-i. studi.s i.enti.i.d the substanti.l i.teracti.n between becli. 2 and Ubi.ui.i. 1, whi.h was anti.i.ated by our model and di.covered i. i.munopreci.i.ati.n-mass spectrometry assay results. Subsequently, i.vesti.ati.ns showed that overexpressi.g becli. 2 i.creased Ubi.ui.i. 1, promoted autophagy-dependent cell death, and i.hi.i.ed proli.erati.n and metastasi. i. MDA-Mb-231 cells.

关键词： Arti.i.i.l i.telli.ence (Ai. Autophagy becli. 2 Protei.-protei. i.teracti.ns (PPi. Tri.le-negati.e breast cancer (TNbC) Ubi.ui.i. 1

An i.telli.ent Agent Approach to Adapti.e Project Management

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Tsi.ghua Sci.nce and Technology 2008年第S1期13卷 121-125页

作者： i. Ourdev S. AbouRi.k Hole School of Constructi.n Department of Civil and Environmental Engineering

Thi. paper presents the i.i.i.l steps to i.tegrati.g a di.tri.uted di.crete event si.ulati.n system wi.h a framework for i.telli.ent software agents. The resulti.g system has a si.ulati.n component that i. based on the hi.h-level archi.ecture (HLA) and an agent component that i.plements the beli.f-desi.e-i.tenti.n (bDi. approach to agent modelli.g. The archi.ecture i. connected to a real-ti.e i.formati.n source. The framework was successfully appli.d to a real-li.e moni.ori.g system for a tunnel-bori.g machi.e excavati.n project that helped wi.h forecasti.g and managi.g the project ti.eli.es i. response to the changes i. the uncertai. excavati.n envi.onment. Thi. project i. presented as a test case and demonstrates encouragi.g results for i.tegrati.e modelli.g of large-scale problems wi.h elements of uncertai.ty.

关键词： i.telli.ent agents adapti.e project management beli.f-desi.e-i.tenti.n (bDi. hi.h-level archi.ecture (HLA) excavati.n project di.crete event si.ulati.n bayesi.n modelli.g uncertai.ty

Spi. texturi.g i. quantum wi.es wi.h Rashba and Dresselhaus spi.-orbi. i.teracti.ns and i.-plane magneti. fi.ld

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Chi.ese Physi.s b 2016年第1期25卷 750-756页

作者： b Gi.i.S Saki.oglu i.Sokmen Physi.s Department Graduate School of Natural and Applied SciencesDokuz Eyll Universityizmir 35390Turkey Physi.s Department Faculty of ScienceDokuz Eyll Universityizmir 35390Turkey

i. thi. work, we i.vesti.ate the effects of i.terplay of spi.-orbi. i.teracti.n and i.-plane magneti. fi.lds on the electroni. structure and spi. texturi.g of paraboli.ally confi.ed quantum wi.e. Numeri.al results reveal that the competi.g effects between Rashba and Dresselhaus spi.--orbi. i.teracti.ns and the external magneti. fi.ld lead to a compli.ated energy spectrum. We fi.d that the spi. texturi.g owi.g to the coupli.g between subbands can be modi.i.d by the strength of spi.- orbi. coupli.gs as well as the magni.ude and the ori.ntati.n angle of the external magneti. fi.ld.

关键词： spi.-orbi. coupli.g quantum wi.e spi. texture

Dynami.al behavi.r for a Cross-Di.fusi.n Model of Forest

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Communi.ati.ns i. Nonli.ear Sci.nce and Numeri.al Si.ulati.n 1997年第4期2卷 216-219页

作者： Yuanqu Li.2 (School of Mathemati.al Sci.nces,Peki.g Uni..,bei.i.g1 0 0 871 ) E- mai.:lyqe@sxx0 .*** School of Mathemati.al Sci.nces Peking University Beijing 100871 China

i. thi. paper,the exi.tence of a bounded global attractor for a Cross- Di.fusi.n model of forest wi.h homogeneous Di.i.hlet boundary condi.i.n i. proved under some condi.i.n on the parameters.

关键词： Age- structured forest model cross- di.fusi.n equi.alent norm L yapunov functi.n α - contracti.n gradi.nt semi.roup

Fri.dmann Cosmology wi.h bulk Vi.cosi.y:A Concrete Model for Dark Energy

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Communi.ati.ns i. Theoreti.al Physi.s 2009年第8期52卷 377-382页

作者： MENG Xi.-He D0U Xu Department of Physi.s Nankai University Tianjin 300071 China Kavli.i.sti.ute for Theoreti.al Physi.s Chi.a at the Chi.ese Academy of Sci.nces （Ki.PC-CAS） Beijing 100190 China

The uni.erse content i. consi.ered as a non-perfect flui. wi.h bulk vi.cosi.y and can be descri.ed by a general equati.n of state （endowed some devi.ti.n from the conventi.nally assumed cosmi. perfect flui. model）. An expli.i.ly bulk vi.cosi.y dark energy model i. proposed to confront consi.tently wi.h the current observati.nal data sets by stati.ti.al analysi. and i. shown consi.tent wi.h （not devi.ted away much from） the concordant A Cold Dark Matter （CDM） model by compari.g the decelerati.g parameter. Also we compare our relati.ely si.ple vi.cosi.y dark energy model wi.h a more compli.ated one by contrast wi.h the concordant ACDM model and fi.d our model i.proves for the vi.cosi.y dark energy model bui.di.g. Fi.ally we di.cuss the perspecti.es of dark energy probes for the comi.g years wi.h observati.ns.

关键词： dark energy cosmology bulk vi.cosi.y uni.i.ati.n of dark matter and dark energy