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Acti.ated Protei. C Resi.tance i. Pati.nts wi.h Pre-Eclampsi. i. Lagos, Ni.eri.

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Open Journal of Obstetri.s and Gynecology 2024年第4期14卷 575-590页

作者： Nosi.ot O. Davi.s Ti.i.ope A. Adeyemo Sunday i. Omi.aki. Akani.yene A. Udousoro Kabi.u A. Rabi. Department of Haematology and blood Transfusi.n College of Medicine University of Lagos Lagos Nigeria Department of Obstetri.s and Gynaecology College of Medicine University of Lagos Lagos Nigeria Department of Obstetri.s and Gynaecology Lagos State University Teaching Hospital Lagos Nigeria Department of Obstetri.s and Gynaecology College of Medicine Lagos State University Lagos Nigeria

Background: Preeclampsi. i. reported to compli.ate 2% - 8% of pregnanci.s globally and i. an i.portant cause of maternal and peri.atal morbi.i.y and mortali.y. The aeti.logy and pathogenesi. are sti.l poorly understood and substanti.l i.provement has not been made i. the predi.ti.n, preventi.n and treatment of the di.ease. Objecti.e: To compare the frequency of acti.ated protei. C resi.tance (APC-R) i. pati.nts wi.h pre-eclampsi. to that of normotensi.e pregnant women and to determi.e the correlati.n between acti.ated protei. rati. (APC-rati.) and the severi.y of pre-eclampsi.. Methodology: A cross-secti.nal study was carri.d out i. 100 pre-eclampti. pati.nts and 100 normotensi.e pregnant controls. The APC-rati. was determi.ed usi.g the modi.i.d acti.ated parti.l thromboplasti. ti.e. Study parti.i.ants wi.h APC-rati. of less than 2.0 were defi.ed as havi.g APC-R. Data was analyzed usi.g SPSS versi.n 22.0. Results: Mean APC-rati. was si.ni.i.antly lower i. pre-eclampti.s (2.89 ± 1.70) compared to normotensi.e pregnant women (3.57 ± 1.06) (p = 0.0008) and the levels were also hi.her i. mi.d (2.95 ± 1.15) compared to severe pre-eclampti.s (2.62 ± 1.14). The frequency of APC-R was 26% among women wi.h pre-eclampsi. compared to 4% among normotensi.e controls (p = 0.000). Among 100 pre-eclampti. women 7 (21.2%) out of 33 wi.h mi.d pre–eclampsi. had APC-R, whi.e 19 (28.4%) out of 67 wi.h severe pre-eclampsi. had APC-R. APC-rati. had a si.ni.i.ant negati.e correlati.n wi.h mean arteri.l blood pressure (r = −0.324;p = 0.000) and protei.uri. (r = −0.379;p = 0.000) among study parti.i.ants. Conclusi.n: The frequency of acti.ated protei. c resi.tance i. si.ni.i.antly hi.her i. pre-eclampti.s compared to normotensi.e pregnant women and thi. i. more pronounced i. those wi.h severe pre-eclampsi. compared wi.h those wi.h mi.d di.ease. APC-R may therefore be used as a marker of severi.y i. the di.ease.

关键词： Acti.ated Protei. C Resi.tance Acti.ated Protei. C Rati. Pre-Eclampsi.

Post processi.g of addi.i.e manufactured Mg alloys:Current status,challenges,and opportuni.i.s

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Journal of Magnesi.m and Alloys 2024年第4期12卷 1283-1310页

作者： Nooruddi. Ansari.Fati.a Ghassan Alabtah Mohammad i.Albakri.Marwan Khrai.heh Mechani.al Engi.eeri.g Program Texas A&M University at QatarP.O.Box 23874DohaQatar

Magnesi.m(Mg)and i.s alloys are emergi.g as a structural materi.l for the aerospace,automobi.e,and electroni.s i.dustri.s,dri.en by the i.perati.e of wei.ht *** are also drawi.g notable attenti.n i. the medi.al i.dustri.s owi.g to thei. bi.degradabi.i.y and a lower elasti. modulus comparable to *** abi.i.y to manufacture near-net shape products featuri.g i.tri.ate geometri.s has sparked huge i.terest i. addi.i.e manufacturi.g(AM)of Mg alloys,reflecti.g a transformati.n i. the manufacturi.g ***,AM of Mg alloys presents more formi.able challenges due to i.herent properti.s,parti.ularly suscepti.i.i.y to oxi.ati.n,gas trappi.g,hi.h thermal expansi.n coeffi.i.nt,and low soli.i.i.ati.n *** leads to defects such as porosi.y,lack of fusi.n,cracki.g,delami.ati.n,resi.ual stresses,and i.homogenei.y,ulti.ately i.fluenci.g the mechani.al,corrosi.n,and surface properti.s of AM Mg *** address these i.sues,post-processi.g of AM Mg alloys are often needed to make them sui.able for *** present arti.le revi.ws all post-processi.g techni.ues adapted for AM Mg alloys to date,i.cludi.g heat treatment,hot i.ostati. pressi.g,fri.ti.n sti. processi.g,and surface *** uti.i.ati.n of these methods wi.hi. the hybri. AM process,employi.g i.terlayer post-processi.g,i. also *** post-processi.g condi.i.ns are reported,and thei. i.fluence on the mi.rostructure,mechani.al,and corrosi.n properti.s are ***,future prospects and research di.ecti.ns are proposed.

关键词： Magnesi.m alloy Addi.i.e manufacturi.g Post-processi.g Heat treatment Hi.

Effecti.eness of external prestressi.g i. enhanci.g the non-ducti.e hanger fai.ure mechani.m i. rei.forced concrete i.verted T-beams

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Fronti.rs of Structural and Ci.i. Engi.eeri.g 2024年第7期18卷 1050-1065页

作者： Ahmed M.ATTA Reda N.BEHi.Y Mohammed i.HARAZ Structural Engi.eeri.g Department Faculty of EngineeringTanta UniversityTanta 33511Egypt Ni.e Hi.her i.sti.ute for Engi.eeri.g and Technology Mansoura 11001Egypt

Recently,i.verted T-beams have been used i. rei.forced concrete(RC)bri.ges to support transverse precast *** T-beams,contrary to practi.e wi.h conventi.nal beams,are loaded on the flanges upper *** loadi.g confi.urati.n causes hanger fai.ure due to the generati.n of verti.al tensi.e stresses near the bottom of the *** key purpose of thi. study i. to i.vesti.ate the effi.i.ncy of verti.al external prestressi.g stai.less-steel bars i. mi.i.ati.g non-ducti.e hanger fai.ure i. rei.forced concrete i.verted *** experi.ental study on si. i.verted-T beams,i.cludi.g two un-strengthened speci.ens,was carri.d *** study showed that the value of the prestressi.g level had a consi.erable i.pact on the performance of hanger mechani.m i. relati.n to crack pattern,ulti.ate loads,cracki.g behavi.r,load-deflecti.n,strai.s,and *** experi.ental results i.di.ated that the suggested method for strengtheni.g i.verted T-beams had effi.acy i. reduci.g the seri.usness of the non-ducti.e hanger fai.ure and resulted i. a strength i.crease of up to 53% when compared to that of the un-strengthened ***,two analyti.al models for esti.ati.g the hanger capaci.y and the average crack wi.th of the strengthened RC i.verted T-beams were *** models that were proposed exhi.i.ed a hi.h degree of agreement wi.h the experi.ental results.

关键词： RC bri.ges i.verted T-beams strengtheni.g hanger fai.ure external prestressi.g

i.munotherapy i. gastri. cancer wi.h li.er metastasi.:Challenges and opportuni.i.s

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World Journal of Gastroi.testi.al Surgery 2024年第6期16卷 1513-1516页

作者： Murat Bardakçi.Yakup Ergun Department of Medi.al Oncology Diyarbakır Gazi Yasargil Training and Research HospitalDiyarbakir 021000KayapinarTürkiye Department of Medi.al Oncology Antalya City HospitalAntalya 07080Türkiye

i. thi. edi.ori.l,we revi.w the arti.le by Li. et al publi.hed i. the World Journal of Gastroi.testi.al Surgery i.vesti.ati.g the effi.acy and safety of i.munotherapy i. pati.nts wi.h gastri. cancer(GC)and li.er ***,the fi.th most com-monly di.gnosed mali.nancy worldwi.e,presents a si.ni.i.ant challenge due to i.s multi.actori.l eti.logy and a gri. prognosi. for unresectable or recurrent *** advent of i.mune checkpoi.t i.hi.i.ors(i.i.)has revoluti.ni.ed oncology;yet li.er metastasi. has been associ.ted wi.h reduced response rates,progressi.n-free survi.al,and overall survi.al i. vari.us *** Che-ckMate-649 and KEYNOTE-859 tri.ls demonstrated promi.i.g results wi.h i.i. i. advanced GC,parti.ularly i. pati.nts wi.h li.er ***,a meta-analysi. of li.er metastati. soli. tumors revealed worse outcomes wi.h i.i.,hi.h-li.hti.g the need for further *** combi.ed therapi.s,i.cludi.g i.i. wi.h local treatments,show promi.e i. i.provi.g outcomes,the nuanced landscape of i.i. i. li.er metastati. GC necessi.ates conti.ued research for robust *** current contradi.ti.ns i. the li.erature underscore the i.por-tance of cauti.us i.terpretati.n and the explorati.n of tai.ored approaches to enhance cli.i.al effi.acy i. thi. challengi.g pati.nt populati.n.

关键词： Gastri. cancer Li.er metastasi. i.munotherapy i.mune checkpoi.t i.-hi.i.ors Transarteri.l chemoemboli.ati.n Tumor mi.roenvi.onment

The Adsorpti.n Properti.s of TEMPO Oxi.i.ed Cellulose agai.st the Mi.ture of Methylene Blue and Rhemazol Yellow FG

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Journal of Renewable Materi.ls 2024年第8期12卷 1369-1382页

作者： i.Putu Mahendra Karti.a Di.i.a Program Studi.Ki.i. Fakultas SainsInsitut Teknologi SumateraJalan Terusan RyacuduWay HuwiJati AgungLampung Selatan35365Indonesia

TEMPO/NaOCl/NaBr treatment si.ni.i.antly i.creased the number of negati.e charges on the cellulose *** concentrati.ns of NaOCl,5 and 30 mmol/g of cellulose,were used i. thi. *** number of carboxyl groups i. the two cellulosi. samples oxi.i.ed usi.g TEMPO/NaOCl/NaBr was 0.5160 and 1.8461 mmol/g of cellulose,*** oxi.i.ed cellulose samples treated wi.h 5 and 30 mmol/g NaOCl exhi.i.ed hi.her crystalli.i.y,at 81.15%and 80.14%,respecti.ely,compared to untreated cellulose,whi.h had a crystalli.i.y of 75.95%.The pH effect i.di.ated that the hi.hest adsorpti.n capaci.y for methylene blue was achi.ved under alkali.e condi.i.ns(pH 9),whi.e the hi.hest adsorpti.n capaci.y for rhemazol yellow FG was achi.ved under aci.i. *** ki.eti. model of TEMPO-oxi.i.ed cellulose for methylene blue and rhemazol yellow FG conformed to the pseudo-second-order *** i.i.i.l concentrati.n parameter revealed that the i.otherm model for the adsorpti.n of methylene blue and rhemazol yellow FG by TEMPO-oxi.i.ed cellulose conformed to the Langmui. *** dye removal effi.i.nci.s for methylene blue and rhemazol yellow FG usi.g TEMPOoxi.i.ed cellulose(30 mmol/g)were approxi.ately 80.17%and 59.52%,*** results demonstrate that TEMPO/NaOCl/NaBr-oxi.i.ed samples can effecti.ely separate cati.ni. and ani.ni. dye ***,the use of TEMPO-oxi.i.ed cellulose showed good regenerati.n capabi.i.y,mai.tai.i.g more than 95%of i.s adsorpti.n capaci.y after 8 cycles.

关键词： Cellulose TEMPO oxi.ati.n cati.ni. and ani.ni. dyes dye separati.n

VR-based di.i.al twi. for remote moni.ori.g of mi.i.g equi.ment:Archi.ecture and a case study

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虚拟现实与智能硬件（中英文） 2024年第2期6卷 100-112页

作者： Jovana PLAVŠi. i.i.a Mi.KOVi.Norman BKeevi. Norman B.Keevi. i.sti.ute of Mi.i.g Engi.eeri.g University of British ColumbiaVancouverBC V6T 1Z4Canada

Background Tradi.i.nal methods for moni.ori.g mi.i.g equi.ment rely pri.ari.y on vi.ual i.specti.ns,whi.h are ti.e-consumi.g,i.effi.i.nt,and *** arti.le i.troduces a novel approach to moni.ori.g mi.si.n-cri.i.al systems and servi.es i. the mi.i.g i.dustry by i.tegrati.g vi.tual reali.y(VR)and di.i.al twi.(DT)***-based DTs enable remote equi.ment moni.ori.g,advanced analysi. of machi.e health,enhanced vi.uali.ati.n,and i.proved deci.i.n *** Thi. arti.le presents an archi.ecture for VR-based DT development,i.cludi.g the developmental stages,acti.i.i.s,and stakeholders i.volved.A case study on the condi.i.n moni.ori.g of a conveyor belt usi.g real-ti.e syntheti. vi.rati.n sensor data was conducted usi.g the proposed *** study demonstrated the appli.ati.n of the methodology i. remote moni.ori.g and i.enti.i.d the need for further development for i.plementati.n i. acti.e mi.i.g *** arti.le also di.cusses i.terdi.ci.li.ari.y,choi.e of tools,computati.nal resources,ti.e and cost,human i.volvement,user acceptance,frequency of i.specti.n,multi.ser envi.onment,potenti.l ri.ks,and appli.ati.ns beyond the mi.i.g *** The fi.di.gs of thi. study provi.e a foundati.n for future research i. the domai. of VR-based DTs for remote equi.ment moni.ori.g and a novel appli.ati.n area for VR i. mi.i.g.

关键词： Vi.tual reali.y Di.i.al twi. Condi.i.n moni.ori.g Mi.i.g equi.ment

Landau quanti.ati.n effects on dampi.g Kawahara soli.ons i. electron–posi.ron–i.n plasma i. rotati.g i.ni.ed medi.m

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Communi.ati.ns i. Theoreti.al Physi.s 2024年第10期76卷 143-152页

作者： E i.El-Awady S Hussai. N Akhtar Department of Physi.s Faculty of Science Port Said University Theoreti.al Physi.s Di.i.i.n (TPD) PINSTECH

For the dynami.s of three-di.ensi.nal electron–posi.ron–i.n plasmas, a flui. quantum hydrodynami. model i. proposed by consi.eri.g Landau quanti.ati.n effects i. dense ***–neutral colli.i.ns i. the presence of the Cori.li. force are also consi.ered. The appli.ati.n of the reducti.e perturbati.n techni.ue produces a wave evoluti.n equati.n represented by a damped Korteweg–de Vri.s equati.n. Thi. equati.n, however, i. i.suffi.i.nt for descri.i.g waves i. our system at very low di.persi.n coeffi.i.nts. As a result, we consi.ered the hi.hest-order perturbati.n, whi.h resulted i. the damped Kawahara equati.n. The effects of the magneti. fi.ld, Landau quanti.ati.n, the rati. of posi.ron densi.y to electron densi.y, the rati. of posi.ron densi.y to i.n densi.y, and the di.ecti.n cosi.e on li.ear di.persi.n laws as well as soli.on and conoi.al soluti.ns of the damped Kawahara equati.n are explored. The understandi.g from thi. research can contri.ute to the broader fi.ld of astrophysi.s and ai. i. the i.terpretati.n of observati.nal data from whi.e dwarfs.

关键词： Cori.li. force Kawahara equati.n Landau quanti.ati.n magnetoplasmas quantum plasma soli.ary and cnoi.al waves

Transi.i.n from oceani. subducti.n to conti.ental colli.i.n:i.si.hts from volcanogeni.-sedi.entary rocks of the Tannuola terrane(northern Central Asi.n Orogeni. Belt)

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Geosci.nce Fronti.rs 2024年第4期15卷 41-60页

作者： E.V.Vetrov N.i.Vetrova V.S.Sobolev i.sti.ute of Geology and Mi.eralogy SB RAS Koptyuga ave.3NovosibirskRussia

Magmati.m associ.ted wi.h oceani. subducti.n plays a domi.ant role i. crustal growth duri.g the Earth's *** Tannuola terrane,si.uated i. the northern Central Asi.n Orogeni. Belt(CAOB),i. a key area to understandi.g oceani. subducti.n and i.i.i.l colli.i.n processes i. the northern *** order to i.vesti.ate the swi.ch from subducti.n to colli.i.n setti.gs,detai.ed fi.ld mappi.g,zi.con SHRi.P U-Pb geochronologi.al and whole-rock geochemi.al studi.s of volcanogeni.-sedi.entary rocks from the Tannuola terrane were carri.d *** U-Pb ages i.di.ate multi.stage volcani.m lasted at least 30 Ma from~540 to~510 Ma,that can be di.i.ed i.to three events:the late Edi.caran(before~540 Ma),the early Cambri.n(~520 Ma)and the mi.dle Cambri.n(~510 Ma).These ages are i.ter-preted to the i.i.i.l,mai. and fi.al stages of oceani. subducti.n duri.g the late Proterozoi.-early *** the late Edi.caran,tholei.ti. basalts wi.h hi.hεNd(t)values(from+7.4 to+8.5)were *** formi.g by the 10%-30%parti.l melti.g of spi.el-garnet mantle source duri.g slab *** the early Cambri.n,transi.i.nal from tholei.ti. to calc-alkali.e basalti. rocks wi.hεNd(t)value(+5.6)and coeval i.termedi.te-felsi. volcani. rocks wi.h si.i.arεNd(t)values(+5.9 and+6.5)*** early Cambri.n basalti. rocks are i.terpreted to be deri.ed by 10%-30%parti.l melt-i.g of a depleted mantle source metasomati.ed by slab-deri.ed flui.s released from the subducti.g ocea-ni. *** mi.dle Cambri.n calcalkali.e basalti. rocks wi.hεNd(t)value of+6.2 mi.ht be emplaced as a result of low(5%-10%)degree parti.l melti.g of a metasomati.ed mantle followed by fracti.nal crys-talli.ati.n of cli.opyroxene and *** i.termedi.te-felsi. volcani. rocks wi.hεNd(t)values from+6.0 to+6.8 were formed through fracti.nati.n of the juveni.e Neoproterozoi. *** mi.dle Cambri.n volcani.m i. i.terpreted to be tri.gered by the slab break-off duri.g the transi.i.n to a colli.i.nal se

关键词： i.land-arc magmati.m Edi.caran Cambri.n zi.con U-Pb dati.g Nd i.otopes Central asi.n orogeni. belt

Effect of a Commerci.l Extract of Green Tea and a Pure Catechi. on Two Vei.lonella strai.s

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Advances i. Mi.robi.logy 2024年第6期14卷 340-350页

作者： Jorge A. Yáñez-Santos Vi.ney Li.o-Agui.ar Elsa i. Castañeda-Roldan Jorge Gi.on Li.i. Cedi.lo Centro de Detecci. Bi.molecular Benemrita Universidad Autnoma de Puebla Puebla Mexico Facultad de Estomatologa Puebla Mexico

The catechi. Epi.allocatechi.-3-O-Gallate (EGCG) whi.h i. found i. of Green Tea extracts (GTE), di.plays a vari.ty of mi.robi.i.al properti.s. i. i. largely beli.ved that EGCG i.hi.i.s the growth of cari.geni. and peri.dontopathi. bacteri.. Objecti.e: i. thi. paper we compared the i.hi.i.ory acti.i.y of EGCG and a commerci.l GTE on the growth of Vei.lonella parvula. Chlorhexi.i.e was used as posi.i.e control. Methodology: V. parvula ATCC 10790 and a cli.i.al i.olate obtai.ed from a peri.dontal di.ease pati.nt were cultured i. the presence of EGCG or a commerci.l GTE, and the measurements of bacteri.l growth i.hi.i.i.n were compared to the values obtai.ed wi.h 0.12 and 0.2% chlorhexi.i.e. Results: Chlorhexi.i.e i.hi.i.ed bacteri.l growth, however i. contrast to a previ.us report, nei.her EGCG nor the GTE showed any effect on bacteri.l growth. Conclusi.ns: The data show and confi.m that chlorhexi.i.e i. a growth i.hi.i.or of V. parvula whi.e EGCG and GTE do not di.play such effect.

关键词： Vei.lonella Parvulla Chlorhexi.i.e Green Tea Catechi.