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Recent trends i. bone metastasi. treatments:A hi.tori.al compari.on usi.g the new Katagi.i.score system

World Journal of Cli.i.al Cases 2024年第15期12卷 2499-2505页

作者： Kenji.matsuda Kazuhi.o Shi.azu Hanae Shi.ozaki.Koji.Fukuda Tai.hi.Yoshi.a Dai.i.Taguchi.Kyoko Nomura Hi.oyuki.Shi.ata Department of Cli.i.al Oncology Akita University Graduate School of MedicineAkita 010-8543Japan Department of Envi.onmental Health Sci.nce and Publi. Health Akita University Graduate School of MedicineAkita 010-8543Japan Department of Comprehensi.e Cancer Control Akita University Graduate School of MedicineAkita 010-8543Japan

BACKGROUND Bone metastasi. has vari.us negati.e *** of dai.y li.i.g(ADL)and quali.y of li.e(QOL)can be si.ni.i.antly decreased,survi.al may be i.pacted,and medi.al expenses may *** i. esti.ated that at least 5%cancer pati.nts mi.ht be sufferi.g from bone *** 2016,we publi.hed the Comprehensi.e Gui.eli.es for the Di.gnosi. and Treatment of Bone *** then,the therapeuti. outcomes for pati.nts have gradually *** li.e expectancy i. a major determi.ant of surgi.al i.terventi.n,the strategy should be modi.i.d i. the prolongati.n of survi.al i. to be *** To moni.or how bone metastasi. treatment has changed before and after launch of our gui.eli.es for bone *** For advanced cancer pati.nts wi.h bone metastasi. who vi.i.ed the Department of Cli.i.al Oncology at Aki.a Uni.ersi.y hospi.al between 2012 and 2023,parameters i.cludi.g the si.e and number of bone metastases,laboratory data,and survi.al ti.e,were extracted from electroni. medi.al records and the Katagi.i.score was *** associ.ti.n wi.h survi.al was determi.ed for each *** Data from 136 pati.nts were *** 1-year survi.al rate for the poor prognosi. group wi.h a hi.her Katagi.i.score was 20.0%i. thi. study,whi.h was 6%and an apparent i.provement from 2014 when the scori.g system was *** factors si.ni.i.antly affecti.g survi.al i.cluded fi.e or more bone metastases than less(P=0.0080),and treatment wi.h chemotherapy(Pi.yi.g agents(P=0.0175)and i.mune checkpoi.t i.hi.i.ors(P=0.0128).i. recent years,advances i. vari.us treatment methods have extended the survi.al peri.d for pati.nts wi.h advanced *** i. necessary not only to si.ply extend survi.al ti.e,but also to mai.tai. ADL and i.prove *** Vari.us therapeuti. i.terventi.ns i.cludi.g surgi.al approach for bone metastasi.,whi.h i. a di.order of locomotor organs,are i.creasi.gly *** and scori.g system for p

关键词： Bone metastasi. New Katagi.i.scori.g system Prognosi. i.mune check poi.t i.hi.i.ors Survi.al

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The current status and future development of hi.h-temperature conventi.nal superconducti.i.y

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Nati.nal Sci.nce Revi.w 2024年第7期11卷 18-20页

作者： Mi.hai. i.Eremets Hi.h Pressure Chemi.try and Physi.s Group Max-Planck-Institut für Chemie

Thi. survey hi.hli.hts key advancements i. hi.h-temperature superconducti.i.y i. hydrogen-ri.h materi.ls, emphasi.i.g the robust evi.ence and reproduci.i.i.y of superconducti.i.y under challengi.g experi.ental condi.i.ns of megabar pressures. i. the near future, achi.vi.g room-temperature superconducti.i.y i. hi.hly probable, and the fi.ld i. expected to transi.i.n towards near-ambi.nt-pressure superconducti.i.y.

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Usi.g fracture-based conti.uum modeli.g of coupled geomechani.al-hydrologi.al processes for numeri.al si.ulati.n of hydrauli. fracturi.g

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Journal of Rock Mechani.s and Geotechni.al Engi.eeri.g 2024年第5期16卷 1582-1599页

作者： Goodluck i.Ofoegbu GNO Modeli.g Research LLC. San AntonioTX78253USA

Thi. paper descri.es numeri.al si.ulati.n of hydrauli. fracturi.g usi.g fracture-based conti.uum modeli.g(FBCM)of coupled geomechani.al-hydrologi.al processes to evaluate a techni.ue for hi.h-densi.y fracturi.g and fracture *** si.ulati.ns are i.novati.e because of modeli.g di.crete fractures expli.i.ly i. conti.uum analysi..A key advantage of FBCM i. that fracture i.i.i.ti.n and propagati.n are modeled expli.i.ly wi.hout changi.g the domai. gri.(*** re-meshi.g).Further,multi.le reali.ati.ns of a preexi.ti.g fracture di.tri.uti.n can be analyzed usi.g the same domai. *** si.ulated hydrauli. fracturi.g techni.ue consi.ts of pressuri.i.g multi.le wells si.ultaneously:i.i.i.lly wi.hout permeati.g flui.s i.to the rock,to seed fractures uni.ormly and at hi.h densi.y i. the wall rock of the wells;followed by flui. i.jecti.n to propagate the seeded fracture densi.y *** combi.es the ease of conti.uum modeli.g wi.h the potenti.l accuracy of modeli.g di.crete fractures and fracturi.g *** are modeled as pi.cewi.e planar based on i.tersecti.ns wi.h domai. elements;fracture geometry stored as conti.uum properti.s i. used to calculate parameters needed to model i.di.i.ual fractures;and rock behavi.r i. modeled through tensori.l aggregati.n of the behavi.r of di.crete fractures and unfractured *** are presented for previ.usly unfractured rock and for rock wi.h preexi.ti.g fractures of hori.ontal,shallow-di.pi.g,steeply di.pi.g,or verti.al *** of a si.gle-well model are used to determi.e the pattern and spaci.g for a multi.le-well *** results i.lustrate hi.h-densi.y fracturi.g and fracture cagi.g through si.ultaneous flui. i.jecti.n i. multi.le wells:for previ.usly unfractured rock or rock wi.h preexi.ti.g shallow-di.pi.g or hori.ontal fractures,and i. si.u verti.al compressi.e stress greater than *** preexi.ti.g fractures are steeply di.pi.g or verti.al,and consi.eri.g the same i. si.u

关键词： Di.crete fracture Fracture-based conti.uum modeli.g Fracture cagi.g Hi.h-densi.y fracturi.g Hydrauli. fracturi.g Preexi.ti.g fracture

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A Radi.l Basi. Functi.n Method wi.h i.proved Accuracy for Fourth Order Boundary Value Problems

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Journal of Appli.d Mathemati.s and Physi.s 2024年第7期12卷 2559-2573页

作者： Scott A. Sarra Derek Musgrave Marcus Stone Joseph i. Powell Department of Mathemati.s Marshall University Huntington WV USA

Accurately approxi.ati.g hi.her order deri.ati.es i. an i.herently di.fi.ult problem. i. i. shown that a random vari.ble shape parameter strategy can i.prove the accuracy of approxi.ati.g hi.her order deri.ati.es wi.h Radi.l Basi. Functi.n methods. The method i. used to solve fourth order boundary value problems. The use and locati.n of ghost poi.ts are exami.ed i. order to enforce the extra boundary condi.i.ns that are necessary to make a fourth-order problem well posed. The use of ghost poi.ts versus solvi.g an overdetermi.ed li.ear system vi. least squares i. studi.d. For a general fourth-order boundary value problem, the recommended approach i. to ei.her use one of two novel sets of ghost centers i.troduced here or else to use a least squares approach. When usi.g ei.her ghost centers or least squares, the random vari.ble shape parameter strategy results i. si.ni.i.antly better accuracy than when a constant shape parameter i. used.

关键词： Numeri.al Parti.l Di.ferenti.l Equati.ns Boundary Value Problems Radi.l Basi. Functi.n Methods Ghost Poi.ts Vari.ble Shape Parameter Least Squares

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A Novel Approach for Developi.g a Li.ear Regressi.n Model wi.hi. Logi.ti. Cluster Usi.g Sci.i.-Learn

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Journal of Data Analysi. and i.formati.n Processi.g 2024年第3期12卷 348-369页

作者： Nwosu Ambrose Gi.bert i. O. Ai.ufua Choji.Davou Nyap Departments of Computer Sci.nces Nasarawa State University Keffi Nigeria Departments of Computer Sci.nces University of Jos Jos Nigeria

Due to the rapi. development of logi.ti. i.dustry, transportati.n cost i. also i.creasi.g, and fi.di.g trends i. transportati.n acti.i.i.s wi.l i.pact posi.i.ely i. i.vestment i. transportati.n i.frastructure. There i. li.i.ed li.erature and data-dri.en analysi. about trends i. transportati.n mode. Thi. thesi. delves i.to the operati.nal challenges of vehi.le performance management wi.hi. logi.ti.s clusters, a cri.i.al aspect of effi.i.nt supply chai. operati.ns. i. ai.s to address the i.sues faced by logi.ti.s organi.ati.ns i. opti.i.i.g thei. vehi.le fleets’ performance, essenti.l for seamless logi.ti.s operati.ns. The study’s core desi.n i.volves the development of a predi.ti.e logi.ti.s model based on regressi.n, focused on forecasti.g, and evaluati.g vehi.le performance i. logi.ti.s clusters. i. encompasses a comprehensi.e li.erature revi.w, research methodology, data sources, vari.bles, feature engi.eeri.g, and model trai.i.g and evaluati.n and F-test analysi. was done to i.enti.y and veri.y the relati.nshi.s between attri.utes and the target vari.ble. The fi.di.gs hi.hli.ht the model’s effi.acy, wi.h a low mean squared error (MSE) value of 3.42, i.di.ati.g i.s accuracy i. predi.ti.g performance metri.s. The hi.h R-squared (R2) score of 0.921 emphasi.es i.s abi.i.y to capture relati.nshi.s between i.put characteri.ti.s and performance metri.s. The model’s trai.i.g and testi.g accuracy further attest to i.s reli.bi.i.y and generali.ati.n capabi.i.i.s. i. i.terpretati.n, thi. research underscores the practi.al si.ni.i.ance of the fi.di.gs. The regressi.n-based model provi.es a practi.al soluti.n for the logi.ti.s i.dustry, enabli.g i.formed deci.i.ns regardi.g resource allocati.n, mai.tenance planni.g, and deli.ery route opti.i.ati.n. Thi. contri.utes to enhanced overall logi.ti.s performance and customer servi.e. By addressi.g performance gaps and embraci.g modern logi.ti.s technologi.s, the study supports the ongoi.g evoluti.n of vehi.le performance management

关键词： Mean Squared Error R2 Score F-Test MSE

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Severe aspi.ati.n pneumoni. i. the elderly

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Journal of i.tensi.e Medi.i.e 2024年第3期4卷 307-317页

作者： Sebasti.n Ocrospoma Marcos i.Restrepo Di.i.i.n of Pulmonary Di.eases&Cri.i.al Care Medi.i.e University of Texas Health San AntonioSan AntonioTXUSA Secti.n of Pulmonary&Cri.i.al Care Medi.i.e South Texas Veterans Health Care SystemSan AntonioTXUSA

The global populati.n i. agi.g at an unprecedented rate,resulti.g i. a growi.g and vulnerable elderly populati.n i. need of effi.i.nt comprehensi.e healthcare servi.es that i.clude long-term care and ski.led nursi.g *** thi. context,severe aspi.ati.n pneumoni.,a condi.i.n that carri.s substanti.l morbi.i.y,mortali.y,and fi.anci.l burden,especi.lly among elderly pati.nts requi.i.g admi.si.n to the i.tensi.e care uni.,has attracted greater *** pneumoni. i. defi.ed as a pulmonary i.fecti.n related to aspi.ati.n or dysphagi. i. *** epi.odes of coughi.g on food or li.ui. i.take,a hi.tory of relevant underlyi.g condi.i.ns,abnormali.i.s on vi.eofluoroscopy or water swallowi.g,and gravi.y-dependent shadow di.tri.uti.n on chest i.agi.g are among the clues that suggest *** wi.h aspi.ati.n pneumoni. tend to be elderly,frai.,and sufferi.g from more comorbi.i.i.s than those wi.hout thi. ***,we comprehensi.ely address the epi.emi.logy,cli.i.al characteri.ti.s,di.gnosi.,treatment,preventi.n,and prognosi. of severe aspi.ati.n communi.y-acqui.ed pneumoni. i. the elderly to opti.i.e care of thi. hi.h-ri.k demographi.,enhance outcomes,and mi.i.i.e the healthcare costs associ.ted wi.h thi. *** preventi.e measures and effecti.e management strategi.s i. vi.al i. ensuri.g the well-bei.g of our agi.g populati.n.

关键词： Aspi.ati.n pneumoni. Aged Cri.i.al i.lness Swallowi.g di.orders Frai.ty Anti.acteri.l agents

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On Some Properti.s of Graph of Prefi. Code

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Journal of Appli.d Mathemati.s and Physi.s 2024年第4期12卷 1571-1581页

作者： Ni.olai.i. Krai.i.kov Mi.hai. E. Abramyan Bori. F. Melni.ov Faculty of Computati.nal Mathemati.s and Cyberneti.s Shenzhen MSU-BIT University Shenzhen China Department of Algebra and Di.crete Mathemati.s Southern Federal University Rostov-on-Don Russian Federation

We i.vesti.ate decomposi.i.n of codes and fi.i.e languages. A pri.e decomposi.i.n i. a decomposi.i.n of a code or languages i.to a concatenati.n of nontri.i.l pri.e codes or languages. A code i. pri.e i. i. cannot be decomposed i.to at least two nontri.i.l codes as the same for the languages. i. the paper, a li.ear ti.e algori.hm i. desi.ned, whi.h fi.ds the pri.e decomposi.i.n. i. codes or fi.i.e languages are presented as gi.en by i.s mi.i.al determi.i.ti. automaton, then from the poi.t of vi.w of abstract algebra and graph theory, thi. automaton has speci.l properti.s. The study was conducted usi.g system for computati.nal Di.crete Algebra GAP. .

关键词： Fi.i.e Languages Mi.i.al Determi.i.ti. Automata Concatenati.n Codes Graph of Automaton Free Algebra

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The Ti.i.g of Pri.ary Neurosurgi.al Repai. and Wound-Si.e i.fecti.n i. Chi.dren wi.h Myelomeni.gocele

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Open Journal of Modern Neurosurgery 2024年第2期14卷 137-148页

作者： Joseph O. Obande Paul T. Bi.rus Eli.abeth i. Obande Di.i.i.n of Neurosurgery Department of Surgery University of Abuja Teaching Hospital Abuja Nigeria Post-Basi. School of Cri.i.al Care Nursi.g University of Abuja Teaching Hospital Abuja Nigeria

Background: The opti.al ti.e to closure of a newborn wi.h a myelomeni.gocele has been the focus of a number of evaluati.ns. The Ti.i.g of pri.ary surgery has recei.ed si.ni.i.ant attenti.n due to i.s relati.nshi. to repai.-si.e i.fecti.n that can lead to i.creased morbi.i.y and prolonged hospi.al stays. i. i. on thi. basi. that recommendati.ns have uti.i.ed 48 - 72 hours post bi.th as i.eal ti.e of closure. Thi. i. not only prevent i.fecti.n at the si.e but also prevent ventri.uli.i. and neural structure damage. We therefore, hypothesi.ed an i.crease i. wound i.fecti.n rates i. those pati.nts wi.h delays i. myelomeni.gocele repai.. Methods: We retrospecti.ely revi.wed the records of 103 chi.dren wi.h myelomeni.gocele treated between 2016 and 2023. At di.charge the pati.nts were followed up at the post-operati.e cli.i. vi.i. 2 weeks later. Chi.dren were assi.ned to 1 of 2 groups, those who underwent pri.ary neurosurgi.al repai. wi.hi. 72 hours of deli.ery (Group 1) and those undergoi.g repai. after 72 hours (Group 2). We compared the i.fecti.n rates. Results: 103 chi.dren who underwent myelomeni.gocele repai. were i.enti.i.d, wi.h a medi.n ti.e from bi.th to treatment of 1 day. Ei.ht (7.8 %) pati.nts were noted to have post-repai. surgi.al si.e compli.ati.ns. There was no si.ni.i.ant di.ference i. rates of i.fecti.n between Group 1 and Group 2 repai. ti.es. The presence of i.fecti.n was associ.ted i.creased length of stay when compared to neonates wi.hout i.fecti.n. Conclusi.n: i. chi.dren wi.h myelomeni.gocele, the ti.i.g of pri.ary neurosurgi.al repai. appears not to have a si.ni.i.ant i.pact on surgi.al si.e i.fecti.n. Closure of the spi.al lesi.n wi.hi. the fi.st 72 hours of li.e may be more favorable for neural damage preventi.n. These results suggest that early myelomeni.gocele repai. may not i.part si.ni.i.antly on the rate of wound-si.e i.fecti.n.

关键词： Spi.a Bi.i.a Surgi.al Ti.i.g Exci.i.n and Repai. Surgi.al Si.e i.fecti.n Myelomeni.gocele

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Modeli.g of Total Di.solved Soli.s (TDS) and Sodi.m Absorpti.n Rati. (SAR) i. the Edwards-Tri.i.y Plateau and Ogallala Aqui.ers i. the Mi.land-Odessa Regi.n Usi.g Random Forest Regressi.n and eXtreme Gradi.nt Boosti.g

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Journal of Geosci.nce and Envi.onment Protecti.n 2024年第5期12卷 218-241页

作者： Azuka i. Udeh Osayamen J. i.arhi.gbe Erepamo J. Omi.ti.i Department of Geosci.nce University of Texas Permian Basin Odessa Texas USA Department of Geology University of Pretoria Pretoria South Africa

Effi.i.nt water quali.y moni.ori.g and ensuri.g the safety of dri.ki.g water by government agenci.s i. areas where the resource i. constantly depleted due to anthropogeni. or natural factors cannot be overemphasi.ed. The above statement holds for West Texas, Mi.land, and Odessa Preci.ely. Two machi.e learni.g regressi.n algori.hms (Random Forest and XGBoost) were employed to develop models for the predi.ti.n of total di.solved soli.s (TDS) and sodi.m absorpti.n rati. (SAR) for effi.i.nt water quali.y moni.ori.g of two vi.al aqui.ers: Edward-Tri.i.y (plateau), and Ogallala aqui.ers. These two aqui.ers have contri.uted i.mensely to provi.i.g water for di.ferent uses rangi.g from domesti., agri.ultural, i.dustri.l, etc. The data was obtai.ed from the Texas Water Development Board (TWDB). The XGBoost and Random Forest models used i. thi. study gave an accurate predi.ti.n of observed data (TDS and SAR) for both the Edward-Tri.i.y (plateau) and Ogallala aqui.ers wi.h the R2 values consi.tently greater than 0.83. The Random Forest model gave a better predi.ti.n of TDS and SAR concentrati.n wi.h an average R, MAE, RMSE and MSE of 0.977, 0.015, 0.029 and 0.00, respecti.ely. For the XGBoost, an average R, MAE, RMSE, and MSE of 0.953, 0.016, 0.037 and 0.00, respecti.ely, were achi.ved. The overall performance of the models produced was i.pressi.e. From thi. study, we can clearly understand that Random Forest and XGBoost are appropri.te for water quali.y predi.ti.n and moni.ori.g i. an area of hi.h hydrocarbon acti.i.i.s li.e Mi.land and Odessa and West Texas at large.

关键词： Water Quali.y Predi.ti.n Predi.ti.e Modeli.g Aqui.ers Machi.e Learni.g Regressi.n eXtreme Gradi.nt Boosti.g

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On the “Oni.n Husk” Algori.hm for Approxi.ate Soluti.n of the Traveli.g Salesman Problem

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Journal of Appli.d Mathemati.s and Physi.s 2024年第4期12卷 1557-1570页

作者： Mi.hai. E. Abramyan Ni.olai.i. Krai.i.kov Bori. F. Melni.ov Faculty of Computati.nal Mathemati.s and Cyberneti.s Shenzhen MSU-BIT University Shenzhen China Department of Algebra and Di.crete Mathemati.s Southern Federal University Rostov-on-Don Russian Federation

The paper descri.es some i.plementati.n aspects of an algori.hm for approxi.ate soluti.n of the traveli.g salesman problem based on the constructi.n of convex closed contours on the i.i.i.l set of poi.ts (“ci.i.s”) and thei. subsequent combi.ati.n i.to a closed path (the so-called contour algori.hm or “oni.n husk” algori.hm). A number of heuri.ti.s related to the di.ferent stages of the algori.hm are consi.ered, and vari.us vari.nts of the algori.hm based on these heuri.ti.s are analyzed. Sets of randomly generated poi.ts of di.ferent si.es (from 4 to 90 and from 500 to 10,000) were used to test the algori.hms. The numeri.al results obtai.ed are compared wi.h the results of two well-known combi.atori.l opti.i.ati.n algori.hms, namely the algori.hm based on the branch and bound method and the si.ulated anneali.g algori.hm. .

关键词： Branch and Bound Method Contour Algori.hm “Oni.n Husk” Algori.hm Si.ulated Anneali.g Method Traveli.g Salesman Problem

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