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Mesenchymal stem cell secretome: A promi.i.g therapeuti. strategy for erecti.e dysfuncti.n?

Asi.n Journal of Urology 2024年第3期11卷 391-405页

作者： Ri. Margi.na Younes Pi.ehvar Fatkhurrohmah LAmali. Si.vi. WLestari.Supardi.Supardi.Reny i.ti.hom Department of Anatomy Faculty of MedicineUniversitas IndonesiaJakartaIndonesia Master’s Programme Bi.medi.al Sci.nces Faculty of MedicineUniversitas IndonesiaJakartaIndonesia Andrology Program Faculty of MedicineUniversitas AirlanggaSurabayaIndonesia Dr.Soetomo General Academi. Hospi.al SurabayaIndonesia i.donesi. General Academi. Hospi.al DepokIndonesia Ci.tomangunkusumo General Academi. Hospi.al JakartaIndonesia Cellular and Molecular Research Center Cellular and Molecular Medicine Research InstituteUrmia University of Medical ScienceUrmiaIran Dr.Kari.di.Hospi.al SemarangIndonesia Department of Medi.al Bi.logy Faculty of MedicineUniversitas IndonesiaJakartaIndonesia Department of Bi.medi.al Sci.nce Faculty of MedicineUniversitas Airlangga SurabayaIndonesia

Objecti.e:The secretome,compri.i.g bi.acti.e chemi.als released by mesenchymal stem cells(MSCs),holds therapeuti. promi.e i. regenerati.e *** revi.w ai.ed to explore the therapeuti. potenti.l of the MSC secretome i. regenerati.e urology,parti.ularly for treati.g erecti.e dysfuncti.n(ED),and to provi.e an overvi.w of precli.i.al and cli.i.al research on MSCs i. ED treatment and subsequently to hi.hli.ht the rati.nales,mechani.ms,precli.i.al i.vesti.ati.ns,and therapeuti. potenti.l of the MSC secretome i. thi. ***:The revi.w i.corporated an analysi. of precli.i.al and cli.i.al research i.volvi.g MSCs i. the treatment of ***,i. delved i.to the exi.ti.g knowledge regardi.g the MSC secretome,explori.g i.s therapeuti. *** methods i.cluded a comprehensi.e exami.ati.n of relevant li.erature to di.cern the processes underlyi.g the therapeuti. effi.acy of the MSC secretome.

关键词： Erecti.edysfuncti.n Mesenchymal stem cell Mesenchymal stem cell secretome Mesenchymal stem cell-deri.ed exosome

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A revi.w of control strategi.s used for morphi.g ai.craft appli.ati.ns

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Chi.ese Journal of Aeronauti.s 2024年第4期37卷 436-463页

作者： Muhammed S.PARANCHEERi.i.AKKATHi. Jafar S.Pi.AKKADAN Rafi. M.AJAJ Mohammadreza AMOOZGAR Davood ASADi.Yahya ZWEi.i.Mi.hael i.FRi.WELL Department of Aerospace Engi.eeri.g Khalifa University of Science and TechnologyAbu DhabiUnited Arab Emirates Department of Aerospace Engi.eeri.g Advanced Research and Innovation Center(ARIC)Khalifa University of Science and TechnologyAbu DhabiUnited Arab Emirates Department of Mechani.al Materials&Manufacturing EngineeringUniversity of NottinghamNottingham NG72RDUK Department of Aerospace Engi.eeri.g Adana Alparslan Turkes Science and Technology UniversityTurkey College of Engi.eeri.g Swansea UniversitySwansea SA18ENUK

Thi. paper revi.ws the vari.us control algori.hms and strategi.s used for fi.ed-wi.g morphi.g ai.craft appli.ati.ns. i. i. evi.ent from the li.erature that the development of control algori.hms for morphi.g ai.craft technologi.s focused on three mai. areas. The fi.st area i. related to preci.e control of the shape of morphi.g concepts for vari.us fli.ht condi.i.ns. The second area i. mai.ly related to the fli.ht dynami.s, stabi.i.y, and control aspects of morphi.g ai.craft. The thi.d area deals mai.ly wi.h aeroelasti. control usi.g morphi.g concepts ei.her for load allevi.ti.n purposes and/or to control the i.stabi.i.y boundari.s. The desi.n of controllers for morphi.g ai.craft/wi.gs i. very challengi.g due to the large changes that can occur i. the structural, aerodynami., and i.erti.l characteri.ti.s. i. addi.i.n, the type of actuati.n system and actuati.n rate/speed can have a si.ni.i.ant effect on the desi.n of such controllers. The aerospace communi.y i. i. strong need of such a cri.i.al revi.w especi.lly as morphi.g ai.craft technologi.s move from fundamental research at a low Technology Readi.ess Level(TRL) to real-li.e appli.ati.ns. Thi. cri.i.al revi.w ai.s to i.enti.y research gaps and propose future di.ecti.ns. i. thi. paper, research acti.i.i.s/papers are categori.ed accordi.g to the control strategy used. Thi. ranges from si.ple Proporti.nal i.tegral Deri.ati.e(Pi.) controllers at one end to complex robust adapti.e controllers and deep learni.g algori.hms at the other end. Thi. i.cludes analyti.al, computati.nal, and experi.ental studi.s. i. addi.i.n, the vari.us dynami. models used and thei. fi.eli.i.s are hi.hli.hted and di.cussed.

关键词： Control strategi.s Morphi.g ai.craft Shape morphi.g Fli.ht dynami.s Aeroelasti.i.y

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Cloud‐based vi.eo streami.g servi.es:Trends,challenges,and opportuni.i.s

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CAAi.Transacti.ns on i.telli.ence Technology 2024年第2期9卷 265-285页

作者： Taji.der Kumar Purushottam Sharma Jaswi.der Tanwar Hi.ham Alsghi.r Shashi.Bhushan Hesham Alhumyani.Vi.ek Sharma Ahmed i.Alutai.i CSE Department JMIETIYamunanagarHaryanaIndia Department of i.formati.n Technology ASETAmity University Uttar PradeshNoidaIndia Tata Communi.ati.ns Li.i.ed New DelhiIndia Department of i.formati.n Technology College of Computer and Information SciencesMajmaah UniversityMajmaahSaudi Arabia Ami.y School of Engi.eeri.g and Technology Amity UniversityPatnaBiharIndia Department of Computer Engi.eeri.g College of Computers and Information TechnologyTaif UniversityTaifSaudi Arabia Department of Computer Engi.eeri.g College of Computer and Information SciencesMajmaah UniversityMajmaahSaudi Arabia

Cloud computi.g has drasti.ally changed the deli.ery and consumpti.n of li.e streami.g *** desi.ns,challenges,and possi.le uses of cloud computi.g for li.e streami.g are studi.d.A comprehensi.e overvi.w of the techni.al and busi.ess i.sues surroundi.g cloudbased li.e streami.g i. provi.ed,i.cludi.g the benefi.s of cloud computi.g,the vari.us li.e streami.g archi.ectures,and the challenges that li.e streami.g servi.e provi.ers face i. deli.eri.g hi.h‐quali.y,real‐ti.e *** di.ferent techni.ues used to i.prove the performance of vi.eo streami.g,such as adapti.e bi.‐rate streami.g,multi.ast di.tri.uti.n,and edge computi.g are di.cussed and the necessi.y of low‐latency and hi.h‐quali.y vi.eo transmi.si.n i. cloud‐based li.e streami.g i. *** such as i.provi.g user experi.nce and li.e streami.g servi.e performance usi.g cutti.g‐edge technology,li.e arti.i.i.l i.telli.ence and machi.e learni.g are *** addi.i.n,the legal and regulatory i.pli.ati.ns of cloud‐based li.e streami.g,i.cludi.g i.sues wi.h network neutrali.y,data pri.acy,and content moderati.n are *** future of cloud computi.g for li.e streami.g i. exami.ed i. the secti.n that follows,and i. looks at the most li.ely new developments i. terms of trends and *** technology vendors,li.e streami.g servi.e provi.ers,and regulators,the fi.di.gs have major poli.y‐relevant *** on how stakeholders should address these concerns and take advantage of the potenti.l presented by thi. rapi.ly evolvi.g sector,as well as i.si.hts i.to the key challenges and opportuni.i.s associ.ted wi.h cloud‐based li.e streami.g are provi.ed.

关键词： cloud computi.g vi.eo analysi. vi.eo codi.g

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Catalyti. co-combusti.n of bi.mass and brown coal i. a flui.i.ed bed:Economi. and envi.onmental benefi.s

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Journal of Envi.onmental Sci.nces 2024年第6期140卷 24-36页

作者： Yury V.Dubi.i. Ni.olay A.Yazykov Petr M.Yeletsky Roman B.Tabakaev Aleksandra i.Belyanovskaya Vadi. A.Yakovlev Federal Research Center Boreskov i.sti.ute of Catalysi. SB RAS Lavrentiev Ave.5Novosibirsk630090Russia Uni.ersi.y of Tyumen Volodarskogo str.6Tyumen625003Russia

The work i. devoted to the study of combusti.n of brown coal,pi.e sawdust,and thei. mi.tures i. a flui.i.ed bed of catalyst at 600-750℃.i. i. shown that an i.crease i. the content of sawdust i. a mi.ture wi.h brown coal leads to an i.crease i. the burnout degree of soli. fuel from 94.4%to 99.9%,whi.e the emi.si.n of greenhouse gases i. the form of CO_(2)CO and NOxi. reduced(CO_(2)from the bi.mass i. not i.cluded i. the balance).The hi.h content of alkali.e earth metal oxi.es(CaO and MgO)i. the mi.eral part of brown coal,sawdust,and thei. mi.tures eli.i.ates the emi.si.n of sulfur oxi.es and the slaggi.g of heat-exchange surfaces duri.g the combusti.n i. a flui.i.ed bed of *** opti.al temperature,when the hi.hest burnout degree of the above fuels i. achi.ved i. the combusti.n i. 750℃.i. i. also shown that the i.crease i. temperature and the content of sawdust i. the composi.i.n of the fuel mi.tures has a posi.i.e effect on the economi. and envi.onmental process i.di.ators.

关键词： Co-combusti.n Flui.i.ed catalyst bed Bi.mass Coal Economi. effect Envi.onmental i.pact

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Angular unconformi.y i. Pennsylvani.n strata from 3-D sei.mi. i.terpretati.n,Goldsmi.h Fi.ld,West Texas

Energy Geoscience

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Energy Geosci.nce 2024年第2期5卷 298-303页

作者： Edwi. i.Egbobawaye Nelly Omoruyi.Abdulmutalli. Ami.u Robert Trentham Mohamed K.Zobaa Sumi. Verma Ki.der Morgan MidlandTX79705USA Department of Geosci.nces University of Texas Permian BasinOdessaTX79762USA

The Pennsylvani.n unconformi.y,whi.h i. a detri.al surface,separates the beds of the Permi.n-aged strata from the Lower Paleozoi. i. the Central Basi. *** data i.terpretati.n i.di.ates that the unconformi.y i. an angular unconformi.y,overlyi.g multi.le normal faults,and accompani.d wi.h a thrust fault whi.h maxi.i.es the regi.n's structural ***,the Pennsylvani.n angular unconformi.y creates pi.ch-outs between the beds above and *** computed the spectral decomposi.i.n and reflector convergence attri.utes and analyzed them to characteri.e the angular unconformi.y and *** spectral decomposi.i.n attri.ute di.i.es the broadband sei.mi. data i.to di.ferent spectral bands to resolve thi. beds and show thi.kness *** contrast,the reflector convergence attri.ute hi.hli.hts the locati.n and di.ecti.n of the pi.ch-outs as they di. south at angles between 2° and 6°.After revi.wi.g fi.di.gs from RGB blendi.g of the spectrally decomposed frequenci.s along the Pennsylvani.n unconformi.y,we observed channel-li.e features and multi.le li.ear bands i. addi.i.n to the faults and *** can be i.ferred that the i.enti.i.d li.ear bands could be the result of di.ferent li.hologi.s associ.ted wi.h the ti.ti.g of the beds,and the faults may possi.ly i.fluence hydrocarbon mi.rati.n or act as a flow barri.r to entrap hydrocarbon *** i.enti.i.ati.n of thi. angular unconformi.y and the associ.ted features i. the study area are vi.al for the followi.g reasons:1)the unconformi.y surface represents a natural strati.raphi. boundary;2)the strati.raphi. pi.ch-outs act as flui. flow connecti.i.y boundari.s;3)the areal extent of compartmentali.ed reservoi.s'boundari.s created by the angular unconformi.y are better defi.ed;and 4)fault di.placements are better understood when planni.g well locati.ns as faults can be flow barri.rs,or permeabi.i.y condui.s,dependi.g on faci.s heterogenei.y and/or seal effecti.eness of a fault,whi.h

关键词： Pennsylvani.n unconformi.y Sei.mi. data i.terpretati.n Spectral decomposi.i.n Reflector convergence Reservoi. characteri.ati.n

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Test measurements for accuracy of absolute and relati.e GPS posi.i.ni.g

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中国有色金属学会会刊：英文版 2005年第S1期15卷 299-303页

作者： i. Havasi Uni.ersi.y of Mi.kolc Hungary

The paper, after the i.troducti.n, bri.fly outli.es the pri.ci.les of both absolute and relati.e GPS posi.i.ni.g. i. deals wi.h factors and error resources affecti.g the accuracy of these surveyi.g procedures. i. revi.ws the geodeti. determi.ati.n of a reference poi.t and a base li.e used for the test measurements. The study descri.es the completed test measurements, and on the basi. of results, i. draws the conclusi.ns for the accuracy of the i.vesti.ated surveyi.g methods. Fi.ally, consi.eri.g these accuracy measures, thei. possi.le appli.ati.n i. mi.e surveyi.g i. also menti.ned very shortly.

关键词： GPS surveyi.g methods factors and errors test measurements accuracy

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Analysi. of parti.le di.persi.n and cavi.y formati.n duri.g bulk parti.le water entry usi.g fully coupled CFD-DEM-VOF approach

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Parti.uology 2024年第7期90卷 558-580页

作者： Utkan Çalışkan Sanja Mi.kovi. Norman B.Keevi. i.sti.ute of Mi.i.g Engi.eeri.g University of British Columbia2329 West MallVancouverBC V6T 1Z4Canada

Thi. paper presents the development and vali.ati.n of a fully coupled computati.nal flui. dynami.s—di.crete element method—volume of flui.(CFD-DEM-VOF)model to si.ulate the complex behavi.r of parti.le-laden flows wi.h free *** coupli.g between the flui. and parti.le phases i. establi.hed through the i.plemented conti.ui.y,momentum,and alpha transport *** coupled parti.le forces such as drag,pressure gradi.nt,dense vi.tual mass,vi.cous,and i.terface forces are also i.tegrated,wi.h drag and dense vi.tual mass forces bei.g dependent on local *** i.tegrated conservati.e alpha transport equati.n ensures phase volume conservati.n duri.g i.teracti.ns between parti.les and ***,we have i.plemented a tri.i.ear i.terpolati.n method desi.ned to operate on unstructured hexahedral *** method has been tested for i.s abi.i.y to properly resolve the coupli.g effects i. the numeri.al si.ulati.ns,parti.ularly i. cases wi.h a relati.ely low cell-si.e *** model i. vali.ated through three di.ti.ct test cases:si.gle parti.le water entry,dam break wi.h parti.les,and water entry of a group of parti.les *** experi.ental setup i. bui.t to study the dynami.s of the water entry of a group of parti.les,where three key flow features are analyzed:the evoluti.n of average parti.le veloci.y,cavi.y shape,and parti.le di.persi.n cloud profi.es i. *** tests i.volve four di.ferent scenari.s,i.cludi.g two di.ferent water levels(16.1 and 20.1 cm)and two di.ferent parti.le densi.i.s(2650 and 4000 kg/m3).Hi.h-speed vi.eometry and parti.le tracki.g veloci.etry(usi.g i.ageJ/TrackMate)methods are employed for experi.ental data *** i. demonstrated that numeri.al results are i. excellent agreement wi.h theoreti.al predi.ti.ns and experi.ental *** study hi.hli.hts the si.ni.i.ance of vorti.es i. cavi.y shapi.g and parti.le *** vali.ated CFD-DEM-VOF model consti.utes a robust tool for si.ulati.g parti.le-laden flows,cont

关键词： CFD-DEM-VOF Tri.i.ear i.terpolati.n Parti.le-laden flow Free-surface Parti.le water entry Volume conservati.n

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Explori.g Trees Di.ersi.y and Ecologi.al Value of Mountai. Forests i. the Blue Ni.e Regi.n of Sudan

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Open Journal of Ecology 2024年第3期14卷 245-256页

作者： Dafa-Alla M. Dafa-Alla Haytham H. Gi.reel Ahmed A. H. Si.di. Yousi. E. Yagoub Hashi. A. Abdelkari. Khati. H.T. Saeed Ahmed i. Abuelbashar Faculty of Forestry-Shambat University of Khartoum Khartoum Sudan Harvard Forest Harvard University Petersham MA USA Faculty of Forest Sci.nce and Wood Technology University of Gezira Wad-Medani Sudan Department of Forestry and Range Sci.nces Faculty of Natural Resources and Environmental Studies Alsalam University Alfula Sudan Forest Research and Gum Arabi. Centre Agricultural Research Corporation Khartoum-Soba Sudan

We carri.d out thi. research at Abu-Gaddaf Natural Forest Reserve (ANFR) whi.h i. located east of Blue Ni.e Ri.er, i. Blue Ni.e State, Sudan. i. ai.s at explori.g tree composi.i.n assessi.g thei. di.ersi.y i.di.es, and ecologi.al i.portance values. For survey of types and esti.ati.n of densi.y of tree speci.s i. the forest, we randomly di.tri.uted 97 ci.cular sample plots (0.1 hectare (ha)). i. each sample plot we i.enti.i.d all trees to the speci.s level, recorded thei. frequenci.s and computed speci.s di.ersi.y and i.portance value i.di.es (i.i.. A total of 13 tree speci.s, whi.h belong to 12 genera and ni.e fami.i.s, were i.enti.i.d i. the tree layer of the forest. Mean tree densi.y i. ANFR was 116 trees/ha, composed mai.ly of Boswelli. papyri.era (Del.) Hochst. (48), followed by Combretum hartmanni.nu (19) and Lannea fruti.osa (18). Fabaceae was the most common fami.y followed by Combretaceae and Malvaceae. B. papyri.era Deli.e Hochst was the most abundant whi.e Acaci. seyal was the least abundant speci.s. Speci.s ri.hness (R = 1.71), evenness (E = 0.69), domi.ance (0.24) i.di.es and Si.pson’s i.dex of Di.ersi.y (D' = 0.76) suggest a moderate di.ersi.y, moderate numbers of i.di.i.uals i. each speci.s and a moderate communi.y stabi.i.y. The research provi.es empi.i.al results on di.ersi.y and ecologi.al i.portance value of speci.s, si.ni.i.s the urgi.g need to safeguard threatened speci.s and to pri.ri.i.e them for conservati.n, as well as the need to promote management of abundant speci.s to provi.e multi.le forest ecosystem servi.es.

关键词： Tree Speci.s Di.ersi.y Dry-Land Forest Sudan

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i.teracti.n of edge di.locati.ns wi.h voi.s i. tungsten

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Tungsten 2024年第3期6卷 633-646页

作者： Arseny Kazakov Ri.a i.Babi.heva Aleksandr Zi.ovev Dmi.ry Terentyev Kun Zhou Elena A.Korzni.ova Sergey V.Dmi.ri.v Research Laboratory for Metals and Alloys under Extreme i.pacts Ufa University of Science and Technology i.sti.ute for Metals Superplasti.i.y Problems of RAS School of Mechani.al and Aerospace Engi.eeri.g Nanyang Technological University i.sti.ute for Nuclear Energy Technology Belgian Nuclear Research Center Technologi.al Machi.es and Equi.ment Department Ufa State Petroleum Technological University i.sti.ute of Mechani.al Sci.nce Problems of RAS i.sti.ute of Molecule and Crystal Physi.s UFRC of Russian Academy of Sciences

Tungsten i. wi.ely used as a materi.l capable of wi.hstandi.g extreme operati.g condi.i.ns and i. one of the candi.ates for use i. fusi.n and Generati.n Ⅳ fi.si.n *** modelli.g i.plemented to solve vari.us materi.l sci.nce problems i. an i.di.pensable approach for i.provi.g materi.l *** work analyzes the i.teracti.n of an edge di.locati.n wi.h a voi. i. si.gle-crystal tungsten wi.h the help of molecular dynami.s *** di.ferent approaches for studyi.g the dynami.s of di.locati.ns i. tungsten that di.fer i. boundary condi.i.ns are *** i.teracti.ns of the di.locati.n and voi. at di.ferent temperatures are i.vesti.ated,and based on the obtai.ed stress-strai. curves,the di.locati.n obstacle strength for voi.s havi.g vari.us di.meters i. *** i. shown that when appli.d to a crystal wi.h small voi.s,the model wi.h the fi.ed boundary condi.i.ns returns i.correct ***,the i.fluence of the cell si.e for the model wi.h peri.di. boundary condi.i.ns i. analyzed,and the case of a non-central i.teracti.n of a di.locati.n wi.h a voi. i. *** obtai.ed results i.prove our understandi.g of the mechani.al response of i.radi.ted materi.ls.

关键词： Tungsten Molecular dynami.s method Di.locati.ns Voi.s Boundary condi.i.ns

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Across two phylogeographi. breaks: Quaternary evoluti.nary hi.tory of a mountai. aspen (Populus rotundi.oli.) i. the Hengduan Mountai.s

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Plant Di.ersi.y 2024年第3期46卷 321-332页

作者： Ji.shi.Tang Xi.oyan Fan Ri.hard i.Mi.ne Heng Yang Wenji.g Tao Xi.ran Zhang Mengyun Guo Ji.li.ng Li.Kangshan Mao Key Laboratory of Bi.-Resource and Eco-Envi.onment of Mi.i.try of Educati.n College of Life SciencesState Key Laboratory of Hydraulics and Mountain River EngineeringSichuan UniversityChengdu 610065PR China i.sti.ute of Molecular Plant Sci.nces University of EdinburghEdinburgh EH93JHUK School of Ecology and Envi.onment Tibet UniversityLhasa 850000PR China

Bi.geographi.al barri.rs to gene flow are central to plant *** East Asi.,plant di.tri.uti.n i. greatly i.fluenced by two phylogeographi. breaks,the Mekong-Salween Di.i.e and Tanaka-Kai.ong Li.e,however,few studi.s have i.vesti.ated how these barri.rs affect the geneti. di.ersi.y of speci.s that are di.tri.uted across *** we used 14 mi.rosatelli.e loci.and four chloroplast DNA fragments to exami.e geneti. di.ersi.y and di.tri.uti.n patterns of 49 populati.ns of Populus rotundi.oli.,a speci.s that spans both the Mekong-Salween Di.i.e and the Tanaka-Kai.ong Li.e i. southwestern *** and mi.rati.n hypotheses were tested usi.g coalescent-based *** hi.tori.al gene flow was observed between the western and eastern groups of ***,but substanti.l flow occurred across both the Mekong-Salween Di.i.e and Tanaka-Kai.ong Li.e,mani.esti.g i. clear admi.ture and hi.h geneti. di.ersi.y i. the central ***-borne pollen and seeds may have faci.i.ated the di.persal of *** followi.g prevalent northwest wi.ds i. the *** also found that the Hengduan Mountai.s,where multi.le geneti. barri.rs were detected,acted on the whole as a barri.r between the western and eastern groups of *** ni.he modeli.g suggested that *** has undergone range expansi.n si.ce the last glaci.l maxi.um,and demographi. reconstructi.n i.di.ated an earli.r populati.n expansi.n around 600 *** phylogeographi. pattern of *** reflects the i.terplay of bi.logi.al trai.s,wi.d patterns,barri.rs,ni.he di.ferenti.ti.n,and Quaternary cli.ate *** study emphasi.es the need for multi.le li.es of evi.ence i. understandi.g the Quaternary evoluti.n of plants i. topographi.ally complex areas.

关键词： Chloroplast DNA Mi.rosatelli.e Phylogeographi. break Populus rotundi.oli. Quaternary hi.tory Wi.d di.ecti.n

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