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Soli. Parti.le Erosi.n Behavi.ur of Ti. Coati.g on Ai.i.4140 Steel

Journal of Surface Engi.eered Materi.ls and Advanced Technology 2014年第1期4卷 1-8页

作者： J. R. Laguna-Camacho J. E. Escalante-Martínez R. Cruz-vi.enci. J. v. Méndez-Méndez i. arzate-vázquez i. Hernández-Romero M. vi.e-Torres Centro de Nanoci.nci.s y Mi.ro y Nanotecnologías IPN Mexico City México Faculty of Chemi.al Engi.eeri.g Universidad Veracruzana Poza Rica de Hidalgo Veracruz México Faculty of Electri. and Mechani.al Engi.eeri.g Universidad Veracruzana Poza Rica de Hidalgo Veracruz México i.sti.uto Poli.écni.o Naci.nal SEPI ESIME Unidad Profesional “Adolfo López Mateos” Tribology Group Mechanical Engineering Department Mexico City México

i. thi. study, the performance agai.st erosi.e wear of PvD Ti. (ti.ani.m ni.ri.e) coati.g was evaluated usi.g an erosi.n test ri. si.i.ar to that descri.ed i. the standard ASTM G76-95. Thi. coati.g normally has vari.us i.dustri.l appli.ati.ns such as tappi.g, dri.li.g, dry machi.i.g and punchi.g. Angular si.i.on carbi.e (Si.) was used as an abrasi.e parti.le wi.h a grai. si.e of 350-450 μm. Erosi.n tests were carri.d out usi.g di.ferent i.ci.ent angles, 30°, 45°, 60° and 90° wi.h a parti.le veloci.y of 24 ± 2 m/s, an abrasi.e flow rate of 0.7 ± 0.5 g/mi., and the test temperature was between 35°C and 40°C. The parti.le veloci.y and the abrasi.e flow rate were low i. all of the tests to reduce the i.teracti.n between the i.ci.ent and the reboundi.g parti.les i. the system. The surfaces were exami.ed wi.h a scanni.g electron mi.roscope (SEM) to characteri.e the erosi.e damage. The wear mechani.ms i.enti.i.d were bri.tle fracture characteri.ed by radi.l cracks on the surface by multi.le i.pact and a few pi.s at 30°, whi.e a few cracks and the formati.n of craters i. random posi.i.ns were observed at angles near or at 90°. Elli.ti.al scars were observed at 30° and 45°, whi.h are a characteri.ti. feature when the speci.ens are i.pacted at low-i.ci.ent angles (α ≤ 45°) whereas a roughly ci.cular scar was seen at 60° and 90°. i. addi.i.n, roughness vari.ti.ns were analyzed usi.g atomi. force mi.roscopy (AFM), before and after the erosi.n tests, and the results exhi.i.ed an i.crease i. the roughness as the Ti. samples were i.pacted at angles near or at 90°.

关键词： Erosi.n Wear PvD Ni.ri.e Coati.g Ti. Wear Mechani.ms

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Dendri.i. spi.e degenerati.n:a pri.ary mechani.m i. the agi.g process

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Neural Regenerati.n Research 2025年第6期20卷 1696-1698页

作者： Gonzalo Flores Leonardo Agui.ar-Hernández Fernado García-Dolores Humberto Ni.oli.i.Andrea Judi.h vázquez-Hernández Hi.am Tendi.la-Beltrán i.sti.uto de Fi.i.logía Benemérita Universidad Autónoma de Puebla(BUAP)PueblaMexico i.sti.uto de Ci.nci.s Forenses(i.Ci.O) Tribunal Superior de Justicia de la Ciudad de México(TSJCDMX).Mexico CityMexico i.sti.uto Naci.nal de Medi.i.a Genómi.a(i.MEGEN) Mexico CityMexico

Recent reports suggest that agi.g i. not solely a physi.logi.al process i. li.i.g bei.gs;i.stead, i. should be consi.ered a pathologi.al process or di.ease(Amori. et al., 2022). Consequently, thi. process i.volves a wi.e range of factors, spanni.g from geneti. to envi.onmental factors, and even i.cludes the gut mi.robi.me(GM)(Mayer et al., 2022). All these processes coi.ci.e at some poi.t i. the i.flammatory process, oxi.ati.e stress, and apoptosi., at di.ferent degrees i. vari.us organs and systems that consti.ute a li.i.g organi.m(Mayer et al., 2022;Agui.arHernández et al., 2023).

关键词： agi.g process stress

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Semanti. Segmentati.n of Lumbar vertebrae Usi.g Mei.eri.g U-Net(MU-Net)on Spi.e Magneti. Resonance i.ages

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Computer Modeli.g i. Engi.eeri.g & Sci.nces 2025年第1期142卷 733-757页

作者： Lakshmi.S v v Shi.oah Eli.abeth Darmanayagam Suni. Retmi. Raj Cyri. Department of Computer Sci.nce and Engi.eeri.g College of Engineering GuindyAnna UniversityChennai600025India Department of i.formati.n Technology Madras Institute of TechnologyAnna UniversityChrompetChennai600044India

Lower back pai. i. one of the most common medi.al problems i. the world and i. i. experi.nced by a huge percentage of people *** to i.s abi.i.y to produce a detai.ed vi.w of the soft ti.sues,i.cludi.g the spi.al cord,nerves,i.tervertebral di.cs,and vertebrae,Magneti. Resonance i.agi.g i. thought to be the most effecti.e method for i.agi.g the *** semanti. segmentati.n of vertebrae plays a major role i. the di.gnosti. process of lumbar *** i. di.fi.ult to semanti.ally parti.i.n the vertebrae i. Magneti. Resonance i.ages from the surroundi.g vari.ty of ti.sues,i.cludi.g muscles,li.aments,and i.tervertebral di.cs.U-Net i. a powerful deep-learni.g archi.ecture to handle the challenges of medi.al i.age analysi. tasks and achi.ves hi.h segmentati.n *** work proposes a modi.i.d U-Net archi.ecture namely MU-Net,consi.ti.g of the Mei.eri.g convoluti.nal layer that i.corporates the Mei.eri.g fi.ter to perform the semanti. segmentati.n of lumbar vertebrae L1 to L5 and sacral vertebra ***-colour mask i.ages were generated and used as ground truth for trai.i.g the *** work has been carri.d out on 1312 i.ages expanded from T1-wei.hted mi.-sagi.tal MRi.i.ages of 515 pati.nts i. the Lumbar Spi.e MRi.Dataset publi.ly avai.able from Mendeley *** proposed MU-Net model for the semanti. segmentati.n of the lumbar vertebrae gi.es better performance wi.h 98.79%of pi.el accuracy(PA),98.66%of di.e si.i.ari.y coeffi.i.nt(DSC),97.36%of Jaccard coeffi.i.nt,and 92.55%mean i.tersecti.n over Uni.n(mean i.U)metri.s usi.g the menti.ned dataset.

关键词： Computer ai.ed di.gnosi.(CAD) magneti. resonance i.agi.g(MRi. semanti. segmentati.n lumbar vertebrae deep learni.g U-Net model

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Hardness of Mn_2v_2O_7 thi. fi.ms and i.s i.fluenti.l factors

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i.ternati.nal Journal of Mi.erals,Metallurgy and Materi.ls 2015年第9期22卷 987-991页

作者： i. Aft i. Kari.er Department of Sci.nce Educati.n Faculty of Education Erciyes University Kayseri 38039 Turkey

Mn2v2O7 thi. fi.ms were deposi.ed onto amorphous glass substrates usi.g a chemi.al bath deposi.i.n method and di.ferent deposi.i.n ti.e. X-ray di.fracti.n （XRD） analysi. was used to defi.e the structure of the fi.ms. Thei. roughness, thi.kness, and surface properti.s were evaluated through atomi. force mi.roscopy （AFM）. The hardness of the fi.ms was measured usi.g a nanohardness tester The fi.m thi.kness, average grai. si.e, and roughness were posi.i.ely correlated wi.h each other. These three parameters were observed to i.crease wi.h the deposi.i.n ti.e. The fi.m thi.kness and average grai. si.e were i.versely correlated wi.h the hardness and rough- ness. i. addi.i.n, the number of crystalli.es per uni. area and the di.locati.n densi.y were observed to be posi.i.ely correlated wi.h the hardness and roughness. Thi. study was desi.ned to eluci.ate and formali.e the underlyi.g reasons for these relati.nshi.s.

关键词： manganese vanadate thi. fi.ms nanohardness i.fluenci.g factors

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Auti.m spectrum di.order:di.fi.ulti.s i. di.gnosi. and mi.roRNA bi.markers

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Neural Regenerati.n Research 2025年第10期20卷 2776-2786页

作者： Bri.get Marti.ez Phi.i. v.Peplow Department of Pharmacology University of Nevada-RenoRenoNVUSA Department of Medi.i.e University of Nevada-RenoRenoNVUSA Department of Anatomy University of OtagoDunedinNew Zealand

We performed a PubMed search for mi.roRNAs i. auti.m spectrum di.order that could serve as di.gnosti. bi.markers i. pati.nts and selected 17 arti.les publi.hed from January 2008 to December 2023,of whi.h 4 studi.s were performed wi.h whole blood,4 wi.h blood plasma,5 wi.h blood serum,1 wi.h serum neural cell adhesi.n molecule L1-captured extracellular vesi.les,1 wi.h blood cells,and 2 wi.h peri.heral blood mononuclear *** of the studi.s i.volved chi.dren and the study cohorts were largely *** of the studi.s had performed mi.roRNA sequenci.g or quanti.ati.e polymerase chai. reacti.n assays to measure mi.roRNA *** fi.e studi.s had used real-ti.e polymerase chai. reacti.n assay to vali.ate mi.roRNA expressi.n i. auti.m spectrum di.order subjects compared to *** mi.roRNAs that were vali.ated i. these studi.s may be consi.ered as potenti.l candi.ate bi.markers for auti.m spectrum di.order and i.clude mi.-500a-5p,-197-5p,-424-5p,-664a-3p,-365a-3p,-619-5p,-664a-3p,-3135a,-328-3p,and-500a-5p i. blood plasma and mi.-151a-3p,-181b-5p,-320a,-328,-433,-489,-572,-663a,-101-3p,-106b-5p,-19b-3p,-195-5p,and-130a-3p i. blood serum of chi.dren,and mi.-15b-5p and-6126 i. whole blood of *** i.portant li.i.ati.ns were i.enti.i.d i. the studi.s revi.wed,and need to be taken i.to account i. future *** studi.s are warranted wi.h chi.dren and adults havi.g di.ferent levels of auti.m spectrum di.order severi.y and consi.erati.n should be gi.en to usi.g ani.al models of auti.m spectrum di.order to i.vesti.ate the effects of suppressi.g or overexpressi.g speci.i. mi.roRNAs as a novel therapy.

关键词： auti.m spectrum di.order bi.marker blood cells blood plasma blood serum di.gnosi. mi.roRNA peri.heral blood mononuclear cells serum neural cell adhesi.n molecule L1-captured extracellular vesi.les whole blood

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Mi.roRNAs as potenti.l di.gnosti. bi.markers for bi.olar di.order

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Neural Regenerati.n Research 2025年第6期20卷 1681-1695页

Abnormal expressi.n of mi.roRNAs i. connected to brai. development and di.ease and could provi.e novel bi.markers for the di.gnosi. and prognosi. of bi.olar di.order. We performed a PubMed search for mi.roRNA bi.markers i. bi.olar di.order and found 18 ori.i.al research arti.les on studi.s performed wi.h human pati.nts and publi.hed from January 2011 to June 2023. These studi.s i.cluded mi.roRNA profi.i.g i. bloodand brai.-based materi.ls. From the studi.s that had vali.ated the preli.i.ary fi.di.gs,potenti.l candi.ate bi.markers for bi.olar di.order i. adults could be mi.-140-3p,-30d-5p,-330-5p,-378a-5p,-21-3p,-330-3p,-345-5p i. whole blood, mi.-19b-3p,-1180-3p,-125a-5p, let-7e-5p i. blood plasma, and mi.-7-5p,-23b-5p,-142-3p,-221-5p,-370-3p i. the blood serum. Two of the studi.s had i.vesti.ated the changes i. mi.roRNA expressi.n of pati.nts wi.h bi.olar di.order recei.i.g treatment. One showed a si.ni.i.ant i.crease i. plasma mi.-134 compared to baseli.e after 4 weeks of treatment whi.h i.cluded typi.al anti.sychoti.s, atypi.al anti.sychoti.s, and benzodi.zepi.es. The other study had assessed the effects of prescri.ed medi.ati.ns whi.h i.cluded neurotransmi.ter receptorsi.e bi.ders(drug class B) and sedati.es, hypnoti.s, anti.onvulsants, and analgesi.s(drug class C) on mi.roRNA results. The combi.ed effects of the two drug classes i.creased the si.ni.i.ance of the results for mi.-219 and-29c wi.h mi.-30e-3p and-526b* acqui.i.g si.ni.i.ance. Mi.roRNAs were tested to see i. they could serve as bi.markers of bi.olar di.order at di.ferent cli.i.al states of mani., depressi.n, and euthymi.. One study showed that upregulati.n i. whole blood of mi.-9-5p,-29a-3p,-106a-5p,-106b-5p,-107,-125a-3p,-125b-5p and of mi.-107,-125a-3p occurred i. mani. and euthymi. pati.nts compared to controls, respecti.ely, and that upregulati.n of mi.-106a-5p,-107 was found for mani. compared to euthymi. pati.nts. i. two other studi.s usi.g blood plasma,downregulati.n of mi.-134 was observed i

关键词： bi.marker bi.olar di.order blood leukocytes blood plasma blood plasma extracellular vesi.les/exosomes blood serum brai. ti.sue brai. ti.sue extracellular vesi.les/exosomes lymphoblastoi. cell li.es mi.roRNA neural progeni.or cells whole blood

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Mi.roRNAs as potenti.l bi.markers for di.gnosi. of post-traumati. stress di.order

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Neural Regenerati.n Research 2025年第7期20卷 1957-1970页

Post-traumati. stress di.order i. a mental di.order caused by exposure to severe traumati. li.e ***,there are no vali.ated bi.markers or laboratory tests that can di.ti.gui.h between trauma survi.ors wi.h and wi.hout post-traumati. stress *** addi.i.n,the heterogenei.y of cli.i.al presentati.ns of post-traumati. stress di.order and the overlap of symptoms wi.h other condi.i.ns can lead to mi.di.gnosi. and i.appropri.te *** suggests that thi. condi.i.n i. a multi.ystem di.order that affects many bi.logi.al systems,rai.i.g the possi.i.i.y that peri.heral markers of di.ease may be used to di.gnose post-traumati. stress *** performed a PubMed search for mi.roRNAs(mi.NAs)i. post-traumati. stress di.order(PTSD)that could serve as di.gnosti. bi.markers and found 18 ori.i.al research arti.les on studi.s performed wi.h human pati.nts and publi.hed January 2012 to December *** i.cluded four studi.s wi.h whole blood,seven wi.h peri.heral blood mononuclear cells,four wi.h plasma extracellular vesi.les/exosomes,and one wi.h serum *** of these studi.s had also used whole *** studi.s were excluded as they di. not i.volve mi.roRNA *** of the studi.s had collected samples from adult male veterans who had returned from deployment and been exposed to combat,and only two were from recently traumati.ed adult *** measuri.g mi.NA expressi.n levels,many of the studi.s had used mi.roarray mi.NA analysi.,mi.NA Seq analysi.,or NanoStri.g *** si. studi.s had used real ti.e polymerase chai. reacti.n assay to determi.e/vali.ate mi.NA expressi.n i. PTSD subjects compared to *** mi.NAs that were found/vali.ated i. these studi.s may be consi.ered as potenti.l candi.ate bi.markers for PTSD and i.clude mi.-3130-5p i. whole blood;mi.-193a-5p,-7113-5p,-125a,-181c,and-671-5p i. peri.heral blood mononuclear cells;mi.-10b-5p,-203a-3p,-4488,-502-3p,-874-3p,-5100,and-7641 i. plasma extracellular vesi.les/

关键词： bi.marker di.gnosi. mi.roRNA peri.heral blood mononuclear cells plasma extracellular vesi.les/exosomes post-traumati. stress di.order serum exosomes whole blood whole plasma

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An SPH Framework for Earthquake-i.duced Li.uefacti.n Hazard Assessment of Geotechni.al Structures

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Computer Modeli.g i. Engi.eeri.g & Sci.nces 2025年第1期142卷 251-277页

作者： Sourabh Mhaski.G.v.Ramana Department of Ci.i. Engi.eeri.g Indian Institute of Technology DelhiNew Delhi110016India

Earthquake-i.duced soi. li.uefacti.n poses si.ni.i.ant ri.ks to the stabi.i.y of geotechni.al structures *** understandi.g of the li.uefacti.n tri.geri.g,and the post-fai.ure large deformati.n behavi.ur i. essenti.l for desi.ni.g resi.i.nt *** present study develops a Smoothed Parti.le Hydrodynami.s(SPH)framework for earthquake-i.duced li.uefacti.n hazard assessment of geotechni.al *** coupled flowdeformati.n behavi.ur of soi.s subjected to cycli. loadi.g i. descri.ed usi.g the PM4Sand model i.plemented i. a three-phase,si.gle-layer SPH framework.A staggered di.creti.ati.n scheme based on the stress parti.le SPH approach i. adopted to mi.i.i.e numeri.al i.accuraci.s caused by zero-energy modes and tensi.e ***,non-reflecti.g boundary condi.i.ns for sei.mi. analysi. of semi.i.fi.i.e soi. domai.s usi.g the SPH method are *** numeri.al framework i. employed for the analysi. of cycli. di.ect si.ple shear test,sei.mi. analysi. of a level ground si.e,and li.uefacti.n-i.duced fai.ure of the Lower San Fernando *** agreement for li.uefacti.n tri.geri.g and post-fai.ure behavi.ur demonstrates that the SPH framework can be uti.i.ed to assess the effect of sei.mi. loadi.g on fi.ld-scale geotechni.al *** present study also serves as the basi. for future advancements of the SPH method for appli.ati.ns related to earthquake geotechni.al engi.eeri.g.

关键词： Earthquake sei.mi. li.uefacti.n stress parti.le PM4Sand smoothed parti.le hydrodynami.s(SPH)

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Unlocki.g hypoglycemi.–associ.ted brai. mi.rovascular dysfuncti.n:cri.i.al i.si.hts from proteomi. analysi.

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Neural Regenerati.n Research 2025年第6期20卷 1707-1708页

作者： Si.a S.v.P.Sakamuri.Ani. Sakamuri Department of Chemi.try Auburn University at MontgomeryMontgomeryALUSA vascular Bi.logy Center and Department of Medi.i.e Medical College of Georgia at Augusta UniversityAugustaGAUSA

Hypoglycemi.-a cri.i.al compli.ati.n li.ked to worsened brai. functi.n i. di.beti. subjects:Hypoglycemi. i. characteri.ed by a decli.e i. ci.culatory glucose levels below sta nda rd physi.logi.al *** hypoglycemi.,classi.i.d as level 1 hypoglycemi.,i. defi.ed by blood glucose levels below 70 mg/dL and can be effecti.ely addressed through carbohydrate *** hypoglycemi.,denoted by blood glucose levels less than 54 mg/dL,poses a li.e-threateni.g ri.k i. left *** wi.h type 1 and type 2 di.betes undergoi.g i.suli. treatment are parti.ularly suscepti.le to hypoglycemi. due to i.pai.ed counterregulatory mechani.ms.

关键词： i.pai.ed i.take cri.i.al

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Corti.al hem si.nali.g center: functi.ns, development, and potenti.l i.pli.ati.ns for evoluti.n and brai. di.orders

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Neural Regenerati.n Research 2025年第4期20卷 1079-1080页

作者： vi.tor v.Chi.hi.ov i.or Y.i.kusnykh Department of Anatomy and Neurobi.logy University of Tennessee Health Science CenterMemphisTNUSA

Development of the telencephalon reli.s upon several si.nali.g centers-locali.ed cellular populati.ns that supply secreted factors to pattern the corti.al *** such si.nali.g center i. the corti.al hem,whi.h ari.es duri.g embryoni. development at the telencephali. dorsal mi.li.e,adjacent to the choroi. plexus and hi.pocampal pri.ordi.m(Fi.ure 1A).Whi.e the corti.al hem has also been descri.ed i. repti.es and bi.ds,most of our knowledge about the developmental roles of the corti.al hem i. deri.ed from the analysi. i. *** corti.al hem produces several types of secreted molecules,i.cludi.g wi.gless-related i.tegrati.n si.e(Wnt)and bone morphogeneti.(Bmp)*** corti.al hem i. parti.ularly i.portant for the development of the hi.pocampus,whi.h i. i.volved i. learni.g and memory,and the neocortex,whi.h i. the most complex brai. regi.n that medi.tes multi.le types of behavi.r and hi.her cogni.i.e functi.ns(Mangale et al.,2008;Dal-valle-Anton and Borrell,2022).

关键词： epi.heli.m Fi.ure center

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