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Clinical profile and outcomes in very elderly patients with atrial fibrillation anticoagulated with rivaroxaban: data from the EMiR study

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Journal of Geriatric Cardiology 2024年第7期21卷 723-732页

作者： Francisco Marín Manuel Anguita Sánchez iñaki lekuona Marcelo Sanmartín Fernán-dez Vivencio Barrios Carlos Perez Muñoz Juan Cosín-Sales Alejandro iPérez Cabeza Vanesa Roldán Schilling Carles Rafols Priu Esteban Orenes-Piñero María Asunción Es-teve-Pastor Department of Cardiology Hospital Clínico Universitario Virgen de la ArrixacaIMIB-ArrixacaUniversity of MurciaCIBERCVMurciaSpain Department of Cardiology Hospital Reina Sofía CórdobaIMIBICUniversity of CordobaCIBERCVCórdobaSpain Hospital Galdakao-Usansolo BizkaiaSpain Department of Cardiology Hospital Uni-versitario Ramony CajalCIBERCVMadridSpain Department of Cardiology University Hospital Ramóny CajalAl-caláUniversityMadridSpain Medical Center La Capillita Sanlúcar de Barrameda.Private cardiology clinicJerez de la FronteraSpain Department of Cardiology Hospital Arnau de VilanovaValenciaSpain Department of Car-diology Virgen de la Victoria University HospitalCIBERCV.MalagaSpain Department of Haematology Hospital Clínico Universitario Virgen de la ArrixacaUniversity of MurciaMurciaSpain Department of Medical Affairs Bayer HispaniaBarcelonaSpain Department of Biochemistry and Molecular Biology-A University of MurciaMurciaSpain

Objectives To analyze the clinical profile,adequacy of treatment with rivaroxaban and outcomes in octogenarians with atrial fibrillation(AF),taking rivaroxaban in clinical *** Observational and non-interventional study that included AF adults recruited from 79 Spanish centers,anticoagulated with rivaroxaban ≥ 6 months before being *** were analyzed according to age(≥ 80 vs.ients,453(31.6%) were octogenarians at *** to younger patients,octogenarians had more comorbidities,higher CHA2DS2-VASc(4.5 ± 1.3 vs.3.0 ± 1.4;P ivaroxaban was adequately prescribed in 83.4% of patients,but more frequently in the younger population(71.1% vs.89.1%;P = 0.039).After a mean follow-up of 2.2 ± 0.6 years,annual rates of stroke + systemic embolism + transient ischemic attack,MACE,cardiovascular death and major bleeding were 1.03%,1.24%,1.03% and 1.75%,respectively,in octogenarian *** for progressive heart failure death and major bleeding,rates of outcomes in octogenarians were similar compared to younger *** octogenarians,the concomitant use of antiplatelet agents and non-severe dementia were independently associated with the development of ischemic stroke,whereas previous coronary revascularization and heart failure with MACE,and higher HAS-BLED score with major *** in clinical practice,around one third of patients taking rivaroxaban are *** patients have many comorbidities and a high thromboembolic *** that,rates of adverse events remain *** is adequately prescribed in the majority of octogenarians.

关键词： patients atrial bleeding

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Patients with cardiac disease: Changes observed through last decade in out-patient clinics

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World Journal of Cardiology 2013年第8期5卷 288-294页

作者： Alberto Cordero Vicente Bertomeu-Martínez Pilar Mazón Lorenzo Fácila Juan Cosín Vicente Bertomeu-González Moisés Rodriguez Eva Andrés Enrique Galve iaki lekuona Jose R González-Juanatey Cardiology Department Hospital Universitario de San Juan Cardiology Department Hospital General de Valencia Cardiology Department Hospital Arnau de Vilano-va Cardiology Department Hospital Complejo Universitario de Santiago de Compostela Research Unit Hospital Universitario 12 de Octu-bre Instituto de investigación 12 de Octubre (imas12) Ciber de Epidemiología y Salud Pública Cardiology Department Clínica Universitaria de Navarra Cardiology Department Hospital Valle Hebrón Cardiology Department Hospital Galdakano

AiM: To describe current profile of patients with cardio-vascular disease(CVD) and assessing changes through last ***: Comparison of patients with established CVD from two similar cross-sectional registries performed in 1999(n = 6194) and 2009(n = 4639).The types of CVD were coronary heart disease(CHD),heart failure(HF) and atrial fibrillation(AF).Patients were collected from outpatient *** were 80% cardiologist and 20% primary care *** antecedents,major diagnosis,blood test results and medical treatments were collected from all ***: An increase in all risk factors,except for smoking,was observed;a 54.4% relative increase in BP control was *** was the most prevalent CVD but HF and AF increased significantly,41.5% and 33.7%,respectively.A significant reduction in serum lipid levels was *** use of statins increased by 141.1% as did all cardiovascular ***,the use of angiotensin-renin system inhibitors in patients with HF,beta-blockers in CHD patients or oral anticoagulants in AF patients increased by 83.0%,80.3% and 156.0%,respectively(P iON: The prevalence of all cardiovascular risk factors has increased in patients with CVD through last *** and AF have experienced the largest increases.

关键词： Cardiovascular disease Trends Heart failure Coronary heart disease Atrial fibrillation

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