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Coarse to Fine: The Role of Severe Plastic Deformation in Advancing Titanium-Based Medical implants - A Comprehensive Review

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 295-306页

作者： Dragana R Mihajlović Bojan i Međo ivana Lj Cvijović-Alagić Veljko R Djokić Faculty of Technology and Metallurgy University of BelgradeKarnegijeva 411120 BelgradeSerbia Vinča institute of Nuclear Sci-ences-National institute of the Republic of Serbia University of Belgrade11001BeogradSerbia innovation Centre of the Faculty of Technology and Metallurgy Karnegijeva 411120 BelgradeSerbia

This paper describes severe plastic deformation(SPD)procedures,which are utilized to form an ultrafine-grained structure in metallic *** the SPD process,a solid material sample is subjected to very high loads without a significant change in sample *** the present work,the high-pressure torsion(HPT)process,as one of the SPD techniques,which achieves a high degree of deformation and ensures refinement of the microstructure,will be discussed in more *** that grain size control is accepted as a method to obtain materials with desired characteristics,an overview of the properties of ultrafine-grained titanium-based biomaterials to be used in medicine is ***,particular attention is dedicated to the influences of HPT process parameters,primarily hydrostatic pressure,and number of revolutions during torsion,on the grain size and physical and mechanical characteristics(modulus of elasticity,microhardness,and tensile properties),corrosion resistance,and biocompatibility of the titanium-based biomaterials.A review of the literature indicates that titanium-based materials obtained by the SPD process show improved mechanical and physical properties without losing biocompatibility and corrosion resistance,which suggests that these methods of obtaining implants are something that should be further developed in the future.

关键词： high-pressure torsion process ultrafine-grained titanium-based materials electrochemical anodization physical properties mechanical properties

Electro-tribological properties of diamond like carbon coatings

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Friction 2020年第2期8卷 451-461页

作者： iñigo BRACERAS iñigo iBÁNEZ Santiago DOMiNGUEZ-MEiSTER Xabier VELASCO Marta BRiZUELA iñaki GARMENDiA Tecnalia Research&innovation Mikeletegi Pasealekua 2Donostia-San Sebastian 20009Spain Mechanical Engineering Department University of the Basque Country UPV/EHUPlaza de Europa1Donostia-San Sebastian 20018Spain

Diamond like carbon(DLC)coatings typically present good self-lubricating tribological properties that could be of interest in sliding dielectric contacts in multiple electrical *** this work electro-tribological studies have been performed on several DLC coatings against aluminum in different humidity conditions,in which the coefficients of friction(CoFs)and electrical contact resistance(ECR)were continuously *** show that CoF and ECR data can be linked to the properties of the coatings(thickness,finishing,microstructure,residual stresses,and wettability)and the degradation modes of their tribological and electrical ***,electro-tribological data can provide valuable information about the performance of dielectric coatings,the reasons behind it,and assist in the development of the *** also shows potential for on-line monitoring of coated parts in operation.

关键词： DLC electro-tribology ECR-electrical contact resistance coefficient of friction

A trichobezoar in a child with undiagnosed celiac disease: A case report

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World Journal of Gastroenterology 2014年第5期20卷 1357-1360页

作者： iaki irastorza Carlos Tutau Juan Carlos Vitoria Pediatric Gastroenterology and Nutrition Unit University Hospital Cruces and School of Medicine University of the Basque Country Pediatric Gastroenterology and Nutrition Unit University Hospital Cruces

Celiac disease is a chronic, immune-mediated enteropathy caused by a permanent sensitivity to ingested gluten cereals that develops in genetically susceptible individuals. The classic presentation of celiac disease includes symptoms of malabsorption but has long been associated with cognitive, emotional, and behavioral disorders. We describe an 8-year-old patient with nonscarring alopecia and diagnosed with trichotillomania. Furthermore, she presented with a 3-year history of poor appetite and two or three annual episodes of mushy, fatty stools. Laboratory investigations showed a normal hemoglobin concentration and a low ferritin level. Serologic studies showed an elevated tissue immunoglobulin G anti-tissue transglutaminase level. A duodenal biopsy showed subtotal villous atrophy and crypt hyperplasia, and a large gastric trichobezoar was found in the stomach. immediately after beginning a gluten-free diet, complete relief of trichotillomania and trichophagia was achieved. in this report, we describe a behavioral disorder as a primary phenomenon of celiac disease, irrespective of nutritional status.

关键词： Celiac disease Trichobezoar Trichotillomania Behavioral disorder Malabsorption syndrome

Multisensory mechanisms of gait and balance in Parkinson’s disease:an integrative review

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Neural Regeneration Research 2025年第1期20卷 82-92页

作者： Stiven Roytman Rebecca Paalanen Giulia Carli Uros Marusic Prabesh Kanel Teus van Laar Nico i.Bohnen Department of Radiology University of MichiganAnn ArborMIUSA Department of Neurology University of MichiganAnn ArborMIUSA Morris K.Udall Center of Excellence for Parkinson’s Disease Research University of MichiganAnn ArborMIUSA institute for Kinesiology Research Science and Research Centre KoperKoperSlovenia Department of Health Sciences Alma Mater Europaea–ECMMariborSlovenia Parkinson’s Foundation Research Center of Excellence University of MichiganAnn ArborMIUSA Department of Neurology University of GroningenUniversity Medical Center GroningenGroningenThe Netherlands Neurology Service and GRECC VA Ann Arbor Healthcare SystemAnn ArborMIUSA

Understanding the neural underpinning of human gait and balance is one of the most pertinent challenges for 21st-century translational neuroscience due to the profound impact that falls and mobility disturbances have on our aging *** and gait control does not happen automatically,as previously believed,but rather requires continuous involvement of central nervous *** effectively exert control over the body,the brain must integrate multiple streams of sensory information,including visual,vestibular,and somatosensory *** mechanisms which underpin the integration of these multisensory signals are the principal topic of the present *** multisensory integration theories focus on how failure of cognitive processes thought to be involved in multisensory integration leads to falls in older *** emphasis,however,has been placed on specific contributions of individual sensory modalities to multisensory integration processes and cross-modal interactions that occur between the sensory modalities in relation to gait and *** the present work,we review the contributions of somatosensory,visual,and vestibular modalities,along with their multisensory intersections to gait and balance in older adults and patients with Parkinson’s *** also review evidence of vestibular contributions to multisensory temporal binding windows,previously shown to be highly pertinent to fall risk in older ***,we relate multisensory vestibular mechanisms to potential neural substrates,both at the level of neurobiology(concerning positron emission tomography imaging)and at the level of electrophysiology(concerning electroencephalography).We hope that this integrative review,drawing influence across multiple subdisciplines of neuroscience,paves the way for novel research directions and therapeutic neuromodulatory approaches,to improve the lives of older adults and patients with neurodegenerative diseases.

关键词： aging balance encephalography functional magnetic resonance imaging gait multisensory integration Parkinson’s disease positron emission tomography somatosensory vestibular visual

Apolipoprotein A-i binding protein-mediated neuroprotection in glaucomatous neuroinflammation and neurodegeneration

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Neural Regeneration Research 2025年第5期20卷 1414-1415页

作者： Sinwoo Hwang Seunghwan Choi Soo-Ho Choi Keun-Young Kim Yury i.Miller Won-Kyu Ju Hamilton Glaucoma Center and Shiley Eye institute The Viterbi Family Department of OphthalmologyUniversity of California San DiegoLa JollaCAUSA Department of Medicine University of California San DiegoLa JollaCAUSA National Center for Microscopy and imaging Research Department of NeurosciencesUniversity of California San DiegoLa JollaCAUSA

Glaucoma is a multifactorial eye disorder that can cause vision loss and irreversible blindness,affecting individ uals aged 40 to 80 yea rs *** to the aging population,it is expected that the number of people affected by glaucoma will surpass 111 million by 2040 as the disease becomes more *** primarily contributes to optic nerve axon loss and the progressive degeneration of retinal ganglion cells (RGCs),subsequently leading to vision impairment.

关键词： irreversible pass primarily

influences of additives on phosphoric acid treatment of titanium dioxide as a novel white pigment

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Journal of Advanced Ceramics 2015年第3期4卷 211-216页

作者： aki MATSUKURA Hiroaki ONODA Department of informatics and Environmental Sciences Kyoto Prefectual University1-5Shimogamo Nakaragi-cyoSakyo-kuKyoto 606-8522Japan

Titanium dioxide is a photocatalytically active substance used as a white pigment for *** sunlight,titanium dioxide catalyzes decomposition of a certain amount of sebum on the skin by ultraviolet ***,a novel white pigment for use in cosmetics was developed from titanium dioxide and phosphoric acid at pH=4 with and without glycerin,sodium lactate,lactic acid,and *** chemical composition,powder properties,photocatalytic activity,color phase,and smoothness of the samples were *** of glycerin led to a decline in the intensity of the X-ray diffraction(XRD)peak of TiO_(2) relative to that of the other *** particle size of the materials prepared with and without additives was 0.3μm;however,extensive aggregation was observed in the obtained *** photocatalytic activity of TiO_(2) was inhibited by phosphoric acid *** materials prepared with sodium lactate,lactic acid,and glycerin exhibited higher photocatalytic activity than that prepared without *** obtained materials showed a high reflectance in the range of visible light,and the L^(*)values in L^(*)a^(*)b^(*) color space were high(where L^(*)defines lightness,a^(*) denotes the red/green value,and b^(*) the yellow/blue value).These results indicate that the samples prepared in this work are suitable for use as white pigments.

关键词： phosphoric acid titanium dioxide photocatalytic activity particle size

Accurate real-time truck simulation via semirecursive formulation and Adams-Bashforth-Moulton algorithm

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Acta Mechanica Sinica 2019年第3期35卷 641-652页

作者： Yongjun Pan Yansong He aki Mikkola School of Automotive Engineering Chongqing UniversityChongqing 400044China Department of Mechanical Engineering Lappeenranta University of Technology53850 LappeenrantaFinland

in this paper, a tailored four-step Adams-Bashforth-Moulton (ABM) algorithm is applied to a semirecursive formulation to perform a real-time simulation of a semitrailer truck. in the ABM algorithm, each integration step involves two function evaluations, namely predictor and corrector. This is fundamentally different when compared to the classic fourth-order Runge-Kutta (RK) integrator approach that contains four function evaluations. A semitrailer truck under investigation is modeled in term of a semirecursive method and simulated by using the presented ABM algorithm. The results show that the four-step ABM method can reduce CPU time almost 50% for solving the truck dynamics with very similar accuracy, in comparison to the fourth-order RK method. The presented ABM algorithm could be used in the semirecursive formulation to carry out accurate real-time simulation of medium-large vehicle systems.

关键词： Numerical algorithm Semirecursive formulation Vehicle dynamics Computational efficiency

Karyotype differentiation and reproductive isolation among natural populations of Drosophila lacertosa

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Cell Research 2003年第6期13卷 491-497页

作者： HiDE aki WATABE,TADASHi AOTSUKA Biological Laboratory Sapporo College Hokkaido University of Education Sapporo 002-8502 Japan Department of Biology Tokyo Metropolitan University Hachioji-shi 192-0397 Japan

Drosophila lacertosa is widely distributed from northern india to Far East of Russia throughout China. We have studied geographical distributions of three kinds of chromosomal karyotypes, type D (2n=10, 4 pairs of V-shaped metacentric chromosomes and a pair of micro-chromosomes), type L (2n=10, 5V with a pair of large-sized hetero chromatic autosomes) and type M (2n=10, 5V with middle-sized ones). Type D was found exclusively in local populations of D. lacertosa distributed in Yun-Gui Plateau, southwestern China. Both type L and M have a wide range of distribution, and the former occurred in subtropical regions of China including Taiwan island, whereas the latter in cool temperate regions of East Asia covering Far East of Russia, Korea and the Japan islands. A strong pre mating isolation was detected between flies with type D and those with type L or M. These data demonstrate that genetic differentiation leading to cryptic speciation might have occurred in natural populations of Drosophila lacertosa.

关键词： Drosophila lacertosa karyotype differentiation geographic distribution reproductive isolation cryptic speciation.

Fabrication of Mie-resonant silicon nanoparticles using laser annealing for surface-enhanced fluorescence spectroscopy

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Microsystems & Nanoengineering 2024年第2期10卷 133-141页

作者： Tatsuya Fukuta Ryo Kato Takuo Tanaka Taka-aki Yano institute of Post-LED Photonics Tokushima University2-1 Minami-JosanjimaTokushima770-8506Japan innovative Photon Manipulation Research Team RIKEN Center for Advanced PhotonicsWakoSaitama351-0198Japan Metamaterials Laboratory RIKEN Cluster for Pioneering ResearchWakoSaitama351-0109Japan

Silicon nanostructures with unique Mie resonances have garnered considerable attention in the field of ***,we present a simple and efficient method for the fabrication of silicon(Si)nanoparticle substrates using continuous-wave(CW)laser *** resulting silicon nanoparticles exhibit Mie resonances in the visible region,and their resonant wavelengths can be precisely ***,laser-annealed silicon nanoparticle substrates show a 60-fold enhancement in *** tunable and fluorescence-enhancing silicon nanoparticle platform has tremendous potential for highly sensitive fluorescence sensing and biomedical imaging applications.

关键词： nanoparticles annealing resonant