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Is there correlation between pancreatic enzyme and radiological severity in acute pancreatitis?

World Journal of Gastroenterology 2008年第15期14卷 2401-2405页

作者： Yeon Soo kim Byung seok Lee seok hyun kim Jae Kyu Seong hyun Yong Jeong Heon Young Lee Departments of Internal Medicine Daejeon St. Mary's Hospital Medical College of the Catholic University of Korea Korea Department of Internal Medicine Chungnam National University Hospital Daejeon 301721 Korea

AIM: To investigate the correlation between the changes of pancreatic enzyme, the biochemical markers and the clinical results according to the Balthazar computer tomography (CT) grade. METHODS: Between July 2004 and July 2005, we reviewed the charts of 119 patients who were admitted to our hospital with acute pancreatitis. RESULTS: Eighty-three patients (69.7%) were male, and the mean age of the patients was 57 ± 15.7 years. The biliary pancreatitis patients had an older mean age. Forty-nine patients (41.1%) had biliary pancreatitis and forty-six (38.6%) had alcoholic pancreatitis. Group 3 patients had a longer duration of pain (2.51 ± 1.16 vs 3.17 ± 1.30 vs 6.56 ± 6.13, P < 0.001), a longer period of fasting (7.49 ± 4.65 vs 10.65 ± 5.54 vs 21.88 ± 13.81, P < 0.001) and a longer hospital stay (9.17 ± 5.34 vs 14.63 ± 8.65 vs 24.47 ± 15.52, P < 0.001) than the other groups. On the univariate analysis, the factors that affected the radiological grade were the leukocyte count at admission (P = 0.048), the hemoglobin (P = 0.016) and total bilirubin concentrations (P = 0.023), serum lipase (P = 0.009), the APACH Ⅱ scores at admission (P = 0.017), the APACH Ⅱ scores after 24 h (P = 0.031), the C-reactive protein (CRP) titer (P = 0.0001) and the follow up CRP titer (P = 0.003). But the CRP level (P = 0.001) and follow up CRP titer (P = 0.004) were only correlated with the radiological grade on multivariate analysis. According to the ROC curve, when we set the CRP cut off value at 83 mg/L, the likelihoodratio for a positive test was 3.84 and the likelihood ratio for a negative test was 0.26 in group 3. CONCLUSION: In conclusion, our study suggests that the CRP with the radiological severity may be used to estimate the severity of acute pancreatitis.

关键词： Acute pancreatitis Computed tomography C-reactive protein

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EAFoC： Enterprise Architecture Framework Based on Commonality

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Journal of Computer Science & Technology 2006年第6期21卷 952-964页

作者： Jin-Woo kim Ju-Hum Kwo Young-Gab kim Chee-Yang Song hyun-seok kim Doo-Kwon Baik Department of Computer Science and Engineering Korea University 1 5-Ga Anam-Dong Sungbuk-Ku Seoul 136-701 Korea Department of Software Engineering Sang-Ju National University 386 Street Kajang-Dong Sang-Ju 742-711 Korea

The recent rapid development in information systems （ISs） has resulted in a critical need for integration and interoperability between heterogeneous ISs in various domains, using specific commonalities. However, stovepipe systems have been caused due to inconsistencies in planning IS architecture among stakeholders. So far, there has been no research on an enterprise architecture framework （EAF） that can satisfy with the coefficient factors of system architecture （SA） and enterprise architecture （EA）. This paper proposes a new EAF that can resolve the problems inherent in existing legacy EAFs and their features. EAFoC （Enterprise Architecture Framework based on Commonality） is based on commonality that can be satisfied as the coefficient factors in both SA and EA within a common information technology （IT） domain. Thus, it should be possible to integrate an established heterogeneous framework for each stakeholder＇s view. Consequently, the most important contribution of this paper is to establish the appropriate EAFoC for the development of consistent IS architecture, smooth communication among stakeholders, systematic integration management of diversified and complicated new IT technologies, interoperability among heterogeneous ISs, and reusability based on commonality with other platforms.

关键词： enterprise architecture (EA) enterprise architecture framework based on commonality (EAFoC) enterprise integration (El) requirements engineering process system architecture (SA)

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Spectrum of final pathological diagnosis of gastric adenoma after endoscopic resection

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World Journal of Gastroenterology 2011年第47期17卷 5177-5183页

作者： Kwan Woo Nam Kyu Sang Song Heon Young Lee Byung seok Lee Jae Kyu Seong seok hyun kim Hee seok Moon Eaum seok Lee hyun Yong Jeong Gastroenterology Center Sun Hospital Pathologic Department Chung-Nam National University Hospital Gastroenterology Unit of Internal Medicine Department Chung-Nam National University Hospital

AIM: To investigate how many discrepancies occur in patients before and after endoscopic treatment of referred adenoma and the reason for these results. METHODS: We retrospectively reviewed data from 554 cases of 534 patients who were referred from primary care centres for adenoma treatment and treated for endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD) at Chungnam National University Hospital, from July 2006 to June 2009. Reendoscopy was examined in 142 cases and biopsywas performed in 108 cases prior to treatment. Three endoscopists (1, 2 and 3) performed all EMRs or ESDs and three pathologists (1, 2 and 3) diagnosed most of the cases. Transfer notes, medical records and endoscopic pictures of these cases were retrospectively reviewed and analyzed. RESULTS: Adenocarcinoma was 72 (13.0%) cases in total 554 cases after endoscopic treatment of referred adenoma. When the grade of dysplasia was high (55.0%), biopsy number was more than three (22.7%), size was no smaller than 2.0 cm (23.2%), morphologic type was depressed (35.8%) or yamada type Ⅳ (100%), and color was red (30.9%) or mixed-or-undetermined (25.0%), it had much more malignancy rate than the others (P < 0.05). All 18 cases diagnosed as adenocarcinoma in the re-endoscopic forceps biopsy were performed by endoscopist 1. There were different malignancy rates according to the pathologist (P = 0.027). CONCLUSION: High grade dysplasia is the most important factor for predicting malignancy as a final pathologic diagnosis before treating the referred gastric adenoma. This discrepancy can occur mainly through inappropriately selecting a biopsy site where cancer cells do not exist, but it also depends on the pathologist to some extent.

关键词： Discrepancy Adenoma High grade dyspla-sia Endoscopic mucosal resection Endoscopic submu-cosal dissection

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Risk factors and therapeutic results of early local recurrence after transcatheter arterial chemoembolization

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World Journal of Gastroenterology 2014年第22期20卷 6995-7004页

作者： Woo Sun Rou Byung seok Lee Hee seok Moon Eaum seok Lee seok hyun kim Heon Young Lee Division of Gastroenterology Department of Internal MedicineChungnam National University College of MedicineDaejeon 301-721South Korea Division of Gastroenterology Department of Internal MedicineChungnam National University College of MedicineDaejeon 301-721South Kore

AIM: To identify factors affecting early local recurrence after transcatheter arterial chemoembolization (TACE) and investigate treatments and outcomes for local recurrence.

关键词： Chemoembolization Hepatocellular carcinoma Recurrence Survival Lipiodol

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Inhibitory effects of rapamycin on the different stages of hepatic fibrosis

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World Journal of Gastroenterology 2014年第23期20卷 7452-7460页

作者： Yun Jeung kim Eaum seok Lee seok hyun kim Heon Young Lee Seung Moo Noh Dae Young Kang Byung seok Lee Department of Internal Medicine Chungnam National University School of MedicineDaejeon 301-721South Korea Department of Surgery Chungnam National University School of MedicineDaejeon 301-721South Korea Department of Pathology Chungnam National University School of MedicineDaejeon 301-721South Korea

AIM: To investigate and compare the inhibitory effects of rapamycin in the different stages of liver fibrosis.

关键词： Liver cirrhosis Sirolimus Transforming growth factor beta Platelet-derived growth factor Ribosomal protein S6 kinases

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Exploring the experimental study and density functional theory calculations of symmetric and asymmetric chalcogen atoms interacted molybdenum dichalcogenides for lithium-ion batteries

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Journal of Materials Science & Technology 2023年第31期162卷 44-56页

作者： Dhanasekaran Vikraman Sajjad Hussain Zeesham Abbas K.Karuppasamy Woo-seok Kang P.Santhoshkumar A.Kathalingam Jongwan Jung hyun-seok kim Division of Electronics and Electrical Engineering Dongguk University-SeoulSeoul 04620Republic of Korea Department of Nanotechnology and Advanced Materials Engineering Sejong UniversitySeoul 05006Republic of Korea Hybrid Materials Center(HMC) Sejong UniversitySeoul 05006Republic of Korea Millimeter-wave Innovation Technology(MINT)Research Center Dongguk University-SeoulSeoul 04620Republic of Korea

Two-dimensional asymmetric chalcogen atoms attached to Janus nanoparticles have fascinated research attention owing to their distinctive properties and characteristics for various *** paper proposed a facile synthesis to produce efficient molybdenum-based symmetric and asymmetric chalcogens bounded by X Mo X and TeMo X ***,the fabricated X Mo X and TeMo X nanostruc-tures were employed as anodes for lithiumion batteries(LIBs).Assembled LIBs using TeMoS and TeMoSe Janus anodes achieved 2610 and 2073 mAh g^(-1)reversible capacity at 0.1 A g^(-1),respectively for the halfcell configuration,which is outstanding performance compared with previous *** rate capability performances at 0.1-20 A g^(-1)and exceptional cycling solidity confirmed high charge and discharge capacities for TeMo X Janus lithium-ion battery *** addition,the full cell device with TeMoS//LiCoO_(2)configuration explored the discharge capacity of 1605 mAh g^(-1)at 0.1 A g^(-1)which suggests their excellent electrochemical *** density functional theory approximations established the significance of assembled symmetric and asymmetric chalcogen atoms interacted with X Mo X and TeMo X anode materials for ***,the present investigation supports a new approach to creating two-dimensional materials based on asymmetric chalcogen atoms with core metal to effectively increase desirable energy storage characteristics.

关键词： TeMoS TeMoSe Janus Li-ion battery

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Changes in spatial variations of sap flow in Korean pine trees due to environmental factors and their effects on estimates of stand transpiration

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Journal of Mountain Science 2016年第6期13卷 1024-1034页

作者： Minkyu MOON Taek-yu kim Juhan PARK Sungsik CHO Daun RYU Sanguk SUH hyun seok kim National Center for Agro Meteorology 1 Gwanak-roGwanak-guSeou1151-744Republic of Korea National Institute of Environmental Research 42 Hwangyong-roSeo-guIncheon 404-780Republic of Korea Department of Forest Sciences Seoul National UniversityI Gwanak-roGwanak-guSeou1151-921Republic of Korea National Academy of Agricultural Science 166 Nongsaengmyeong-roWanju-gun 565-851Republic of Korea Research Institute for Agriculture and Life Sciences 1 Gwanak-roGwanak-guSeou1151-921Republic of Korea

It is difficult to scale up measurements of the sap flux density(J_S) for the characterization of tree or stand transpiration(E) due to spatial variations in J_S and their temporal *** assess spatial variations in the sap flux density of Korean pine(Pinus koraiensis) and their effects on E estimates,we measured the J_S using Granier-type *** trees,the J_S decreased exponentially with the radial depth,and the J_S of the east aspects were higher than those of the west *** trees,there was a positive relationship between J_S and the tree diameter at breast height,and this positive relationship became stronger as the transpiration demand *** spatial variations that caused large errors in E estimates(i.e.,up to 110.8 % when radial variation was ignored) had varied systematically with environmental factors systematic characteristics in relation to environmental ***,changes in these variations did not generate substantial errors in the E *** our study periods,the differences in the daily E(E_D) calculated by ignoring radial,azimuthal and tree-to-tree variations and the measured E_D were fairly constant,especially when the daily vapor pressure deficit(D_D)was higher than 0.6 k *** results imply that the effect of spatial variations changes on sap flow can be a minor source of error compared with spatial variations(radial,azimuthal and tree-to-tree variations) when considering E estimates.

关键词： Sap flow Environmental factors Pinuskoraiensis Scale-up Stand transpiration

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Unveiling the redox electrochemistry of 1D,urchin-like vanadium sulfide electrodes for high-performance hybrid supercapacitors

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Journal of Energy Chemistry 2023年第4期79卷 569-580页

作者： K.Karuppasamy Dhanasekaran Vikraman Sajjad Hussain Balamurugan Thirumalraj P.Santhoshkumar Hemalatha Parangusan hyun-Chang Park Jongwan Jung hyun-seok kim Division of Electronics and Electrical Engineering Dongguk University-SeoulSeoul 04620Republic of Korea Department of Nanotechnology and Advanced Materials Engineering Sejong UniversitySeoul 05006Republic of Korea School of Materials Science&Engineering Kookmin UniversitySeoul 02707Republic of Korea Millimeter-Wave Innovation Technology Research Center(MINT) Dongguk University-SeoulSeoul 04620Republic of Korea Qatar University Young Scientist Center(QUYSC) Qatar UniversityP.O.Box 2713DohaQatar

Exploring novel versatile electrode materials with outstanding electrochemical performance is the key to the development of advanced energy conversion and storage *** this work,we aim to construct new-fangled one-dimensional(1D)quasi-layered patronite vanadium tetrasulfide(VS_(4))nanostructures by using different sulfur sources,namely thiourea,thioacetamide,and L-cysteine through an ethyleneaminetetraacetic-acid(EDTA)-mediated solvothermal *** as-prepared VS4exhibits several unique morphologies such as urchin,fluffy nanoflower,and polyhedron with appropriate surface *** the prepared nanostructures,the VS_(4)-1@NF nanostructure exhibited excellent electrochemical properties in 6 M KOH solution,and we explored its redox electrochemistry in *** asprepared VS_(4)-1@NF electrode exhibited battery-type redox characteristics with the highest capacity of280 C g^(-1)in a three-electrode ***,it offered a capacity of 123 F g^(-1)in a hybrid twoelectrode set-up at 1 A g^(-1)with the highest specific energy and specific power of 38.5 W h kg^(-1)and750 W kg^(-1),***,to ensure the practical applicability and real-world performance of the prepared hybrid AC@NF//VS_(4)-1@NF cell,we performed a cycling stability test with more than 5,000galvanostatic charge–discharge cycles at 2 A g^(-1),and the cell retained around 84.7%of its capacitance even after 5,000 cycles with a CE of 96.1%.

关键词： Patronite Redox electrochemistry Urchin VS_(4) 1D material Mesoporous

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Tenofovir *** in reducing hepatocellular carcinoma risk in patients with chronic HBV infection?-Still an unsolved question

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Hepatobiliary Surgery and Nutrition 2021年第1期10卷 119-122页

作者： hyun-seok kim Hashem B.El-Serag Section of Gastroenterology and Hepatology Baylor College of MedicineHoustonTXUSA U.S.Michael E.DeBakey Veterans Affairs Medical Center HoustonTXUSA

Chronic hepatitis B virus(CHB)infection affects approximately 250 million persons worldwide(1).CHB is a major risk factor for liver failure,cirrhosis,and hepatocellular carcinoma(HCC),accounting for 45-55%of HCC cases(1).The incidence rates of HCC among CHB patients are 0.02-0.2 per 100 person-years in inactive carriers,0.3-0.6 per 100 person-years in those without cirrhosis,and 2.2-3.7 per 100 person-years for those with compensated cirrhosis(2).

关键词： patients hepatocellular infection

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Usefulness of colonic tattooing using indocyanine green in patients with colorectal tumors

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World Journal of Clinical Cases 2018年第13期6卷 632-640页

作者： Jae Ho Park Hee seok Moon In Sun Kwon Gee Young Yun Seo Hee Lee Dae Hwa Park Ju seok kim Sun hyung Kang Eaum seok Lee seok hyun kim Jae Kyu Sung Byung seok Lee hyun Yong Jeong Division of Gastroenterology Department of Internal Medicine Chungnam National University Hospital Chungnam National University college of Medicine Clinical Trials Center Chungnam National University Hospital

AIM To prove that tattooing using indocyanine green(ICG) is feasible in laparoscopic surgery for a colon *** From January 2012 to December 2016, all patients who underwent laparoscopic colonic surgery were retrospectively screened, and 1010 patients with colorectal neoplasms were included. Their lesions were tattooed with ICG the day before the operation. The tattooed group(TG) included 114 patients, and the non-tattooed group(NTG) was selected by propensity score matching of subjects based on age, sex, tumor staging, and operation method(n = 228). In total, 342 patients were enrolled. Between the groups, the changes in [Delta(Δ), preoperative-postoperative] the hemoglobin and albumin levels, operation time, hospital stay, oral ingestion period, transfusion, and perioperative complications were compared. RESULTS Preoperative TG had a shorter operation time(174.76 ± 51.6 min vs 192.63 ± 59.9 min, P < 0.01), hospital stay(9.55 ± 3.36 d vs 11.42 ± 8.23 d, P < 0.01), and postoperative oral ingestion period(1.58 ± 0.96 d vs 2.81 ± 1.90 d, P < 0.01). The Δ hemoglobin(0.78 ± 0.76 g/dL vs 2.2 ± 1.18 g/dL, P < 0.01) and Δ albumin(0.41 ± 0.44 g/dL vs 1.08 ± 0.39 g/dL, P < 0.01) levels were lower in the TG. On comparison of patients in the "N0" and "N1 or N2" groups, the N0 colon cancer group had a better operation time, length of hospital stay, oral ingestion period, Δ hemoglobin, and Δ albumin results than those of the N1 or N2 group. The operation methods affected the results, and laparoscopic anterior resection(LAR) showed similar results. However, for left and right hemicolectomy, both groups showed no difference in operation time or hospital *** Preoperative tattooing with ICG is useful for laparoscopic colectomy, especially in the N0 colon cancer group and LAR.

关键词： Colorectal neoplasm Laparoscopic surgery Endoscopic tattoo Indocyanine green Perioperative

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