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Zircon U-Pb ages and O-Hf isotopes of Quaternary trachytes from the East Sea:Implications for the genesis of low-δ^(18)O magmas

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Geoscience Frontiers 2024年第2期15卷 41-54页

作者： hyun-Ok choi Jihye Oh Chang Hwan Kim Soon Young choi Won Hyuck Kim Chan Hong Park Dokdo Research Center East Sea Research InstituteKorea Institute of Ocean Science and TechnologyUljin 36315Republic of Korea Deep-Sea and Seabed mineral Resources Research Center Korea Institute of Ocean Science and TechnologyBusan 49111Republic of Korea Division of Science Education Kangwon National University1 Gangwondaehak-gilChuncheon-siGangwon-do 24341Republic of Korea

Quaternary intraplate magmatism formed several volcanic islands and seamounts,including Dokdo(DD),Ulleungdo(UD),Simheungtack(ST),Anyongbok,and Isabu in the southwest of the East Sea back-arc *** this study,we present whole-rock geochemical,zircon U–Pb age,and in situ O–Hf isotope data for the submerged volcanic rocks from DD,UD,and ST to provide new insights into the eruption timing of these volcanoes and constrain the magma evolution *** samples used in this study were trachytes and exhibited ferroan,alkalic,and metaluminous to weakly peraluminous *** showed light rare earth element(REE)-enriched patterns with(La/Yb)N ratios of 25.3–31.7 and mostly negative Eu anomalies in a chondrite-normalized REE *** addition,they were enriched in large-ion lithophile elements and high field strength elements;they exhibited positive Pb anomalies and strongly negative Ba,Sr,P,and Ti *** zircons yielded a weighted-mean 206Pb/238U age of 2.61,0.348–0.704,and 2.76–2.94 Ma for the DD,UD,and ST trachytes,*** zircons exhibited lowerδ^(18)O values than normal depleted mantle values,regardless of the crystallization age and spatial distribution of ***δ^(18)O values showed no correlation with U contents or Th/U ratios,indicating that the lowδ^(18)O signatures were of primary magmatic *** Hf isotopic compositions of the zircons were relatively heterogeneous but predominately characterized by positive eHf *** O–Hf mixing modeling revealed that low-δ^(18)O rocks with positive eHf values from the UD and ST volcanoes were derived from a hybrid source of recycled juvenile crustal materials with low-δ^(18)O and positive eHf signatures and an enriched mantle source with normalδ^(18)O and negative eHf *** juvenile oceanic crust in the source was likely metasomatized by seawater at high temperatures prior to *** contrast,the felsic magma that formed the DD volcanoes may have assimilated with regional

关键词： Quaternary intraplate volcanism East Sea Zircon O-Hf isotopes Low-δ^(18)O magma Recycled juvenile oceanic crust

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Hepatic fat quantification magnetic resonance for monitoring treatment response in pediatric nonalcoholic steatohepatitis

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World Journal of Gastroenterology 2015年第33期21卷 9741-9748页

作者： Hong Koh Seung Kim Myung-Joon Kim hyun Gi Kim hyun Joo Shin mi-Jung Lee Department of Pediatrics Severance Pediatric Liver Disease Research GroupSeverance Children’s HospitalYonsei University College of Medicine Department of Radiology and Research Institute of Radiological Science Severance Pediatric Liver Disease Research GroupSeverance Children’s HospitalYonsei University College of Medicine

AIM: To evaluate the possibility of treatment effect monitoring using hepatic fat quantification magnetic resonance(MR) in pediatric nonalcoholic steatohepatitis(NASH).METHODS: We retrospectively reviewed the medical records of patients who received educational recommendations and vitamin E for NASH and underwent hepatic fat quantification MR from 2011 to *** fat fraction(%) was measured using dual- and triple-echo gradient-recalled-echo sequences at *** compliant and non-compliant groups were compared clinically,biochemically,and ***: Twenty seven patients(M:F = 24:3; mean age: 12 ± 2.3 years) were included(compliant group = 22,non-compliant = 5).None of the baseline findings differed between the 2 groups,except for triglyceride level(compliant vs non-compliant,167.7 mg/d L vs 74.2 mg/d L,P = 0.001).In the compliant group,high-density lipoprotein increased and all other parameters decreased after 1-year ***,there were various changes in the non-compliant *** fat fraction(-19.2% vs 4.6,P minotransferase(-110.7 IU/L vs-10.6 IU/L,P = 0.047),total cholesterol(-18.1 mg/d L vs 3.8 mg/d L,P = 0.016),and triglyceride levels(-61.3 mg/d L vs 11.2 mg/d L,P = 0.013) were significantly decreased only in the compliant *** change in body mass index and dual-echo fat fraction showed a positive correlation(ρ = 0.418,P = 0.030).CONCLUSION: Hepatic fat quantification MR can be a non-invasive,quantitative and useful tool for monitoring treatment effects in pediatric NASH.

关键词： Nonalcoholic fatty liver disease Steatohepatitis H

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Influence of glass-based dental ceramic type and thickness with identical shade on the light transmittance and the degree of conversion of resin cement

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International Journal of Oral Science 2018年第1期10卷 44-49页

作者： Soram Oh Su-mi Shin hyun-Jung Kim Janghyun Paek Sung-Joon Kim Tai hyun Yoon Sun-Young Kim Department of Conservative Dentistry Graduate School Kyung Hee University Seoul Korea Department of Prosthodontics School of Dentistry Kyung Hee University Seoul Korea Department of Dentistry School of Medicine Jeju National University Jeju Korea Department of Physics Korea University Seoul Korea and SDepartment of Conservative Dentistry Dental Research Institute School of Dentistry Seoul National University Seoul Korea

The purpose of this study was to assess the influence of the types and thicknesses of glass ceramic plates on light transmittance and compare the degrees of conversion(DC) of resin cement under the ceramic materials. Three ceramic plates with thicknesses of 0.5, 1.0, 2.0, and 4.0 mm were fabricated from each of five commercial ceramic blocks in shade A2: high-translucency and low-translucency IPS Empress CAD(EmpHT and EmpLT); high-translucency and low-translucency IPS *** CAD(EmxHT and EmxLT); and Vita Mark Ⅱ(Vita). The translucency parameter was obtained using a colorimeter. The light transmittance rate was measured using a photodetector attached to an optical power meter. The DC of a resin cement(Variolink N) underneath the ceramic plates was examined by Fourier transform infrared spectroscopy. The translucency parameter, light transmittance rate, and DC showed significant differences by ceramic type and thickness(P mission and DCs, and the EmxLT showed the least light transmission and the lowest DCs. The high-translucency Empress showed significantly higher DCs than the low-translucency types(P 0.05). Both type and thickness of the glass ceramics significantly influenced the light transmittance and DC of the light-cured resin cement beneath the ceramic of the same shade.

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Delayed gait recovery in a stroke patient

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Neural Regeneration Research 2013年第16期8卷 1514-1518页

作者： Jeong Pyo Seo mi Young Lee Yong hyun Kwon Sung Ho Jang Department of Physical Medicine and Rehabilitation College of Medicine Yeungnam University Department of Physical Therapy College of Health and Therapy Daegu Haany University Department of Physical Therapy Yeungnam College of Science & Technology

We report on a stroke patient who showed delayed gait recovery between 8 and 11 months after the onset of intracerebral hemorrhage. This 32-year-old female patient underwent craniotomy and drainage for right intracerebral hemorrhage due to rupture of an arteriovenous malformation. Brain MR images revealed a large leukomalactic lesion in the right fronto-parietal cortex. Diffusion tensor tractography at 8 months after onset revealed that the right corticospinal tract was severely injured. At this time, the patient could not stand or walk despite undergoing rehabilitation from 2 months after onset. It was believed that severe spasticity of the left leg and right ankle was largely responsible, and thus, antispastic drugs, antispastic procedures （alcohol neurolysis of the motor branch of the tibial nerve and an intramuscular alcohol wash of both tibialis posterior muscles） and physical therapy were tried to control the spasticity. These measures relieved the severe spasticity, with the result that the patient was able to stand at 3 months. In addition, the improvements in sensorimotor function, visuospatial function, and cognition also seemed to contribute to gait recovery. As a result, she gained the ability to walk independently on even floor with a left ankle foot orthosis at 11 months after onset. This case illustrates that clinicians should attempt to find the cause of gait inability and to initiate intensive rehabilitation in stroke patients who cannot walk at 3-6 months after onset.

关键词： neural regeneration brain injury stroke diffusion tensor imaging sequelae gait walk motor recovery corticospinal tract rehabilitation intracerebral hemorrhage grants-supported paper neuroregeneration

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Secondary craniofacial necrotizing fasciitis from a distant septic emboli: A case report

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World Journal of Clinical Cases 2022年第31期10卷 11630-11637页

作者： Da-Woon Lee Si-hyun Kwak Hwan-Jun choi Department of Plastic and Reconstructive Surgery College of MedicineSoonchunhyang UniversityCheonan-si 31151South Korea Institute of Tissue Regeneration College of MedicineSoonchunhyang UniversityCheonan-si 31151South Korea

BACKGROUND Craniofacial necrotizing fasciitis(CNF)is an uncommon but fatal infection that can spread rapidly through the subfascial planes in the head and neck *** usually progress rapidly,and early management is necessary to optimize *** SUMMARY A 43-year-old man visited our hospital with left hemifacial swelling involving the buccal and submandibular *** patient had fever for approximately 10 d before visiting the hospital,but did not report any other systemic *** tomography scan demonstrated an abscess with gas *** surgical drainage of the facial abscess,the patient’s systemic condition worsened and progressed to septic *** examination revealed pulmonary and renal *** percutaneous catheter drainage was performed at the renal abscess site,which caused improvement of *** patient showed no evidence of systemic complications during the 4-mo post-operative follow-up *** As the patient did not improve with conventional CNF treatment and symptoms only resolved after controlling the infection,the final diagnosis was secondary CNF with septic *** surgical decompression is important for CNF ***,if symptoms worsen despite early diagnosis and management,such as pus drainage and surgical intervention,clinicians should consider the possibility of a secondary abscess from internal organs.

关键词： Craniofacial necrotizing fasciitis Septic emboli Klebsiella pneumoniae Secondary Case report

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Fabrication of SiC_p/AA5083 composite via friction stir welding

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中国有色金属学会会刊：英文版 2012年第S3期22卷 634-638页

作者： Byung-Wook AHN Don-hyun choi Yong-Hwan KIM Seung-Boo JUNG School of Advanced Materials Science and Engineering Sungkyunkwan University

microstructure and mechanical properties of SiCp /AA5083 composite fabricated by friction stir welding (FSW) were *** influence of the number of FSW passes on the distribution of SiC particles and mechanical properties in the joint was *** one pass,the SiC particles were entangled in the upper side of the stir zone (SZ).However,the particle distribution became more uniform after two passes due to the repeated stirring of the *** the SiC particles facilitate the grain refinement in the SZ by the pinning effect,the particle including region has much smaller grain size than the SZ without SiC *** SiCp /AA5083 composite region exhibits a Vickers hardness of HV90,which is much higher than the value of HV80 in the SZ produced by FSW without SiC particles.

关键词： metal matrix composite SiC particle friction stir welding mechanical property

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Formic acid as an alternative reducing agent for the catalytic nitrate reduction in aqueous media

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Journal of Environmental Sciences 2013年第8期25卷 1696-1702页

作者： Eun-kyoung choi Kuy-hyun Park Ho-bin Lee misun Cho Samyoung Ahn Department of Environmental Education Sunchon National University

Formic acid was used for the nitrate reduction as a reductant in the presence of Pd：Cu/γ-alumina catalysts. The surface characteristics of the bimetallic catalyst synthesized by wet impregnation were investigated by SEM, TEM-EDS. The metals were not distributed homogeneously on the surface of catalyst, although the total contents of both metals in particles agreed well with the theoretical values. Formic acid decomposition on the catalyst surface, its influence on solution pH and nitrate removal efficacy was investigated. The best removal of nitrate （50 ppm） was obtained under the condition of 0.75 g/L catalyst with Pd：Cu ratio （4：1） and two fold excess of formic acid. Formic acid decay patterns resembled those of nitrate removal, showing a linear relationship between kf （formic acid decay） and k （nitrate removal）. Negligible amount of ammonia was detected, and no nitrite was detected, possibly due to buffering effect of bicarbonate that is in situ produced by the decomposition of formic acid, and due to the sustained release of H2 gas.

关键词： formic acid catalytic nitrate reduction Pd:Cu/γ-alumina catalyst H2 supply

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Development and characterization of novel polymorphic microsatellite markers for the Korean freshwater snail Semisulcospira coreana and cross-species amplification using next-generation sequencing

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Journal of Oceanology and Limnology 2020年第2期38卷 503-508页

作者： Yeon Jung PARK mi Nan LEE Eun-mi KIM Jung Youn PARK Jae Koo NOH Tae-Jin choi Jung-Ha KANG Biotechnology Research Division National Institute of Fisheries ScienceBusan 46083Republic of Korea Department of microbiology Pukyoung National UniversityBusan 48513Republic of Korea

Korean freshwater snails of the genus Semisulcospira are widely distributed across East *** has been a very popular nutritional food in Korea,and is an ecologically important water quality indicator because it lives only in clean ***,no microsatellite markers have been generated to study the population genetic diversity of this *** the present study,we developed and characterized 18 novel microsatellite loci from Semisulcospira coreana genomic *** microsatellites were isolated using 454 GS-FLX titanium sequencing and 18 markers were used for genotyping in *** addition,we also tested the cross-species transferability of the microsatellite markers in four additional Semisulcospira *** identified 18 polymorphic loci and the number of alleles per loci,and their polymorphism information content values ranged from 2 to 17 and 0.203 to 0.902,*** observed and expected heterozygosities of the loci ranged from 0.063 to 0.924 and 0.226 to 0.924,*** to the analysis of the cross-species transferability of these markers,four species,***,***,***,and ***,showed a very high transferability(80%–85%).These results show that this set of nuclear markers could be useful for population genetics studies of this species and closely related species.

关键词： Semisulcospira next-generation sequencing(NGS) microsatellite markers cross-species transferability

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Effect of SiC particles on microstructure and mechanical property of friction stir processed AA6061-T4

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中国有色金属学会会刊：英文版 2012年第S3期22卷 614-618页

作者： Don-hyun choi Yong-Il KIM DAE-Up KIM Seung-Boo JUNG School of Advanced Materials Science and Engineering Sungkyunkwan University MEPL Sungkyunkwan University KITECH 838-11Palbok-dong 2-gaDeokjin-guJeonju-cityJeollabuk-do 561-844Korea

Friction stir processing of AA6061-T4 alloy with SiC particles was successfully carried *** particles were uniformly dispersed into an AA6061-T4 *** SiC particles promoted the grain refinement of the AA6061-T4 matrix by *** mean grain size of the stir zone (SZ) with the SiC particles was obviously smaller than that of the stir zone without the SiC *** microhardness of the SZ with the SiC particles reached about HV80 due to the grain refinement and the distribution of the SiC particles.

关键词： friction stir processing AA6061-T4 SiC particles pinning effect

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Curcumin attenuates the release of pro-inflammatory cytokines in lipopolysaccharide-stimulated BV2 microglia

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Acta Pharmacologica Sinica 2007年第10期28卷 1645-1651页

作者： Jae-dong LEE Cheol PARK Yung hyun choi Gi-young KIM Department of microbiology College of Natural Sciences Pusan National UniversityBusan 609-735 Department of Biochemistry Dongeui University College of Oriental MedicineBusan 614-054Korea Faculty of Applied Marine Science Cheju National UniversityJeju-siJeju Special Self-Governing Province 690-756Korea

Aim:Pro-inflammatory mediators,such as prostaglandin E2（PGE2） and nitric oxide（NO）,and pro-inflammatory cytokines such as interleukin （IL）-1β,IL-6,and TNF-α,play pivotal roles in brain *** anti-inflammatory properties are knownto be associated with significant reductions in pro-inflammatory mediators in *** the present study we investigate whether the effects of curcumin onthe production of pro-inflammatory mediators in lipopolysaccharide （LPS）-stimu-lated BV2 ***:Curcumin were administered and their effects onLPS-induced pro-inflammatory mediators were monitored by Western blottingand ***:Curcumin significantly inhibited the release of NO,PGE2,and pro-inflammatory cytokines in a dose-dependent *** alsoattenuated the expressions of inducible NO synthase and cyclooxygenase-2 mRNAand protein ***,curcumin suppressed NF-kB activation via thetranslocation of p65 into the *** data also indicate that curcumin exertsanti-inflammatory properties by suppressing the transcription of proinflammatorycytokine genes through the NF-kB signaling ***:Anti-inflam-matory properties of curcumin may be useful for treating the inflammatory anddeleterious effects of microglial activation in response to LPS stimulation.

关键词： curcumin inducible nitric oxide synthase cyclooxygenase-2 pro-inflammatory cytokines NF-kB

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