检索结果-南通市图书馆

The role of extracellular vesicles in animal reproduction and diseases

在线全文

学校读者我要写书评

暂无评论

Journal of Animal Science and Biotechnology 2022年第6期13卷 1634-1656页

作者： Sangiliyandi Gurunathan Min-Hee Kang hyuk song Nam Hyung Kim Jin-Hoi Kim Department of Stem Cell and Regenerative Biotechnology Konkuk UniversitySeoul 05029Korea Guangdong Provincial Key Laboratory of Large Animal models for Biomedicine Wuyi UniversityJiangmen 529020China

Extracellular vesicles(EVs)are nanosized membrane-enclosed compartments that serve as messengers in cell-to-cell communication,both in normal physiology and in pathological *** can transfer functional proteins and genetic information to alter the phenotype and function of recipient cells,which undergo different changes that positively affect their structural and functional *** fluids are enriched with several subpopulations of EVs,including exosomes,microvesicles(MVs),and apoptotic bodies carrying several cargoes,such as lipids,proteins,and nucleic *** associated with the reproductive system are actively involved in the regulation of different physiological events,including gamete maturation,fertilization,and embryo and fetal *** can influence follicle development,oocyte maturation,embryo production,and endometrial-conceptus *** loaded with cargoes are used to diagnose various diseases,including pregnancy disorders;however,these are dependent on the type of cell of origin and pathological ***-derived microRNAs(miRNAs)and proteins in the placenta regulate inflammatory responses and trophoblast invasion through intercellular delivery in the placental *** review presents evidence regarding the types of extracellular vesicles,and general aspects of isolation,purification,and characterization of EVs,particularly from various types of ***,we discuss EVs as mediators and messengers in reproductive biology,the effects of EVs on placentation and pregnancy disorders,the role of EVs in animal reproduction,in the male reproductive system,and mother and embryo *** addition,we emphasize the role of microRNAs in embryo implantation and the role of EVs in reproductive and therapeutic ***,we discuss the future perspectives of EVs in reproductive biology.

关键词： Embryos Extracellular vesicles Implantation MicroRNA Pregnancy disorders

Interstitial tissue-specific gene expression in mouse testis by intra-tunica albuguineal injection of recombinant baculovirus

在线全文

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2009年第3期11卷 342-350页

作者： Hyun Jung Park Won Young Lee Jin Hoi Kim Jae Hwan Kim Hun Jong Jung Nam Hyung Kim Bo Kyung Kim hyuk song Department of Animal Science College of Natural Science Konkuk University Chung-ju 380-701 Korea CHA Stem Cell Institute Graduate School of Life Science and Biotechnology Pochon CHA University Seoul 135-907 Korea Department of Animal Biotechnology College of Animal Biotechnology Konkuk University Seoul 143-701 Korea Occupation and Environment Department Medical School Konkuk University Chung-ju 380-704 Korea Department of Animal Science College of Agriculture Chungbuk National University Choung-ju Chung-buk 361-763 Korea Department of Physiology Medical School Konkuk University Chung-ju 380-701 Korea

The purpose of this study is to establish a gene delivery system for interstitial tissue-specific protein expression in mice testes using modified recombinant baculovirus. Green fluorescent protein （GFP）-expressing recombinant baculovirus （GFP-baculovirus）, in which the insect cell-specific polyhedron promoter was replaced by the cytomegalovirus （CMV）-IE promoter, was used to transfect testicular cells in vitro, and for intra-tunica albuguineal injection of the interstitial tissue of the testis. GFP expression was monitored in frozen testes sections by fluorescence microscopy. Expression of GFP in testicular tissues was also assessed by reverse transcription polymerase chain reaction （RT-PCR）, and protein expression was assessed by Western blot. Testicular cells in vitro were infected efficiently by modified recombinant GFP-baculovirus. lntra-tunica albuguineal injection of GFP- baculovirus into the mouse testis resulted in a high level of GFP expression in the interstitial tissues. RT-PCR analysis clearly showed GFP gene expression in the testis, particularly interstitial tissues. Intra-tunica albuguineal injection of a modified baculovirus that encoded recombinant rat insulin-like growth factor binding protein （IGFBP）-5 resulted in an increase in IGFBP-5 in testis and semen. In conclusion, we have developed an efficient delivery system for gene expression in vivo in testicular cells, particularly cells of the interstitial tissue using intratunica albuguineal injection of a modified recombinant baculovirus. This method will be particularly relevant for application that requires gene delivery and protein expression in the testicular cells of the outer seminiferous tubule of the testis.

关键词： intra-tunica albuguineal injection recombinant baculovirus testis gene delivery

Fourier and wavelet transformations application to fault detection of induction motor with stator current

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Central South University 2010年第1期17卷 93-101页

作者： LEE Sang-hyuk 王一奇 song Jung-il School of Mechatronics Changwon National University

Fault detection of an induction motor was carried out using the information of the stator current. After synchronizing the actual data, Fourier and wavelet transformations were adopted in order to obtain the sideband or detail value characteristics under healthy and various faulty operating conditions. The most reliable phase current among the three phase currents was selected using an approach that employs the fuzzy entropy measure. Data were trained with a neural network system, and the fault detection algorithm was verified using the unknown data. Results of the proposed approach based on Fourier and wavelet transformations indicate that the faults can be properly classified into six categories. The training error is 5.3×10-7, and the average test error is 0.103.

关键词： Fourier transformation wavelet transformation induction motor fault detection

An Efficient and Spam-Robust Proximity Measure Between Communication Entities

在线全文

学校读者我要写书评

暂无评论

Journal of Computer Science & Technology 2013年第2期28卷 394-400页

作者： Joo hyuk Jeon Jihwan song Jeong Eun Kwon Yoon Joon Lee Man Ho Park Myoung Ho Kim Department of Computer Science Korea Advanced Institute of Science and Technology Biz Solution Team SK Telecom Information Technology R&D Center Mobile Communication Convergence Research Team Electronics and Telecommunications Research Institute

Electronic communication service providers are obliged to retain communication data for a certain amount of time by their local laws. The retained communication data or the communication logs are used in various applications such as crime detection, viral marketing, analytical study, and so on. Many of these applications rely on effective techniques for analyzing communication logs. In this paper, we focus on measuring the proximity between two communication entities, which is a fundamental and important step toward further analysis of communication logs, and propose a new proximity measure called ESP （Efficient and Spam-Robust Proximity measure）. Our proposed measure considers only the （graph- theoretically） shortest paths between two entities and gives small values to those between spam-like entities and others. Thus, it is not only computationally efficient but also spam-robust. By conducting several experiments on real and synthetic datasets, we show that our proposed proximity measure is more accurate, computationally efficient and spam-robust than the existing measures in most cases.

关键词： proximity closeness spam electronic communication

Polarization-sensitive intensity diffraction tomography

在线全文

学校读者我要写书评

暂无评论

Light(Science & Applications) 2023年第6期12卷 1071-1083页

作者： Seungri song Jeongsoo Kim Taegyun Moon Baekcheon Seong Woovin Kim Chang-hyuk Yoo Jun-Kyu Choi Chulmin Joo Department of Mechanical Engineering Yonsei UniversitySeoul 03722Republic of Korea Small Machines Company Ltd.Seoul 04808Republic of Korea

Optical anisotropy,which is an intrinsic property of many materials,originates from the structural arrangement of molecular structures,and to date,various polarization-sensitive imaging(PSI)methods have been developed to investigate the nature of anisotropic *** particular,the recently developed tomographic PSI technologies enable the investigation of anisotropic materials through volumetric mappings of the anisotropy distribution of these ***,these reported methods mostly operate on a single scattering model,and are thus not suitable for three-dimensional(3D)PSI imaging of multiple scattering ***,we present a novel reference-free 3D polarization-sensitive computational imaging technique—polarization-sensitive intensity diffraction tomography(PS-IDT)—that enables the reconstruction of 3D anisotropy distribution of both weakly and multiple scattering specimens from multiple intensity-only measurements.A 3D anisotropic object is illuminated by circularly polarized plane waves at various illumination angles to encode the isotropic and anisotropic structural information into 2D intensity *** information are then recorded separately through two orthogonal analyzer states,and a 3D Jones matrix is iteratively reconstructed based on the vectorial multi-slice beam propagation model and gradient descent *** demonstrate the 3D anisotropy imaging capabilities of PS-IDT by presenting 3D anisotropy maps of various samples,including potato starch granules and tardigrade.

关键词： materials anisotropy intensity

Dynamic recrystallization behavior and microstructural evolution of Mg alloy AZ31 through high-speed rolling

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2018年第10期34卷 1747-1755页

作者： Jeong Hun Lee Jong Un Lee Sang-Hoon Kim Seok Weon song Chong Soo Lee Sung hyuk Park Ulsan Regional Division Korea Institute of Industrial Technology School of Materials Science and Engineering Kyungpook National University Technical Research Laboratories POSCO Graduate Institute of Ferrous Technology Pohang University of Science and Technology

High-speed rolling （HSR） is known to improve the workability of Mg alloys significantly, which makes it possible to impose a large reduction in a single pass without fracture. In the present study, dynamic recrystallization （DRX） behavior and microstructural and textural variations of Mg alloy AZ31 dur-ing a HSR process were investigated by conducting rolling with different imposed reductions in the range of 20%-80% at a high rolling speed of 470 m/min and 400℃. High-strain-rate deformation during HSR suppresses dislocation slips but promotes twinning, which results in the formation of numer-ous twins of several types, i.e., {10-12} extension twins, {10-11} and {10-13} contraction twins, and {10-11}-{10-12} double twins. After twinning, high strain energy is accumulated in twin bands because their crystallographic orientations are favorable for basal slips, leading to subsequent DRX at the twin bands. Accordingly, twinning activation and twinning-induced DRX behavior play crucial roles in accommodating plastic deformation during HSR and in varying microstructure and texture of the high- speed-rolled （HSRed） sheets. Area fraction of fine DRXed grains formed at the twin bands increases with increasing rolling reduction, which is attributed to the combined effects of increased strain, strain rate, and deformation temperature and a decreased critical strain for DRX. Size, internal strain, and texture intensity of the DRXed grains are smaller than those of unDRXed grains. Therefore, as rolling reduction increases, average grain size, stored internal energy, microstructural inhomogeneity, and basal texture intensity of the HSRed sheets gradually decrease owing to an increase in the area fraction of the DRXed grains.

关键词： Magnesium alloy High-speed rolling Twinning Dynamic recrystallization Microstructure

Design of BPS digital frontend for software defined radio receiver

在线全文

学校读者我要写书评

暂无评论

Journal of Central South University 2015年第12期22卷 4709-4716页

作者：王洪梅 KIM Jae-hyung 王法广 LEE Sang-hyuk 王雪松 School of Information and Electrical Engineering China University of Mining and Technology School of Mechatronics Changwon National University Collaborative Innovation Center of Intelligent Mining Equipment China University of Mining and Technology Electrical and Electronic Engineering Xi'an Jiaotong-Liverpool University

In radio receivers,complete implementation of the software defined radio(SDR) concept is mainly limited by *** on bandpass sampling(BPS) theory,a flexible digital frontend(DFE) platform for SDR receiver is *** order to increase the processing speed,Gigabit Ethernet was applied in the platform at speed of 5×10~8 bit/*** appropriate design of interpolant according to the position of input RF signals,multi-band receiving can be realized in the platform with suppression more than 35 d B without changing hardware.

关键词： software defined radio(SDR) digital frontend bandpass sampling

Nanoscale Materials and Deformable Device Designs for Bioinspired and Biointegrated Electronics

在线全文

学校读者我要写书评

暂无评论

Accounts of Materials Research 2021年第4期2卷 266-281页

作者： Woongchan Lee Huiwon Yun Jun-Kyul song Sung-hyuk Sunwoo Dae-Hyeong Kim Center for Nanoparticle Research Institute for Basic Science(IBS)Seoul 08826Republic of Korea School of Chemical and Biological Engineering Institute of Chemical ProcessesSeoul National UniversitySeoul 08826Republic of Korea

Electronic devices whose structural and functional features are inspired by living creatures have unique performance and unconventional features that are not found in conventional electronic *** addition to such bioinspired electronics,with the rise of new fields such as personalized healthcare,mobile electronics,and big-data analysis,biointegrated electronic devices that can collect biomedical information from the human body through various biosensors and deliver appropriate therapeutic feedback stimulations in real time on the spot where immediate treatment is needed have become *** body parts and internal organs of living creatures,including humans,have curvilinear shapes and comprise mechanically soft tissues,such bioinspired and biointegrated electronic devices are required to match the soft and deformable features of biological *** soft and deformable features of electronic devices can be achieved by employing flexible and stretchable materials and unconventional device design *** soft materials and deformable device designs dissipate stress originating from mechanical deformation of the device and thus retard crack generation and/or propagation in the ***,technologies for nanoscale materials have shown a significant level of progress on their material performance and processing *** nanoscale dimension of the electronic materials could achieve extremely small flexural rigidity in comparison to the bulk state of the same ***,techniques to form a well-percolated network of nanomaterials in the elastomeric matrix and to build a pathway for the facile electron and hole transport inside the polymer have induced dramatic performance advances of soft electronic materials,which led to nanocomposites that can accomplish both high mechanical deformability and high electrical performance at the same *** addition,deformable device designs such as buckled structures and serpentine des

关键词： buckling rigidity electronics

The brain activation pattern of the medial temporal lobe during chewing gum: a functional MRI study

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2017年第5期12卷 812-814页

作者： Youn-Hee Choi Woo hyuk Jang Sang-Uk Im Keun-Bae song Hee-Kyung Lee Han Do Lee You Sung Seo Sung Ho Jang Department of Preventive Dentistry School of Dentistry Kyungpook National University Department of Occupational Therapy College of Health Science Kangwon National University Departments of Physical Medicine and Rehabilitation College of Medicine Yeungnam University

The human brain is known to be influenced by environmental stimuli（Feeney et al.,1982;Kaplan,1988）.Therefore,research on the brain activation pattern by external stimuli has been an important topic in neuroscience（Kaplan,1988）.Chewing gum has been known to have a positive effect on cognition,including alertness,attention,cognitive processing speed,

关键词： MRI The brain activation pattern of the medial temporal lobe during chewing gum a functional MRI study