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Effect of Air Pollution in Vinyl Chloride Workplaces on Workers’ Health

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Effect of Air Pollution in Vinyl Chloride Workplaces on Work...

2007中国科协年会

作者： Ma Shiwei Tang Naijun Zhang Peng Huang Jing Zhao Lijun Han Wei Chen Xi Department of Occupational and Environmental Health Sciences,school of Public Health,tianjin medical university,tianjin 300070,china

Objective To investigate the result of comet assay among vinyl chloride monomer(VCM)workers. Evaluate the main influencing factors of DNA damage and abnormal liver function tests(LFTs).Method comet assay was employed to detect DNA damage and the CASP sofrware was used to analyze the *** genotypes of GSTT1,GSTM1 and CYP2E1 were determined by polymerase chain reaction(PCR)and/or restriction fragment length polymorphtsm(RFLP)on white blood cell *** excessive activity of serum alanine aminotransferase(ALT)and abnormal manifestation of liver B-ultrasound were used as the parameters of liver *** to the health examination data over the years,we studied the influening factors from the following aspects:hereditary factors(gene polymorphism of vinyl chloried metabolic enzyme),living habit (smoking,drinking)and vinyl chloride *** Multi-elements Logistic regression analysts and Spearrman rank correlation analysis showed that CYP2E1 clc2/c2c2,age,drink habit and the average VCM exposure dose were associated with the DNA ***2E1 c1c2/c2c2 and drink habit were associated with the abnormal *** rank correlation analysis showed the average VCM exposure dose correlated with level of plasma enzymes(ALT).Conclusion The DNA damage is influenced by genotypes of CYI2E1, drinking and the average VCM exposure *** abnormal LFTs is influenced by genotypes of CYP2E1,drink and the average VCM exposure *** should pay more attention to the VCM workers’ DNA and liver damage from the aspects such as hereditary factors,living habit and vinyl chloride *** health surveillance of VCM workers should be given full consideration.

关键词： VCM comet assay SCGE genetic polymorphism abnormal LEFs

一种有效提高GLP-1体内半衰期的方法及应用

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一种有效提高GLP-1体内半衰期的方法及应用

2011新型疫苗与抗体创制关键技术及质量控制研讨会

作者： Xuemin Zheng~1,Gang Fu~3,Xin Li~2,Yuli Wang~3,Ying Li~4,Weiren Xu~3 and Min Gong~(3*) 1 Department of Pharmaceutical Analysis,tianjin university of Traditional Chinese Medicine,china, 2 Division of pharmacology,tianjin medical university,china, 3 tianjin Key Lab of Molecular Design and Drug Discovery,tianjin Institute of Pharmaceutical Research,china, 4 school of Life Science,university of Birmingham,UK

目的 :胰高血糖素样肽1(GLP-1)的多种生理特性使它成为了治疗二型糖尿病的重要候选药物。然而,由于其在体内易被二肽基肽酶4(DPP-Ⅳ)降解,所以其体内半衰期十分短暂。本研究旨在保证GLP-1生物活性的同时提高其稳定性,延长体内半衰期。

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Simutaneous Determination of amygdalin,paeoniflorin,naringin in Xuefu Zhuyu Capsule by HPLC with Evaporative Light Scattering Detection

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Simutaneous Determination of amygdalin,paeoniflorin,naringin...

2009年全国中药学术研讨会

作者： Ying Gao~(1,2),Wen-Yuan Gao~(1**),Feng-Ge Li~3,Xin-Ying Yang~3,Xuan Dong~1 (1.school of Pharmaceutical Science and Technology,tianjin university,tianjin 300072,china 2.medical College of Chinese People’s Armed Police Forces, tianjin 300162,china 3.tianjin Hongrentang Pharmaceutical Co.,Ltd.,tianjin 300122,china)

A high performance liquid chromatography with evaporative light scattering detection method was developed for simultaneous determination of amygdalin,paeoniflorin,naringin in the Chinese medicinal preparation"Xuefu Zhuyu Capsule".The analysis was performed by reverse phase gradient elution,using an aqueous mobile phase (containing 1%acetic acid) modified by *** flow rate was 0.8 mL/min and the temperature of column was 30℃.Amygdalin,paeoniflorin and naringin could be baseline *** average recovery rates were 97.47%,99.19%,98.38%,RSD were 2.6%,1.9%,1.3%for amygdalin,paeoniflorin and naringin, respectively(n=6).This method could be used for quality assessment of this herbal medicine.

关键词： Xuefu Zhuyu Capsule Amygdalin Paeoniflorin Naringin HPLC

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高强度聚焦超声焦域的实验研究

中国超声医学杂志 2012年第5期28卷 385-388页

作者：王韶林肖雪刚陈晓瑞菅喜岐天津医科大学生物医学工程学院

目的通过含液晶感温膜的仿组织体模和离体牛肝组织实验,研究高强度聚焦超声(HIFU)焦域大小随不同参数的变化。方法设定不同输入功率、辐照时间和辐照深度进行实验,用相机分别记录不同参数下仿组织体模和牛肝组织内形成的焦域,并进行数... 详细信息

目的通过含液晶感温膜的仿组织体模和离体牛肝组织实验,研究高强度聚焦超声(HIFU)焦域大小随不同参数的变化。方法设定不同输入功率、辐照时间和辐照深度进行实验,用相机分别记录不同参数下仿组织体模和牛肝组织内形成的焦域,并进行数据统计分析。结果仿组织体模焦域内液晶感温膜显示65.7℃以上区域呈椭圆形;HIFU焦域长、短轴随输入功率、辐照时间的增加而增大,随辐照深度的增加而减小,且长轴变化较短轴明显,同时存在辐照时间阈值。结论含有液晶感温膜的仿组织体模可用于研究HIFU焦域随不同影响因素的变化情况,结合离体牛肝组织实验对比,为HIFU剂量研究提供参考依据。

关键词： HIFU 仿组织体模离体牛肝组织

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带有评价准则的数据包络分析模型

天津大学学报（自然科学与工程技术版） 2002年第5期35卷 593-596页

作者：郝海顾培亮卢奇天津大学管理学院

为了获取决策单元的更多信息 ,更好地进行评价和决策 ,在数据包络分析理论的基础上建立了带有一些“评价准则”的DEA模型 ,以便在最大的输入能得到最大的输出和最小的输入能得到最小的输出等准则下评价决策单元 .

关键词：数据包络分析模型决策单元相对效率评价准则 C^2R模型参照准则

带有参数的数据包络分析C^2GS^2模型——PC^2GS^2

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系统工程与电子技术 2003年第8期25卷 949-953,988页

作者：郝海顾培亮尹春华天津大学管理学院

数据包络分析是系统工程的一种重要方法 ,特别适宜处理多输入、多输出的复杂系统的评价问题。在数据包络分析C2 GS2 模型的基础上 ,通过对评估决策单元的输入进行调整 ,得出了一个带有参数的C2 GS2 ———PC2 GS2 模型。探讨了模型的有... 详细信息

数据包络分析是系统工程的一种重要方法 ,特别适宜处理多输入、多输出的复杂系统的评价问题。在数据包络分析C2 GS2 模型的基础上 ,通过对评估决策单元的输入进行调整 ,得出了一个带有参数的C2 GS2 ———PC2 GS2 模型。探讨了模型的有关性质 ,给出了阈值的概念 ,并通过理论分析和实例验证。

关键词：数据包络分析决策单元 C2GS2模型阈值

“family and community endowment” and function analysis for old caring of community public service facilities

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“family and community endowment” and function analysis for...

2009 IEEE the 16th International Conference on Industrial Engineering and Engineering Management

作者： WANG Hong-na LIU Ying-zong CHEN Xin-tao school of Management tianjin university P.O.Box 9116 tianjin 300072 P. R. china

Traditional family endowment and social endowment both have limitations in china at present whereas the new endowment mode "Family and community endowment" integrates advantages of the two. The paper analyzed the old people’s choice on living style under the new mode. Residential districts are the optimum environment for old caring, and public service facilities in residential districts have to satisfy the old people’s life necessities. There are peculiarities in the old age: physiological natural aging and organic lesions in physiology, being afraid of loneliness and desiring to be looked after in psychology. So the old people have the endowment demands of "living with security, being nursed in time and enjoying independence, achievement and entertainment". Public service facilities in residential districts must meet these demands and correspondingly provide functions of residing and feeding, medical care system, maintaining the old people’s survival value and social communicating.

关键词： Endowment function analysis demand family and community endowment living style public service facilities residential district planning social endowment traditional family endowment

A Preliminary Study of Epigastrium Dual Energy Virtual Non-Contrast CT of Dual Source CT

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A Preliminary Study of Epigastrium Dual Energy Virtual Non-C...

中华医学会第16次全国放射学学术大会

作者： Jin Peng Longjiang Zhang Shengyong Wu Guangming Lu Department of medical Imaging Jinling Hospital Clinical school of medical College Nanjing university Nanjing Jiangsu(210002) china tianjin medical Imaging Institute

PURPOSE To investigate the feasibility of epigastrium dual-energy virtual non contrast CT(VNCT) of dual source CT(DSCT). METHOD AND MATERIALS From February to March 2009,46 patients who were suspected with intrahepatic lesions in our hospital were referred to perform abdominal CT scan(DSCT,SOMATOM Definition, Siemens medical Solutions,Germany).Conventional(CNCT),arterial and portal phase enhanced scanning were

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我国优秀女子三级跳远运动员技术指标分析

体育学刊 2003年第5期10卷 131-134页

作者：金宗强姜卫芬北京体育大学研究生院北京100084 天津医科大学体育部天津300070

采用技术动作摄像法、解析法和数理统计法,对我国8名优秀女子三级跳远运动员的若干技术指标进行了诊断分析,结果表明她们的技术类型属平衡式技术,上板速度与世界优秀运动员相比存在明显差距,不过速度利用率较高。建议今后运用速度利用... 详细信息

采用技术动作摄像法、解析法和数理统计法,对我国8名优秀女子三级跳远运动员的若干技术指标进行了诊断分析,结果表明她们的技术类型属平衡式技术,上板速度与世界优秀运动员相比存在明显差距,不过速度利用率较高。建议今后运用速度利用率和轨迹利用率指标对三级跳远运动员进行技术评估。

关键词：优秀女子运动员三级跳远技术指标中国