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Journal of Materials Science and Chemical Engineering 2023年第7期11卷 20-30页

作者： Nguyen Thi Tuyet Mai Nguyen Thi Lan Trinh Xuan Anh Ta Ngoc Dung huynh dang chinh School of Chemical Engineering Hanoi University of Science and Technology Hanoi Vietnam

In this experiment, Cu2+ doped ZnO (Cu-ZnO) nanorods materials have been fabricated by hydrothermal method. Cu2+ ions were doped into ZnO with ratios of 2, 5 and 7 mol.% (compared to the mole’s number of Zn2+). The hexamethylenetetramine (HMTA) solvent used for the fabrication of Cu-ZnO nanorods with the mole ratio of Zn2+:HMTA = 1:4. The characteristics of the materials were analyzed by techniques, such as XRD, Raman shift, SEM and UV-vis diffuse reflectance spectra (DRS). The photocatalytic properties of the materials were investigated by the decomposition of the methylene blue (MB) dye solution under ultraviolet light. The results show that the size of Cu-ZnO nanorods was reduced when the Cu2+ doping ratio increased from 2 mol.% to 7 mol.%. The decomposition efficiency of the MB dye solution reached 92% - 97%, corresponding to the Cu2+ doping ratio changed from 2 - 7 mol.% (after 40 minutes of ultraviolet irradiation). The highest efficiency for the decomposition of the MB solution was obtained at a Cu2+ doping ratio of 2 mol.%.

关键词： Cu2+ Doped ZnO Nanorods ZnO Nanomaterials Hexamethylenetetramine (HMTA) Photocatalytics Methylene Blue Hydrothermal Method UV Irradiation

Effect of Freeze-Thaw and Urea in Solubility of GPC3-Csub Protein Expressed in Escherichia coli

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Journal of Biosciences and Medicines 2024年第4期12卷 288-297页

作者： Xuan-Truc Chu-Dao Kim-Tuyen huynh-Dam dang-Thuc Ngo-Luong Quang-Luan Le Thanh-Thao Vo-Nguyen Department of Medical Biotechnology Biotechnology Center of Ho Chi Minh City Ho Chi Minh City Vietnam

Glypican-3 is a protein encoded by the Glypican-3 gene located on human X chromosome (Xq26), composed of two subunits, a 40 kDa N-terminal subunit, and a 30 kDa C-terminal subunit. Glypican-3 is a currently potential target molecule for liver cancer treatments because of its over-expression and growth effects on hepatocellular carcinoma (HCC). This study examined the expression and purification of a C-terminal subunit of Glypican-3 protein (GPC3-Csub) due to its application in both diagnosis and therapy for hepatocellular carcinoma. The gene encoding for GPC3-Csub was successfully cloned into plasmid pET28a fused with an affinity tag composed of six consecutive histidine residues (His-tag). Recombinant protein GPC3-Csub was expressed in Escherichia coli BL21 (DE3) in the condition of adding 3% ethanol with IPTG induction. GPC3-Csub was extracted using repeated freeze-thaw cycles with lysozyme, and inclusion bodies were solubilized by 8M Urea, SDS 10% in pH 12. His-tag fused GPC3-Csub proteins allowed it to be purified by affinity chromatography method using the Nickel-nitrilotriacetic acid (Ni-NTA) column. High expression of GPC3-Csub was confirmed by Coomassie staining and western-blot. GPC3-Csub could be isolated with a Ni-NTA column and have a purity of about 90%.

关键词： Glypican-3 Affinity Chromatography Inclusion Body Liver Cancer

Is convenience really king? Comparative evaluation of catastrophic costs due to tuberculosis in the public and private healthcare sectors of Viet Nam: a longitudinal patient cost study

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贫困所致传染病(英文) 2024年第2期13卷 17-28页

作者： Nguyen Hoa Binh Quang Vo Luan Nguyen Forse Rachel Jeanette Wiemers Anja Maria Christine huynh Huy Ba Dong Thuy Thi Thu Phan Yen Thi Hoang Creswell Jacob dang Thi Minh Ha Nguyen Lan Huu Shedrawy Jad L?nnroth Knut Nguyen Tuan Dinh Van Dinh Luong Annerstedt Kristi Sidney Codlin Andrew James National Lung Hospital Ha Noi Viet Nam Friends for International TB Relief Ha Noi Viet Nam Department of Global Public Health WHO Collaboration Centre On Tuberculosis and Social Medicine Karolinska Institute Stockholm Sweden Stop TB Partnership Geneva Switzerland Pham Ngoc Thach Hospital Ho Chi Minh City Viet Nam

Background In Viet Nam, tuberculosis (TB) represents a devastating life-event with an exorbitant price tag, partly due to lost income from daily directly observed therapy in public sector care. Thus, persons with TB may seek care in the private sector for its flexibility, convenience, and privacy. Our study aimed to measure income changes, costs and catastrophic cost incurrence among TB-affected households in the public and private *** Between October 2020 and March 2022, we conducted 110 longitudinal patient cost interviews, among 50 patients privately treated for TB and 60 TB patients treated by the National TB Program (NTP) in Ha Noi, Hai Phong and Ho Chi Minh City, Viet Nam. Using a local adaptation of the WHO TB patient cost survey tool, participants were interviewed during the intensive phase, continuation phase and post-treatment. We compared income levels, direct and indirect treatment costs, catastrophic costs using Wilcoxon rank-sum and chi-squared tests and associated risk factors between the two cohorts using multivariate *** The pre-treatment median monthly household income was significantly higher in the private sector versus NTP cohort (USD 868 vs USD 578;P=0.010). However, private sector treatment was also significantly costlier (USD 2075 vs USD 1313;P=0.005), driven by direct medical costs which were 4.6 times higher than costs reported by NTP participants (USD 754 vs USD 164;P<0.001). This resulted in no significant difference in catastrophic costs between the two cohorts (Private: 55% vs NTP: 52%;P=0.675). Factors associated with catastrophic cost included being a single-person household [adjusted odds ratio [(aOR=13.71; 95% confidence interval (CI): 1.36–138.14;P=0.026], unemployment during treatment (aOR=10.86; 95%CI: 2.64–44.60;P<0.001) and experiencing TB-related stigma (aOR=37.90; 95%CI: 1.72–831.73;P=0.021).Conclusions Persons with TB in Viet Nam face similarly high risk of catastrophic costs whether treated in the

关键词： Tuberculosis Patient cost Catastrophic cost Private sector Comparative analysis Viet Nam

Fresh and hardened properties of high-performance fiber-reinforced concrete containing fly ash and rice husk ash:Influence of fiber type and content

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Frontiers of Structural and Civil Engineering 2022年第12期16卷 1621-1632页

作者： Nguyen-Trong HO Viet Quoc dang Minh-Hieu NGUYEN Chao-Lung HWANG Trong-Phuoc huynh Faculty of Civil Engineering VSB-Technical University of OstravaOstrava-Poruba 70800Czech Republic Faculty of Bridge and Road Construction Mientrung University of Civil Engineering(MUCE)Tuy Hoa City 56100Vietnam Vinh Long Department of Construction Vinh Long City 85000Vietnam Taiwan Building Technology Center Taiwan University of Science and TechnologyTaipei 10607China Faculty of Civil Engineering College of EngineeringCan Tho UniversityCan Tho City 94000Vietnam

Although fibers are used only infrequently as an additive in concrete in the construction industry,fiberenhanced concrete is known to provide a wide range of advantages over conventional *** main objective of this study was to investigate the influences of fiber type and content on the mechanical properties and durability of highperformance fiber-reinforced concrete(HPFRC)designed using a novel densified mixture design algorithm with fly ash and rice husk *** types of fiber,including polypropylene(PP)fiber,steel fiber(SF),and hybrid fiber(HF),were *** on the results,the inclusion of fibers decreased HPFRC flowability,regardless of fiber *** the compressive strength of HPFRC with 1.6%PP fiber content was 11.2%below that of the reference HPFRC specimen at 91 d of curing age,the 91-d compressive strengths of both SF and HF-enhanced HPFRC specimens were significantly better than that of the reference HPFRC ***,the HPFRC specimens incorporating SF and HF both exhibited better splitting tensile and flexural strengths as well as less drying shrinkage than the HPFRC specimens incorporating PP ***,the fiber-enhanced specimens,especially those with added SF,registered less surface electrical resistivity and greater vulnerability to chloride ion penetration than the reference HPFRC specimen.

关键词： high-performance fiber-reinforced concrete fly ash rice husk ash durability mechanical strength

Deep Learning Based Optimal Multimodal Fusion Framework for Intrusion Detection Systems for Healthcare Data

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Computers, Materials & Continua 2021年第3期66卷 2555-2571页

作者： Phong Thanh Nguyen Vy dang Bich huynh Khoa dang Vo Phuong Thanh Phan Mohamed Elhoseny Dac-Nhuong Le Department of Project Management Ho Chi Minh City Open UniversityHo Chi Minh City700000Vietnam Department of Learning Material Ho Chi Minh City Open UniversityHo Chi Minh City700000Vietnam Faculty of Computers and Information Mansoura UniversityDakahlia Governorate35516Egypt Institute of Research and Development Duy Tan UniversityDanang550000Vietnam Faculty of Information Technology Duy Tan UniversityDanang550000Vietnam

Data fusion is a multidisciplinary research area that involves different *** is used to attain minimum detection error probability and maximum reliability with the help of data retrieved from multiple healthcare *** generation of huge quantity of data from medical devices resulted in the formation of big data during which data fusion techniques become *** medical data is a crucial issue of exponentially-pacing computing world and can be achieved by Intrusion Detection Systems(IDS).In this regard,since singularmodality is not adequate to attain high detection rate,there is a need exists to merge diverse techniques using decision-based multimodal fusion *** this view,this research article presents a new multimodal fusion-based IDS to secure the healthcare data using *** proposed model involves decision-based fusion model which has different processes such as initialization,pre-processing,Feature Selection(FS)and multimodal classification for effective detection of *** FS process,a chaotic Butterfly Optimization(BO)algorithmcalled CBOA is *** the classic BO algorithm offers effective exploration,it fails in achieving faster *** order to overcome this,i.e.,to improve the convergence rate,this research work modifies the required parameters of BO algorithm using chaos ***,to detect intrusions,multimodal classifier is applied by incorporating three Deep Learning(DL)-based classification ***,the concepts like Hadoop MapReduce and Spark were also utilized in this study to achieve faster computation of big data in parallel computation *** validate the outcome of the presented model,a series of experimentations was performed using the benchmark NSLKDDCup99 Dataset *** proposed model demonstrated its effective results on the applied dataset by offering the maximum accuracy of 99.21%,precision of 98.93%and detection rate of 99.59%.The results assured the betterm

关键词： Big data data fusion deep learning intrusion detection bio-inspired algorithm spark

An Optimal Deep Learning Based Computer-Aided Diagnosis System for Diabetic Retinopathy

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Computers, Materials & Continua 2021年第3期66卷 2815-2830页

作者： Phong Thanh Nguyen Vy dang Bich huynh Khoa dang Vo Phuong Thanh Phan Eunmok Yang Gyanendra Prasad Joshi Department of Project Management Ho Chi Minh City Open UniversityHo Chi Minh City7000000Vietnam Department of Learning Material Ho Chi Minh City Open UniversityHo Chi Minh City7000000Vietnam Department of Convergence Science Kongju National UniversityGongju32588South Korea Department of Computer Science and Engineering Sejong UniversitySeoul05006South Korea

Diabetic Retinopathy(DR)is a significant blinding disease that poses serious threat to human vision *** and severity grading of DR are difficult processes to ***,it depends on ophthalmoscopically-visible symptoms of growing severity,which is then ranked in a stepwise scale from no retinopathy to various levels of DR *** paper presents an ensemble of Orthogonal Learning Particle Swarm Optimization(OPSO)algorithm-based Convolutional Neural Network(CNN)Model EOPSO-CNN in order to perform DR detection and *** proposed EOPSO-CNN model involves three main processes such as preprocessing,feature extraction,and *** proposed model initially involves preprocessing stage which removes the presence of noise in the input ***,the watershed algorithm is applied to segment the preprocessed *** by,feature extraction takes place by leveraging EOPSO-CNN ***,the extracted feature vectors are provided to a Decision Tree(DT)classifier to classify the DR *** study experiments were carried out using Messidor DR Dataset and the results showed an extraordinary performance by the proposed method over compared methods in a considerable *** simulation outcome offered the maximum classification with accuracy,sensitivity,and specificity values being 98.47%,96.43%,and 99.02%respectively.

关键词： Diabetic retinopathy convolutional neural network classification image processing computer-aided diagnosis

CONVERGENCE RESULTS FOR NON-OVERLAP SCHWARZ WAVEFORM RELAXATION ALGORITHM WITH CHANGING TRANSMISSION CONDITIONS

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Acta Mathematica Scientia 2022年第1期42卷 105-126页

作者： Minh-Phuong TRAN Thanh-Nhan NGUYEN Phuoc-Toan huynh Nhu-Binh LY Minh-dang NGUYEN Quoc-Anh HO Applied Analysis Research Group Faculty of Mathematics and StatisticsTon Duc Thang UniversityHo Chi Minh cityVietnam Department of Mathematics Ho Chi Minh City University of EducationHo Chi Minh cityVietnam Faculty of Mathematics and Statistics Ton Duc Thang UniversityHo Chi Minh cityVietnam

In this paper,we establish a new algorithm to the non-overlapping Schwarz domain decomposition methods with changing transmission conditions for solving one dimensional advection reaction diffusion *** precisely,we first describe the new algorithm and prove the convergence results under several natural assumptions on the sequences of parameters which determine the transmission *** we give a simple method to estimate the new value of parameters in each *** interesting advantage of our method is that one may update the better parameters in each iteration to save the computational cost for optimizing the parameters after many *** some numerical experiments are performed to show the behavior of the convergence rate for the new method.

关键词： domain decomposition method Schwarz waveform relaxation algorithm advection reaction diffusion changing transmission conditions

Biomass accumulation of Panax vietnamensis in cell suspension cultures varies with addition of plant growth regulators and organic additives

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Asian Pacific Journal of Tropical Medicine 2017年第9期10卷 907-915页

作者： Tuan Tran Trong Dieu-Hien Truong Hoang chinh Nguyen Dieu-Thai Tran Huyen-Trang Nguyen Thi Giap Do dang Ho Nguyen Huu Plant Cell Technology Department Institute of Tropical BiologyVietnam Academy of Science and Technology9/621 Ha Noi HighwayLinh TrungThu DucHo Chi Minh CityViet Nam Faculty of Applied Sciences Ton Duc Thang University19 Nguyen Huu ThoTan PhongDistrict 7Ho Chi Minh CityViet Nam Genetic Engineering Department Institute of Tropical BiologyVietnam Academy of Science and Technology9/621 Ha Noi HighwayLinh TrungThu DucHo Chi Minh CityViet Nam

Objective: To evaluate the impact of plant growth regulators including kinetin(KN),benzyl adenine and naphthalene acetic acid, yeast extract and casein hydrolyzate on biomass accumulation of Vietnamese ginseng Panax vietnamensis(P. vietnamensis) in cell suspension ***: Cell suspension cultures were established from friable calluses derived from leaves and petioles of 3-year-old in-vitro P. vietnamensis plants. The cell suspension cultures were grown in Murashige and Skoog basal media supplemented with various concentrations of KN, benzyl adenine, naphthalene acetic acid, and yeast extract and casein ***: All tested factors generated an increase in the cell biomass of P. vietnamensis in suspension culture, but the impact of each varies depended on the factor type, concentration, and incubation period. Addition of 2.0 mg/L KN resulted in the largest biomass increase after 24 d,(57.0 ± 0.9) and(3.1 ± 0.1) mg/m L fresh and dry weight, respectively,whereas addition of benzyl adenine or naphthalene acetic acid produced optimum levels of Panax cell biomass at 1.0 and 1.5 mg/L, respectively. Addition of the elicitor yeast extract led to a 1.4–2.4 fold increase in biomass of P. vietnamensis, while addition of casein hydrolyzate enhanced biomass accumulation 1.8–2.6 ***: The addition of each factor causes significant changes in biomass accumulation of P. vietnamensis. The largest biomass accumulation is from cultures grown in MS media containing 2.0 mg/L KN for 24 d. The outcome of the present study provides new insights into the optimal suspension culture conditions for studies on the in vitro cell biomass production of P. vietnamensis.

关键词： Panax vietnamensis Plant cell suspension culture Plant regulators Yeast extract Casein hydrolyzate Biomass

Antibiotic usage in surgical sperm retrievals among IVF centers

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Asian Journal of Andrology 2022年第6期24卷 633-638页

作者： Le dang Khoa Ngo Dinh Trieu Vy Nguyen Minh Tai Loc Le Duc Thang dang Tuan Anh Nguyen Phuc Hieu Giang huynh Nhu Nguyen Dinh Tao Le Hoang David J Handelsman IVFTA Tam Anh General HospitalHo Chi Minh 700000Vietnam IVFTA Tam Anh General HospitalHa Noi 100000Vietnam IVF Center 16A Ha Dong HospitalHa Noi 100000Vietnam ANZAC Research Institute University of Sydney and Concord Repatriation General HospitalHospital RoadConcordNSW 2139Australia

Surgical sperm retrieval(SSR)is currently one of the most common procedures in in vitro fertilization(IVF).However,a gap between the guidelines and routine clinical practice regarding antibiotic use in sSR,which might lead to antibiotic resistance,is a challenging problem worldwide.A cross-sectional survey was conducted from May 1,2021,to July 15,2021,to investigate antibiotic usage by medical professionals when performing SSR in IVF centers in *** confidential questionnaire comprised 12 items,including characteristics of the study population,awareness of antimicrobial resistance,attitude toward prescribing antibiotics,and current practice of prescribing antibiotics when performing *** were completed by 30 of 45 registered IVF centers(66.7%).Among 67 physicians working at those centers,the age and work-experience years(mean±standard deviation[s.d.])were 38.6±6.6 years and 11.2±7.0 years,*** 60%of them held a degree in Obstetrics and Gynecology,and over four-fifths were *** respondents"often/very often/always"raised awareness of antimicrobial resistance to their patients(83.3%),but only half of them"often/occasionally"prescribed antibiotics to patients with SSR in cases where the prescription would be *** one-tenth of respondents followed the recommendation from the American Urological Association using"prophylaxis only"for SSR *** more invasive SSR,physicians tended to prescribe more complicated and sometimes inappropriate *** conclusion,antibiotic usage in SSR was not always appropriate among IVF *** studies may define specific recommendations for regimens,intervention strategies,and programs to promote appropriate antibiotic use for SSR patients among IVF specialists.

关键词： antibiotic usage in vitro fertilization prophylaxis surgical sperm retrieval treatment

Hepatitis B vaccination status and associated factors among health science students

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Asian Pacific Journal of Tropical Medicine 2023年第5期16卷 213-219页

作者： Binh Thanh Nguyen Lan Y Vo Tap Van Nguyen Minh Cong Vo Tinh dang Pham Han Thi Ngoc Nguyen Lynda Boyer-Chu Giao huynh Faculty of Medicine Tra Vinh UniversityTra Vinh CityTra Vinh ProvinceVietnam Faculty of Public Health University of Medicine and Pharmacy at Ho Chi Minh CityHo Chi Minh CityVietnam Faculty of Medical Management Nguyen Tat Thanh UniversityHo Chi Minh CityVietnam Department of Ear Nose Throat-Head and Neck Surgery FV hospitalHo Chi Minh CityVietnam Department of Anaesthesia and Intensive Care FV hospitalHo Chi Minh CityVietnam Infection Control Department University Medical Center Ho Chi Minh CityHo Chi Minh CityVietnam San Francisco Unified School District San FranciscoCaliforniaUSA

Objective:To evaluate hepatitis B virus(HBV)vaccine coverage and its associated factors among health science students in ***:This cross-sectional study involving 459 health science students at Tra Vinh University was conducted between April and June *** were collected using a structured questionnaire with items on sociodemographic characteristics,knowledge and attitude about HBV,and vaccination status.A multivariable logistic regression model was used to explore the factors associated with vaccination ***:The majority of participants were female(65.8%)and enrolled at the medical school(56.2%).A total of 30.3%participants received the full dose of the HBV *** percentages of participants with sufficient knowledge and positive attitudes toward HBV infection were 75.2%and 43.4%,*** was 11.8 times higher in sixth-year medical students than any healthcare student in their first-year[adjusted odds ratio(aOR)11.8,95%CI 3.1-45.1,P<0.001],and the coverage was also significant higher in those who had sufficient knowledge(aOR 2.0,95%CI 1.1-3.9,P<0.05)and positive attitudes(aOR 3.0,95%CI 1.9-4.8,P<0.05)than in their ***:The majority of students were not fully vaccinated against HBV,indicating they were vulnerable to the *** and authorities should reinforce health education messages aimed at encouraging all students to get vaccinated with the HBV vaccine,enhance their awareness and knowledge of HBV,and improve attitudes toward HBV infection prevention.

关键词： Hepatitis B Knowledge Attitude Practice Vaccination Students