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Cronkhite-Canada syndrome:First case report from Egypt and North Africa

World Journal of Gastrointestinal Endoscopy 2022年第10期14卷 642-647页

作者： Ahmed elsayed Alzamzamy Ashraf Aboubakr hussein H Okasha Abeer Abdellatef Shaimaa Elkholy Mahmoudd Wahba Mohamed Alboraie hussein elsayed Mohamed O Othman Department of Gastroenterology and Hepatology Maadi Armed Forces Medical ComplexMilitary Medical AcademyCairo 11711Egypt Department of Internal Medicine Division of GastroenterologyHepatology and EndoscopyCairo UniversityCairo 11311Egypt Department of Internal Medicine Al-Azhar UniversityCairo 11311Egypt Department of Pathology Military Medical AcademyCairo 11711Egypt Department of Internal Medicine Baylor College of MedicineHoustonTX 77082United States

BACKGROUND Gastrointestinal(GI)polyposis is a rare condition in GI *** date about 500 cases of Cronkhite-Canada syndrome(CCS)have been reported *** SUMMARY We report a 60-year-old female patient who presented with dyspepsia,abdominal pain,and weight loss of 1-year *** physical examination showed alopecia and *** endoscopy revealed diffuse markedly thickened gastric mucosa involving the whole stomach with thickened gastric rugae and numerous polypoidal *** examination showed marked hyperplasia of the foveolar glands with inflammatory cell *** ultrasound showed a significantly hypertrophic mucosa and muscularis mucosa,while the submucosa and the muscularis propria were spared,favouring its benign *** showed multiple sessile polyps scattered at different parts of the *** examination revealed tubular adenomatous polyps with low-grade *** diagnoses included CCS,Menterier disease(MD),other polyposis syndromes,lymphoma,amyloidosis,and gastric *** presence of alopecia,nail dystrophy,GI polyposis,markedly thickened gastric mucosa and folds,abdominal pain,weight loss,and marked foveolar gland hyperplasia;all was in favour of *** was excluded due to sparing of the muscularis *** presence of colonic polyps and antral and duodenal infiltration,and the absence of hypoproteinaemia decreased the possibility for *** The patient was diagnosed as having CCS.

关键词： Gastrointestinal polyposis Thickened gastric mucosa Cronkhite-Canada syndrome Case report

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Impact of carbimazole combined with vitamin E on testicular injury induced by experimental hyperthyroidism in adult albino rats:oxidative/inflammatory/apoptotic pathways

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Asian Journal of Andrology 2024年第4期26卷 396-401页

作者： Ramadan S hussein Moustafa M Eyada Rashad M Mostafa Samah M Elaidy Shereen H elsayed Hany M Saad Department of Dermatology College of Medicine Prince Sattam Bin Abdulaziz UniversityAl-Kharj 16242Saudi Arabia Department of Dermatology Andrology and STDsAssiut Police HospitalAssiut 71525Egypt Department of Dermatology Venereology and AndrologyFaculty of MedicineSuez Canal UniversityIsmailia 41522Egypt Department of Andrology and Sexology Faculty of MedicineSuez Canal UniversityIsmailia 41511Egypt Department of Clinical Pharmacology Faculty of MedicineSuez Canal UniversityIsmailia 41511Egypt Department of Rehabilitation Sciences Faculty of Health and Rehabilitation SciencesPrincess Nourah bint Abdulrahman UniversityRiyadh 12271Saudi Arabia.

Thyroid hormones play essential roles in spermatogenesis,but their effects on infertile males remain poorly *** study aimed to evaluate the impact of combining carbimazole(CBZ)with vitamin E(VE)on testicular injury induced by experimental hyperthyroidism in adult albino rats,focusing on oxidative,inflammatory,and apoptotic *** this experimental study,64 adult male albino Wistar rats were divided into eight groups:Group I(control-untreated),Group II(CBZ-control),Group III(VE-control),Group IV(CBZ+VE-control),Group V(levothyroxine-induced testicular injury),Group VI(levothyroxine+CBZ-treated),Group VII(levothyroxine+VE-treated),and Group VIII(levothyroxine+CBZ+VE-treated).The study was conducted in the Faculty of Medicine,Suez Canal University(Ismailia,Egypt).After cervical decapitation,both testes and epididymis were examined histopathologically and *** differences were observed among groups concerning malondialdehyde(MDA),glutathione(GSH),superoxide dismutase(SOD),and catalase(CAT;all P<0.001).Polymerase chain reaction analysis showed significant differences in tumor necrosis factor-α(TNF-α),interleukin-10(IL-10),Bcl-2-associated X protein(BAX),B-cell lymphoma 2 protein(Bcl2),p53,Caspase-3,Caspase-8,Caspase-9,and nuclear factor-kappa B(NF-κB)mRNA levels(all P<0.001).Hyperthyroid group treated with CBZ alone(Group VI)exhibited testicular side effects,affecting seminiferous tubules and ***,the Group VIII showed improved spermatogenesis and a decrease in testicular side *** addition of VE to the treatment of hyperthyroid rats with CBZ reduced testicular side effects and seminiferous tubular affection when potentially improving *** research is needed to elucidate the underlying mechanisms fully.

关键词： antithyroid drugs testicular injury thyroid gland vitamin E

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Near-zero stiffness accelerometer with buckling of tunable electrothermal microbeams

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Microsystems & Nanoengineering 2024年第2期10卷 67-81页

作者： hussein hussein Chen Wang Rui Amendoeira Esteves Michael Kraft Hossein Fariborzi Department of Mechanical Engineering MSFEAAmerican University of BeirutBeirut11072020Lebanon King Abdullah University of Science and Technology Thuwal23955-6900Saudi Arabia ESAT-MNS University of Leuven3001LeuvenBelgium

Pre-shaped microbeams,curved or inclined,are widely used in MEMS for their interesting stiffness *** mechanisms allow a wide range of positive and negative stiffness tuning in their direction of motion.A mechanism of pre-shaped beams with opposite curvature,connected in a parallel configuration,can be electrothermally tuned to reach a near-zero or negative stiffness behavior at the as-fabricated *** simple structure helps incorporate the tunable spring mechanism in different designs for accelerometers,even with different transduction *** sensitivity of the accelerometer can be considerably increased or tuned for different applications by electrothermally changing the stiffness of the spring *** inclined beams are implemented in a capacitive micromachined *** measurements on fabricated prototypes showed more than 55 times gain in sensitivity compared to their initial *** experiments showed promising results in enhancing the resolution of acceleration sensing and the potential to reach unprecedent performance in micromachined accelerometers.

关键词： properties. mechanism. stiffness

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A reinforcement learning approach for thermostat setpoint preference learning

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Building Simulation 2024年第1期17卷 131-146页

作者： hussein Elehwany Mohamed Ouf Burak Gunay Nunzio Cotrufo Jean-Simon Venne Department of Environmental Engineering Carleton UniversityOttawaCanada Departmentof Building Civiland Environmental EngineeringConcordia UniversityMontrealCanada BrainBox Al Inc. MontrealCanada

Occupant-centric controls(OcC)is an indoor climate control approach whereby occupant feedback is used in the sequence of operation of building energy *** OcC has been used in a wide range of building applications,an OcC category that has received considerable research interest is learning occupants'thermal preferences through their thermostat interactions and adapting temperature setpoints *** recent studies used reinforcement learning(RL)as an agent for OcC to optimize energy use and occupant *** studies depended on predicted mean vote(PMV)models or constant comfort ranges to represent comfort,while only few of them used thermostat *** paper addresses this gap by introducing a new off-policy reinforcement learning(RL)algorithm that imitates the occupant behaviour by utilizing unsolicited occupant thermostat *** algorithm is tested with a number of synthetically generated occupant behaviour models implemented via the Python APl of *** simulation results indicate that the RL algorithm could rapidly learn preferences for all tested occupant behaviour scenarios with minimal exploration *** substantial energy savings were observed with most occupant scenarios,the impact on the energy savings varied depending on occupants'preferences and thermostat use behaviour stochasticity.

关键词： reinforcement learning preference learning occupant-centric controls smart thermostats off-policy learning

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Novel design of a compact tunable dual band wireless power transfer(TDB-WPT)system for multiple WPT applications

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Frontiers of Information Technology & Electronic Engineering 2024年第4期25卷 616-628页

作者： Hany A.ATALLAH Rasha hussein AHMED Adel B.ABDEL-RAHMAN Department of Communications and Electronics Faculty of EngineeringSouth Valley UniversityQena 83523Egypt Egypt-Japan University of Science and Technology Alexandria 21934Egypt

In this study we present the design and realization of a tunable dual band wireless power transfer(TDB-WPT)coupled resonator *** frequency response of the tunable band can be controlled using a surface-mounted *** transmitter(Tx)and the receiver(Rx)circuits are *** top layer contains a feed line with an impedance of 50Ω.Two identical half rings defected ground structures(HR-DGSs)are loaded on the bottom using a varactor *** propose a solution for restricted WPT systems working at a single band application according to the operating *** effects of geometry,orientation,relative distance,and misalignments on the coupling coefficients were *** validate the simulation results,the proposed TDB-WPT system was fabricated and *** system occupied a space of 40 mm×40 *** can deliver power to the receiver with an average coupling efficiency of 98%at the tuned band from 817 to 1018 MHz and an efficiency of 95%at a fixed band of 1.6 GHz at a significant transmission distance of 22 *** results of the measurements accorded well with those of an equivalent model and the simulation.

关键词： Defected ground structure(DGS) Surface-mounted Tunable dual band wireless power transfer(TDB-WPT) Varactor

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Does local vaginal estrogen after tension-free transobturator vaginal tape reduce overactive bladder symptoms in postmenopausal women? A prospective randomized, controlled study

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Asian Journal of Urology 2024年第1期11卷 86-92页

作者： Samer Mahmoud Morsy Dalia Farouk Sara Hassan Ahmed Yehia Abdelaziz hussein Aly hussein Urology Department Kasr Al Ainy HospitalCairo UniversityCairoEgypt Obstetrics and Gynecology Department Kasr Al Ainy HospitalCairo UniversityCairoEgypt

Objective:We aimed to evaluate the efficacy of topical estrogen after transvaginal tension-free vaginal tape-obturator(TVT-O)in the treatment of de novo overactive bladder symptoms that appear after ***:This is a prospective randomized controlled study performed in the Urology and Gynecology Departments,Kasr Al Ainy Hospital,Cairo University,Cairo,*** hundred and ten postmenopausal females presenting during the period between January 2017 and November 2020 with stress urinary incontinence were included in the *** were divided into two groups,105 patients in Group A(treatment group)and 105 patients in Group B(control group).Patients in Group A underwent transvaginal TVT-O followed by local vaginal estrogen treatment for 6 months,while patients in Group B underwent transvaginal TVT-O *** study included any postmenopausal female with urodynamic stress urinary *** patients had to fulfill a 3-day bladder diary,overactive bladder symptoms score,urine analysis,urodynamic study,and post-voiding residual urine measurement by abdominal ultrasound preoperatively and at 3-month and 6-month ***:At 6-month follow-up,daytime frequency was reduced to 8%in Group A(increased to 21%in Group B)with a statistically significant difference between both groups(p=0.009).At 6-month follow-up,nocturia was 8%in Group A(11%in Group B)with no statistically significant difference between both groups(p=0.469).There was a statistically significant difference between both groups as regards to urinary urgency at 6-month follow-up(p=0.024).There was a statistically significant difference in postoperative wound healing events as regards to cure,hyperemia,gapping,and wound infection 1 week after intervention between both groups(p=0.008).No local or systemic side-effects were reported from local estrogen ***:Local vaginal estrogen treatment given to postmenopausal patients after midurethral sling procedures can reduce the symptoms o

关键词： Stressurinary incontinence Estrogen Midurethral sling Overactive bladder symptom

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Cellular preconditioning and mesenchymal stem cell ferroptosis

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World Journal of Stem Cells 2024年第2期16卷 64-69页

作者： Doaa hussein Zineldeen Mazhar Mushtaq Khawaja Husnain Haider Basic Sciences Sulaiman AlRajhi UniversityAlbukairiyah 52736AlQaseemSaudi Arabia Department of Medical Biochemistry and Molecular Biology Faculty of MedicineTanta UniversityTanta 6632110Egypt

In this editorial,we comment on the article published in the recent issue of the World Journal of Stem *** focus on stem cell preconditioning to prevent ferroptosis by modulating the cystathionineγ-lyase/hydrogen sulfide(H_(2)S)pathway as a novel approach to treat vascular disorders,particularly pulmonary *** stem cells are gaining popularity in regenerative medicine due to their unique ability to survive by resisting the harsh,unfavorable microenvironment of the injured *** also secrete various paracrine factors against apoptosis,necrosis,and ferroptosis to enhance cell ***,a regulated form of cell death characterized by iron accumulation and oxidative stress,has been implicated in various pathologies encompassing dege-nerative disorders to *** lipid peroxidation cascade initiates and sustains ferroptosis,generating many reactive oxygen species that attack and damage multiple cellular *** these intertwined mechanisms provi-des significant insights into developing therapeutic modalities for ferroptosis-related *** editorial primarily discusses stem cell preconditioning in modulating ferroptosis,focusing on the cystathionase gamma/H_(2)S ferroptosis *** presents a significant challenge in mesenchymal stem cell(MSC)-based therapies;hence,the emerging role of H_(2)S/cystathionase gamma/H_(2) S signaling in abrogating ferroptosis provides a novel option for therapeutic *** research into understanding the precise mechanisms of H_(2)S-mediated cytoprotection against ferroptosis is warranted to enhance the thera-peutic potential of MSCs in clinical settings,particularly vascular disorders.

关键词： Cell survival Cell therapy Hydrogen sulfide Ferroptosis Preconditioning Stem cells Umbilical cord

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Tuning the optoelectronic properties for small organic compounds as organic solar cell applications

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Optoelectronics Letters 2024年第7期20卷 412-417页

作者： hussein K.Mejbel Lafy F.Al-Badry Department of Physics College of Education for Pure Science University of Thi-Qar Department of Physics College of Science University of Thi-Qar

Recently, organic solar cells have attracted the attention of many researchers owing to flexibility, low cost, light weight and large-area applications, and significant improvement in the power conversion efficiency（PCE）. In this work, we designed chains from organic compounds as donors and replaced the core unit in each series with a variety of acceptors in order to enhance their optical and electronic characterization and performance for power conversion efficiencies in organic solar cells. We utilized density functional theory（DFT） and time-dependent density functional theory（TD-DFT） to investigate the geometry optimization by using the Gaussian 09 program. Both electronic and optical properties were determined, which involve the lowest unoccupied molecular orbital（LUMO） and the highest occupied molecular orbital（HOMO） levels, the band gap energy, maximum absorption wavelength(λ;max;), open circuit voltage(V;oc;), and light harvesting efficiency（LHE）. Our evaluation denotes that the small compounds suggested are predicted to exhibit the best performance compared to the first series（SC1）, like a lower band gap energy, a lower HOMO energy level, a greater absorption range, and a larger PCE.

关键词： A

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Hepatic recompensation according to Baveno VII criteria via transjugular intrahepatic portosystemic shunt

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World Journal of Gastroenterology 2024年第12期30卷 1777-1779页

作者： Hossam Eldin Shaaban Abeer Abdellatef hussein Hassan Okasha Department of Internal Medicine and Gastroenterology NHTMRICairo 11796Egypt Department of Internal Medicine Division of Gastroenterology and HepatologyKasr Al-Aini School of MedicineCairo UniversityCairo 11562Egypt

Transjugular intrahepatic portosystemic shunt is a therapeutic modality done through interventional *** is aimed to decrease portal pressure in special situations for patients with decompensated liver disease with portal *** represents a potential addition to the therapeutic modalities that could achieve hepatic recompensation in those patients based on Baveno VII criteria.

关键词： Decompensated liver cirrhosis Hepatic recompensation Baveno VII Portal hypertension

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埃及消费者购买假冒奢侈品态度影响因素研究

埃及消费者购买假冒奢侈品态度影响因素研究

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作者： Nayera Abdelraouf elsayed hussein Elkady 哈尔滨工业大学

学位级别：硕士

在过去的几十年里,对假冒奢侈品的市场需求迅速增长。造假数量的增加使得造假问题变得极为重要。因此,本研究的目的是分析埃及消费者在埃及购买仿冒品和配件的意图的决定因素;检查埃及消费者购买和使用仿冒品的动机以及消费者对仿冒品... 详细信息

在过去的几十年里,对假冒奢侈品的市场需求迅速增长。造假数量的增加使得造假问题变得极为重要。因此,本研究的目的是分析埃及消费者在埃及购买仿冒品和配件的意图的决定因素;检查埃及消费者购买和使用仿冒品的动机以及消费者对仿冒品和奢侈品牌的反应。由于本研究的本质,本研究采用了量化研究。通过调查问卷收集量化数据。本研究调查了273人的样本。与会者完成了一个自我准备的问卷,这是通过调整现有的规模,以适应当前的研究背景。调查是通过电子邮件向居住在开罗的答卷人发送调查问卷。收集的调查数据被输入到SPSS版本25。研究假设采用多元回归分析和单因子变异数分析进行检验。在购买假冒奢侈品的动机方面,7个独立变量中的6个与消费者对假冒奢侈品的购买意愿显着相关:品牌形象、社会动机、价值意识、诚信、求新和态度。研究结果还表明,不同性别的人在态度和意图上存在不同程度的差异。特别是,女性消费者比男性消费者有更多的支持态度,因此更有意向购买这些假冒产品。原因是女性更敏感,对时尚的要求也更高。另一方面,消费者的态度和意图没有统计上的显着差异,根据他们的年龄。根据他们的月收入,在态度和购买意愿上没有统计学上的显着差异。然而,它表明,有一个统计上显着差异的品牌形象,有利于月收入低于2000埃镑的消费者。对于月收入低于2000埃镑的消费者来说,价值意识也有统计学上的显着差异。这表明,虽然假货与原货相比质量较低,但其较低的价格和略低于标准的质量意味着许多消费者认为假货物有所值。研究结果对市场营销的理论和实践具有重要的指导意义。从理论上讲,研究结果表明,TRA问题（即对假冒、社会动机的态度）和个性因素（即诚信、求新）对于理解消费者购买奢侈假冒商品的动机至关重要。此外,研究表明,假货并不影响真正奢侈品牌的认知。对于营销实践,研究帮助品牌所有者和政策制定者更好地了解是什么促使消费者购买假冒产品。这些结果可能有助于为打击造假战略提供依据。然而,购买假冒奢侈品似乎并不影响真正品牌的看法,品牌所有者应阻止购买冒牌产品出于道德或法律原因。本研究是少数从消费者的态度,购买假冒奢侈品的TRA维度和人格维度的研究之一。深入了解消费者对购买假冒产品的态度是否会产生消费者对假冒产品的忠诚度,并从消费者和企业的角度为更深入地了解假冒消费的影响提供了一个强大的知识基础。

关键词：态度仿冒奢侈品购买意向埃及

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