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Prognosis factors of advanced gastric cancer according to sex and age

World Journal of Clinical Cases 2020年第9期8卷 1608-1619页

作者： Abdulaziz Alshehri hussain alanezi Beom Su Kim Department of Gastric Surgery Ulsan University School of MedicineAsan Medical CenterSeoul 05505South Korea General Surgery Department King Fahad Military Medical ComplexDhahran 31932Saudi Arabia Department of General Surgery Northern Area Armed Forces HospitalHafar Al Batin 31991Saudi Arabia

BACKGROUND Gastric cancer has a relatively high prevalence and is one of the most common causes of cancer-related death ***,the prognosis for gastric cancer remains poor,especially in the advanced stages,despite many improvements in diagnosis and *** To evaluate the outcomes regarding advanced gastric cancer development according to sex and *** We retrospectively reviewed 2005 patients who underwent curative gastrectomy for advanced gastric cancer between 2002 and 2007 at a single Korean *** and risk factors for nodal involvement were evaluated according to sex and *** In this retrospective cohort study,we examined the cases of 2005 patients[sex,1384 men(69%),621 women(31%)]with advanced gastric *** patients’age range was 22-87 years(mean age:57.7±12.3 years),with approximately 53.3%of the patients being≤60 years *** on a Cox proportional hazards model,overall survival was independently predicted by older age,larger tumour size,lymphovascular invasion,lymph node metastasis,deeper tumour invasion,moderately-to-poorly differentiated tubular adenocarcinoma,and signet ring cell *** same model revealed that relapse-free survival was independently predicted by advanced age,larger tumour size,lymphovascular invasion,deeper tumour invasion,poorly differentiated tubular adenocarcinoma,and signet ring cell *** Among patients with advanced gastric cancer,older age independently predicted poor overall survival and relapse-free ***,there were no significant sex-based differences in relapse-free and overall survival.

关键词： Carcinoma Prognosis Gastrectomy Risk factors Age Adenocarcinoma

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