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Diabetic peripheral neuropathy and neuromodulation techniques:a systematic review of progress and prospects

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neural Regeneration Research 2025年第8期20卷 2218-2230页

作者： Rahul Mittal Keelin McKenna Grant Keith Evan McKenna Joana R.n.Lemos Jeenu Mittal Khemraj Hirani Diabetes Research Institute University of Miami Miller School of MedicineMiamiFLUSA Department of Otolaryngology University of Miami Miller School of MedicineMiamiFLUSA Herbert Wertheim college of Medicine Florida International UniversityMiamiFLUSA School of Medicine and Public Health University of WisconsinMadisonWIUSA

neuromodulation for diabetic peripheral neuropathy represents a significant area of interest in the management of chronic pain associated with this *** peripheral neuropathy,a common complication of diabetes,is characterized by nerve damage due to high blood sugar levels that lead to symptoms,such as pain,tingling,and numbness,primarily in the hands and *** aim of this systematic review was to evaluate the efficacy of neuromodulatory techniques as potential therapeutic interventions for patients with diabetic peripheral neuropathy,while also examining recent developments in this *** investigation encompassed an array of neuromodulation methods,including frequency rhythmic electrical modulated systems,dorsal root ganglion stimulation,and spinal cord *** systematic review suggests that neuromodulatory techniques may be useful in the treatment of diabetic peripheral *** the advantages of these treatments will enable physicians and other healthcare providers to offer additional options for patients with symptoms refractory to standard pharmacologic *** these efforts,we may improve quality of life and increase functional capacity in patients suffering from complications related to diabetic neuropathy.

关键词： diabetes mellitus diabetic peripheral neuropathy neuromodulation neurostimulation therapy non-pharmacological treatment pain management

Experimental study of the effect of wear parameters on the wear behavior of A356 alloy/cow horn particulate composites

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Defence Technology（防务技术） 2018年第1期14卷 77-82页

作者： b.Q.ochieze c.c.nwobi-Okoye P.n.Atamuo Lafarge Africa Plc Mfamosing Plant Department of Mechanical Engineering Chukwuemeka Odumegwu Ojukwu University

Experimental study of the effect of wear parameters on the wear behaviour of A356 alloy reinforced with cow horn particles(cHp) produced by spark plasma sintering was investigated. Experiments were conducted based on the plan of experiments generated through Taguchi's(L9) technique. Tribometer was used for the wear test and Scanning electron microscope was used to analyse the worn scar of the samples. The results shows that, A356 alloy reinforced with cHp exhibited better dry sliding wear resistance than the unreinforced alloy. Wear rate decreased as the amount of cHp reinforcement increased in the matrix. It was found that, the optimum level of the factors with minimized the wear loss were obtained at: wt%cHp(20%), applied load(10 n), sliding velocity(3 m/s) and sliding distance(2000 m). It can be seen that the wear track of the sample are(D ? 0.81 and L = 42.85 mm) and(D ? 0.54 and L= 27.03 mm) for A356 alloy and composites at optimum condition respectively. The results showed that the addition of cow horn particles as reinforcing materials in A356 alloy composites increased the wear resistance of the composites greatly.

关键词： A356alloy cow horn particles Microstructure Analysis of variance and wear behaviour

Superhydrophobic PVDF/TiO_2-SiO_2 Membrane with Hierarchical Roughness in Membrane Distillation for Water Recovery from Phenolic Rich Solution containing Surfactant

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chinese Journal of Polymer Science 2019年第6期37卷 609-616页

作者： n.Hamzah c.P.Leo b.S.Ooi School of chemical Engineering Engineering Campus Universiti Sains Malaysia

Superhydrophobic poly(vinylidene fluoride)(PVDF) membrane incorporated with nanoparticles was applied in membrane distillation to recover water from phenolic rich solution containing surfactant. The membranes coated on woven support were fabricated using phase inversion with dual bath coagulation and post-modified using silane. The membranes incorporated with TiO_2, SiO_2, or a mixture of TiO_2-SiO_2 nanoparticles achieved the water contact angle higher than 160°. The addition of TiO_2-SiO_2 mixture into PVDF matrix further enhanced the hierarchical roughness of membrane. Hence, PVDF/TiO_2-SiO_2 membrane achieved the highest permeation flux and rejected 99.9% of gallic acid in the feed(100 g/L). PVDF/TiO_2-SiO_2 membrane also maintained a relative flux(J/J0) higher than0.9 after 8 h of operation. Even with the presence of surfactant in phenolic rich solution, PVDF/TiO_2-SiO_2 membrane was able to exhibit relative flux above 0.8. The significant changes on the hydrophobicity and chemical properties of PVDF/TiO_2-SiO_2 membrane due to fouling were not observed after 50 h of static adsorption test.

关键词： Superhydrophobic PVDF nano particles Roughness Membrane distillation

Vagus nerve stimulation in intracerebral hemorrhage:the need for further research

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neural Regeneration Research 2025年第11期20卷 3213-3214页

作者： Sheharyar S.baig Ali n.Ali Arshad Majid Sheffield Institute for Translational neuroscience Division of NeuroscienceThe University of SheffieldSheffieldUK

Vagus nerve stimulation(VnS)and stroke:Stroke is the second leading cause of death and the third leading cause of disability worldwide(baig et al.,2023).There have been significant paradigm shifts in the management of acute ischemic stroke through mechanical *** chronic ischemic stroke,invasive VnS paired with rehabilitation is associated with a significant increase in upper limb motor recovery and is FDA-approved(baig et al.,2023).There are no treatments of similar efficacy in acute intracerebral hemorrhage(IcH)where several promising trials,e.g.,TIcH-2,STOP-AUST,and TRAIGE did not show improvements in functional outcomes(Puy et al.,2023).

关键词： stimulation acute

Postmortem ^(7)Li nMR analysis for assessing the reversibility of lithium metal electrodes in lithium metal batteries

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Journal of Energy chemistry 2024年第7期94卷 430-440页

作者： Jaewon baek Sunha Kim Hee-Tak Kim oc Hee Han Department of chemical&biomolecular Engineering KAISTDaejeon 34141Republic of Korea Metropolitan Seoul center Korea Basic Science InstituteSeoul 03759Republic of Korea Graduate School of Analytical Science&Technology Chungnam National UniversityDaejeon 34134Republic of Korea

Despite the proficiency of lithium(Li)-7 nMR spectroscopy in delineating the physical and chemical states of Li metal electrodes,challenges in specimen preparation and interpretation impede its *** this study,we conducted a comprehensive postmortem analysis utilizing ^(7)Li nMR,employing a stan-dard magic angle spinning probe to examine protective-layer coated Li metal electrodes and LiAg alloy electrodes against bare Li metal electrodes within Li metal batteries(LMbs).Our investigation explores the effects of sample burrs,alignment with the magnetic field,the existence of liquid electrolytes,and precycling on the ^(7)Li nMR *** contrasting nMR spectra before and after cycling,we identi-fied alterations in Li^(0) and Li^(+) signals attributable to the degradation of the Li metal *** nMR analyses decisively demonstrate the efficacy of the protective layer in mitigating dendrite and solid elec-trolyte interphase ***,we noted that Li*ions near the Li metal surface exhibit magnetic susceptibility anisotropy,revealing a novel approach to studying diamagnetic species on Li metal elec-trodes in *** study provides valuable insights and practical guidelines for characterizing distinct lithium states within LMbs.

关键词： nMR spectroscopy Lithium-7 Lithium metal battery Electrolyte Electrode-protective layer Solid electrolyte interface Magnetic susceptibility anisotropy Lithium-metal nMR signal Diamagnetic^(7)Li nMR signal

Modelling of sediment movement in the surf and swash zones

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Acta oceanologica Sinica 2015年第2期34卷 137-142页

作者： TOKPOHOZIn n.b. KOUnOUHEWA b. AVOSSEVOU G.Y.H. HOUEKPOHEHAM A. AWAnOU c.n. Institut de Mathématiques et de Sciences Physiques (IMSP/UAc) centre béninois de la Recherche Scientifique et Technique (cbRST) Laboratoire de Physique du Rayonnement (LPR/FAST-UAc)

Under the action of marine currents,non-cohesive sediments evolve by bed-load,by saltation or suspension depending on their *** authors have considered that the movement of sediment is bidimensional and modelized the effects of swell by a constant velocitynear the *** we have studied the velocity profile of fluctuating currents near the seabed and studied the movement of sediment in *** results show that in the areas of study（surf and swash）the movement of sediment occurs in a volume,and the evolution of sediment varies from an areato *** obtained theoretical profiles of the position and velocity vectors confirm the observations of several authors.

关键词： non-cohesive sediments sediment dynamics swell trajectory of sediment velocity drive

植物系统发生海报——以演化视角介绍植物多样性的科教资料项目

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生物多样性 2025年

作者：蒋陈焜郁文彬饶广远黎怀成 Julien b.bachelier Hartmut H.Hilger Theodor c.H.cole 北京大学生命科学学院蛋白质与植物基因研究国家重点实验室北京大学前沿交叉学科研究院北京大学-清华大学生命科学联合中心中国科学院西双版纳热带植物园综合保护中心/云南省热带雨林与亚洲象保护重点实验室 Dahlem centre of Plant Sciences (DcPS)， Institute of biology， Structural and Functional Plant Diversity， Freie Universit?t berlin

中国的植物多样性保护行动虽然提升了公众对多样性的认识，但这些努力往往未能深入到理解植物多样性演化及其保护的深层意义。从演化的视角进行植物多样性宣传教育，有利于促进对多样性的综合理解，增进对多样性保护的认可。然而， ... 详细信息

中国的植物多样性保护行动虽然提升了公众对多样性的认识，但这些努力往往未能深入到理解植物多样性演化及其保护的深层意义。从演化的视角进行植物多样性宣传教育，有利于促进对多样性的综合理解，增进对多样性保护的认可。然而，现有资料多集中于物种的识别、鉴定与分类，缺乏从生物演化角度对植物多样性进行系统性介绍的内容。本文介绍了一个具有全球影响力的科教资料案例——由美裔德国植物学家Theodor c. H. cole发起的植物系统发生海报(Plant Phylogeny Posters)项目。该项目通过整合最新的系统与演化植物学研究成果，以系统发生为线索介绍植物多样性及其亲缘关系，旨在利用系统发生树所蕴含的丰富演化思想内涵，启发读者理解植物多样性与演化。海报以系统发生树结合植物类群的形态、地理分布、物种数量等数据信息，直观展示了多个分类等级的重要类群的演化历史。在数十所大学和科研机构的45位研究人员的努力下， 70张系统发生海报已被翻译成中文，并向所有人免费开放获取。这一科教项目有望为增进公众深入理解植物多样性及其保护行动提供宝贵的资源和帮助。

关键词：植物多样性演化系统发生科教资料

Ultra‑Transparent and Multifunctional IZVO Mesh Electrodes for next‑Generation Flexible Optoelectronics

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nano-Micro Letters 2025年第1期17卷 293-309页

作者： Kiran A.nirmal Tukaram D.Dongale Atul c.Khot chenjie Yao nahyun Kim Tae Geun Kim School of Electrical Engineering Korea UniversityAnam‑ro 145Seongbuk‑guSeoulRepublic of Korea computational Electronics and nanoscience Research Laboratory School of Nanoscience and BiotechnologyShivaji UniversityKolhapur 416004India

Mechanically durable transparent electrodes are essential for achieving long-term stability in flexible optoelectronic ***,they are crucial for applications in the fields of energy,display,healthcare,and soft *** meshes represent a promising alternative to traditional,brittle,metal oxide conductors due to their high electrical conductivity,optical transparency,and enhanced mechanical *** this paper,we present a simple method for fabricating an ultra-transparent conducting metal oxide mesh electrode using selfcracking-assisted *** this method,we produced an electrode with ultra-transparency(97.39%),high conductance(Rs=21.24Ωsq^(−1)),elevated work function(5.16 eV),and good mechanical *** also evaluated the effectiveness of the fabricated electrodes by integrating them into organic photovoltaics,organic light-emitting diodes,and flexible transparent memristor devices for neuromorphic computing,resulting in exceptional device *** addition,the unique porous structure of the vanadium-doped indium zinc oxide mesh electrodes provided excellent flexibility,rendering them a promising option for application in flexible optoelectronics.

关键词： Self-cracking template Vanadium-doped indium zinc oxide mesh Organic solar cells Organic light-emitting diodes Flexible transparent memory

A computational study of the role of particle size standard deviation on the collision frequency in differential settling

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International Journal of Sediment Research 2013年第1期28卷 34-45页

作者： c.HEILIGER n.b.KAYE F.Y.TESTIK civil Engineering Clemson UniversityClemsonSC29634USA

The results of a simple computational model for differential settling are presented illustrating the significant role that particle size distribution plays in collision frequency and sedimentation rate of particles in a quiescent environment. The model tracks a large number of particles（order 10;） with log-normally distributed diameters,as they settle at their Stokes settling *** collisions are detected and result in larger particles that fall more rapidly.A number of simplifying assumptions are made in the model in order to avoid empirical correlations for phenomena such as collision efficiency and particle *** simplifying assumptions were needed to isolate and quantify the role of the particle size *** concentration profiles indicate that,even in the absence of collisions, the standard deviation（σ;） of the particle size strongly influences the bulk mass settling rate as,for largerσ;, more mass is concentrated in larger,faster falling *** collision frequency is also a strong function ofσ;. For a given mass concentration the collision frequency first increases linearly with increasingσ;as greater variation in particle size leads to greater variation in particle velocity,and shorter times for particles to catch each *** largerσ;more mass is concentrated in larger particles,so,for a given mass concentration,there are fewer particles per unit volume,increasing the mean distance between the particles and reducing the collision *** implications of these results for sedimentation measurement using optical attenuation techniques are discussed.

关键词： Settling Sediment size distribution Sediment collision frequency coefficient of variation