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Application of indocyanine green in surgery: A review of current evidence and implementation in trauma patients

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World Journal of Gastrointestinal Surgery 2023年第5期15卷 757-775页

作者： husham abdelrahman Ayman El-Menyar Ruben Peralta Hassan Al-Thani Trauma Surgery Hamad Medical CorporationDoha 3050Qatar Trauma and Vascular Surgery Hamad Medical CorporationDoha 3050Qatar

Background:Modern surgical medicine strives to manage trauma while improving outcomes using functional *** of viable tissues is crucial for the surgical management of polytrauma and burn patients presenting with soft tissue and hollow viscus *** anastomosis after traumarelated resection is associated with a high rate of *** ability of the surgeon’s bare eye to determine bowel viability remains limited,and the need for a more standardized objective assessment has not yet been ***,there is a need for more precise diagnostic tools to enhance surgical evaluation and visualization to aid early diagnosis and timely management to minimize traumaassociated *** green(ICG)coupled with fluorescence angiography is a potential solution for this *** is a fluorescent dye that responds to near-infrared ***:We conducted a narrative review to address the utility of ICG in the surgical management of patients with trauma as well as elective ***:ICG has many applications in different medical fields and has recently become an important clinical indicator for surgical ***,there is a paucity of information regarding the use of this technology to treat ***,angiography with ICG has been introduced in clinical practice to visualize and quantify organ perfusion under several conditions,leading to fewer cases of anastomotic *** has great potential to bridge this gap and enhance the clinical outcomes of surgery and patient ***,there is no consensus on the ideal dose,time,and manner of administration nor the indications that ICG provides a genuine advantage through greater safety in trauma surgical ***:There is a scarcity of publications describing the use of ICG in trauma patients as a potentially useful strategy to facilitate intraoperative decisions and to limit the extent of surgical *** review will impro

关键词： Trauma Indocyanine green Fluorescence angiography Perfusion imaging Fluorescence guided surgery Acute care surgery

Experimental Studies on Critical Heat Flux in a Uniformly Heated Vertical Tube at Low Pressure and Flowrates

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Journal of Energy and Power Engineering 2012年第1期6卷 60-69页

作者： husham M. Ahmed Department of Mechanical Engineering Gulf University P.O.Box： 26489 Manama Bahrain

Investigations into critical beat flux at low flow and pressure conditions are of particular interest when predicting the nuclear reactor core behavior during Loss of Coolant accident （LOCA）. Therefore, critical heat flux （CHF） has been investigated in a uniformly heated vertical round tube at two low system pressures and six low water flowrates. The results have been compared with two correlations which have different approaches and CHF look-up table. Good agreements have been obtained for the three comparisons at the lower sets of mass fluxes. The Bowring correlation was found to be the best to correlate the experimental results with Root Mean Square Error RMSE of 0.54% and 0.56% for the 5 bar and 15 bar system pressure respectively. A comparisons with the Shim and Lee correlation yielded RMSE of 0.23% and 5.74% for the two system pressure respectively. When the look-up table of Groeneveld et al. was used, RMES of 0.55% and 25.2% was obtained for the two system pressure respectively.

关键词： Critical heat flux dryout burnout subcooled boiling LOCA.

The Comparison between Solar Water Distillation with and without a Cooling Tube

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Journal of Energy and Power Engineering 2012年第2期6卷 195-200页

作者： husham M. Ahmed Arkan Kh. AI Taie Mubarak Almea Department of Mechanical Engineering Gulf University P.O.Box. 26489 Manama Bahrain

A solar still system is designed and built to utilize solar energy in the Gulf States region to produce fresh water from brackish and sea water. This experimental work has been conducted with and without a cooling tube. The results showed that the daily production rate of the simple solar still without a cooling tube is slightly higher than that with a cooling tube. This could be due to the fact that the cooling tube has a smaller effective condensation surface area than the glass cover of the simple still. The cooling tube also reduces the solar energy that reaches the water in the still. It might also be due to the fact that the use of a cooling tube has the effect of reducing the average temperature in the solar still cavity. This resulted in reducing the evaporation rate and consequently reduced the production rate.

关键词： Solar energy solar still distillation desalination.

Multiple Organ Dysfunction Syndrome (MODS): Is It Preventable or Inevitable?

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International Journal of Clinical Medicine 2012年第7期3卷 722-730页

作者： Ayman El-Menyar Hassan Al Thani El Rasheid Zakaria Ahmad Zarour Mazin Tuma husham Abdulrahman Ashok Parchani Ruben Peralta Rifat Latifi Clinical Medicine Weill Cornell Medical School Doha Qatar Medical Research Center Hamad Medical Corporation (HMC) Doha Qatar The Clinical Research Trauma Surgery Hamad Medical Corporation (HMC) Doha Qatar Trauma surgery Hamad Medical Corporation (HMC) Doha Qatar

Multiple organ dysfunction syndrome (MODS) is a systemic, dysfunctional inflammatory response that requires long intensive care unit (ICU) stay. It is characterized with high mortality rate depending on the number of organs involved. It has been recognized that organ failure does not occur as an all-or-none rule, but rather a range of organ dysfunction exists resulting in clinical organ failure. In the absence of a gold standard scoring or tool for early diagnosis or prediction of MODS, a novel bio-clinical scoring is mandatory. Moreover, understanding the pathophysiology of MODS in medical, surgical and trauma, ICUs should take a priority to achieve a favorable outcome. Herein we reviewed the literatures published in English language through the research engines (MEDLINE, Scopus, and EBASE) from 1982 to 2011 using key words: “multiorgan dysfunction”, “organ failure”, “intensive care units” to highlight the definition, mechanism, diagnosis and prediction of MODS particularly at its earliest stages. Bring up new bio-clinical scoring to a stage where it is ready for field trials will pave the way for implementing new risk-stratification strategy in the intensive care to reduce the morbidity and mortality and save resources. Prospective studies are needed to answer our question and to shift MODS from an inevitable to a preventable disorder.

关键词： Multiorgan Dysfunction Failure Intensive Care Units

Efficient calculation of fluid-induced wall shear stress within tissue engineering scaffolds by an empirical model

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Medicine in Novel Technology and Devices 2023年第2期18卷 267-271页

作者： husham Ahmed Matthew Bedding-Tyrrell Davide Deganello Zhidao Xia Yi Xiong Feihu Zhao Zienkiewicz Centre for Computational Engineering and Department of Biomedical Engineering Faculty of Science&EngineeringSwansea UniversitySwanseaSA18ENUK Welsh Centre for Printing and Coating Faculty of Science and EngineeringSwansea UniversitySwanseaSA18ENUK Centre for Nanohealth Swansea University Medical School and Faculty of MedicineHealth and Life ScienceSwansea UniversitySwanseaSA35AUUK School of System Design and Intelligent Manufacturing Southern University of Science and TechnologyShenzhen518055China

Mechanical stimulation,such as fluid-induced wall shear stress(WSS),is known that can influence the cellular ***,in some tissue engineering experiments in vitro,mechanical stimulation is applied via bioreactors to the cells in cell culturing to study cell physiology and *** 3D cell culturing,porous scaffolds are used for housing the *** is known that the scaffold porous geometries can influence the scaffold permeability and internal WSS in a bioreactor(such as perfusion bioreactor).To calculate the WSS generated on cells within scaffolds,usually computational fluid dynamics(CFD)simulation is ***,the limitations of the computational method for WSS calculation are:(i)the high time cost of the CFD simulation(in particular for the highly irregular geometries);(ii)accessibility to the CFD model for some cell culturing experimentalists due to the knowledge *** address these limitations,this study aims to develop an empirical model for calculating the WSS based on scaffold *** model can allow the tissue engineers to efficiently calculate the WSS generated within the scaffold and/or determine the bioreactor loading without performing the computational simulations.

关键词： Wall shear stress Permeability Empirical model Tissue engineering scaffold Bioreactor