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科技军民融合发展的网络结构及路径研究——基于《“十三五”科技军民融合发展专项规划》的分析

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科技管理研究 2019年第18期39卷 32-40页

作者：胡慧姿章磊辛安张晔空军工程大学研究生院空军工程大学装备管理与无人机工程学院空军勤务学院航材四站系空军勤务学院教保处

科技军民融合是军地双方多领域合作的复杂性系统工程,以《"十三五"科技军民融合发展专项规划》文件作为分析对象,通过收集相关文献和政策文件,运用文本分析方法和社会网络法来刻画出我国科技军民融合发展网络结构,并运用可视化和定量的... 详细信息

科技军民融合是军地双方多领域合作的复杂性系统工程,以《"十三五"科技军民融合发展专项规划》文件作为分析对象,通过收集相关文献和政策文件,运用文本分析方法和社会网络法来刻画出我国科技军民融合发展网络结构,并运用可视化和定量的方法来从行为主体和重点任务两个方面分析其发展的基本路径,即以"政府、军方为核心,科研机构、高等院校为主体,中介组织为桥梁"的多元主体共治发展模式,以及"统筹建设,系统推进,重点实施"的重点任务建设路径,从而为持续深化我国科技军民融合发展提供理论支撑。

关键词：科技军民融合社会网络分析网络结构中心度结构洞

空军特种飞机保障设备军民一体化发展途径综述

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航空工程进展 2018年第A1期9卷 6-11页

作者：胡慧姿张诤敏辛安空军工程大学研究生学院西安710053 空军工程大学装备管理与无人机工程学院西安710053

军民融合战略深入发展的同时，也给空军特种飞机保障创造了新的机遇。以空军特种飞机保障设备为分析对象，在阐述美空军航空保障设备军民一体化发展特点的基础上，指出当前我军航空保障设备发展存在的不足，以军民融合式发展道路为指向... 详细信息

军民融合战略深入发展的同时，也给空军特种飞机保障创造了新的机遇。以空军特种飞机保障设备为分析对象，在阐述美空军航空保障设备军民一体化发展特点的基础上，指出当前我军航空保障设备发展存在的不足，以军民融合式发展道路为指向，从国情军情、供应商管理、信息化建设和保障模式四个方面提出新时期空军特种飞机保障设备军民一体化发展途径，可为空军特种飞机保障设备一体化发展提供了理论依据。

关键词：军民融合战略保障设备特种飞机军民一体化发展途径

Crocus sativus *** anti-inflammatory effects and regulates the NLRP3–NF-κB pathway

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Acupuncture and Herbal Medicine 2024年第3期4卷 375-385页

作者： Liang Yang huanhua Xu Qian Hong Nuo Xu Yan Zhang Rui Tao Shuai Li Zizheng Zhang Jiahao Geng Zihan Wang huizi hu Yan Dong Zhaoyi Chu Bin Zheng Jinmiao Zhu Ming Geng Yue Gao School of Chemistry and Pharmaceutical Engineering Hefei Normal UniversityHefeiChina National Key Laboratory for the Modernization of Classical and Famous Prescriptions of Chinese Medicine Jiangxi University of Chinese MedicineNanchangChina huaihai Hospital Affiliated to Xuzhou Medical University/PLA 71st Group Military Hospital XuzhouChina Beijing Institution of Radiation Medicine BeijingChina

Objective:This study aimed to evaluate the anti-inflammatory effects of petal and stamen extracts of saffron crocus(Crocus sativus)and explore the underlying ***:Local and systemic inflammation models were used to investigate the anti-inflammatory effects of ***.A xyleneinduced inflammation model or lipopolysaccharide(LPS)-induced inflammation model was used in this *** petal and stamen extracts were each administered to the mice in the xylene and LPS models by gavage for 14 d at 0.1 and 0.4 g/kg doses,***-linked immunosorbent assay(ELISA)was used to measure the concentrations of tumor necrosis factor(TNF)-αand interleukin(IL)-1βin mouse *** and eosin(H&E)staining was used to observe the pathological changes in the ear in the xylene-induced inflammation model and in the spleen in the LPS-induced inflammation ***-like receptor thermal protein domain associated protein 3(NLRP3)protein levels within the nuclear factor-kappa B(NF-κB)pathway were assessed using western ***264.7 cells were treated with LPS(5μg/mL)and LPS+***(0.05,0.1,and 0.2 mg/mL)for 24 h,and a Cell Counting Kit-8 was used to measure cell *** in NLRP3 and NF-κB levels were evaluated by western ***:Petal and stamen extracts of *** attenuated the anti-inflammatory effects in local or systemic inflammatory models and repaired pathological changes in the ear in the xylene-induced inflammation model and spleen in the LPS-induced inflammation *** extracts also decreased the concentrations of TNF-αand IL-1βin the mouse serum in the LPS-induced inflammation *** downregulated NLRP3 protein level through the NF-κB pathway and downregulated LC-3 and BECLIN1 in vivo and in *** Cyanide3-ChloroPhenylhydrazone(CCCP)weakened the effects of *** on the NLRP3–NF-κB ***:*** has anti-inflammatory effects and regulates the NLRP3-NF-κB pathway.

关键词： Autophagy Crocus sativus L. Inflammatory NOD-like receptor thermal protein domain associated protein 3 Nuclear factor kappa B

Photo‑Energized MoS_(2)/CNT Cathode for High‑Performance Li–CO_(2)Batteries in a Wide‑Temperature Range

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Nano-Micro Letters 2025年第1期17卷 160-175页

作者： Tingsong hu Wenyi Lian Kang hu Qiuju Li Xueliang Cui Tengyu Yao Laifa Shen Jiangsu Key Laboratory of Materials and Technologies for Energy Storage College of Materials Science and TechnologyNanjing University of Aeronautics and AstronauticsNanjing 210016People’s Republic of China

Li–CO_(2) batteries are considered promising energy storage systems in extreme environments such as Mars;however,severe performance degradation will occur at a subzero temperature owning to the sluggish reaction ***,a photo-energized strategy adopting sustainable solar energy in wide working temperature range Li–CO_(2) battery was achieved with a binder-free MoS_(2)/carbon nanotube(CNT)photo-electrode as *** unique layered structure and excellent photoelectric properties of MoS_(2) facilitate the abundant generation and rapid transfer of photo-excited carriers,which accelerate the CO_(2) reduction and Li_(2)CO_(3) decomposition upon *** illuminated battery at room temperature exhibited high discharge voltage of 2.95 V and mitigated charge voltage of 3.27 V,attaining superior energy efficiency of 90.2%and excellent cycling stability of over 120 *** at an extremely low temperature of−30℃,the battery with same electrolyte can still deliver a small polarization of 0.45 V by the photoelectric and photothermal synergistic mechanism of MoS_(2)/CNT *** work demonstrates the promising potential of the photo-energized wide working temperature range Li–CO_(2) battery in addressing the obstacle of charge overpotential and energy efficiency.

关键词： Li-CO_(2)batteries Photo-energized Wide operation-temperature Kinetics MoS_(2)

Fabrication and Mechano-sensing Characteristics of Bending Polypyrrole Actuator

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 240-245页

作者： CHEN Jinyou hu Wei School of Automotive Engineering Hunan Financial&Industrial Vocational-technical CollegeHengyang 421002China College of Mechanical and Electrical Engineering Hunan Agricultural UniversityChangsha 410128China

To prepare a conductive polymer actuator with decent performance,a self-built experimental platform for the preparation of polypyrrole film is *** of the essential goals is to examine the mechanical characteristics of the actuator in the presence of various combinations of process parameters,combined with the orthogonal test method of"four factors and three levels".The bending and sensing characteristics of actuators of various sizes are methodically examined using a self-made bending polypyrrole *** functional relationship between the bending displacement and the output voltage signal is established by studying the characteristics of the actuator sensor subjected to various degrees of *** experimental results reveal that the bending displacement of the actuator tip almost exhibits a linear variation as a function of length and *** the voltage reaches 0.8 V,the bending speed of the actuator tends to be ***,the mechanical properties of the self-assembled polypyrrole actuator are verified by the design and fabrication of the microgripper.

关键词： conductive polymer polypyrrole mechanical characteristics actuators sensing characteristics

Effect of Nb-V microalloying on the hot deformation behavior of medium Mn steels

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 360-368页

作者： Yumeng Wang Qinyi Guo Bin hu Haiwen Luo School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China

The influence of Nb-V microalloying on the hot deformation behavior and microstructures of medium Mn steel(MMS)was investigated by uniaxial hot compression *** establishing the constitutive equations for simulating the measured flow curves,we successfully constructed deformation activation energy(Q)maps and processing maps for identifying the region of flow *** concluded the following consequences of Nb-V alloying for MMS.(i)The critical strain increases and the increment diminishes with the increasing deformation temperature,suggesting that NbC precipitates more efficiently retard dynamic recrystallization(DRX)in MMS compared with solute Nb.(ii)The deformation activation energy of MMS is significantly increased and even higher than that of some reported high Mn steels,suggesting that its ability to retard DRX is greater than that of the high Mn content.(iii)The hot workability of MMS is improved by narrowing the hot processing window for the unstable flow stress,in which fine recrystallized and coarse unrecrystallized grains are present.

关键词： medium manganese steel niobium-vanadium microalloying flow behavior dynamic recrystallization hot workability

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军民融合背景下军民两用技术研发政策研究

中国科技论坛 2018年第5期 121-127页

作者：章磊胡慧姿李肇欣空军工程大学装备管理与安全工程学院西安交通大学绩效管理研究中心陕西省交通职业技术学院

本文从军民融合政策的演化历程入手,系统梳理了与军民两用技术研发相关的政策法规,识别了其关键内容。并以现有相关政策文本为研究样本,从政策工具和研发活动两个维度构建了军民两用技术研发政策分析的二维框架,运用该框架进行具体分析... 详细信息

本文从军民融合政策的演化历程入手,系统梳理了与军民两用技术研发相关的政策法规,识别了其关键内容。并以现有相关政策文本为研究样本,从政策工具和研发活动两个维度构建了军民两用技术研发政策分析的二维框架,运用该框架进行具体分析,揭示了当前军民两用技术研发政策的现状,总结现有政策在基础研究活动支持、供给型政策制定等方面存在的不足,提出了相应的措施建议,以期为后续改善和制定相关政策法规提供参考。

关键词：军民融合军民两用技术研发政策

Tumor inflammation-specific self-amplifying fluorescent molecular probes induce an anti-tumor immune response

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Science China Chemistry 2025年第1期68卷 273-287页

作者： Shuguang Yang Lijun hu Hong Xiao Zecong Xiao Xintao Shuai PCFM Lab of Ministry of Education School of Materials Science and Engineering Sun Yat-sen University Department of Ultrasound The Fifth Affiliated Hospital Sun Yat-sen University Department of Medical Ultrasound The Third Affiliated Hospital of Sun Yat-sen University Nanomedicine Research Center The Third Affiliated Hospital of Sun Yat-sen University

Enhancing the concentration of exogenous molecular drugs within the tumor microenvironment through enzyme-catalyzed polymerization presents a novel strategy for cancer therapy. Nonetheless, the optimization of the catalytic efficiency is often impeded by the inefficient expression of enzymes. Herein, we reported a self-amplifying fluorescent molecular probe, Bis-HTPICG, for photodynamic therapy(PDT) and subsequent PDT-induced immunoreaction. The Bis-HTP-ICG probe possesses a noticeable enzyme-catalyzed polymerization facilitated by myeloperoxidase(MPO), a crucial enzyme secreted by neutrophils at inflammation sites. Upon exposure to laser irradiation, Bis-HTP-ICG showed a high PDT efficacy, inducing an acute inflammatory response that stimulates further recruitment of neutrophils and then elevated MPO secretion. The heightened level of MPO enhances the accumulation of the Bis-HTP-ICG via self-polymerization or binding with intratumoral proteins following MPO enzyme catalysis, instigating a self-amplifying chain reaction cycle involving Bis-HTP-ICG, neutrophils and ***, PDT efficiently incites immunogenic cell death(ICD) in tumor cells, initiating an anti-tumor immune response including dendritic cells(DCs) maturation, T cell proliferation and reprogramming of tumor-associated neutrophils(TANs). This work portrays a promising strategy for self-amplification of fluorescent molecular probes through adjustable enzyme levels,potentially offering a unique avenue to enhance the tumor accumulation of molecular drugs for improved tumor therapy.

关键词： fluorescent molecular probes self-amplifying myeloperoxidase photodynamic therapy

Optimizing Fine-Tuning in Quantized Language Models:An In-Depth Analysis of Key Variables

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Computers, Materials & Continua 2025年第1期82卷 307-325页

作者： Ao Shen Zhiquan Lai Dongsheng Li Xiaoyu hu National Key Laboratory of Parallel and Distributed Computing National University of Defense TechnologyChangsha410073China Strategic Assessments and Consultation Institute Academy of Military ScienceBeijing100091China

Large-scale Language Models(LLMs)have achieved significant breakthroughs in Natural Language Processing(NLP),driven by the pre-training and fine-tuning *** this approach allows models to specialize in specific tasks with reduced training costs,the substantial memory requirements during fine-tuning present a barrier to broader ***-Efficient Fine-Tuning(PEFT)techniques,such as Low-Rank Adaptation(LoRA),and parameter quantization methods have emerged as solutions to address these challenges by optimizing memory usage and computational *** these,QLoRA,which combines PEFT and quantization,has demonstrated notable success in reducing memory footprints during fine-tuning,prompting the development of various QLoRA *** these advancements,the quantitative impact of key variables on the fine-tuning performance of quantized LLMs remains *** study presents a comprehensive analysis of these key variables,focusing on their influence across different layer types and depths within LLM *** investigation uncovers several critical findings:(1)Larger layers,such as MLP layers,can maintain performance despite reductions in adapter rank,while smaller layers,like self-attention layers,aremore sensitive to such changes;(2)The effectiveness of balancing factors depends more on specific values rather than layer type or depth;(3)In quantization-aware fine-tuning,larger layers can effectively utilize smaller adapters,whereas smaller layers struggle to do *** insights suggest that layer type is a more significant determinant of fine-tuning success than layer depth when optimizing quantized ***,for the same discount of trainable parameters,reducing the trainable parameters in a larger layer is more effective in preserving fine-tuning accuracy than in a smaller *** study provides valuable guidance for more efficient fine-tuning strategies and opens avenues for further research into optimizing LLM

关键词： Large-scale Language Model Parameter-Efficient Fine-Tuning parameter quantization key variable trainable parameters experimental analysis