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水力采煤与管道运输 2019年第2期 62-65页

作者：白惠元姜玉婷山西大同大学煤炭工程学院

对阻化剂阻燃机理和影响因素进行了详细分析,探讨了目前常用阻化剂的分类、作用机理和优缺点,提出了合理选择阻化剂的重要性,并对阻化剂未来发展的方向和趋势进行了阐述,为有效防治矿井火灾提供了依据。

关键词：煤矿阻化剂自燃

PDCA循环护理对房颤射频消融术患者NRS评分及疼痛管理满意度的影响

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临床医学工程 2020年第11期27卷 1537-1538页

作者：李瑶瑶摆惠媛河南省人民医院/郑州大学人民医院河南郑州450003

目的探讨PDCA循环护理对房颤射频消融术患者NRS评分及疼痛管理满意度的影响。方法选取2019年2月至2019年5月在我院行房颤射频消融术的62例患者,随机分为观察组与对照组,各31例。对照组采用常规护理,观察组在此基础上采用PDCA循环护理。... 详细信息

目的探讨PDCA循环护理对房颤射频消融术患者NRS评分及疼痛管理满意度的影响。方法选取2019年2月至2019年5月在我院行房颤射频消融术的62例患者,随机分为观察组与对照组,各31例。对照组采用常规护理,观察组在此基础上采用PDCA循环护理。比较两组患者各时间点的NRS评分以及疼痛管理满意度。结果护理后,观察组T1、 T2、 T3、 T4时的NRS评分均低于对照组(P <0.05)。观察组的疼痛管理满意度为96.77%,明显高于对照组的74.19%(P <0.05)。结论 PDCA循环护理在房颤射频消融术患者中的应用效果较好,可有效缓解患者的疼痛,提高其疼痛管理满意度。

关键词：房颤射频消融术 NRS评分疼痛管理满意度

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强化建设市场稽查规范建设市场行为

河北建筑工程学院学报 2001年第1期19卷 92-93页

作者：黄嵘王雪红白会元张家口市建筑市场稽查站张家口市工程承包公司

针对目前建设市场稽查工作中暴露出的问题,进行分析、研究、并提出解决办法。

关键词：稽查建设市场管理体制市场管理

Tanshinone IIA Suppresses Non-Small Cell Lung Cancer Through Beclin-1-Mediated Autophagic Apoptosis

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Engineering 2022年第12期19卷 128-138页

作者： Shasha bai Sainan Cui Wenhao Wen Elaine Lai-Han Leung Jing bai huiyuan Lin Yongfei Cui Lei Yang Zhongqiu Liu Yuan Zheng Rong Zhang School of Pharmaceutical Sciences Guangzhou University of Chinese MedicineGuangzhou 510006China State Key Laboratory of Quality Research in Chinese Medicine/Macao Institute for Applied Research in Medicine and Health Macao University of Science and TechnologyMacao 999078China Cardiothoracic Surgery Department The Second Clinical College of Guangzhou University of Chinese MedicineGuangdong Provincial Hospital of Chinese MedicineGuangzhou 510006China

It is necessary to develop a new strategy for treatment of lung cancer since it is the main cause of cancer *** IIA(Tan IIA),an active ingredient of a commonly used traditional Chinese herb Salvia miltiorrhiza,provides a new direction to develop a new strategy for the *** has been found that Tan IIA could inhibit lung cancer in vitro and in vivo by inducing autophagic *** IIA increased apoptotic cells and the expression of cleaved caspase 3 and cleaved caspase 9,decreased B-cell lymphoma-2(Bcl-2)/Bcl-2 associated X protein(Bax)ratio in human non-small cell lung cancer(NSCLC)cell lines,which was promoted by an autophagy activator Rapamycin,and weaken by autophagy inhibitor 3-methyladenine(3-MA).In addition,Tan IIA induced more autophagosomes,up-regulated light chain 3b(LC-3B)I and LC-3B II conversion and less sequestosome 1(SQSTM1/p62)expression,which cannot be weakened by the caspase 3 ***,overexpression of LC-3B gene(LC3B)and downregulation of autophagic gene 5(ATG5)further confirmed that Tan IIA induced autophagic apoptosis in NSCLC cell ***-1 gene(BECN1)overexpression and silence attenuated the effects of Tan IIA,suggesting autophagic apoptosis that Tan IIA induced was dependent on ***,our study demonstrated a new treatment mechanism of Tan IIA and suggested that Tan IIA is a potential new anti-cancer therapeutic option.

关键词： Tan IIA Autophagy Apoptosis Beclin-1

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认证审核客户价值量提升探讨

安全、健康和环境 2013年第8期13卷 20-22页

作者：杨国栋丁晓刚赵勇白慧渊杨艳丽中国石化安全工程研究院山东青岛266071 中国石化中原油田天然气处理厂河南濮阳457000

通过分析认证客户价值量需求,以增值审核为切入点,从量身定制增值审核方案和开发个性化增值审核产品2个角度对价值量的增值进行了探讨。

关键词：客户价值增值审核审核方案审核产品

In-situ structure reconstitution of NiCo2Px for enhanced electrochemical water oxidation

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科学通报：英文版 2017年第22期62卷 1510-1518页

作者： Xue bai Zhiyu Ren Shichao Du huiyuan Meng Jun Wu Yuzhu Xue Xiaojun Zhao Honggang Fu Tianjin Key Laboratory of Structure and Performance for Functional Molecules Key Laboratory of Inorganic-Organic Hybrid Functional Material Chemistry Ministry of Education of the People's Republic of China Tianjin Normal University Tianjin 300387 China Key Laboratory of Functional Inorganic Material Chemistry Ministry of Education of the People's Republic of China School of Chemistry and Materials Science Heilongjiang University Harbin 150080 China

Gaining insight into the structure evolution of transition-metal phosphides during anodic oxidation is significant to understand their oxygen evolution reaction(OER) mechanism, and then design highefficiency transition metal-based catalysts. Herein, NiCo_2P_x nanowires(NWs) vertically grown on Ni foam were adopted as the target to explore the in-situ morphology and chemical component reconstitution during the anodic oxidation. The major factors causing the transformation from NiCo_2P_x into the hierarchical NiCo_2P_x@CoNi(OOH)_x NWs are two competing reactions: the dissolution of NiCo_2P_x NWs and the oxidative re-deposition of dissolved Co^(2+) and Ni^(2+) ions, which is based primarily on the anodic bias applied on NiCo2 Px NWs. The well balance of above competing reactions, and local pH on the surface of NiCo_2P_x NW modulated by the anodic oxidation can serve to control the anodic electrodeposition and rearrangement of metal ions on the surface of NiCo_2P_x NWs, and the immediate conversion into CoNi(OOH)_x. Consequently, the regular hexagonal CoNi(OOH)_x nanosheets grew around NiCo_2P_x *** from the active catalytic sites on the surface and the sufficient conductivity, the resultant NiCo_2P_x@CoNi(OOH)_x arrays also display good OER activity, in terms of the fast kinetics process, the high energy conversion efficiency, especially the excellent durability. The strategy of in-situ structure reconstitution by electrochemical reaction described here offers a reliable and valid way to construct the highly active systems for various electrocatalytic applications.

关键词： NiCo2Px Structure reconstitution Anodic oxidation CoNi(OOH)x Oxygen evolution reaction(OER)

Aging Behavior of Nano-SiC/2014Al Composite Fabricated by Powder Metallurgy and Hot Extrusion Techniques

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Journal of Materials Science & Technology 2016年第10期32卷 1008-1012页

作者： Zhiguo Wang Chuanpeng Li huiyuan Wang Xian Zhu Min Wu Jiehua Li Qichuan Jiang Key Laboratory of Automobile Materials of Ministry of Education&School of Materials Science and Engineering Nanling CampusJilin UniversityChangchun 130025China Center of Analytical and Testing Beihua UniversityJilin 132013China Chair of Casting Research Montanuniversitaet LeobenLeoben 8700Austria

The aging-hardening kinetics of powder metallurgy processed 2014Al alloy and its composite have been studied. The existence of n-SiC particulates leads to the increase of peak hardness. Interestingly, the aginghardening peak of the composite takes place at earlier time than that of the unreinforced alloy. Transmission electron microscopy（TEM） studies indicated that the major precipitation phases are Al_5Cu_2Mn_3 and θ′（Al_2Cu）. Besides, Ω phase appeared in both specimens at peak hardening condition, which has been rarely observed previously in aluminum metal matrix composites without Ag. Accelerated aging kinetics and increased peak hardness may be attributed to the higher dislocation density resulted from the mismatch of coefficients of thermal expansion between n-SiC and 2014Al matrix. The results are beneficial to fabricating high performance composites for the application in automobile field such as pistons, driveshaft tubes, brake rotors, bicycle frames, railroad brakes.

关键词： Metal matrix composites Nano-SiC Powder metallurgy Hot extrusion Aging hardening

规范化介入护理在经股动脉入路行经导管主动脉瓣膜置换术患者中的应用效果

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中国社区医师 2023年第24期39卷 116-118页

作者：王慧源白彦越曹慧哈尔滨医科大学附属第二医院心内科导管室黑龙江哈尔滨150001

目的:探讨规范化介入护理在经股动脉入路行经导管主动脉瓣膜置换术(TAVR)患者中的应用效果。方法:选取2019年11月—2022年4月于哈尔滨医科大学附属第二医院接受经股动脉入路行TAVR的主动脉瓣病变患者60例作为研究对象,以随机数字表法分... 详细信息

目的:探讨规范化介入护理在经股动脉入路行经导管主动脉瓣膜置换术(TAVR)患者中的应用效果。方法:选取2019年11月—2022年4月于哈尔滨医科大学附属第二医院接受经股动脉入路行TAVR的主动脉瓣病变患者60例作为研究对象,以随机数字表法分为对照组与观察组,各30例。对照组实施传统围术期护理,观察组在对照组基础上实施规范化介入护理。比较两组护理效果。结果:观察组手术时间、住院时间短于对照组,差异有统计学意义(P<0.05)。护理后,观察组生活质量各维度评分均高于对照组,差异有统计学意义(P<0.001)。观察组总满意度高于对照组,差异有统计学意义(P=0.005)。两组患者术后均未发生并发症。结论:规范化介入护理应用于经股动脉入路行TAVR的患者中,能缩短其手术时间、住院时间,提高生活质量、护理满意度,安全性较高。

关键词：规范化介入护理心脏瓣膜置换术经股动脉入路

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水系锌离子电池正极材料钒酸铵盐的研究进展

成都大学学报（自然科学版） 2023年第3期42卷 274-282页

作者：杨智卢超白仟宇陈辉源李涛成都大学机械工程学院四川成都610106

水系锌离子电池以高比容量的锌金属为负极,具有低成本、高安全性与无毒环保等优良特性,成为了当前备受关注的新型储能装置之一.然而,目前难以开发出与锌负极相匹配的正极材料,这成为了制约水系锌离子电池大规模发展的重要因素.钒酸铵盐... 详细信息

水系锌离子电池以高比容量的锌金属为负极,具有低成本、高安全性与无毒环保等优良特性,成为了当前备受关注的新型储能装置之一.然而,目前难以开发出与锌负极相匹配的正极材料,这成为了制约水系锌离子电池大规模发展的重要因素.钒酸铵盐因具有较快的离子扩散速率和较高的比容量而在水系锌离子电池正极材料领域展现出广阔的应用前景.首先介绍了钒酸铵盐正极材料的锌存储机制及其水热法制备工艺,针对钒酸铵盐在应用过程中存在的钒溶解与电导率较低等问题,着重综述了金属离子插层、水分子插层、聚合物插层、材料复合与氧空位构建等优化改性策略.最后,对钒酸铵盐正极材料的发展趋势进行了展望,为高性能水系锌离子电池的设计与开发提供借鉴.

关键词：水系锌离子电池钒酸铵盐正极材料插层氧空位

Glycine origin of the methyl substituent on C7′-N of octodiose for the biosynthesis of apramycin

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Science China(Life Sciences) 2006年第4期49卷 362-369页

作者： XU Mingxuan ZHU Yinming Jin Zhikun WU huiyuan LI Xiangfeng YANG Yunliu JIAO Ruisheng JIANG Weihong WU Houming TIAN Wei bai Xiufeng ZHAO Guoping Laboratory of Molecular Microbiology Institute of Plant Physiology and EcologyShanghai Institutes for Biological ScienceChinese Academy of SciencesShanghai 200032China Department of Biopharmaceutics Shenyang Pharmaceutical UniversityShenyang 110016China State Key Laboratory of Bio-Organic&Natural Products Chemistry Shanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai 200032China

Apramycin is unique in the aminoglycoside family due to its octodiose moiety. However, either the biosynthesis process or the precursors involved are largely unknown. Addition of glycine, as well as serine or threonine, to the Streptomyces tenebrabrius UD2 fermentation medium substantially increases the production of apramycin with little effect on the growth of mycelia, indicating that glycine and/or serine might be involved in the biosynthesis of apramycin. The 13C-NMR analysis of [2-13C] glycine-fed (25% enrichment) apramycin showed that glycine specifically and efficiently incorporated into the only N-CH3 substituent of apramycin on the C7′ of the octodiose moiety. We noticed that the in vivo concentration of S-adenosyl methionine increased in parallel with the addition of glycine, while the addition of methione in the fermentation medium significantly decreased the productivity of apra-mycin. Therefore, the methyl donor function of glycine is proposed to be involved in the methionine cycle but methionine itself was proposed to inhibit the methylation and methyl transfer processes as previously reported for the case of rapamycin. The 15N NMR spectra of [2-13C,15N]serine labeled apramycin indicated that serine may also act as a limiting precursor contributing to the ―NH2 substituents of apramycin.

关键词： Streptomyces tenebrabrius apramycin,octodiose 13C-NMR [2-13C]glycine 15N-NMR [2-13C,15N]serine.