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Construction of dual Z-scheme Bi2WO6/g-C_(3)N_(4)/black phosphorus quantum dots composites for effective bisphenol A degradation

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Journal of Environmental Sciences 2023年第2期124卷 617-629页

作者： Fuyou Du Zhan Lai huiyang tang Haiyan Wang Chenxi Zhao College of Biological and Environmental Engineering Changsha UniversityChangsha 410022China

In this work,a novel dual Z-scheme Bi_(2)WO_(6)/g-C_(3)N_(4)/black phosphorus quantum dots(Bi_(2)WO_(6)/g-C_(3)N_(4)/BPQDs)composites were fabricated and utilized towards photocatalytic degradation of bisphenol A(BPA)under visible-light *** the content of g-C_(3)N_(4) and BPQDs in Bi_(2)WO_(6)/g-C_(3)N_(4)/BPQDs composites to a suitable mass ratio can enhance the visible-light harvesting capacity and increase the charge separation efficiency and the transfer rate of excited-state electrons and holes,resulting in much higher photocatalytic activity for BPA degradation(95.6%,at 20 mg/L in 120 min)than that of Bi2WO6(63.7%),g-C_(3)N_(4)(25.0%),BPQDs(8.5%),and Bi_(2)WO_(6)/g-C_(3)N_(4)(79.6%),*** trapping experiments indicated that photogenerated holes(h+)and superoxide radicals(•O_(2)−)played crucial roles in photocatalytic BPA ***,the possible degradation pathway and photocatalytic mechanism was proposed by analyzing the BPA *** also demonstrated that the Bi2WO6/g-C_(3)N_(4)/BPQDs as effective photocatalystswas stable and have promising potential to remove environmental contaminants from real water samples.

关键词： Dual Z-scheme Bi_(2)WO_(6) Graphitic carbon nitride(g-C_(3)N_(4)) Black phosphorus quantum dots (BPQDs) Bisphenol A(BPA)

Phage-displayed heptapeptide sequence conjugation significantly improves the specific targeting ability of antimicrobial peptides against Staphylococcus aureus

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mLife 2024年第2期3卷 251-268页

作者： Tao Wang Peng Tan Qi tang Chenlong Zhou Yakun Ding Shenrui Xu Mengda Song huiyang Fu Yucheng Zhang Xiaohui Zhang Yueyu Bai Zhihong Sun Xi Ma State Key Laboratory of Animal Nutrition and Feeding College of Animal Science and TechnologyChina Agricultural UniversityBeijingChina Luoyang Key Laboratory of Animal Genetic and Breeding College of Animal ScienceHenan University of Science and TechnologyLuoyangChina Key Laboratory of Innovative Utilization of Indigenous Cattle and Sheep Germplasm Resources(Co‐construction by Ministry and Province) Ministry of Agriculture and Rural AffairsZhengzhou UniversityZhengzhouChina Animal Health Supervision in Henan Province ZhengzhouChina Laboratory for Bio‐Feed and Molecular Nutrition Department of Animal Science and TechnologySouthwest UniversityChongqingChina

Broad-spectrum antibacterial drugs often lack specificity,leading to indiscriminate bactericidal activity,which can disrupt the normal microbial balance of the host flora and cause unnecessary cytotoxicity during systemic *** this study,we constructed a specifically targeted antimicrobial peptide against Staphylococcus aureus by introducing a phage-displayed peptide onto a broad-spectrum antimicrobial peptide and explored its structure–function relationship through one-factor ***2 obtained by screening based on the selectivity index and the targeting index showed specific killing ability against ***,SFK2 showed excellent biocompatibility in mice and piglet,and demonstrated significant therapeutic efficacy against *** *** conclusion,our screening of phage-derived heptapeptides effectively enhances the specific bactericidal ability of the antimicrobial peptides against ***,providing a theoretical basis for developing targeted antimicrobial peptides.

关键词： antimicrobial peptides membrane disruption mechanism microbial infection phage display technology Staphylococcus aureus

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中国老年特应性皮炎多中心临床流行病学调查

中华医学杂志 2023年第32期103卷 2495-2501页

作者：江夏赵嘉惠唐汇洋王若珺张道军汪旸李航郝飞重庆医科大学附属第三医院皮肤整形美容中心，重庆401120 北京大学第一医院皮肤性病科国家皮肤与免疫疾病临床医学研究中心皮肤病分子诊断北京市重点实验室国家药品监督管理局化妆品质量控制与评价重点实验室，北京100034

目的调查并分析我国老年特应性皮炎(AD)患者的临床特征。方法基于全国2型炎症性皮肤病临床研究与均质化诊疗项目,收集项目中172家三甲医院自2021年6月至2023年2月就诊的年龄≥65岁并诊断为AD患者的人口学信息、临床特征及疾病严重程度... 详细信息

目的调查并分析我国老年特应性皮炎(AD)患者的临床特征。方法基于全国2型炎症性皮肤病临床研究与均质化诊疗项目,收集项目中172家三甲医院自2021年6月至2023年2月就诊的年龄≥65岁并诊断为AD患者的人口学信息、临床特征及疾病严重程度评估量表信息等,共2281例。将老年AD患者分别根据性别、有无过敏史(有过敏性疾病个人史或家族史与无过敏性疾病个人史或家族史)进行分组,分组后分别对临床特征(发病部位、AD体征)及评估量表等进行组内比较。所有计量资料采用M(Q_(1),Q_(3))表示。结果2281例老年AD患者年龄为73.02(68.83,79.62)岁,其中男性1649例(72.29%),女性632例(27.71%)。起病阶段共记录2244例,老年期起病1713例(76.34%)。过敏性疾病个人史或家族史共记录2136例,有过敏性疾病个人史或家族史者1076例(50.37%),无过敏疾病史1060例(49.63%)。皮损累及主要部位为腰背臀部,AD体征主要为面颊部和(或)头皮和(或)四肢伸侧的湿疹样皮损。中度及以上严重程度AD患者占60.58%(1327例),中重度瘙痒占81.32%(1781例),焦虑及抑郁分别占比46.14%(1011例)及39.27%(860例)。男性湿疹面积及严重程度评分(EASI)评估分数高于女性[9.67(4.77,19.28)比8.45(3.98,17.11)分](P=0.040),有过敏史患者EASI、医院焦虑抑郁量表(HADS)‑焦虑及过去1周最严重瘙痒数字评分量表(WI‑NRS)评估分数均高于无过敏史患者[9.79(4.84,19.96)比8.96(4.05,18.31)分,P=0.015;7.22(3.49,10.00)比6.81(3.12,9.33)分,P=0.012;7.64(5.62,9.07)比7.38(5.35,8.91)分,P=0.036]。结论老年AD患者有其特征性的临床表现。老年AD患者多为老年期起病,男性高于女性,皮损分布以伸侧为主,且疾病负担较重。

关键词：皮炎,特应性老年临床流行病学调查临床特征

刀具负倒棱对Ti6Al4V干式切削的影响研究

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工具技术 2022年第7期56卷 33-37页

作者：赵庆军李海峡贾天明彭俊杰唐辉阳杜明聪森泰英格(成都)数控刀具股份有限公司成都市610207 燕山大学机械工程学院

绿色制造是机械加工行业未来发展趋势,干式切削也是绿色制造的发展方向。钛合金材料因具有高强度比、抗腐蚀性和热强度等优良性能被广泛用于航空制造领域。钛合金作为一种难加工材料,在干式切削过程中会出现切削温度高、切削震动大、加... 详细信息

绿色制造是机械加工行业未来发展趋势,干式切削也是绿色制造的发展方向。钛合金材料因具有高强度比、抗腐蚀性和热强度等优良性能被广泛用于航空制造领域。钛合金作为一种难加工材料,在干式切削过程中会出现切削温度高、切削震动大、加工表面质量差和刀具磨损严重等问题。负倒棱是常见的刀具刃口处理形式之一,通过改变刃口处的材料流动情况可以改善刀具的切削性能和提高刀具的使用寿命。通过Deform 2D仿真试验,探究刀具负倒棱参数对钛合金干式切削的影响,为钛合金干式切削的刀片倒棱参数选择提供参考。

关键词：干式切削钛合金负倒棱有限元仿真

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中、西蜂蜂蜡理化指标分析及蜂蜡标准化建议

中国蜂业 2007年第10期58卷 7-9页

作者：周萍胡福良胡元强邵巧云唐慧洋浙江蜂之语蜂业集团有限公司桐庐311500 浙江大学动物科学学院杭州310029 浙江省缙云县蜂业技术协会缙云321400

本文对不同来源的中、西蜂蜂蜡样品中的杂质含量、碳氢化合物含量、密度、熔点、折光率、酸值、皂化值、酯值、碘值、总黄酮等10项理化指标进行了测定,并对蜂蜡质量指标项目的确定、质量指标值的调整等方面提出了建议。

关键词：蜂蜡理化指标标准化

特应性皮炎外周血单个核细胞潜在生物标志物的筛选及初步验证

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中华医学杂志 2023年第38期103卷 3033-3040页

作者：唐汇洋江夏张道军陈邦涛钱添姚正秋杨希余傅冰宋婷婷郝飞重庆医科大学附属第三医院皮肤整形美容中心，重庆400110 重庆大学附属三峡医院皮肤性病科，重庆404000

目的探索特应性皮炎(AD)与健康对照者外周血单个核细胞(PBMC)转录组差异,筛选出AD潜在的生物标志物并进行初步验证。方法收集2021年1月至2022年5月在重庆医科大学附属第三医院皮肤整形美容中心9例AD患者及10名健康对照者的外周血,提取P... 详细信息

目的探索特应性皮炎(AD)与健康对照者外周血单个核细胞(PBMC)转录组差异,筛选出AD潜在的生物标志物并进行初步验证。方法收集2021年1月至2022年5月在重庆医科大学附属第三医院皮肤整形美容中心9例AD患者及10名健康对照者的外周血,提取PBMC后以RNA转录组测序(RNA-seq)技术进行转录组测序及相对表达量测定,通过对差异表达基因(DEGs)进行基因本体论(GO)、京都基因与基因组百科全书(KEGG)及蛋白互作网络(PPI)分析筛选出生物标志物候选基因并进行实时荧光定量PCR(qRT-PCR)进行初步验证。结果病例组患者的年龄[M(Q_(1),Q_(3))]为26.50(22.75,30.50)岁,病程[M(Q_(1),Q_(3))]为15(10,20)年。健康对照组的年龄[M(Q_(1),Q_(3))]为37.00(27.75,40.25)岁。相对于健康对照者,AD组共检测出DEGs 1044条,其中上调基因668条,下调基因376条,DEGs经差异可变剪切(AS)分析显示外显子选择性跳跃(46.74%)及外显子跳跃(31.01%)占比较大,GO富集分析显示DEGs主要与炎症反应相关,KEGG富集分析显示DEGs主要与细胞因子相互作用及信号通路相关。综合富集分析及PPI分析筛选出趋化因子C-C基序趋化因子配体4(CCL4)、C-C基序趋化因子受体3(CCR3)、C-X-C基序趋化因子受体5(CXCR5)、核因子κB抑制因子-α(NFKBIA)、C-X-C基序趋化因子配体1(CXCL1)、白细胞介素1B(IL-1B)、C-C基序趋化因子配体20(CCL20)、淋巴细胞抗原96(LY96)作为AD生物标志物的候选基因,qRT-PCR验证显示上述细胞因子及细胞因子受体mRNA相对表达量与转录组测序结果趋势一致。结论CCL4、CCR3、CXCR5、NFKBIA、CXCL1、IL-1B、CCL20、LY96可能为AD的潜在生物标志物,参与AD的发生及发展。

关键词：皮炎,特应性外周血单个核细胞生物标志物 RNA转录组测序

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柔性直流换流站异常监控数据实时预警研究

自动化仪表 2024年第3期45卷 70-73,82页

作者：王林姚发兴王健唐力桂辉阳中国南方电网有限责任公司超高压输电公司贵州兴义562499

为了提高对异常数据的预警性能、维护柔性直流换流站的运行稳定性,提出了柔性直流换流站异常监控数据实时预警方法。首先,利用经验规则消除数据碰撞问题,根据数据信息哈希函数的异常值,准确检测出其中的异常数据。然后,利用小波变换对... 详细信息

为了提高对异常数据的预警性能、维护柔性直流换流站的运行稳定性,提出了柔性直流换流站异常监控数据实时预警方法。首先,利用经验规则消除数据碰撞问题,根据数据信息哈希函数的异常值,准确检测出其中的异常数据。然后,利用小波变换对异常监控数据进行预处理,并从异常数据中提取关键变量信息。最后,根据监控过程中出现异常数据的概率,设定预警阈值,再利用预警函数构建实时预警模型。试验结果表明,应用该方法后,误报率被控制在20%以下,平均绝对误差被控制在0.12以下。相比于传统方法,该方法的预警结果更有效、准确率更高。

关键词：柔性直流换流站监控数据异常数据数据碰撞尺度参数数据检测阈值设定

Effect of electron-withdrawing groups in conjugated bridges： molecular engineering of organic sensitizers for dyesensitized solar cells

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Frontiers of Optoelectronics 2016年第1期9卷 60-70页

作者： Jie SHI Zhaofei CHAI Runli tang huiyang LI Hongwei HAN Tianyou PENG Qianqian LI Zhen LI Department of Chemistry Hubei Key Lab on Organic and Polymeric Opto-Electronic Materials Wuhan University Wuhan 430072 China Hubei Key Laboratory of Oilcrops Lipid Chemistry and Nutrition Oil Crops Research Institute Chinese Academy of Agricultural Sciences Wuhan 430062 China Michael Gratzel Center for Mesoscopic Solar Cells Wuhan National Laboratory for Optoelectronics Huazhong University of Science and Technology Wuhan 430074 China

Four organic sensitizers containing quinoxaline or benzoxadiazole as an auxiliary electron acceptor in conjugated bridge were synthesized and utilized for dyesensitized solar cells （DSSCs）. It was found that the incorporation of different electron-withdrawing moieties can affect the absorption spectra, electronic properties, the interfacial interactions and then the overall conversion efficiencies significantly. Therefore, the appropriate selection of the auxiliary acceptor was important to optimize the photovoltaic performance of solar cells. Among these sensitizers, LI-44 based solar cell showed the best photovoltaic performance： a shortcircuit photocurrent density （Jsc） of 13.90 mA/cm2, an open-circuit photovoltage （Voc） of 0.66 V, and a fill factor （FF） of 0.66, corresponding to an overall conversion efficiency of 6.10% under standard global AM 1.5 solar light conditions.

关键词： dye-sensitized solar cells (DSSCs) auxiliary electron acceptor quinoxaline benzoxadiazole

The effect of iron on the sound velocities ofδ-AlOOH up to 135 GPa

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Geoscience Frontiers 2021年第2期12卷 937-946页

作者： Xiaowan Su Chaoshuai Zhao Chaojia Lv Yukai Zhuang Nilesh Salke Liangxu Xu Hu tang huiyang Gou Xiaohui Yu Qiang Sun Jin Liu School of Earth and Space Sciences Peking UniversityBeijing100871China Center for High Pressure Science and Technology Advanced Research Beijing100094China Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing100190China

δ-(Al,Fe)OOH is considered to be one of the most important hydrous phases on Earth,remaining stable under the extreme conditions throughout the *** behavior ofδ-(Al,Fe)OOH at high pressure is essential to understanding the deep water cycle.δ-(Al_(0.956)Fe_(0.044))OOH crystals synthesized at 21 GPa and 1473 K were investigated by high-pressure Brillouin light scattering spectroscopy and synchrotron X-ray diffraction up to 135.4 GPa in diamond anvil *** incorporation of 5 mol%FeOOH increases the unit-cell volume ofδ-AlOOH by~1%and decreases the shear-wave velocity(VS)by~5%at 20–135 *** particular,the compressional(V_(P))and shear(VS)wave velocities ofδ-(Al_(0.956)Fe_(0.044))OOH are 7%–16%and 10%–24%greater than all the major minerals in the mantle transition zone including wadsleyite,ringwoodite,and *** distinctly high sound velocities ofδ-(Al_(0.956)Fe_(0.044))OOH at 20–25 GPa may contribute to the seismic anomalies observed at~560–680 km depths in the cold and stagnant slab beneath Izu-Bonin and/or ***,the VS ofδ-(Al_(0.956)Fe_(0.044))OOH is about 10%and 4%–12%lower than iron-bearing bridgmanite Mg_(0.96)Fe_(0.05)Si_(0.99O3)and ferropericlase(Mg_(0.92)Fe_(0.08))O,respectively,under the lowermost mantle conditions,which might partially contribute to the large low-shear-velocity provinces and ultralow velocity zones at the bottom of the lower mantle.

关键词： Deep water cycle Fe-bearing delta phase Seismic anomalies High pressure