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Retrospective analysis of results of treatment for nasopharyngeal carcinoma in Macao

Chinese Journal of Cancer Research 2014年第2期26卷 148-158页

作者： huiqin dou Dongyan Hu Chileong Lam Yunsheng Liu Xiuwen Wang Wendong Zhang Department of Stomatology Qilu Hospital of Shandong University Department of Clinical Oncology Qilu Hospital of Shandong University Department of Clinical Oncology Conde S.Januario General Hospital

Background： Nasopharyngeal carcinoma （NPC） is a common malignancy in Southeast Asia, however, a full consensus has not yet been reached as to the value of comprehensive treatment for NPC. This study was designed to evaluate the epidemiological characteristics of NPC and their prognostic value, as well as the long-term efficacy of NPC treatment. Patients and methods： A total of 248 patients, with different stages of NPC, were included in this study. Results： The 5-year overall survival （OS） rates for patients in stages I, II, lII and IV were 90.48%, 76.71%, 76.89% and 33.87%, respectively （P=0.000）, while the respective 5-year progression-free survival （PFS） rates were 85.15%, 72.36%, 63.88% and 26.26% （P=0.000）. The respective 5-year OS rates, according to stage, for the group that received radiotherapy combined with chemotherapy and for the group that received radiotherapy only were as follows： stages I and II, 81.67% and 79.59% （P=0.753）; stage III, 79.91% and 70.38% （P=0.143）; stage IV,, 35.22% and 0% （P=0.000）. The respective 5-year PFS rates in these groups were as follows： stages I and II, 75.83% and 74.98% （P=0.814）; stage III, 74.08% and 42.25% （P=0.027）; stage IV,, 27.31% and 0% （P=0.000）. Conclusions： Clinical staging appears to be the most important prognostic factor for NPC. As the stage number increases, both the 5-year OS and PFS significantly decrease. Adding chemotherapy to radiotherapy was not advantageous for patients with stage I or II NPC, however the addition of chemotherapy to radiotherapy significantly improved OS and PFS in patients with stage IV NPC. The addition of chemotherapy improved PFS, but not OS in patients with stage III NPC.

关键词： Nasopharyngeal carcinoma (NPC) treatment retrospective analysis Macao

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Zn_(1-x)Cr_xO纳米粉体置换固溶体反应机理的探讨

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中国陶瓷 2017年第7期53卷 27-30页

作者：李慧勤窦树梅韩银凤宝鸡文理学院化学化工学院宝鸡721013

以水热合成Zn_(0.9)Cr_(0.1)O为例,探讨其反应机理。采用分析纯的ZnCl_2和CrCl_3为原料,以3 mol/L NaOH作为矿化剂,在260℃下,进行水热合成反应Zn_(0.9)Cr_(0.1)O稀磁半导体晶体。XRD表明所制备的Zn_(0.9)Cr_(0.1)O稀磁半导体晶体发育... 详细信息

以水热合成Zn_(0.9)Cr_(0.1)O为例,探讨其反应机理。采用分析纯的ZnCl_2和CrCl_3为原料,以3 mol/L NaOH作为矿化剂,在260℃下,进行水热合成反应Zn_(0.9)Cr_(0.1)O稀磁半导体晶体。XRD表明所制备的Zn_(0.9)Cr_(0.1)O稀磁半导体晶体发育比较好,通过UV/vis测试可以观察到Cr离子的吸收峰,说明实现了掺杂。EDS分析确定了Cr^(3+)的含量。从固溶体离子半径比、结构、离子价位和电负性分析,过渡元素Cr^(3+)在基质晶体Zn O中的固溶度是有限的,增加Cr^(3+)的含量会导致杂质相的出现,不利于形成纯净的Zn_(1-x)Cr_xO。不等价置换固溶体会产生组分缺陷,形成空位或电子空穴,在材料的电性能方面有重要意义。

关键词： zn0.9Cr0.1O 离子置换组分缺陷电子空穴

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BOARD-LEVEL BUILT-IN SELF-REPAIR METHOD OF RAM

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Journal of Electronics(China) 2012年第1期29卷 128-131页

作者： dou Yanjie Zhan huiqin Chen Yakun Shang Hongliang Department of Automation Engineering Univevsity of Electronic Science and Technology of ChinaChengdu 611731China

This paper describes the method of built-in self-repairing of RAM on board, designs hardware circuit, and logic for the RAM's faults self-repairing system based on FPGA. The key technology is that it utilizes FPGA to test RAM according to some algorithm to find out failure memory units and replace the faulty units with FPGA. Then it can build a memory that has no fault concern to external controller, and realizes the logic binding between external controller and RAM. Micro Controller Unit (MCU) can operate external RAM correctly even if RAM has some fault address units. Conventional MCS-51 is used to simulate the operation of MCU operating external memory. Simulation shows FPGA can complete the faulty address units' mapping and MCU can normally read and write external RAM. This design realizes the RAM's built-in self-repairing on board.

关键词： RAM testing Built-in self-repairing Faulty address mapping Function test

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Applications of AuNRs@SiO<sub>2</sub>Matrix Nanocomposites

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World Journal of Engineering and Technology 2021年第1期9卷 60-82页

作者： huiqin Li Shaotian Yan Lihua Wu Shumei dou Department of Chemistry and Chemical Engineering Baoji University of Arts and Sciences Baoji China Hebei Construction Material Vocational and Technical College Qinhuangdao China

Gold nanorods (AuNRs/GNR) have unique, controllable and anisotropic local surface plasmon resonance (SPR) properties, which have been widely used in biochemistry, electronics and catalysis. It is of great value and significance to study the synthesis, properties, surface modification and structural regulation of AuNRs. This paper introduces AuNRs and AuNRs@SiO2. The synthesis of AuNRs@SiO2 composite nanomaterials with quantum dots, graphene, rare earth materials and magnetic materials is described. The applications of nanocomposites in optics, biomedicine and biosensors are also discussed. The future development of nanocomposites is proposed.

关键词： AuNRs@SiO2 Matrix Composite Application Review

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Bio-inspired chiral self-assemblies promoted neuronal differentiation of retinal progenitor cells through activation of metabolic pathway

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Bioactive Materials 2021年第4期6卷 990-997页

作者： Na Sun Xiaoqiu dou Zhimin Tang Dandan Zhang Ni Ni Jiajing Wang huiqin Gao Yahan Ju Xiaochan Dai Changli Zhao Ping Gu Jing Ji Chuanliang Feng Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology Department of OphthalmologyNinth People’s HospitalShanghai Jiao Tong University School of MedicineShanghai200011China State Key Lab of Metal Matrix Composites School of Materials Science and EngineeringShanghai Jiaotong UniversityDongchuan Road 800200240ShanghaiChina

Retinal degeneration is a main class of ocular *** far,retinal progenitor cell(RPC)transplantation has been the most potential therapy for it,in which promoting RPCs neuronal differentiation remains an unmet *** address this issue,innovatively designed L/D-phenylalanine based chiral nanofibers(LPG and DPG)are employed and it finds that chirality of fibers can efficiently regulate RPCs ***,western blot,and immunofluorescence analysis show that right-handed helical DPG nanofibers significantly promote RPCs neuronal differentiation,whereas left-handed LPG nanofibers decrease this *** effects are mainly ascribed to the stereoselective interaction between chiral helical nanofibers and retinol-binding protein 4(RBP4,a key protein in the retinoic acid(RA)metabolic pathway).The findings of chirality-dependent neuronal differentiation provide new strategies for treatment of neurodegenerative diseases via optimizing differentiation of transplanted stem cells on chiral nanofibers.

关键词： Chiral structures Self-assembly Nanofibers Retinal progenitor cell Neuronal differentiation

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Hydrothermal Synthesis of CQDs and Their Properties

Hydrothermal Synthesis of CQDs and Their Properties

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中国化学会第十届全国无机化学学术会议

作者： Cui Deng Shumei dou huiqin Li Liqing Meng College of Chemistry and Chemical Engineering Baoji University of Arts and Sciences

Carbon quantum dots（CQDs） have a wide range of applications in bioimaging, biosensors, and nanocarriers due to their excellent photochemical properties, good biocompatibility, low toxicity, and easy surface modification. In this paper, glucose is used as a carbon source to prepare carbon quantum dots by one-step hydrothermal method. The effects of reaction time and reaction temperature on the test were investigated. The appearance characteristics were characterized by transmission electron microscopy. The structural properties were characterized by fluorescence spectrophotometer, Fourier infrared spectrometer and UV-visible spectrophotometer. The experimental results show that CQDs are successfully synthesized by this method, and the performance of synthetic CQDs is best when the reaction temperature is 180 °C and the reaction time is 8 h.

关键词： Carbon quantum dots Hydrothermal Fluorescence Spectroscopy Ultraviolet absorption spectrum

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Cobalt-free Li-Rich xLi2MnO3·(1-x)LiNi0.5Mn0.5O2(x=0-0.7) with high performances as cathode material for lithium-ion batteries

Cobalt-free Li-Rich xLi2MnO3·(1-x)LiNi0.5Mn0.5O2(x=0-0.7) w...

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中国化学会第三届中国能源材料化学研讨会

作者： Shumei dou Ping Li huiqin Li Fenyan Wei Engineering research center of advanced ferroelectric functional materials Shaanxi Key Laboratory of PhytochemistryCollege of Chemistry and Chemical EngineerBaoji University of Arts and Sciences

In contrast to silicon/carbon composite as anode materials that have large reversible Li capacities exceeding 1000 mAh g,superior structural stability and low cost,the commercial layered LiCoO cathode material deliver...

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图书馆非文献资源共享研究

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情报资料工作 2007年第1期28卷 64-66页

作者：豆洪青韩惠琴宁波大学图书馆浙江315211

文章研究了非文献资源共享是与文献资源共享相对的图书馆资源共享形式,它具有经济性、共生性、复杂性等特点,其经济性决定在图书馆的非文献资源共享中应该引入市场机制,以更好地保障资源共享活动的顺利运行。在引进市场机制的过程中,在... 详细信息

文章研究了非文献资源共享是与文献资源共享相对的图书馆资源共享形式,它具有经济性、共生性、复杂性等特点,其经济性决定在图书馆的非文献资源共享中应该引入市场机制,以更好地保障资源共享活动的顺利运行。在引进市场机制的过程中,在遵循一般市场原则的前提下,更要遵循非盈利原则。

关键词：非文献资源共享市场机制非盈利图书馆

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刍议读者信息获取自由

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图书馆杂志 2005年第10期24卷 20-23页

作者：豆洪青韩惠琴宁波大学图书馆浙江宁波315211

读者具有获取信息的自由,而这自由又是相对的。读者信息获取自由受法律的限制,也要法律来保护,图书馆有通过技术力量、服务意识等方面的提高来保障读者信息获取自由的责任,而读者也有维护信息自由获取环境的责任。

关键词：信息获取自由权利图书馆信息自由信息获取读者获取信息技术力量服务意识法律

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BOARD-LEVEL BUILT-IN SELF-REPAIR METHOD OF RAM

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Journal of Electronics(China) 2012年第Z1期 128-131页

作者： dou Yanjie Zhan huiqin Chen Yakun Shang Hongliang (Department of Automation Engineering, Univevsity of Electronic Science and Technology of China, Chengdu 611731, China)

This paper describes the method of built-in self-repairing of RAM on board, designs hardware circuit, and logic for the RAM’s faults self-repairing system based on FPGA. The key technology is that it utilizes FPGA to test RAM according to some algorithm to find out failure memory units and replace the faulty units with FPGA. Then it can build a memory that has no fault concern to external controller, and realizes the logic binding between external controller and RAM. Micro Controller Unit (MCU) can operate external RAM correctly even if RAM has some fault address units. Conventional MCS-51 is used to simulate the operation of MCU operating external memory. Simulation shows FPGA can complete the faulty address units’ mapping and MCU can normally read and write external RAM. This design realizes the RAM’s built-in self-repairing on board.

关键词： RAM testing Built-in self-repairing Faulty address mapping Function test

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