检索结果-南通市图书馆

Food Science and Human Wellness 2024年第2期13卷 1018-1028页

作者： huinan wang Jiaxin Zhang Xinran Liu Jinxiang wang Xuepeng Li Jianrong Li Key Laboratory of Food Nutrition and Safety Ministry of EducationCollege of Food Science and EngineeringTianjin University of Science and TechnologyTianjin 300457China College of Food Science and Technology Bohai UniversityNational R&D Branch Center of Surimi and Surimi Products ProcessingJinzhou 121013China

A Pickering emulsion based on sodium starch octenyl succinate(SSOS)was prepared and its effects on the physicochemical properties of hairtail myofibrillar protein gels(MPGs)subjected to multiple freeze-thaw(F-T)cycles were *** whiteness,water-holding capacity,storage modulus(G')and texture properties of the MPGs were significantly improved by adding 1%-2%Pickering emulsion(P<0.05).Meanwhile,Raman spectral analysis demonstrated that Pickering emulsion promoted the transformation of secondary structure,enhanced hydrogen bonds and hydrophobic interactions,and promoted the transition of disulfide bond conformation from g-g-g to g-g-t and *** an emulsion concentration of 2%,theα-helix content decreased by 10.37%,while theβ-sheet content increased by 7.94%,compared to the *** F-T cycles,the structure of the MPGs was destroyed,with an increase in hardness and a decrease in whiteness and water-holding capacity,however,the quality degradation of MPGs was reduced with 1%-2%Pickering *** findings demonstrated that SSOS-Pickering emulsions,as potential fat substitutes,can enhance the gel properties and the F-T stability of MPGs.

关键词： Pickering emulsion Myofibrillar protein Gel properties Freeze-thaw stability Intermolecular interactions

基于高斯过程回归的中压配电网雷击过电压预测方法

在线全文

学校读者我要写书评

暂无评论

电瓷避雷器 2024年第1期 19-28页

作者：王晖南高强胡非丁涛国网山西省电力公司太原030000 国网新疆营销服务中心乌鲁木齐830000 西安交通大学电气与电子信息工程学院西安710000

准确评估雷击过电压对合理绝缘配合研究至关重要,基于此,提出了一种基于机器学习的高斯过程回归模型,用于预测大范围地电阻率和介电常数下的雷击过电压。即采用二维时域有限差分技术,结合地面场线耦合模型,计算了雷击过电压。考虑到输... 详细信息

准确评估雷击过电压对合理绝缘配合研究至关重要,基于此,提出了一种基于机器学习的高斯过程回归模型,用于预测大范围地电阻率和介电常数下的雷击过电压。即采用二维时域有限差分技术,结合地面场线耦合模型,计算了雷击过电压。考虑到输入空间的可变性,考虑了7个预测变量,即电阻率、介电常数、回击速度、闪点距离、回击峰值电流、前沿时间和架空线路的高度,以确定响应变量,即雷击过电压。因此,高斯过程回归模型的训练是使用从二维时域有限差分技术获得的雷击过电压对第一次和随后的雷击进行的。利用均方根误差对模型的估计精度进行了评估,表明指数核函数在描述协方差方面的误差最小。最后,通过将预测模型与二维时域有限差分技术生成的随机测试案例进行对比,评估预测性能,预测结果与时域有限差分法的预测结果吻合较好,验证了所提方法的有效性。

关键词：感应过电压雷击有损接地架空线路

TiO_(2)/TiN异质结内建电场的构筑及多硫化锂催化转化性能研究

在线全文

学校读者我要写书评

暂无评论

储能科学与技术 2024年第8期13卷 2499-2510页

作者：杜陈强聂周缓王慧楠张纪伟张经纬河南大学纳米科学与工程研究院河南开封475004

锂硫电池因具有较高理论容量和能量密度,成为最有前景的下一代电池体系之一。正极材料存在导电性差和多硫化锂转化反应动力学缓慢等问题引起严重的穿梭效应,致使硫利用率低、功率密度小、循环寿命短,严重制约了锂硫电池商业化进程。异... 详细信息

锂硫电池因具有较高理论容量和能量密度,成为最有前景的下一代电池体系之一。正极材料存在导电性差和多硫化锂转化反应动力学缓慢等问题引起严重的穿梭效应,致使硫利用率低、功率密度小、循环寿命短,严重制约了锂硫电池商业化进程。异质结复合材料具有丰富的活性位点和催化活性,能够催化多硫化锂氧化还原反应,然而其对多硫化锂催化转化机制仍不清晰。本工作以原位构建球形TiO_(2)/TiN异质结复合材料为模型,研究异质界面结构与其对多硫化锂的“吸附-催化-转化”行为,试图解决上述问题。采用多硫化锂吸附实验、X射线光电子能谱分析、紫外可见光谱分析、恒电流充放电测试和循环伏安测试等手段,研究异质界面内建电场形成机理及其对锂硫电池电化学性能的影响。结果表明,Ti O_(2)/TiN异质结界面形成由TiN指向TiO_(2)的空间电荷区并构成内建电场。异质结内建电场显著改善多硫化锂锚定能力,加速Li^(+)快速传输,提高多硫化锂向Li_(2)S转化能力。TiO_(2)/TiN异质结复合材料组装的锂硫电池倍率循环测试结果表明在0.05 C电流密度下初始放电比容量高达1070 mAh/g,多次循环后1C电流密度下容量仍保持60.7%。变温循环伏安测试结果表明TiO_(2)/TiN异质结复合材料将Li_(2)S转化反应活化能降低至2.73 kJ/mol。本工作为锂硫电池正极复合材料的设计和推动锂硫电池进一步发展提供新思路。

关键词：锂硫电池多硫化锂穿梭效应异质结内建电场

不同温度下PYX在3种溶剂中的结晶形貌预测

维普期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

中北大学学报（自然科学版） 2024年第1期45卷 83-89页

作者：雷超刚吕天成胡立双刘洋张添淇刘逸夫王慧男中北大学环境与安全工程学院山西太原030051 湖北航鹏化学动力科技有限责任公司湖北襄阳441003

本文应用分子动力学模拟方法,模拟了2,6-二苦氨基-3,5-二硝基吡啶(PYX)在真空中的晶体形貌。通过计算溶剂和晶面之间的相互作用能,修正了附着能,模拟出5种温度条件下PYX在3种溶剂(二甲基亚砜(DMSO)、N,N-二甲基甲酰胺(DMF)、N-甲基吡咯... 详细信息

本文应用分子动力学模拟方法,模拟了2,6-二苦氨基-3,5-二硝基吡啶(PYX)在真空中的晶体形貌。通过计算溶剂和晶面之间的相互作用能,修正了附着能,模拟出5种温度条件下PYX在3种溶剂(二甲基亚砜(DMSO)、N,N-二甲基甲酰胺(DMF)、N-甲基吡咯烷酮(NMP))中的晶体形貌。结果表明:PYX在真空条件下主要显露的3个晶面分别是(0 1 1)晶面、(1 0 1)晶面、(1 1 0)晶面,总面积占比为95.975%,PYX在真空中的晶体形貌是较为规整的多面体,纵横比为1.388。PYX各晶面与3种不同溶剂的相互作用能差异较大,导致各晶面修正附着能的差异较大,而且不同温度对晶面能量的影响也较显著,导致形貌各不相同。其中,298 K时NMP溶剂的作用和418 K时DMF溶剂的作用,均促使PYX呈现出类球体,纵横比分别是1.311和1.322,为制备PYX球晶提供方向。

关键词：耐热炸药 2,6-二苦氨基-3,5-二硝基吡啶(PYX) 温度晶体形貌分子动力学

基于网络药理学和实验验证探究黄精增强免疫功能的作用机制

在线全文

学校读者我要写书评

暂无评论

世界中医药 2024年第12期19卷 1730-1736页

作者：岳珠珠石双慧张婧秋魏晓彤姜明瑞王梦琳王志成王慧楠阮意丹王英姿北京中医药大学中药学院北京102488

目的:探究黄精增强免疫功能的作用机制。方法:使用中药系统药理学数据库与分析平台(TCMSP)收集黄精活性成分,通过SwissTargetPrediction数据库获得对应靶点基因。使用GeneCards、DrugBank数据库筛选免疫抑制(IS)相关靶点基因,并通过Venn... 详细信息

目的:探究黄精增强免疫功能的作用机制。方法:使用中药系统药理学数据库与分析平台(TCMSP)收集黄精活性成分,通过SwissTargetPrediction数据库获得对应靶点基因。使用GeneCards、DrugBank数据库筛选免疫抑制(IS)相关靶点基因,并通过Venny数据库获得与黄精靶点基因的交集基因。使用String数据库构建蛋白质-蛋白质相互作用(PPI)网络,使用Cytoscape软件构建“黄精-有效成分-靶基因-免疫抑制”网络,利用Metascape数据库对交集基因进行基因本体(GO)富集分析以及京都基因和基因组百科全书(KEGG)富集分析,使用分子对接对有效成分和靶点进行验证。体外细胞试验采用脂多糖(LPS)诱导的RAW264.7细胞模型,通过MTT法检测不同浓度黄精提取物对细胞的毒性反应;采用Griess法检测黄精提取物对细胞中一氧化氮(NO)的影响。结果:经过筛选,ESR1、SRC、IGF1R、PTGS1、PTGS2等均参与了多个关键生物过程和关键通路。GO富集表明,细胞活化、炎症反应、细胞对应激的反应等为主要生物过程;KEGG富集表明,糖尿病并发症中的AGE-RAGE信号通路、AMPK、核因子κB信号通路等是关键通路。分子对接结果显示有效成分与核心靶点对接结果良好。体外试验结果显示,与LPS组比较,50,200,800μg/mL的黄精提取物组RAW264.7细胞中NO生成量均显著降低(均P<0.01)。结论:本研究初步预测了黄精增强免疫功能的ESR1、SRC等作用靶点和AMPK、核因子κB等信号通路,并结合Griess法表明黄精可通过调控炎症模型RAW264.7细胞NO的释放来发挥免疫作用。

关键词：网络药理学黄精增强免疫有效成分靶点 RAW264.7细胞作用机制

同方期刊数据库

Highly active copper-intercalated weakly crystallized δ-MnO_(2) for low-temperature oxidation of CO in dry and humid air

在线全文

学校读者我要写书评

暂无评论

Frontiers of Environmental Science & Engineering 2024年第5期18卷 127-136页

作者： Hao Zhang huinan Li Pengyi Zhang Tingxia Hu Xianjie wang State Key Joint Laboratory of Environment Simulation and Pollution Control School of EnvironmentTsinghua UniversityBeijing100084China Beijing Key Laboratory for Indoor Air Quality Evaluation and Control Beijing100084China Midea Corporate Research Center Foshan528311China

Copper intercalated birnessite MnO_(2)(δ-MnO_(2))with weak crystallinity and high specific surface area(421 m^(2)/g)was synthesized by a one-pot redox method and investigated for low-temperature CO *** molar ratio of Cu/Mn was as high as 0.37,which greatly weakened the Mn-O bond and created a lot of low-temperature active oxygen *** situ DRIFTS revealed strong bonding of copper ions with ***-synthesized MnO_(2)-150Cu achieved 100%conversion of 250 ppm CO in normal air(3.1 ppm H_(2)O)even at−10°C under the weight-hourly space velocity(WHSV)of 150 L/(g·h).In addition,it showed high oxygen storage capacity to oxidize CO in inert *** the concurrent moisture in air significantly inhibited CO adsorption and its conversion at ambient temperature,MnO_(2)-150Cu could stably convert CO in 1.3%moisture air at 70°C owing to its great low-temperature activity and reduced competitive adsorption of water with increased *** study discovers the excellent low-temperature activity of weakly crystallized δ-MnO_(2) induced by high content intercalated copper ions.

关键词： CO oxidation Birnessite Interlayer copper Low-temperature Oxygen storage capacity

Guipi decoction effects on brain somatostatin levels and receptor mRNA expression in rats with spleen deficiency

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2008年第2期3卷 200-203页

作者： huinan Qian Le wang Libo Shen Xueqin Hu Research Center for Traditional Chinese Medicine Constitution and Reproductive Medicine Beijing University of Chinese Medicine Beijing100029 China

BACKGROUND： Somatostatin is abundant in the hypothalamus, cerebral cortex, limbic system, and mesencephalon. Somatostatin mRNA expression in the brain of rats with spleen deficiency is noticeably reduced, as well as attenuation of cognitive function. OBJECTIVE： To observe the interventional effect of Guipi decoction on somatostatin level and somatostatin receptor 1 （SSTRl） mRNA expression in different encephalic regions of rats with spleen deficiency, and to compare the interventional effects of Guipi decoction, Chaihu Shugan powder, and Tianwang Buxin pellet. DESIGN： A randomized controlled observation. SETTING： Basic Medical College, Beijing University of Traditional Chinese Medicine. MATERIALS： Fifty adult Wistar male rats, of clean grade, weighing （160 ± 10） g, were provided by Beijing Weitong Lihua Laboratory Animal Technology Co., Ltd. The protocol was performed in accordance with ethical guidelines for the use and care of animals. Somatostatin 1 polyclonal anti-rabbit antibody and SSTRl in situ hybridization kit were provided by Department of Neuroanatomy, Shanghai Second Military Medical University of Chinese PLA. The drug for developing rat models of spleen deficiency was composed of Dahuang, Houpu and Zhishi, and prepared at 2：1：1. Guipi decoction, Chaihu Shugan powder, and Tianwang Buxin pellet recipes were made according to previous studies. METHODS： This study was performed at the Basic Medical College, Beijing University of Traditional Chinese Medicine from March 2002 to March 2005. The rats were randomly divided into 5 groups, with 10 rats in each group： normal, model, Guipi decoction, Chaihu Shugan ***, and Tianwang Buxin pellet groups. Rat models of the latter 4 groups were developed by methods of purgation with bitter and cold nature drugs, improper diet, and overstrain. The rats received 7.5 g/kg of the drugs each morning and were fasted every other day, but were allowed free access to water at all times. The rats were forced to swim in 25

关键词： somatostatin receptor mRNA expression model of spleen deficiency somatostatin Guipi decoction cognitive function

Effect of SSOS-based Pickering emulsion on the physicochemical properties of hairtail myofibrillar protein gel subjected to multiple freeze-thaw cycles

在线全文

学校读者我要写书评

暂无评论

Food Science and Human Wellness 2022年

作者： huinan wang Jiaxin Zhang Xinran Liu Jinxiang wang Xuepeng Li Jianrong Li College of Food Science and Technology， Bohai University， National R&D Branch Center of Surimi and Surimi Products Processing Key Laboratory of Food Nutrition and Safety， Ministry of Education， College of Food Science and Engineering， Tianjin University of Science and Technology

A Pickering emulsion based on sodium starch octenyl succinate (SSOS) was prepared and its effects on the physicochemical properties of hairtail myofibrillar protein gels (MPGs) subjected to multiple freeze-thaw (F-T) cycles were investigated. The whiteness， water-holding capacity， storage modulus (G’) and texture properties of the MPGs were significantly improved by adding 1%-2% Pickering emulsion (P < 0.05). Meanwhile， Raman spectral analysis demonstrated that Pickering emulsion promoted the transformation of secondary structure， enhanced hydrogen bonds and hydrophobic interactions， and promoted the transition of disulfide bond conformation from g-g-g to g-g-t and t-g-t. At an emulsion concentration of 2%， the α-helix content decreased by 10.37%， while the β-sheet content increased by 7.94%， compared to the *** F-T cycles， the structure of the MPGs was destroyed， with an increase in hardness and a decrease in whiteness and water-holding capacity， however， the quality degradation of MPGs was reduced with 1%–2% Pickering emulsion. These findings demonstrated that SSOS-Pickering emulsions， as potential fat substitutes， can enhance the gel properties and the F-T stability of MPGs.

关键词：

正交试验优选千金子制霜工艺及制霜前后脂肪油成分变化分析

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

中国药事 2024年第5期38卷 567-574页

作者：魏晓彤石双慧王梦琳马思媛胡宇峰姜明瑞张婧秋王慧楠梁少国王英姿北京中医药大学北京102488

目的:优选得到千金子最佳机械压榨制霜工艺,明确其工艺参数,并分析制霜前后千金子脂肪油成分的变化情况。方法:以2020年版《中华人民共和国药典》中规定的千金子霜外观性状和脂肪油含量作为评价指标,采用L9(34)正交试验法优选千金子机... 详细信息

目的:优选得到千金子最佳机械压榨制霜工艺,明确其工艺参数,并分析制霜前后千金子脂肪油成分的变化情况。方法:以2020年版《中华人民共和国药典》中规定的千金子霜外观性状和脂肪油含量作为评价指标,采用L9(34)正交试验法优选千金子机械压榨制霜工艺的制霜温度、压制时间和制霜压力,以确定千金子最佳机械压榨制霜工艺;采用气相色谱-质谱联用(GC-MS)技术对千金子制霜前后脂肪油成分进行分析。结果:优选得到最佳机械压榨制霜工艺条件:取千金子种仁碾成泥状(粒度约为40~60目),在50℃、50 MPa的压力下压制1次,压制时间为10 min。千金子生品和霜品脂肪油中共检出14种共有脂肪酸甲酯,制霜前后脂肪油中脂肪酸成分组成基本一致,相对含量略有差别,但变化不大。结论:优选得到的千金子机械压榨制霜工艺稳定可靠,简便易行,可为千金子霜饮片生产和质量控制提供参考。

关键词：千金子炮制工艺正交试验脂肪油气相色谱-质谱联用

Atomically Dispersed Ruthenium Catalysts with Open Hollow Structure for Lithium-Oxygen Batteries

在线全文

学校读者我要写书评

暂无评论

Nano-Micro Letters 2024年第2期16卷 154-164页

作者： Xin Chen Yu Zhang Chang Chen huinan Li Yuran Lin Ke Yu Caiyun Nan Chen Chen Beijing Advanced Innovation Center for Materials Genome Engineering Institute of Solid State ChemistryUniversity of Science and Technology BeijingBeijing 100083People’s Republic of China Engineering Research Center of Advanced Rare Earth Materials Department of ChemistryTsinghua UniversityBeijing 100084People’s Republic of China Beijing Key Laboratory of Energy Conversion and Storage Materials Institution College of ChemistryBeijing Normal UniversityBeijing 100875People’s Republic of China

Lithium–oxygen battery with ultrahigh theoretical energy density is considered a highly competitive next-generation energy storage device,but its practical application is severely hindered by issues such as difficult decomposition of discharge products at ***,we have developed N-doped carbon anchored atomically dispersed Ru sites cathode catalyst with open hollow structure(h-RuNC)for Lithium–oxygen *** one hand,the abundance of atomically dispersed Ru sites can effectively catalyze the formation and decomposition of discharge products,thereby greatly enhancing the redox *** the other hand,the open hollow structure not only enhances the mass activity of atomically dispersed Ru sites but also improves the diffusion efficiency of catalytic ***,the excellent activity from atomically dispersed Ru sites and the enhanced diffusion from open hollow structure respectively improve the redox kinetics and cycling stability,ultimately achieving a high-performance lithium–oxygen battery.

关键词： Atomically dispersed Open hollow structure Discharge product Lithium Oxygen battery