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Certificateless broadcast multi-signature for network coding

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Frontiers of Information Technology & Electronic Engineering 2022年第9期23卷 1369-1377页

作者： huifang yu Zhewei QI School of Cyberspace Security Xi’an University of Posts and TelecommunicationsXi’an710121China

Network coding can save wireless network resources and is very fast in comparison with traditional *** real application scenarios,network coding is vulnerable to pollution attacks and forgery *** solve these problems,the certificateless broadcast multi-signature for network coding(NC-CLBMS)method is devised,where each source node user generates a multisignature about the message vector,and the intermediate node linearly combines the received ***-CLBMS is a multi-source multi-signature method with anti-pollution and anti-forgery advantages;moreover,it has a fixed signature length and its computation efficiency is very ***-CLBMS has extensive application prospects in unmanned aerial vehicle(UAV)communication networks,fifth-generation wireless networks,wireless sensor networks,mobile wireless networks,and Internet of Vehicles.

关键词： Network coding Certificateless multi-signature Linear combination Homomorphic hash function

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瑞芬太尼联合丙泊酚应用于剖宫产的麻醉效果

实用妇科内分泌电子杂志 2024年第9期11卷 35-37页

作者：余慧芳澧县人民医院麻醉科湖南常德415500

目的探讨瑞芬太尼联合丙泊酚应用于剖宫产的麻醉效果。方法选取本院75例剖宫产产妇为研究对象,随机分为对照组37例和试验组38例,对照组接受芬太尼联合丙泊酚进行麻醉,试验组接受瑞芬太尼联合丙泊酚进行麻醉。比较两组麻醉前、切皮时、... 详细信息

目的探讨瑞芬太尼联合丙泊酚应用于剖宫产的麻醉效果。方法选取本院75例剖宫产产妇为研究对象,随机分为对照组37例和试验组38例,对照组接受芬太尼联合丙泊酚进行麻醉,试验组接受瑞芬太尼联合丙泊酚进行麻醉。比较两组麻醉前、切皮时、娩出时的平均动脉压、心率,胎儿娩出后1min、5min的新生儿Apgar评分及术后不良反应发生情况。结果麻醉前、切皮时、娩出时,两组平均动脉压、心率比较差异无统计学意义(P>0.05);试验组胎儿娩出后5min的新生儿Apgar评分高于对照组,差异有统计学意义(P0.05)。结论瑞芬太尼联合丙泊酚用于剖宫产进行麻醉,能提高新生儿Apgar评分,且对患者血流动力学和不良反应无明显影响。

关键词：剖宫产瑞芬太尼丙泊酚血流动力学

预防性刑法的正当性及其限度:基于合宪性的检视

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青少年犯罪问题 2024年第4期 79-92页

作者：陈俊秀余惠芳福州大学中国社会科学院法学研究所贵州省社会科学院

以控制风险、维护安全为内生动力的预防性刑法,在刑事立法中主要表现在恐怖主义、经济、网络、药品及环境领域。这些领域的刑事立法存在其正当性根基:外部根基体现在当代社会的安全需求及相关前置规范的不足,内部根基体现于机能主义刑... 详细信息

以控制风险、维护安全为内生动力的预防性刑法,在刑事立法中主要表现在恐怖主义、经济、网络、药品及环境领域。这些领域的刑事立法存在其正当性根基:外部根基体现在当代社会的安全需求及相关前置规范的不足,内部根基体现于机能主义刑法观的催生及刑法体系的刑事政策化。宪法作为法秩序的规范框架,可为预防性刑法的正当性及其限度提供评价依据。预防性刑法保护安全及秩序的同时,也对公民的自由权利构成限制。然而,这种限制在形式上应遵循立法权限和立法程序,在实质上符合目的正当性、适当性、必要性以及均衡性要求。预防性刑法的合宪性审查难题在于均衡性,如何把握均衡性的限度是厘清预防性刑法界限的关键。立法者应遵循法律保留的差异性处理,确保预防性刑法所配置的刑罚和行为的风险程度相适应。同时,贯通以基本权利为内核的法益保护,从而为预防性刑法划界。

关键词：预防性刑法基本权利比例原则合宪性调控

三七茎叶总皂苷促血管新生抗缺血性脑卒中的作用机制

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中草药 2024年第14期55卷 4735-4746页

作者：余慧芳肖海燕谢皓辰刘树森刘金羽王敏孙桂波中国医学科学院北京协和医学院药用植物研究所北京100193 哈尔滨商业大学药学院黑龙江哈尔滨150076 广东药科大学中药学院广东广州510006

目的探究三七茎叶总皂苷改善缺血性脑卒中、促进缺血性脑卒中损伤后血管新生作用及机制。方法采用网络药理学技术预测三七茎叶总皂苷促进缺血性脑卒中损伤后血管新生可能的机制,利用分子对接技术对筛选出的核心靶点与主要成分的结合进... 详细信息

目的探究三七茎叶总皂苷改善缺血性脑卒中、促进缺血性脑卒中损伤后血管新生作用及机制。方法采用网络药理学技术预测三七茎叶总皂苷促进缺血性脑卒中损伤后血管新生可能的机制,利用分子对接技术对筛选出的核心靶点与主要成分的结合进行初步验证。雄性SD大鼠随机分为假手术组、模型组及三七茎叶总皂苷低、中、高剂量(73、146、292mg/kg)组和3-正丁基苯酞(3-n-butylphthalide,NBP,60 mg/kg)组,每组20只。建立大鼠脑中动脉阻塞/再灌注(middle cerebral artery occlusion/reperfusion,MCAO/R)模型,给药7 d后取材。每隔1 d对大鼠进行神经功能评分;通过2,3,5-氯化三苯基四氮唑(2,3,5-triphenyltetrazolium chloride,TTC)染色、苏木素-伊红(hematoxylin-eosin,HE)染色观察大鼠脑梗死体积及脑神经细胞形态状况;通过激光多普勒血流仪观察大鼠梗死脑侧血流恢复情况;通过光学相干断层扫描血管成像观察大鼠脑微血管新生状况;通过ELISA和Western blotting测定与血管新生相关蛋白表达。结果网络药理学分析显示,共收集到60个三七茎叶总皂苷活性成分和297个关键靶点,与血管新生和缺血性脑卒中取交集后得到64个交集靶点,并且三七茎叶总皂苷主要成分与这些核心靶点均有较好结合力。三七茎叶总皂苷促进血管新生改善缺血性脑卒中的关键通路主要富集在磷脂酰肌醇3-激酶(phosphatidylinositol 3-kinase,PI3K)/蛋白激酶B(protein kinase B,Akt)、缺氧诱导因子-1α(hypoxia inducible factor-1α,HIF-1α)等通路。动物实验结果显示,与模型组比较,三七茎叶总皂苷能够显著降低MCAO/R大鼠神经功能评分(P<0.01),改善大鼠神经功能,降低大脑梗死体积(P<0.01、0.001),减少脑组织损伤,恢复梗死脑侧脑血流(P<0.05、0.01、0.001),促进梗死脑侧皮层微血管密度(P<0.05、0.01、0.001),提高血管内皮生长因子(vascular endothelial growth factor,VEGF)、碱性成纤维细胞生长因子(basic fibroblast growth factor,bFGF)水平和HIF-1α、PI3K、p-Akt/Akt蛋白表达(P<0.05、0.01、0.001)。结论三七茎叶总皂苷能够显著改善MCAO/R大鼠脑损伤,有效促进MCAO/R大鼠缺血脑区血管新生,促血管新生机制可能与提高MCAO/R大鼠大脑中VEGF、bFGF、HIF-1α表达和激活PI3K/Akt通路有关。

关键词：三七茎叶总皂苷缺血性脑卒中血管新生网络药理学缺氧诱导因子-1α 磷脂酰肌醇3-激酶/蛋白激酶B通路人参皂苷Rb_(1) 人参皂苷Rd 人参皂苷Rg_(1) 人参皂苷Re 三七皂苷R_(1)

Certificateless network coding proxy signatures from lattice

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Frontiers of Computer Science 2023年第5期17卷 145-152页

作者： huifang yu Ning WANG School of Cyberspace Security Xi’an University of Posts&TelecommunicationsXi’an 710121China

Network coding can improve the information transmission efficiency and reduces the network resource consumption,so it is a very good platform for information *** proxy signatures are widely applied in information security ***,certificateless proxy signatures based on classical number theory are not suitable for the network coding environment and cannot resist the quantum computing *** view of this,we construct certificateless network coding proxy signatures from lattice(LCL-NCPS).LCL-NCPS is new multi-source signature scheme which has the characteristics of anti-quantum,antipollution and *** LCL-NCPS,each source node user can output a message vector to intermediate node and sink node,and the message vectors from different source nodes will be linearly combined to achieve the aim of improving the network transmission rate and network *** terms of efficiency analysis of space dimension,LCL-NCPS can obtain the lower computation complexity by reducing the dimension of proxy *** terms of efficiency analysis of time dimension,LCL-NCPS has higher computation efficiency in signature and verification.

关键词： lattice multi-source signature scheme proxy signature post-quantum

花椰菜“坐球高度”性状的主基因+多基因遗传分析

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浙江农业学报 2024年第3期36卷 527-533页

作者：蔡诗怡虞慧芳王建升祝彪沈钰森顾宏辉盛小光浙江农林大学园艺科学学院浙江杭州311300 浙江省农业科学院蔬菜研究所浙江杭州310021

“坐球高度”是评价花椰菜品种是否适合机械化采收的重要农艺性状之一。为了解析花椰菜“坐球高度”性状的遗传规律,使用早熟、紧实型花椰菜F 7代自交系ZAASC4101与芥蓝F_(6)代自交系ZAASJ1401为亲本构建了包括P_(1)、P_(2)、F_(1)、F_... 详细信息

“坐球高度”是评价花椰菜品种是否适合机械化采收的重要农艺性状之一。为了解析花椰菜“坐球高度”性状的遗传规律,使用早熟、紧实型花椰菜F 7代自交系ZAASC4101与芥蓝F_(6)代自交系ZAASJ1401为亲本构建了包括P_(1)、P_(2)、F_(1)、F_(2)、B_(1)、B_(2)的6个联合世代群体,利用主茎高度(六世代群体)和叶痕间距(F_(2)群体)两个指标来锚定“坐球高度”性状。研究结果表明,F_(2)群体中主茎高度与叶痕间距数值呈极显著相关(相关系数为0.652),并且这两个指标均为连续性的近似正态分布,符合数量遗传的特征;主茎高度的六世代群体遗传分析和叶痕间距的F_(2)群体遗传分析结果均表明,花椰菜“坐球高度”性状的最适遗传模型为:两对加性显性上位性主基因+加性显性上位性多基因遗传模型,表明该性状主要受两对主基因+多个微效基因的控制,并且遗传率达到97.84%。因此,可以利用连锁分子标记在早期世代对花椰菜“坐球高度”性状进行辅助选择和遗传改良。综上,本研究结果为进一步定位和挖掘控制花椰菜“坐球高度”性状的关键基因,最终利用生物技术手段育成适宜机械化采收的花椰菜新品种奠定了前期研究基础。

关键词：花椰菜坐球高度六世代群体主基因+多基因遗传分析数量性状

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Post-quantum blind signcryption scheme from lattice

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Frontiers of Information Technology & Electronic Engineering 2021年第6期22卷 891-901页

作者： huifang yu Lu BAI School of Cyberspace Security Xi’an University of Posts and TelecommunicationsXi’an 710121China

Blind signcryption(BSC) can guarantee the blindness and untrackability of signcrypted messages, and moreover, it provides simultaneous unforgeability and confidentiality. Most traditional BSC schemes are based on the number theory. However, with the rapid development of quantum computing, traditional BSC systems are faced with severe security threats. As promising candidate cryptosystems with the ability to resist attacks from quantum computing, lattice-based cryptosystems have attracted increasing attention in academic fields. In this paper, a post-quantum blind signcryption scheme from lattice(PQ-LBSCS) is devised by applying BSC to lattice-based cryptosystems. PQ-LBSCS inherits the advantages of the lattice-based cryptosystem and blind signcryption technique. PQ-LBSCS is provably secure under the hard assumptions of the learning with error problem and small integer solution problem in the standard model. Simulations are carried out using the Matlab tool to analyze the computational efficiency, and the simulation results show that PQ-LBSCS is more efficient than previous schemes. PQ-LBSCS has extensive application prospects in e-commerce, mobile communication, and smart cards.

关键词： Lattice-based cryptosystem Blind signcryption Post-quantum computing Learning with error assumption Small integer solution assumption

Role of inflammatory lipid and fatty acid metabolic abnormalities induced by plastic additives exposure in childhood asthma

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Journal of Environmental Sciences 2024年第3期137卷 172-180页

作者： Zhiyu Chen Fang Li Lei Fu yu Xia Ying Luo Ang Guo Xiaona Zhu huifang Zhong Qian Luo Institute of Biomedical and Health Engineering Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China University of Chinese Academy of Sciences Beijing 100049China Rheumatology&Immunology Department of Shenzhen Children’s Hospital Shenzhen 518038China Hubei Key Laboratory of Environmental and Health Effects of Persistent Toxic Substances Institute of Environment and HealthJianghan UniversityWuhan 430056China

Lipid metabolism play an essential role in occurrence and development of asthma,and it can be disturbed by phthalate esters(PAEs)and organophosphate fame retardants(OPFRs).As a chronic infammatory respiratory disease,the occurrence risk of childhood asthma is increased by PAEs and OPFRs exposure,but it remains not entirely clear how PAEs and OPFRs contribute the onset and progress of the *** have profiled the serum levels of PAEs and OPFRs congeners by liquid chromatography coupled with mass spectrometry,and its relationships with the dysregulation of lipid metabolism in asthmatic,bronchitic(acute infammation)and healthy(non-infammation)*** PAEs and nine OPFRs congeners were found in the serum of children(1–5 years old)from Shenzhen,and their total median levels were 615.16 ng/m L and 17.06 ng/m L,***,the serum levels of mono-methyl phthalate(MMP),tri-propyl phosphate(TPP)and tri-n-butyl phosphate(TNBP)were significant higher in asthmatic children than in healthy and bronchitic children as ***-one characteristic lipids and fatty acids of asthma were screened by machine-learning random forest model based on serum lipidome data,and the alterations of infammatory characteristic lipids and fatty acids including palmitic acids,12,13-Di HODE,14,21-Di HDHA,prostaglandin D2 and Lyso PA(18:2)showed significant correlated with high serum levels of MMP,TPP and *** results imply PAEs and OPFRs promote the occurrence of childhood asthma via disrupting infammatory lipid and fatty acid metabolism,and provide a novel sight for better understanding the effects of plastic additives on childhood asthma.

关键词： Phthalate esters Organophosphate fame retardants Childhood asthma Lipid and fatty acid metabolism Machine-learning random forest model Chronic airway infammation

Doping suppresses lattice distortion of vacant quadruple perovskites to activate self-trapped excitons emission

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Nano Research 2024年第4期17卷 3068-3078页

作者： Zhipeng Chen Fei Zhang Dongwen Yang huifang Ji Xu Chen Di Wu Xinjian Li yu Zhang Zhifeng Shi Key Laboratory of Materials Physics of Ministry of Education School of Physics and MicroelectronicsZhengzhou UniversityZhengzhou 450052China State Key Laboratory on Integrated Optoelectronics College of Electronic Science and EngineeringJilin UniversityChangchun 130012China

The vacancy-ordered quadruple perovskite Cs_(4)CdBi_(2)Cl_(12),as a newly-emerging lead-free perovskite system,has attracted great research interest due to its excellent stability and direct band ***,the poor luminescence performance limits its application in light-emitting diodes(LEDs)and other ***,for the first time,an Ag^(+)ion doping strategy was proposed to greatly improve the emission performance of Cs_(4)CdBi_(2)Cl_(12) synthesized by hydrothermal *** functional theory calculations combined with experimental results evidence that the weak orange emission from Cs_(4)CdBi_(2)Cl_(12) is attributed to the phonon scattering and energy level crossing due to the large lattice distortion under excited ***,Ag^(+)ion doping breaks the intrinsic crystal field environment of Cs_(4)CdBi_(2)Cl_(12),suppresses the crossover between ground and excited states,and reduces the energy loss in the form of nonradiative *** a critical doping amount of 0.8%,the emission intensity of Cs_(4)CdBi_(2)Cl_(12):Ag^(+)reaches the maximum,about eight times that of the pristine ***,the doped Cs_(4)CdBi_(2)Cl_(12) still maintains excellent stability against heat,ultraviolet irradiation,and environmental oxygen/*** above advantages make it possible for this material to be used as solid-state phosphors for white LEDs applications,and the Commission International de I’Eclairage color coordinates of(0.31,0.34)and high color rendering index of 90.6 were *** importantly,the white LED demonstrates remarkable operation stability in air ambient,showing almost no emission decay after a long working time for 48 *** believe that this study puts forward an effective ion-doping strategy for emission enhancement of vacancy-ordered quadruple perovskite Cs_(4)CdBi_(2)Cl_(12),highlighting its great potential as efficient emitter compatible for practical applications.

关键词： Cs_(4)CdBi_(2)Cl_(12) self-trapped excitons ion doping emission enhancement stability