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Clinical effectiveness of a pneumatic compression device combined with low-molecular-weight heparin for the prevention of deep vein thrombosis in trauma patients:A single-center retrospective cohort study

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World Journal of Emergency Medicine 2022年第3期13卷 189-195页

作者： Peng-chao Guo Nan Li hui-ming Zhong Guang-feng zhao Emergency Department the Second Affiliated Hospital of Zhejiang University School of MedicineHangzhou 310009China Plastic Surgery Department the Second Affiliated Hospital of Zhejiang University School of MedicineHangzhou 310009China

BACKGROUND:To investigate the clinical effectiveness of a pneumatic compression device(PCD)combined with low-molecular-weight heparin(LMWH)for the prevention and treatment of deep vein thrombosis(DVT)in trauma ***:This study retrospectively analyzed 286 patients with mild craniocerebral injury and clavicular fractures admitted to our department from January 2016 to February *** treated with only LMWH served as the control group,and patients treated with a PCD combined with LMWH as the observation *** incidence of DVT,postoperative changes in the visual analogue scale(VAS)score,and coagulation function were observed and compared between the two *** the influence of other single factors,binary logistic regression analysis was used to evaluate the use of a PCD in the patient’s postoperative coagulation ***:After excluding 34 patients who did not meet the inclusion criteria,252 patients were were *** incidence of DVT in the observation group was significantly lower than that in the control group(5.6%vs.15.1%,χ^(2)=4.605,P0.05).According to logistic regression analysis,the postoperative risk of DVT in patients who received LMWH alone was 1.764 times that of patients who received LMWH+PCD(P<0.05).The area under the receiver operating characteristic(AUROC)curve of partial thromboplastin time(APTT)and platelet(PLT)were greater than 0.5,indicating that they were the influence indicators of adding PCD to prevent *** the influence of other variables,LM

关键词： Deep vein thrombosis Pneumatic compression device Low-molecular-weight heparin Trauma Logistic regression analysis

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Decision making module based on stochastic magnetic tunnel junctions

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 202-209页

作者： Yifan Miao Li zhao Yajun Zhang Zhe Yuan Center for Advanced Quantum Studies and Department of Physics Beijing Normal University Institute for Nanoelectric Devices and Quantum Computing Fudan University Interdisciplinary Center for Theoretical Physics and Information Sciences Fudan University

In biological neural systems, noise is ubiquitous but does not affect the correct decisions made in the complex cognitive ***-making in biological neural system is typically achieved by accumulating input information over a period of *** by recent developments in neurosciences, we design a decision-making module based on spintronic devices, utilizing superparamagnetic tunnel junctions as artificial neurons. The feasibility of this decision-making module is verified through circuit simulations. Taking a multi-layer perceptron as an example, the module significantly improves the accuracy of the perceptron in the handwritten digit recognition task. Furthermore, the spintronic decision-making module offers advantages over the conventional pooling methods, such as adaptive decision time, high performance and the absence of analog-to-digital conversion. The decision-making module is flexible to be integrated into artificial neural networks and provides a general yet effective solution to enhance performance against device noise.

关键词： neuromorphic computing spintronics magnetic tunnel junction neural networks

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陈旧性骨质疏松性椎体压缩骨折骨不连的修复策略:一项病例分析

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中国组织工程研究 2025年第3期29卷 538-546页

作者：赵星丞王军陆明上海市公共卫生临床中心骨科上海市201508

背景:腰椎骨质疏松性压缩性骨折患者的脊柱和骨盆矢状位参数存在不同程度改变,将导致全脊柱/腰椎矢状面发生失平衡和再平衡。如果初次骨质疏松性椎体压缩骨折没有得到及时治疗,随着时间的推移将发展为陈旧性骨质疏松性椎体压缩骨折骨不... 详细信息

背景:腰椎骨质疏松性压缩性骨折患者的脊柱和骨盆矢状位参数存在不同程度改变,将导致全脊柱/腰椎矢状面发生失平衡和再平衡。如果初次骨质疏松性椎体压缩骨折没有得到及时治疗,随着时间的推移将发展为陈旧性骨质疏松性椎体压缩骨折骨不连。目的:观察陈旧性骨质疏松性腰椎体压缩骨折骨不连9例患者行经皮椎体成形(PVP)术后的修复效果。方法:回顾性分析2018年9月至2022年8月上海市公共卫生临床中心骨科收治的陈旧性老年骨质疏松性腰椎椎体压缩性骨折骨不连经皮椎体成形术后术椎再骨折患者9例的临床资料,所有患者均采用经皮椎体成形行再翻修治疗,同时规律进行抗骨质疏松治疗和康复训练。出院前及随访时复查患者的腰椎X射线平片及三维CT检测结果,评价骨水泥弥散情况,记录患者术前、术后、随访时的目测类比评分、腰椎Oswetry功能障碍指数(ODI评分)及Roussouly腰椎功能分型变化。结果与结论:①9例患者术后随访时均未发生神经损伤、感染、骨水泥椎管内渗漏、肺栓塞及过敏性休克等严重手术并发症,均未发生骨水泥相关的不良反应。有1例患者术后2年感染COVID-19致呼吸功能衰竭死亡。②术椎再骨折患者术后疼痛目测类比评分和ODI评分均显著低于翻修术前,末次随访经皮椎体成形翻修术后患者Roussouly腰椎功能分型显著改善;末次随访测量术椎椎体高度变化与术前比较无显著性意义。③上述结果提示,对陈旧性骨质疏松性腰椎体压缩骨折骨不连行经皮椎体成形治疗的患者而言,适量骨水泥注入和有效骨水泥弥散具有明显缓解术后疼痛作用,规律抗骨质疏松和术后有效康复训练有助于患者术后腰椎功能恢复。

关键词：骨质疏松经皮椎体成形骨水泥注入技术椎体成形术椎再骨折 Roussouly腰椎功能分型应力集中区

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One-Pot Synthesis of 4-Aryl-NH-1,2,3-Triazoles through Three- Component Reaction of Aldehydes, Nitroalkanes and NaN3

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Chinese Journal of Chemistry 2017年第12期35卷 1808-1812页

作者： Rongrong hui Mina zhao ming Chen Zhihui Ren Zhenghui Guan Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education Department of Chemistry & Materials Science Northwest University Xi'an Shaanxi 710127 China Shaanxi Key Laboratory of Phytochemistry College of Chemistry and Chemical Engineering Baoji University of Arts and Sciences Baoji Shaanxi 721013 China

A one-pot three-component reaction of aldehydes, nitroalkanes and NaN3 for the synthesis ofNH-1,2,3-triazoles has been developed. The reaction provides a safe, efficient and step-economic approach for the synthesis of... 详细信息

关键词： aldehydes sodium azide one-pot three-component reaction NH-1,2,3-triazoles

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One-year outcomes of intravitreal conbercept combined rescue therapy for polypoidal choroidal vasculopathy in a Chinese population: a real-life clinical data

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International Journal of Ophthalmology(English edition) 2019年第1期12卷 51-57页

作者： hui-Jun Qi En-Zhong Jin ming-Wei zhao Department of Ophthalmology Ophthalmology & Optometry CenterPeking University People’s HospitalBeijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases

AIM: To evaluate the real-life clinical outcomes of intravitreal injection of conbercept combined rescue therapy for polypoidal choroidal vasculopathy(PCV). METHODS: This was an open label, single center, and interventional study. All enrolled patients were treated initially with three consecutive monthly intravitreal conbercept injections(0.5 mg). Additional conbercept injections were administered upon substantial polyp regression with improved visual acuity(VA). Eyes with partial or no polyp regression and poor VA were rescue treated with photodynamic therapy(PDT) for subfoveal polyps or thermal laser photocoagulation for extrafoveal polyps. Best-corrected visual acuity(BCVA), central foveal thickness(CFT) and polyp regression were observed as primary outcomes. Side effects were also collected during the follow-up period. RESULTS: A total of 56 eyes(56 patients) with PCV were included. BCVA increased significantly from the baseline of 43.52±24.21 letters to 55.88±21.94 letters(P<0.001) at 12 mo, while CFT decreased significantly from 457.41±207.86 μm to 247.98±127.08 μm(P<0.001). All patients showed polyp regression. Twenty-three eyes achieved complete polyp regression after the three initial injections, which increased to 44 eyes at 12 mo. Seventeen eyes underwent rescue therapy, among which 2 eyes treated with PDT and 15 eyes treated with laser photocoagulation. A mean of 4.30±1.43 injections were given per eye. No intraocular inflammation, retinal or vitreous hemorrhage, or systemic complication occurred. CONCLUSION: Conbercept is an effective and safe option for the treatment of PCV in Chinese population. The treatment regimen of three initial conbercept injections followed by additional injections or rescue therapies is efficacious for treating PCV.

关键词： conbercept anti-vascular endothelial growth factor polypoidal choroidal vasculopathy intravitreal injection laser photocoagulation photodynamic therapy

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Defective graphene as a high-efficiency Raman enhancement substrate

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Journal of Materials Science & Technology 2019年第9期35卷 1996-2002页

作者： Tong zhao Zhibo Liu Xing Xin hui-ming Cheng Wencai Ren Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China School of Material Science and Engineering University of Science and Technology of ChinaShenyang 110016China University of Chinese Academy of Sciences Shenyang 110016China Shenzhen Geim Graphene Center Tsinghua-Berkeley Shenzhen Institute (TBSI)Tsinghua University1001 Xueyuan RoadShenzhen 518055China

Pristine graphene (PG) has been demonstrated to be an excellent substrate for Raman enhancement, which is called graphene-enhanced Raman scattering. However, the chemically inert and hydrophobic surface of PG hinders the adsorption of molecules especially in aqueous solutions, and consequently limits the Raman enhanced efficiency. Here, we synthesized defective graphene (DG) films by chemical vapor deposition on Au, which has a defect density of ~2.0 ×10^11 cm^-2. The DG shows a much better wettability than PG towards dye solution. Combining with the strong adsorption ability of defects to molecules, DG shows greatly enhanced efficiency than PG with perfect lattice. For example, the detection limit for rhodamine B can reach 2×10^9 M for DG while it is on the order of 10^-7 M for PG. In addition, DG has high enhancement uniformity and the Au substrate can be reused after electrochemical bubbling transfer. These advantages suggest the great potential of the DG grown on Au for practical applications in environmental monitoring.

关键词： Defective graphene Raman enhancement Chemical vapor deposition Bubbling transfer

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Determination of uric acid in human urine by ion chromatography with conductivity detector

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Chinese Chemical Letters 2011年第3期22卷 342-345页

作者： Fu Yong zhao Zong Hua Wang hui Wang Rui zhao ming Yu Ding Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education) Department of Chemistry Tsinghua University Beijing 100084 China Laboratory of Fiber Materials and Modem Textile the Growing Base for State Key Laboratory Qingdao University Qingdao 266071 China Metrohm China Ltd. Beijing Beijing 100005 China

A simple,fast,precise and eco-friendly analytical method for the determination of uric acid（UA） in human urine by ion chromatography（IC） was *** sample pretreatment was not required,only needed centrifugation and *** separation was carried out on a cation exchange column with 2.0 mmol/L nitric acid as mobile phase at the flow-rate 1.0 mL/min.A non-suppressed conductivity detector was *** IC analysis time for one run was within 10 min under the optimized IC *** detection limits were 0.5μg/L（S/N = 3） for uric *** recovery was 100.1%while the relative standard deviation （RSD） was 1.8%from 10 measurements.

关键词： Ion chromatography Uric acid Urine

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A case of rhabdomyolysis with compartment syndrome in the right upper extremity

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World Journal of Emergency Medicine 2020年第3期11卷 185-187页

作者： hui-ming Zhong Guang-feng zhao Peng-chao Guo Emergency Department the Second Affi liated Hospital of Zhejiang University School of MedicineHangzhou 310009China

Dear editor,Acute compartment syndrome refers to a series of symptoms of muscles and nerves in the compartment of the fascia due to acute ischaemia and *** is more common in the volar and calf of the forearm.[1]Due to long-term ischaemia of muscles and nerves in the fascia,muscle necrosis and neurological dysfunction can occur,causing serious irreversible damage to the ***,rhabdomyolysis is one of the major complications in the absence of fractures or other trauma.

关键词： nerves Acute acute

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Effect of hydrogen addition on compression deformation behaviour of Ti-0.3Mo-0.8Ni alloy argon-arc welded joints

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Journal of Iron and Steel Research International 2021年第5期28卷 621-628页

作者： zhao-hui Zhang Quan-ming Liu Li Fu Hai-ying Yang Shi-feng Liu School of Metallurgical Engineering Xi'an University of Architecture and TechnologyXi'an 710055ShaanxiChina Shaanxi Key Laboratory of Friction Welding Technologies State Key Laboratory of Solidification ProcessingNorthwestern Polytechnical UniversityXi'an 710072ShaanxiChina Institute of Titanium Alloy Research Northwest Institute for Nonferrous Metal ResearchXi'an 710016ShaanxiChina

The effect of hydrogen addition on compression deformation behaviour of Ti-0.3Mo-0.8Ni alloy argon-arc welded joint has been *** mechanism of hydrogen-induced flow stress was discussed in *** results show that with increasing hydrogen content,the stretching and bending extent of fully lamellar microstructures including ot lamellas and acicular hydride continued to increase,the morphology of dynamic recrystallization(DRX)grains tended to change from approximately equiaxed to large lamellar shape,and the quantity of DRX grains and recrystallization degree of grains increased obviously.A large number of dislocations concentrated in the vicinity of the *** stress was decreased continuously with increasing hydrogen content,while peak stress of the hydrogenated 0.12 wt.% H weld zone was decreased to the minimum value and then increased slowly.A slight decrease in flow stress of the hydrogenated 0.05 wt.% H weld zone was caused by limited increase in the volume fraction of softer β***-induced DRX of a phase and improved dislocation movement by strong interaction between the hydride and dislocation directly resulted in a sharp drop in flow stress of the hydrogenated 0.12 and 0.21 wt.% H weld *** hydrogen also finitely contributed to a sharp drop in flow stress of the hydrogenated 0.12 and 0.21 wt.% H weld zone by promoted local softening,which induced continuous DRX and more movable dislocations to participate in slipping or *** reinforcement effect and plastic deformation of the hydride and solution strengthening of P phase induced by solute hydrogen finally led to the increase in flow stress of the hydrogenated 0.21 wt.% H weld zone in its true strain range from 0 to 0.36.

关键词： Titanium alloy Welded joint Hydrogen addition Compression behaviour Flow stress Evolution mechanism

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Microstructure and mechanical properties of hot-rolled V-microalloyed Al-containing medium-Mn steel

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Journal of Iron and Steel Research International 2020年第5期27卷 537-548页

作者： ming Lei Wei-jun hui Jiao-jiao Wang Yong-jian Zhang Xiao-li zhao School of Mechanical Electronic and Control EngineeringBeijing Jiaotong UniversityBeijing 100044China

The microstructure and mechanical properties of a V-microalloyed Al-containing medium-Mn steel after hot rolling and intercritical annealing(IA)are *** tested steel exhibits a fne multiphase microstructure consisting of bimodal sizes of ferrite and retained austenite plus considerable amount of fne VC and/or M3C ***-chemical phase analysis shows that about 71.0%of the total V is in VC phase and more than 93%of VC particles is less than 5 *** calculated precipitation strengthening values of VC are^347 and^234 MPa for the specimens intercritically annealed at 625 and 750℃,*** excellent combination of strength and ductility as high as^50 GPa%and yield strength(YS)of 890 MPa was obtained at intercritical temperature(TIA)of 725℃,although it does not correspond to the maximum precipitation strengthening of VC ***,it is suggested that an optimization of TIA corresponding to both excellent combination of strength and ductility and high YS should be further explored through chemical composition and IA process optimization.

关键词： Medium-Mn steel Vanadium Intercritical annealing Microstructure Mechanical property

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