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Microstructure and properties of Al–7Si–0.6Mg alloys with different Ti contents deposited by wire arc additive manufacturing

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Rare Metals 2021年第9期40卷 2530-2537页

作者： Cheng-De Li hui-min gu Wei Wang Shuai Wang Ling-Ling Ren Yu-Chun Zhai Zhen-Biao Wang Zhu ming School of Metallurgy Northeastern UniversityShenyang 110006China Research Laboratory of WAAM Process Inner Mongolia Metal Material Research InstituteNingbo 315100China Technology Department North East Industrial Materials and Metallurgy Co.Ltd.Fushun 113200China

Numerous studies have addressed the advantages of wire arc additive manufacturing for manufacturing aluminum alloys. However, the role of Ti content in aluminum alloys has rarely been discussed. Herein, the effect of Ti content on the microstructure and properties of Al–7 Si–0.6 Mg alloys was studied. The alloys were deposited via wire arc additive manufacturing and were examined through optical microscopy(OM), scanning electron microscopy(SEM), and electronic universal testing. The results show that the increase of Ti content gradually promotes the increase of the secondary dendrite arm spacing and also has an increasing tendency to form pores defect in the as-deposited alloys. The change of titanium content also affects the difference between horizontal and vertical direction properties of the alloy. The alloy with a Ti content of 0.112 wt% exhibits the best comprehensive properties. There is no difference in its horizontal and vertical direction properties. The tensile strengths, yield strengths, and elongation of this alloy(T6) along the vertical and horizontal axis are 356 and 355 MPa, 307 and308 MPa, and 8.5% and 8.0%, respectively.

关键词： Wire arc additive manufacturing Al–7Si–0.6Mg alloy Microstructure and properties Titanium

Reaction mechanism of roasting Zn_2SiO_4 using NaOH

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Transactions of Nonferrous Metals Society of China 2018年第9期28卷 1878-1886页

作者： Xiao-yi SHEN Hong-mei SHAO hui-min gu Bing CHEN Yu-chun ZHAI Pei-hua MA School of Metallurgy Northeastern UniversityShenyang 110819China Liaoning Key Laboratory for Metallurgical Sensor and Technology Northeastern UniversityShenyang 110819China School of Environmental and Chemical Engineering Shenyang Ligong UniversityShenyang 110159China Science and Technology Laboratory Academy of Environmental Sciences of Panjin CityPanjin 124401China

The reaction kinetics of roasting zinc silicate using NaOH was *** orthogonal test was employed to optimize the reaction conditions and the optimized reaction conditions were as follows:molar ratio of NaOH to Zn2SiO4 of 16:1,reaction temperature of 550°C,and reaction time of 2.5 *** order to ascertain the phases transformation and reaction processes of zinc oxide and silica,the XRD phase analysis was used to analyze the phases of these specimens roasted at different *** final phases of the specimen roasted at 600°C were Na2ZnO2,Na4SiO4,Na2ZnSiO4 and *** reaction kinetic equation of roasting was determined by the shrinking unreacted core *** to investigate the reaction mechanism,two control models of reaction rate were applied:chemical reaction at the particle surface and diffusion through the product *** results indicated that the diffusion through the product layer model described the reaction process *** apparent activation energy of the roasting was 19.77 kJ/mol.

关键词： reaction mechanism kinetics Zn2SiO4 NaOH roasting reaction process phase transformation

GPS: graph contrastive learning via multi-scale augmented views from adversarial pooling

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Science China(Information Sciences) 2025年第1期68卷 145-158页

作者： Wei JU Yiyang gu Zhengyang MAO Ziyue QIAO Yifang QIN Xiao LUO hui XIONG ming ZHANG School of Computer Science National Key Laboratory for Multimedia Information ProcessingPeking University Artificial Intelligence Thrust The Hong Kong University of Science and Technology Department of Computer Science University of California

Self-supervised graph representation learning has recently shown considerable promise in a range of fields, including bioinformatics and social networks. A large number of graph contrastive learning approaches have shown promising performance for representation learning on graphs, which train models by maximizing agreement between original graphs and their augmented views(i.e., positive views). Unfortunately, these methods usually involve pre-defined augmentation strategies based on the knowledge of human experts. Moreover, these strategies may fail to generate challenging positive views to provide sufficient supervision signals. In this paper, we present a novel approach named graph pooling contrast(GPS) to address these *** by the fact that graph pooling can adaptively coarsen the graph with the removal of redundancy, we rethink graph pooling and leverage it to automatically generate multi-scale positive views with varying emphasis on providing challenging positives and preserving semantics, i.e., strongly-augmented view and weakly-augmented view. Then, we incorporate both views into a joint contrastive learning framework with similarity learning and consistency learning, where our pooling module is adversarially trained with respect to the encoder for adversarial robustness. Experiments on twelve datasets on both graph classification and transfer learning tasks verify the superiority of the proposed method over its counterparts.

关键词： graph representation learning graph neural networks graph contrastive learning graph augmentations graph pooling

Breaking new ground in photocatalysis: lutetium texaphyrin as a trigger for pyroptosis through biomolecular photoredox reactions

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Science China Chemistry 2025年第1期68卷 1-2页

作者： Qihang Ding Mengrong He Meijia gu Department of Chemistry Korea University Department of Ultrasound Medicine Union Hospital Tongji Medical College Huazhong University of Science and Technology Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) School of Pharmaceutical Sciences Wuhan University

Malignant neoplasms consistently pose a significant threat to global public health [1,2]. In recent years, immunotherapy has demonstrated remarkable clinical success; however, its efficacy is limited by the scarcity of immune cell infiltration within tumor microenvironments. Cell pyroptosis, a gasdermin-mediated process characterized by cellular swelling,rupture, and the release of intracellular contents such as IL-1β, IL-18, ATP, HMGB1, plays a crucial role in this context[3,4].

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Pathogenesis, diagnosis, and treatment of epilepsy: electromagnetic stimulation-mediated neuromodulation therapy and new technologies

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Neural Regeneration Research 2025年第4期20卷 917-935页

作者： Dian Jiao Lai Xu Zhen gu Hua Yan Dingding Shen Xiaosong gu Academy of Medical Engineering and Translational Medicine Tianjin UniversityTianjinChina Key Laboratory of Advanced Drug Delivery Systems of Zhejiang Province College of Pharmaceutical SciencesZhejiang UniversityHangzhouZhejiang ProvinceChina Affiliated Hospital of Nantong University NantongJiangsu ProvinceChina

Epilepsy is a severe,relapsing,and multifactorial neurological *** regarding the accurate diagnosis,prognosis,and in-depth pathogenesis are crucial for the precise and effective treatment of *** pathogenesis of epilepsy is complex and involves alterations in variables such as gene expression,protein expression,ion channel activity,energy metabolites,and gut microbiota *** results are lacking for conventional treatments for *** resection of lesions,drug therapy,and non-drug interventions are mainly used in clinical practice to treat pain associated with ***-pharmacological treatments,such as a ketogenic diet,gene therapy for nerve regeneration,and neural regulation,are currently areas of research *** review provides a comprehensive overview of the pathogenesis,diagnostic methods,and treatments of *** also elaborates on the theoretical basis,treatment modes,and effects of invasive nerve stimulation in neurotherapy,including percutaneous vagus nerve stimulation,deep brain electrical stimulation,repetitive nerve electrical stimulation,in addition to non-invasive transcranial magnetic stimulation and transcranial direct current *** studies have shown that electromagnetic stimulation-mediated neuromodulation therapy can markedly improve neurological function and reduce the frequency of epileptic ***,many new technologies for the diagnosis and treatment of epilepsy are being ***,current research is mainly focused on analyzing patients’clinical manifestations and exploring relevant diagnostic and treatment methods to study the pathogenesis at a molecular level,which has led to a lack of consensus regarding the mechanisms related to the disease.

关键词： diagnosis drug treatment electroencephalography epilepsy monitoring epilepsy nerve regeneration neurostimulation non-drug interventions pathogenesis prediction

采用(NH_(4))_(2)SO_(4)焙烧-水浸工艺提高菱镁矿的利用效率

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Transactions of Nonferrous Metals Society of China 2023年第2期33卷 576-583页

作者：申晓毅黄彦翔邵鸿媚刘岩顾惠敏翟玉春东北大学冶金学院多金属共生矿生态化冶金教育部重点实验室沈阳110819 东北大学辽宁省冶金传感器及技术重点实验室沈阳110819 沈阳理工大学环境与化学工程学院沈阳110159

研究采用硫酸铵焙烧—水浸工艺提高菱镁矿的利用效率,结合XRD和TG-DTA分析以及对比硫酸铵焙烧MgO的物相变化得到焙烧过程中矿相的转化过程。实验结果表明,在菱镁矿粒度为~74μm、硫酸铵与菱镁矿物料摩尔比为1.6:1、焙烧温度为475℃和焙... 详细信息

研究采用硫酸铵焙烧—水浸工艺提高菱镁矿的利用效率,结合XRD和TG-DTA分析以及对比硫酸铵焙烧MgO的物相变化得到焙烧过程中矿相的转化过程。实验结果表明,在菱镁矿粒度为~74μm、硫酸铵与菱镁矿物料摩尔比为1.6:1、焙烧温度为475℃和焙烧时间为2 h的条件下,镁的提取率达到98.7%。反应中物相转化过程可以概括如下:MgCO_(3)先转变为(NH_(4))_(2)Mg_(2)(SO_(4))_(3),再分解得到MgSO_(4)。反应遵循化学反应和扩散混合控制机理,其表观活化能为33.02 k J/mol。

关键词：菱镁矿硫酸铵焙烧-水浸法反应过程物相转化

The dopaminergic system and Alzheimer's disease

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Neural Regeneration Research 2025年第9期20卷 2495-2512页

作者： Yuhan Zhang Yuan Liang Yixue gu International Medical College Chongqing Medical UniversityChongqingChina College of Pharmacy Chongqing Medical UniversityChongqingChina Department of Neurology The First Affiliated Hospital of Chongqing Medical UniversityChongqing Key Laboratory of NeurologyChongqingChina

Alzheimer's disease is a common neurodegenerative disorder in older *** its prevalence,its pathogenesis remains unclea *** addition to the most widely accepted causes,which in clude excessive amyloid-beta aggregation,tau hyperphosphorylation,and deficiency of the neurotransmitter acetylcholine,numerous studies have shown that the dopaminergic system is also closely associated with the occurrence and development of this *** is a crucial catecholaminergic neurotransmitter in the human ***-associated treatments,such as drugs that target dopamine receptor D and dopamine analogs,can improve cognitive function and alleviate psychiatric symptoms as well as ameliorate other clinical *** r,therapeutics targeting the dopaminergic system are associated with various adverse reactions,such as addiction and exacerbation of cognitive *** review summarizes the role of the dopaminergic system in the pathology of Alzheimer's disease,focusing on currently available dopamine-based therapies for this disorder and the common side effects associated with dopamine-related *** aim of this review is to provide insights into the potential connections between the dopaminergic system and Alzheimer's disease,thus helping to clarify the mechanisms underlying the condition and exploring more effective therapeutic options.

关键词： adverse drug reaction Alzheimer's disease catecholamine dopamine receptor dopamine receptor heterodimers dopaminergic system neurodegenerative disease neurotransmitter signaling pathways traditional Chinese medicine treatment

Brain-derived neurotrophic factor plays with TRiC:focus on synaptic dysfunction in Huntington’s disease

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Neural Regeneration Research 2025年第10期20卷 2919-2920页

作者： Yingli gu Kijung Sung Chengbiao Wu Department of Neurosciences University of California San DiegoLa JollaCAUSA

Brain-derived neurotrophic factor(BDNF)exerts pleiotropic effects on brain processes including psychiatric disorders,aging,neurodegeneration,and metabolic homeostasis.A simple PubMed search using the key word“BDNF,”to date,yields over 33,000 *** fundamental biology to potential therapeutic applications,BDNF has clearly garnered extensive and significant attention in the field of neurobiology research.

关键词： Huntington homeostasis therapeutic

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钢筋混凝土受弯构件斜截面的疲劳计算方法

太原工学院学报 1983年第1期 83-99页

作者：季惠民顾传霖

本文通过21根 T 形梁,在多次重复荷载作用下的试验研究,全面地分析了剪跨比,荷载水平及重复次数等对混凝土抗剪能力的影响,首次提出了考虑混凝土抗剪作用的钢筋混凝土梁斜截面疲劳极限强度的计算方法,及斜裂缝控制等。通过与试验资料的... 详细信息

本文通过21根 T 形梁,在多次重复荷载作用下的试验研究,全面地分析了剪跨比,荷载水平及重复次数等对混凝土抗剪能力的影响,首次提出了考虑混凝土抗剪作用的钢筋混凝土梁斜截面疲劳极限强度的计算方法,及斜裂缝控制等。通过与试验资料的比较,可知它比现行规范(TJ10-74)中的有关计算方法更为合理,且具有明显的经济效果。计算公式概念明确、计算方便,并可制成表格,供设计使用。

关键词：斜截面疲劳强度计算方法力学强度斜裂缝钢筋混凝土受弯构件