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Relationship between radiogenic heat production in granitic rocks and emplacement age

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Energy Geoscience 2023年第4期4卷 108-118页

作者： Dawei liao Dongjun Feng jun Luo Xiaorui Yun Sinopec Petroleum Exploration and Production Research Institute Beijing102206China

Granites play a crucial role in the Earth's thermal regime and its *** heat production(RHP)by the decay of radioactive elements(U,Th,K)in granites is a significant parameter in estimating the thermal structure of the *** variability of granites with their emplacement ages could provide insights for thermal modeling in different geological *** aggregated RHP from 2877 globally-distributed granitic samples of continental crust are analyzed for this study;these sample cover the entire geological *** average bulk RHP in all types of granitic rocks of all ages is 2.92±1.86μW/m^(3).The RHP tends to increase gradually with progressively younger geologic emplacement age,based on a statistical analysis of the ***,the youngest granites do not necessarily have the highest *** mean RHP in 181 representative Cenozoic Himalayan leucogranitesdwhich are the youngest granites found on Earth,is as low as 1.84μW/m^(3).This is probably related to the initial conditions of magma formation,magmatic source material,and differentiation processes in the HimalayaneTibetan *** correcting the decay factor,variations of the RHP in the emplaced granitic rocks are obtained,indicating the changing levels of heat production and different thermal regimes on Earth in various geological *** highest RHP in granitic rocks emplaced in the Archean and Early Proterozoic corresponds to two global-scale collisional events during supercontinent cycles,at 2.7 and 1.9 Ga *** of granites can be an important indicator in the study of Earth's thermal regime and its evolution.

关键词： Radiogenic heat production Emplacement age Himalayan leucogranites Continental crust

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美国儿童阅读推广机制调研及其对我国的启示

大学图书情报学刊 2025年第1期43卷 137-144页

作者：廖颖深圳市南山区图书馆 518000

儿童阅读推广服务不仅是图书馆服务的重点领域,也是其发展的关键环节。文章采用网络调研与文献分析法,系统梳理和分析了美国公共图书馆在儿童阅读推广方面的策略和实践。研究重点包括美国公共图书馆儿童服务的政策框架、实施策略、社会... 详细信息

儿童阅读推广服务不仅是图书馆服务的重点领域,也是其发展的关键环节。文章采用网络调研与文献分析法,系统梳理和分析了美国公共图书馆在儿童阅读推广方面的策略和实践。研究重点包括美国公共图书馆儿童服务的政策框架、实施策略、社会参与、数字化融合、分级阅读推广情况与方式。研究表明,美国通过政策支持、多元化服务模式、紧密的社区与家庭合作、积极适应数字化转型以及注重儿童分级阅读推广等措施,有效满足了儿童的多元化阅读需求,进而提出构建全面的政策框架、深化社区及家庭参与、积极实施分级阅读策略、拥抱数字化转型等建议,以期推动我国儿童阅读推广高质量可持续性发展。

关键词：数字化转型儿童阅读推广实施策略多元化阅读政策框架可持续性发展家庭参与图书馆服务

Structure and mechanics of native and decellularized porcine cranial dura mater

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Engineered Regeneration 2023年第2期4卷 205-213页

作者： Ashma Sharma jun liao Lakiesha N.Williams J.Crayton Pruitt Family Department of Biomedical Engineering University of FloridaGainesvilleFL 32611United States Department of Bioengineering University of Texas at ArlingtonArlingtonTX 76010United States

The dura mater is the outermost layer of meninges and consists of a dense elastic membrane that keeps cere-brospinal fluid inside the *** most cranial surgical interventions,the dura mater is incised and needs to be repaired with a graft *** assessed decellularized porcine dura mater as a novel graft material by quantifying the mechanical and structural properties of the dura *** dura mater was decellular-ized using the Sodium Dodecyl Sulfate(SDS)technique and subjected to uniaxial tensile testing,micro indentation testing,histological analysis,and Transmission Electron Microscopy(TEM).For native dura,we found the tensile modulus in the linear region(15%-25%strain)to be 19.31±1.23 MPa,with an initial tensile modulus(0%-3.5%strain range)of 451±0.30 kPa,and the failure stress as 4.61±1.50 MPa at 35%*** decellularized dura,the tensile modulus in the linear region was 10.81±0.88 MPa,the initial tensile modulus was 226±22 kPa,and the failure stress was 4.55±1.05 MPa at 55%*** effective compressive modulus was 7 to 19 kPa and 19-57 kPa for the native dura and the decellularized dura,*** histological and TEM observations showed that the orientation of fibers within the dura was maintained after *** short,our study demonstrated that decellularized porcine dura was able to maintain its overall morphological/structural integrity and preserve the native dura’s mechanical behavior,which provides a solid foundation for its use as a functional grafting material.

关键词： Cranial dura Decellularization Mechanical properties

Mechanical and Tribological Properties of CrN Coated Inconel X750

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Journal of Wuhan University of Technology(Materials Science) 2019年第4期34卷 804-810页

作者： LIU Jiliang liao Ridong School of Mechanical Engineering Beijing Institute of TechnologyBeijing 100081China Beijing Liang Xin Technology Co. Ltd.Beijing 100081China College of Nuclear Science and Technology Beijing Normal UniversityBeijing 100875China Beijing Radiation Center Beijing 100875China China North Vehicle Research Institute Beijing 100072China

Three CrN coatings were deposited on the Inconel X750 through the metal vapor vacuum arc ion implantation and the magnetic filtered cathodic vacuum arc deposition system(MEVVA-FCVA) with the N2 flow rates of 10,50,and 100sccm, *** surface morphologies and cross-section morphologies of the CrN coatings were obtained through scanning electron microscopy(SEM) and an optical *** microstructures of the coatings were characterized through X-ray diffraction(XRD).The hardness and the elastic modulus of the coatings were tested by a nano-hardness *** adhesion strength and friction coefficients were investigated through scratch tests and ball-on-disk tests and the wear tracks were tested by the optical profilometer. The experimental results indicate that the CrN coating deposited on the Inconel X750 substrate displays a uniform thickness and a smooth surface. The mechanical properties behaves well as the N2 flow rate *** CrN coating significantly reduces the friction coefficient fluctuation and improves the antiadhesion and anti-wear properties of the Inconel X750.

关键词： inconel X750 N2 flow rate CrN coating mechanical properties tribological properties

Parkinson disease drug screening based on the interaction between D2 dopamine receptor and beta-arrestin 2 detected by capillary zone electrophoresis

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Protein & Cell 2011年第11期2卷 899-905页

作者： Zheng Zhou jun-Ming liao Peng Zhang jun-Bao Fan Jie Chen Yi Liang State Key Laboratory of Virology College of Life SciencesWuhan UniversityWuhan 430072China

Parkinson’s disease is the second most common neurodegenerative disease in the ***-arrestin-2 has been reported to be an important protein involved in D2 dopamine receptor desensitization,which is essential to Parkinson’s ***,the potential value of pharmacological inactivation of G protein-coupled receptor kinase or arrestin in the treatment of patients with Parkinson’s disease has recently been *** studied the interaction between D2 dopamine receptor and beta-arrestin-2 and the pharmacological regulation of chemical compounds on such interaction using capillary zone *** results from screening more than 40 compounds revealed three compounds that remarkably inhibit the beta-arrestin-2/D2 dopamine receptor interaction among *** compounds are promising therapies for Parkinson’s disease,and the method used in this study has great potential for application in large-scale drug screening and evaluation.

关键词： drug screening D2 dopamine receptor beta-arrestin-2 capillary zone electrophoresis proteinprotein interaction Parkinson’s disease

Base editor-mediated large-scale screening of functional mutations in bacteria for industrial phenotypes

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Science China(Life Sciences) 2024年第5期67卷 1051-1060页

作者： Yaomeng Yuan Xihao liao Shuang Li Xin-hui Xing Chong Zhang MOE Key Laboratory for Industrial Biocatalysis Institute of Biochemical EngineeringDepartment of Chemical EngineeringTsinghua UniversityBeijing 100084China Institute of Biopharmaceutical and Health Engineering Tsinghua Shenzhen International Graduate SchoolShenzhen 518055China Institute of Biomedical Health Technology and Engineering Shenzhen Bay LaboratoryShenzhen 440300China Center for Synthetic and Systems Biology Tsinghua UniversityBeijing 100084China

Base editing,the targeted introduction of point mutations into cellular DNA,holds promise for improving genome-scale functional genome screening to single-nucleotide *** efforts in prokaryotes,however,remain confined to loss-of-function screens using the premature stop codons-mediated gene inactivation library,which falls far short of fully releasing the potential of base ***,we developed a base editor-mediated functional single nucleotide variant screening pipeline in Escherichia *** constructed a library with 31,123 sgRNAs targeting 462 stress response-related genes in ***,and screened for adaptive mutations under isobutanol and furfural selective *** by the screening results,we successfully identified several known and novel functional *** pipeline might be expanded to the optimization of other phenotypes or the strain engineering in other microorganisms.

关键词： base editor high-throughput large-scale screening Escherichia coli functional mutation

Ethylene sulfite based electrolyte for non-aqueous lithium oxygen batteries

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Chinese Chemical Letters 2016年第9期27卷 1485-1489页

作者： Chaolumen Wu Chen-Bo liao Lei Li jun Yang School of Chemistry and Chemical Engineering Shanghai Key Lab of Electrical Insulation and Thermal AgingShanghai Jiao Tong University Shanghai Electrochemical Energy Devices Research Center School of Chemistry and Chemical EngineeringShanghai jiao Tong University

Non-aqueous lithium-oxygen （Li-O2） batteries have been considered as the superior energy storage system due to their high-energy density, however, some challenges limit the practical application of Li- O2 batteries. One of them is the lack of stable electrolyte. In this communication, a novel electrolyte with ethylene sulfite （ES） used as solvent for Li-O2 batteries was reported. ES solvent showed low volatility and high electrochemical stability. Without a catalyst in the air-electrode of Li-O2 batteries, the batteries showed high specific capacity, good round-trip efficiency and cycling stability.

关键词： Lithium-oxygen batteries Electrolyte Ethylene sulfite Cycling stability Electrochemical stability

Myopia genetics in genome-wide association and postgenome-wide association study era

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International Journal of Ophthalmology(English edition) 2019年第9期12卷 1487-1492页

作者： Xuan liao Qing-Qing Tan Chang-jun Lan Department of Ophthalmology Affiliated Hospital of North Sichuan Medical CollegeDepartment of Ophthalmology and Optometry North Sichuan Medical College

Genome-wide association studies(GWAS) of myopia and refractive error have generated exciting results and identified novel risk-associated loci. However, the interpretation of the findings of GWAS of complex diseases is not straightforward and has remained challenging. This review provides a brief summary of the main focus on the advantages and limitations of GWAS of myopia, with potential strategies that may contribute to further insight into the genetics of myopia in the post-GWAS or omics era.

关键词： myopia genetic variation genome-wide association studies omics

Effectiveness of exploring historical commits for developer recommendation： an empirical study

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Frontiers of Computer Science 2018年第3期12卷 528-544页

作者： Xiaobing SUN hui YANG Hareton LEUNG Bin LI Hanchao (Jerry) LI Lingzhi liao School of Information Engineering Yangzhou University Yangzhou 225127 China Information Technology Research Base of Civil Aviation Administration of China Civil Aviation University of China Tianjin 300300 China Department of Computing The Hong Kong Polytechnic University Hong Kong China Coventry University Coventry CVI 5FB UK State Key Laboratory for Novel Software Technology Nanjing University Nanjing 210093 China Nanjing University of Information Science and Technology Nanjing 210044 China

Developer recommendation is an essential task for resolving incoming issues in the evolution of software. Many developer recommendation techniques have been developed in the literature; among these studies, most techniques usually combined historical commits as supplementary information with bug repositories and/or source-code repositories to recommend developers. However, the question of whether the messages in historical commits are always useful has not yet been answered. This article aims at solving this problem by conducting an empirical study on four open-source projects. The results show that：（1） the number of meaningful words of the commit description has an impact on the quality of the commit, and a larger number of meaningful words in the description means that it can generally better reflect developers＇ expertise; （2） using commit description to recommend the relevant developers is better than that using relevant files that are recorded in historical commits; （3） developers tend to change the relevant files that they have changed many times before; （4） developers generally tend to change the files that they have changed recently.

关键词： developer recommendation historical commits empirical study