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32例川崎病临床分析

心肺血管病杂志 2009年第5期28卷 340-343页

作者：陈晖北京市海淀医院儿科 100080

目的：探讨不同类型川崎病（Kawasaki diseaseKD）临床表现的共同与不同点，及静脉丙种球蛋白（IVIG）的治疗效果。方法：回顾性分析我科1993年3月至2009年5月，32例住院的KD患儿（3个月～11岁）的临床资料。结果：不典型（不完全）比... 详细信息

目的：探讨不同类型川崎病（Kawasaki diseaseKD）临床表现的共同与不同点，及静脉丙种球蛋白（IVIG）的治疗效果。方法：回顾性分析我科1993年3月至2009年5月，32例住院的KD患儿（3个月～11岁）的临床资料。结果：不典型（不完全）比典型的KD临床表现要少，但其临床炎症指标[血沉（ESR）、反应蛋白（cRP）和白细胞（wBc）]显著增高有一致性。KD的心血管损害除冠状动脉病变（cAL）外，还可累及心包、心肌及心内膜。心外表现有关节炎、黄疸、肝脏肿大及胆囊积液，婴幼儿可有惊厥、易激惹及腹泻等。KD对IVIG治疗敏感。对IVIG疗效不佳（IVIG抵抗）者，炎症指标明显增高，cAL重。结论：凡具有短期高热、KD面容、ESR、cRP及wBc明显增高，要警惕KD。对典型与不典型KD，IVIG均有良好的疗效；对IVIG疗效不佳者，推荐2g／kg2次给药。

关键词：川崎病冠状动脉疾病丙种球蛋白炎症指标

Enhancing survival, engraftment, and osteogenic potential of mesenchymal stem cells

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world Journal of Stem cells 2019年第10期11卷 748-763页

作者： Daniel García-Sánchez Darío Fernández Joséc Rodríguez-Rey Flor M Pérez-campo Department of Molecular Biology Faculty of MedicineUniversity of CantabriaCantabria 39011Spain Laboratorio de Biología celular y Molecular Facultad de OdontologíaUniversidad Nacional del NordesteCorrientes W3400Argentina consejo Nacional de Investigaciones científicas y Técnicas Ciudad de CorrientesCorrientes W3400Argentina

Mesenchymal stem cells(MScs)are promising candidates for bone regeneration therapies due to their plasticity and easiness of ***-based treatments are generally considered a safe procedure,however,the long-term results obtained up to now are far from *** main causes of these therapeutic limitations are inefficient homing,engraftment,and osteogenic *** studies have proposed modifications to improve MSc engraftment and osteogenic differentiation of the transplanted *** strategies are aimed to improve cell resistance to the hostile microenvironment found in the recipient tissue and increase cell survival after *** strategies could range from a simple modification of the culture conditions,known as cell-preconditioning,to the genetic modification of the cells to avoid cellular *** efforts have also been done in order to enhance the osteogenic potential of the transplanted cells and induce bone formation,mainly by the use of bioactive or biomimetic scaffolds,although alternative approaches will also be *** review aims to summarize several of the most recent approaches,providing an up-to-date view of the main developments in MScbased regenerative techniques.

关键词： Mesenchymal stem cells Bone regeneration Hypoxia Anoikis Preconditioning Bioactive scaffolds Senescence Engraftment Homing Osteogenesis

Leishmaniasis in the Argentine Republic: Temporal and geographical distribution from 2013 to 2017

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Asian Pacific Journal of Tropical Medicine 2019年第7期12卷 300-305页

作者： GermanóMaría J Salomón María c Neira Gisela Lozano Esteban Mackern-Oberti Juan P cargnelutti Diego E consejo Nacional de Investigaciones científicas y Técnicas Centro Científico y Tecnológico de MendozaInstituto de Medicina y Biología Experimental de CuyoMendozaArgentina Universidad Nacional de cuyo Facultad de Ciencias Médicasárea de ParasitologíaMendozaArgentina Universidad Juan Agustín Maza Facultad de Ciencias Veterinarias y AmbientalesCentro de Investigación en Parasitología RegionalMendozaArgentina Universidad Nacional de cuyo Facultad de Ciencias MédicasInstituto de FisiologíaMendozaArgentina

Objective: To assess the temporal and geographical distribution of confirmed cases of cutaneous, mucocutaneous and visceral leishmaniasis in the Argentine Republic from 2013 to 2017. Methods: A retrospective study was carried out using data collected from the Integrated Surveillance Bulletin database of the National System of Health Surveillance. confirmed cases of cutaneous, mucocutaneous and visceral leishmaniasis up to the 52 nd epidemiological week of each year was included. Results: In the 5 years period, 1 295 confirmed leishmaniasis cases were reported in the Argentine Republic. One thousand twenty-eight(1 028) cases corresponded to cutaneous leishmaniasis(87.10%), being the most common type of leishmaniasis. Mucocutaneous leishmaniasis was in the second place in the country with 115 cases reported, mostly in the Northwest and Northeast regions. A total of 52 individuals with visceral leishmaniasis were identified and Misiones Province was the most affected. conclusions: It is important to analyze the temporal and geographical distribution of leishmaniasis in order to provide an adequate management and surveillance.

关键词： Leishmaniasis Epidemiology Argentine Republic Temporal distribution Geographical distribution

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含孔橡胶矩形板的单向压缩

哈尔滨工程大学学报 2008年第5期29卷 460-464页

作者：王勇唐立强吴国辉哈尔滨工程大学建筑工程学院黑龙江哈尔滨150001

在船舶和海洋工程领域,以橡胶材料为代表的超弹性材料应用越来越广泛,故研究橡胶材料的损伤和破坏的力学机理是一个非常现实的重大课题.该文力求通过研究橡胶材料的空穴萌生和增长来了解超弹性材料的损伤和破坏的力学机理.利用高玉臣给... 详细信息

在船舶和海洋工程领域,以橡胶材料为代表的超弹性材料应用越来越广泛,故研究橡胶材料的损伤和破坏的力学机理是一个非常现实的重大课题.该文力求通过研究橡胶材料的空穴萌生和增长来了解超弹性材料的损伤和破坏的力学机理.利用高玉臣给出的一类应变能函数分析了含单个微孔橡胶矩形板在受单向压缩作用下生长的有限变形问题.利用不可压缩条件确定了矩形板的变形模式,此变形模式含有2个物理意义完全不一样的参数,其中一个参数可由远场的变形状态确定,另一个参数可用最小势能原理导出变分近似解.进而给出了反映微孔变形的参数与外载间的关系,以及孔边应力分布的解析解.结果显示,高玉臣给出的应变能函数能较好地描述橡胶材料的有限变形特性,含有单个圆柱微孔的三维橡胶矩形板受压与受拉时的力学特性相差较大.

关键词：橡胶矩形板有限变形超弹性应变能函数微孔变形

Magnetocaloric effect in ErNi2 melt-spun ribbons

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Journal of Rare Earths 2020年第6期38卷 612-616页

作者： J.L.Sanchez Llamazares P.Ibarra-Gaytan c.F.Sanchez-Valdes D.Rlos-Jara P.Alvarez-Alonso Instituto Potosino de Investigacion ciendfica y Tecnoldgica A.c. Camino a la Presa San Jose 2055Col.Lomas 4San Luis Potosi.S.LP.78216Mexico cPM-TIP University Pavol Jozef SafarikPark Angelinum 9.04154 KosiceSlovakia Division Multidisciplinaria Ciudad UniversitariaUniversidad Aurdnoma de Ciudad Juarez(UACJ)Calle Jose de Jesus Macias Delgado#18100Ciudad Juarez 32579Chihuahua.Mexico Departamento de Fisica Universidad de OviedoCalvo Sotelo s/n33007 OviedoSpain

ErNi2 ribbons were produced by rapid solidification using the melt spinning *** structural,magnetic and magnetocaloric properties in the as-solidified state were studied by X-ray diffraction,scanning electron microscopy,magnetization and specific heat *** are single phase with the Mgcu2-type crystal structure,a curie temperature Tc of 6.8 K and a saturation magnetization at2 K and 5 T of 124.0 A·m2/*** a magnetic field change μ0△H of 5 T(2 T) ribbons show a maximum magnetic entropy change |△SMpeak| of 24.1(16.9) J/(kg·K),and an adiabatic temperature change △Tadmax of8.1(4.4) K;this is similar to the previously reported literature for bulk alloys that were processed through conventional melting techniques followed by prolonged thermal *** addition,the samples also show slightly wider △SM(T) curves with respect to bulk alloys leading to a larger refrigerant capacity.

关键词： ErNi2 Laves phase Melt-spun ribbons Magnetic entropy change Adiabatic temperature change Rare Earths

没食子酸对恩诺沙星在鲤体内的药代动力学及残留的影响研究

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大连海洋大学学报 2016年第6期31卷 658-662页

作者：李改娟刘艳辉陈伟强祖岫杰戴欣赵全东杨炳坤吉林省水产科学研究院吉林长春130033 松辽流域水资源保护局吉林长春130021

为研究没食子酸与恩诺沙星联合用药及单用恩诺沙星在福瑞鲤cyprinus carpio体内的药代动力学参数及其残留消除规律,采用平行对照试验,将体质量为（200±30）g的鲤随机分为单用恩诺沙星组（对照）和联合用药组（没食子酸与恩诺沙星质量比... 详细信息

为研究没食子酸与恩诺沙星联合用药及单用恩诺沙星在福瑞鲤cyprinus carpio体内的药代动力学参数及其残留消除规律,采用平行对照试验,将体质量为（200±30）g的鲤随机分为单用恩诺沙星组（对照）和联合用药组（没食子酸与恩诺沙星质量比为10颐1）,试验水温为26℃,各组均按2 mg/kg（体质量）剂量的恩诺沙星单次混饲口灌给药,于给药后不同时间点采集鲤血浆、肌肉、肝胰脏、肾脏组织,采用高效液相色谱法测定各组织中恩诺沙星的浓度,并使用DAS 3.0药物代谢动力学软件的非房室模型统计矩方法分析药时数据。结果表明,没食子酸能显著增大鲤各组织对恩诺沙星的吸收效率,提高有效药物浓度20.0%~44.9%,并加快了恩诺沙星的代谢和消除,240 h时联合用药组鲤血浆、肌肉组织中药物残留量比对照组分别降低了44.2%和34.1%。

关键词：鲤恩诺沙星没食子酸联合用药药代动力学残留

皮肤微生物菌群在多环芳烃暴露下形成具有不同代谢功能的皮肤型

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中华皮肤科杂志 2024年第12期57卷 1161-1162页

作者： Leung, Marcus H. y. Tong, Xinzhao Shen, Zhiyong Du, Shicong Bastien, Philippe Appenzeller, Brice M. R. Betts, Richard J. Mezzache, Sakina Bourokba, Nasrine cavusoglu, Nukhet Aguilar, Luc Misra, Namita clavaud, cécile Lee, Patrick K. H. School of Energy and Environment City University of Hong Kong Hong Kong SAR China Department of Biological Sciences School of Science Xi’an Jiaotong-Liverpool University Suzhou China L’Oréal Research and Innovation Aulnay-Sous-Bois France Human Biomonitoring Research Unit Luxembourg Institute of Health Strassen Luxembourg L’Oréal Research and Innovation Pudong China

随着宏基因组测序和微生物代谢物质谱分析技术的发展,对于皮肤微生态的认识不断深入。研究显示,人体皮肤中存在独特的微生物亚群,又称为皮肤型(cutotype),不同的皮肤型在微生物多样性、组成、功能和耐药性等方面存在差异。深入研究个体... 详细信息

随着宏基因组测序和微生物代谢物质谱分析技术的发展,对于皮肤微生态的认识不断深入。研究显示,人体皮肤中存在独特的微生物亚群,又称为皮肤型(cutotype),不同的皮肤型在微生物多样性、组成、功能和耐药性等方面存在差异。深入研究个体皮肤型的分布特征及其影响因素有助于识别皮肤疾病相关的皮肤型标志物,从而开发个性化的皮肤健康管理方案。

关键词：质谱分析技术皮肤型皮肤疾病微生物菌群代谢功能宏基因组测序人体皮肤多环芳烃

Interaction studies between rice and Pyricularia grisea in Jilin province,***

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Interaction studies between rice and Pyricularia grisea in J...

Ga1-xMnxN Grown by Low Pressure Metalorganic chemical Vapor Deposition and application in polarized LED

第十一届全国植物基因组学大会

作者： J.c.wang~(1*),y.L.Li~2,J.w.wen~1,L.J.Meng~2,w.P.Liu~1,y.M.Jia~2,S.R.yan~1,J.c.Pang~1,J.Q.wang~3,J. P.Ren~1 1 Institute of Plant Protection,Jilin Academy of Agricultural Sciences,changchun city,130124,Jilin Pro.,P.R. china. 2 Tonghua Academy of Agricultural Sciences Research,Meihekou city,Jilin Province,135007,P.R.china. 3 Station of Agricultural Technology Extention of yanhe Town,yushu city,Jilin Province,130421,P.R.china

Jilin Province is an important Japonica-type rice producing areas in Northeast china,and rice blast caused by Pyricularia grisea,is a serious disease in local *** the molecular biotechnology and conventional agricultu...

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Ga1-xMnxN Grown by Low Pressure Metalorganic Chemical Vapor ...