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Surgical treatment of pelvic fracture urethral distraction defects in boys:which approach is suitable?

Asian Journal of Andrology 2020年第3期22卷 292-295页

作者： Lin Wang Hai-Lin Guo hui-quan shu Jie Gu Chong-Rui Jin Fang Chen Ying-Long Sa Department of Urology Shanghai Jiao Tong University Affiliated Sixth People's HospitalShanghai 200233China Department of Urology Shanghai Children's HospitalShanghai Jiao Tong UniversityShanghai 200062China Shanghai Eastern Institute of Urologic Reconstruction Shanghai 200233China

Pelvic fracture urethral distraction defects(PFUDDs)are relatively infrequent in boys,and treatment for PFUDDs presents one of the most difficult problems in urological *** urethroplasty is considered an ideal surgical procedure for PFUDDs in ***,various surgical approaches for anastomotic urethroplasty have been proposed,including a simple transperineal approach,a tran sperineal in tercorporal septal separati on approach,a tran sperineal in ferior pubic approach,and a combined transpubic・perineal *** study aims to determine which surgical approach is best for PFUDDs in *** retrospectively identified 22 boys with PFUDDs aged 2-14 years who underwent anastomotic urethroplasty via different approaches between January 2008 and December ***-up was performed in all the 22 patients for 6-123(mean:52.0)***,20 of the 22 boys(90.9%)were successfully treated,including 1 of 2 patients treated with a simple transperineal approach,3 of 3 with a transperineal approach with intercorporal septal separation,14 of 15 with a transperineal inferior pubic approach,and 2 of 2 with a combined transpubic-perineal *** patients had failed outcomes after the operation,and stenosis *** on the outcome of the 22 patients,we can draw a preliminary conclusion that most boys(20/22)can be treated with a transperineal inferior pubic approach or simpler procedures without the need of completely removing or incising the *** combined transpubic-perineal approach can be used in cases of extremely long urethral distract defects.

关键词： children pelvic fracture posttraumatic urethra urethral stenosis

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Measurement of acceleration and angular velocity of particles during a 3D silo discharge

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Particuology 2024年第9期92卷 61-71页

作者： Tongtong Mu Yiming Li quan Chen Ran Li hui Yang College of Medical Instrument Shanghai University of Medicine and Health SciencesShanghai201318China School of Optical-Electrical and Computer Engineering University of Shanghai for Science and TechnologyShanghai200093China

Accurate measurement of the three-dimensional(3D)movement of discrete particles is crucial for comprehending complex granular rheology in *** this paper,the acceleration and angular velocity of particles in 3D silos are measured by using a spherical detector based on inertial technology and magnetic positioning *** acceleration of particles is the largest in the center of silos,which suggest that the resistance generated by friction and extrusion is the ***,the angular velocity distribution follows lognormal function except for particles near the *** correlation between acceleration and angular velocity is opposite in different flow *** reveals for the first time that the extent to which the resultant force on the particles affects their rotational motion is related to the flow *** results have practical significance for regulating the granular flow pattern and optimizing the structural design of silos.

关键词： Granularflow Silo Angular velocity Acceleration

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Sliced Average Variance Estimation for Tensor Data

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Acta Mathematicae Applicatae Sinica 2024年第3期40卷 630-655页

作者： Chuan-quan LI Pei-wen XIAO Chao YING Xiao-hui LIU School of Statistics Jiangxi University of Finance and EconomicsNanchang 330013China Key Laboratory of Data Science in Finance and Economics Jiangxi University of Finance and EconomicsNanchang 330013China Biostatistics and Medical Informatics University of Wisconsin MadisonMadison 53726USA

Tensor data have been widely used in many fields,e.g.,modern biomedical imaging,chemometrics,and economics,but often suffer from some common issues as in high dimensional *** to find their low-dimensional latent structure has been of great interest for *** this end,we develop two efficient tensor sufficient dimension reduction methods based on the sliced average variance estimation(SAVE)to estimate the corresponding dimension reduction *** first one,entitled tensor sliced average variance estimation(TSAVE),works well when the response is discrete or takes finite values,but is not■consistent for continuous response;the second one,named bias-correction tensor sliced average variance estimation(CTSAVE),is a de-biased version of the TSAVE *** asymptotic properties of both methods are derived under mild *** and real data examples are also provided to show the superiority of the efficiency of the developed methods.

关键词： tensor data sliced average variance estimation sufficient dimension reduction central subspace

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Enhancing personalized exercise recommendation with student and exercise portraits

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Journal of Electronic Science and Technology 2024年第2期22卷 91-109页

作者： Wei-Wei Gao hui-Fang Ma Yan Zhao Jing Wang quan-Hong Tian College of Computer Science and Engineering Northwest Normal UniversityLanzhou730070China Computer Center of Gansu Province Lanzhou730070China

The exercise recommendation system is emerging as a promising application in online learning scenarios,providing personalized recommendations to assist students with explicit learning *** solutions generally follow a collaborative filtering paradigm,while the implicit connections between students(exercises)have been largely *** this study,we aim to propose an exercise recommendation paradigm that can reveal the latent connections between student-student(exercise-exercise).Specifically,a new framework was proposed,namely personalized exercise recommendation with student and exercise portraits(PERP).It consists of three sequential and interdependent modules:Collaborative student exercise graph(CSEG)construction,joint random walk,and recommendation list ***,CSEG is created as a unified heterogeneous graph with students’response behaviors and student(exercise)***,a joint random walk to take full advantage of the spectral properties of nearly uncoupled Markov chains is performed on CSEG,which allows for full exploration of both similar exercises that students have finished and connections between students(exercises)with similar ***,we propose to optimize the recommendation list to obtain different exercise *** analyses of two public datasets,the results demonstrated that PERP can satisfy novelty,accuracy,and diversity.

关键词： Educational data mining Exercise recommend Joint random walk Nearly uncoupled Markov chains Optimization Personalized learning

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Jianpi Gushen Huayu decoction ameliorated diabetic nephropathy through modulating metabolites in kidney,and inhibiting TLR4/NF-κB/NLRP3 and JNK/P38 pathways

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World Journal of Diabetes 2024年第3期15卷 502-518页

作者： Zi-Ang Ma Li-Xin Wang hui Zhang Han-Zhou Li Li Dong Qing-Hai Wang Yuan-Song Wang Bao-ChaoPan shu-Fang Zhang Huan-Tian Cui shu-quan Lv Graduate School Hebei University of Chinese MedicineShijiazhuang 050000Hebei ProvinceChina Department of Endocrinology Cangzhou Hospital of Integrated Traditional Chinese Medicine and Western Medicine of Hebei Province Affiliated to Hebei University of Chinese MedicineCangzhou 061000Hebei ProvinceChina School of Integrative Medicine Tianjin University of Traditional Chinese MedicineTianjin 300000China The First School of Clinical Medicine Yunnan University of Traditional Chinese MedicineKunming 065000Yunnan ProvinceChina Department of Endocrinology Hebei Cangzhou Hospital of Integrative MedicineCangzhou 061000Hebei ProvinceChina

BACKGROUND Jianpi Gushen Huayu Decoction(JPGS)has been used to clinically treat diabetic nephropathy(DN)for many ***,the protective mechanism of JPGS in treating DN remains *** To evaluate the therapeutic effects and the possible mechanism of JPGS on *** We first evaluated the therapeutic potential of JPGS on a DN mouse *** then investigated the effect of JPGS on the renal metabolite levels of DN mice using non-targeted ***,we examined the effects of JPGS on c-Jun N-terminal kinase(JNK)/P38-mediated apoptosis and the inflammatory responses mediated by toll-like receptor 4(TLR4)/nuclear factor-kappa B(NF-κB)/NOD-like receptor family pyrin domain containing 3(NLRP3).RESULTS The ameliorative effects of JPGS on DN mice included the alleviation of renal injury and the control of inflammation and oxidative *** metabolomic analysis revealed that JPGS altered the metabolites of the kidneys in DN mice.A total of 51 differential metabolites were *** analysis results indicated that nine pathways significantly changed between the control and model groups,while six pathways significantly altered between the model and JPGS *** related to cysteine and methionine metabolism;alanine,tryptophan metabolism;aspartate and glutamate metabolism;and riboflavin metabolism were identified as the key pathways through which JPGS affects *** experimental validation showed that JPGS treatment reduced the expression of TLR4/NF-κB/NLRP3 pathways and JNK/P38 pathway-mediated apoptosis related *** JPGS could markedly treat mice with streptozotocin(STZ)-induced DN,which is possibly related to the regulation of several metabolic pathways found in ***,JPGS could improve kidney inflammatory responses and ameliorate kidney injuries in DN mice via the TLR4/NF-κB/NLRP3 pathway and inhibit JNK/P38 pathwaymediated apoptosis in DN mice.

关键词： Diabetic nephropathy Jianpi Gushen Huayu Decoction Oxidative stress Inflammation Untargeted metabolomics Toll-like receptor 4/nuclear factor-kappa B/NOD-like receptor family pyrin domain containing 3 pathway c-Jun N-terminal kinase/P38-mediated apoptosis

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The BTB/TAZ domain-containing protein CmBT1-mediated CmANR1 ubiquitination negatively regulates root development in chrysanthemum

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Journal of Integrative Plant Biology 2024年第2期66卷 285-299页

作者： Lian-Da Du Zhang-Ji Guan Yan-Hong Liu hui-Dong Zhu quan Sun Da-Gang Hu Cui-hui Sun Shandong Collaborative Innovation Center of Fruit&Vegetable Quality and Efficient Production College of Horticulture Science and EngineeringShandong Agricultural UniversityTaian 271018China

Roots are fundamental for plants to adapt to variable environmental *** development of a robust root system is orchestrated by numerous genetic determinants and,among them,the MADS-box gene ANR1 has garnered substantial *** research has demonstrated that,in chrysanthemum,CmANR1positively regulates root system ***,the upstream regulators involved in the CmANR1-mediated regulation of root development remain *** this study,we successfully identified bric-a-brac,tramtrack and broad(BTB)and transcription adapter putative zinc finger(TAZ)domain protein CmBT1 as the interacting partner of CmANR1 through a yeasttwo-hybrid(Y2H)screening ***,we validated this physical interaction through bimolecular fluorescence complementation and pull-down *** assays revealed that CmBT1 exerted a negative influence on root development in *** both in vitro and in vivo assays,it was evident that CmBT1mediated the ubiquitination of CmANR1 through the ubiquitin/26S proteasome *** ubiquitination subsequently led to the degradation of the CmANR1 protein and a reduction in the transcription of CmANR1-targeted gene CmPIN2,which was crucial for root development in *** analysis suggested that CmBT1 modulated root development,at least in part,by regulating the level of CmANR1 ***,these findings shed new light on the regulatory role of CmBT1 in degrading CmANR1 through ubiquitination,thereby repressing the expression of its targeted gene and inhibiting root development in chrysanthemum.

关键词： chrysanthemum MADS-box transcription factor root development

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Constructing energetic covalent organic frameworks with high stability and low sensitivity

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Chinese Chemical Letters 2024年第3期35卷 544-548页

作者： hui-Min Guo Xiao-Yu Dong Shan Wang Qian-You Wang shuang-quan Zang Henan Key Laboratory of Crystalline Molecular Functional Materials Green Catalysis Centerand College of ChemistryZhengzhou UniversityZhengzhou 450001China

Developing new functional explosives that display high stability,good energy performance,and low sensitivity are one of the key directions of energetic materials *** this work,two-dimensional(2D)Schiff-based energetic covalent organic frameworks(COFs)are prepared based on triaminoguanidine salts with different anions as building *** from the robust covalent bond in 2D extended polygons and strongπ-πinteractions in the eclipsed interlayers,the synthesized energetic COFs showed higher thermal stability and lower mechanical sensitivity than their precursor *** importantly,incorporating triaminoguanidine salts into COFs effectively increase the corrosion resistance to metal under high humidity conditions,which is due to the imine moieties in COFs functioning asπacceptors and offering strong bonding with metallic *** work provides a new pathway for the development of high-performance energetic materials.

关键词： Covalent organic frameworks Energetic materials High thermal stability Low sensitivity Corrosion resistance

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Single self-leading suture technique for iridodialysis repairment

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International Journal of Ophthalmology(English edition) 2024年第9期17卷 1752-1754页

作者： Jing-Wen hui quan-Hong Han Yong Tang Ying Wang Tianjin Eye Hospital Tianjin 300020China Tianjin Key Lab of Ophthalmology and Visual Science Tianjin 300020China Clinical College of Ophthalmology Tianjin Medical UniversityTianjin 300020China

Dear Editor,We described an innovative“single self-leading suture technique”for repairing *** of moving the needle forth and back,our method is easier to manipulate in the narrow surgical space between the cornea and lens,which will decrease the unnecessary complications related to iatrogenic *** provide an economical friendly and less time-taking method,which improves the suture accuracy.

关键词： dialysis needle suture

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Sea-level change in coastal areas of China:Status in 2021

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Advances in Climate Change Research 2024年第3期15卷 515-524页

作者： Wen-Shan LI hui WANG Wen-Xi XIANG Ai-Mei WANG Wei-Qing XU Yu-Xi JIANG Xin-hui WU Meng-Yuan quan National Marine Data and Information Service Tianjin 300171China Ocean University of Chin1 Qingdao 266100China University of Michigan‒Shanghai Jiao Tong University Joint Institute Shanghai 200030China

The sea level in coastal areas of China reached the second highest in 2021,just after that recorded in *** force and dynamic analyses based on tide gauges,satellite observations,reanalysis data and regional numerical outputs were conducted to understand these abnormally high sea levels and determine their possible *** show that the coastal sea level of China had increased at an annual rate of 3.4±0.3 mm during 1980-2021,with an acceleration of 0.06±0.02 mm per *** superposition of significant oscillations of quasi-2,3-7,quasi-9,quasi-11,quasi-19 and 20-30 years contributed to the anomalously high sea *** negative-phased El Nino/Southern Oscillation was correlated with the anomalously high sea level and the north-south anti-phase pattern of the coastal sea level in ***,phase lags of 1-4 months occurred with the sea-level *** a decadal timescale,the Pacific Decadal Oscillation(PDO)was negatively correlated with the anomalous mean sea level(MSL),and the negative-phased PDO contributed to the anomalous sea-level change in ***,the monthly MSL peaked in April and July,and the contribution of wind stress to the anomalously high sea level was 38.5%in the south of the Taiwan Strait in April and 30%along the coast of China in *** results were consistent with the tide gauge and satellite *** agreement was also observed between the coastal sea-level fingerprint and the air and sea surface temperatures.

关键词： Sealevel La Nina PDO Wind stress

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Heat transfer and flow structure in centrally-confined 2-D Rayleigh-Bénard convection

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JOURNAL OF HYDRODYNAMICS 2024年第4期36卷 772-780页

作者： Sun, Cong Wu, Jian-zhao Meng, Xiao-hui Liu, Cai-xi Xu, Wei Dong, Yu-hong Zhou, quan Shanghai Univ Shanghai Key Lab Mech Energy Engn Shanghai Inst Appl Math & Mech Sch Mech & Engn Sci Shanghai 200072 Peoples R China Sci & Technol Res Inst Co Ltd China Elect Equipment Grp Shanghai 200040 Peoples R China

Through direct numerical simulations, we investigated the flow structure and heat transfer of the centrally confined 2-D Rayleigh-B & eacute;nard (RB) convection over the Rayleigh number range 9 x 105 <= Ra <= 109 at a fixed Prandtl number Pr = 4.3. It is found that with increasing Ra, the number of convection rolls in the central vertical channel increases from zero to three. When there is no rolls in the vertical channel, the convective flow in central region is significantly influenced by the boundary layer, whereas when the convection rolls is generated in the vertical channel, the convective flows in central regions is free from the boundary layer limitation, and by defining the characteristic length, one obtains the heat transfer scaling law relation in vertical channel, i.e., Nuvc similar to Ravc0.476 +/- 0.005, which could be the evidence of "ultimate regime".

关键词： Rayleigh-B & eacute nard (RB) turbulence heat transport vertical channel ultimate regime

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