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Science China(Technological Sciences) 2021年第3期64卷 641-650页

作者： SHI Shun WANG JiaYu WANG TianRan ren hui ZHOU YuHao LI Gao HE ChaoLiang CHEN XueSi CAS Key Laboratory of Polymer Ecomaterials Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China College of Applied Chemistry and Engineering University of Science and Technology of ChinaHefei 230026China Jilin Biomedical Polymers Engineering Laboratory Changchun 130022China

Glycopolypeptides as analogs of glycoproteins or glycosaminoglycans represent attractive building blocks for the construction of biomimetic ***,the effects of amino acid chirality on the conformation and enzymatic degradation of glycopolypeptides are often ***,we synthesized and characterized a range of glycopolypeptides composed of galactosylated poly(γ-propargylglutamate)s containing L-and/or D-glutamate *** containing pure Lglutamate residues were predominantlyα-helical,and the helicity increased over the degree of polymerization of the polypeptide backbones(24 to 44).The glycopolypeptide with pure D-glutamate residues adopted a mirroredα-helical conformation,whilst apparent random coil conformation was observed for the glycopolypeptide with equally mixed enantiomeric *** enzymatic degradation rates of the glycopolypeptides were markedly reduced following the introduction of D-glutamate residues into *** pendants on these glycopolypeptides maintained their binding to peanut *** structureproperty relationships provide new insight for the design of biomimetic biomaterials containing glycopolypeptides.

关键词： glycopolypeptides secondary structures enzymatic degradation chirality lectin binding

Effect of Ce on solute redistribution in liquid ahead of solid–liquid interface during solidification of Fe–4 wt.%Si alloy

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Journal of Iron and Steel Research International 2021年第10期28卷 1251-1258页

作者： Yun-ping Ji Ming-xing Zhang Yuan Hou Tong-xin Zhao Yi-ming Li hui-ping ren School of Material and Metallurgy Inner Mongolia University of Science and TechnologyBaotou014010Inner MongoliaChina Inner Mongolia Autonomous Region Key Laboratory of Advanced Metal Materials Baotou014010Inner MongoliaChina School of Mechanical and Mining Engineering The University of QueenslandBrisbaneQLD4072Australia Testing Center Inner Mongolia University of Science and TechnologyBaotou014010Inner MongoliaChina Analytical Applications Center SHIMADZU(China)Co. Ltd.Shanghai200233China

The high efficiency of Ce addition in grain refinement ofδ-ferrite in a cast Fe–4 wt.%Si alloy was *** order to further understand the solute effect of Ce on the grain refinement of δ-ferrite,the conventional directional solidification technique,which enabled to freeze the solid–liquid interface to room temperature,was used to investigate the interfacial morphology and solute redistribution in the liquid at the front of the interface,together with thermodynamic calculation of the equilibrium partition coefficients of Ce and Si in Fe–4 wt.%Si–Ce system using the Equilib module and the FsStel database in FactSage software *** examination using a laser scanning confocal microscope showed a transition of the solid–liquid interface from planar to cellular in the Fe–4 wt.%Si alloy after adding 0.0260 wt.%Ce during the directional solidification ***,electron probe microanalysis revealed an enhanced segregation of Si solute in the liquid at the front of the solid–liquid interface due to the Ce *** solute segregation is considered as the cause of planar to cellular interface transition,which resulted from the creation of constitutional supercooling *** calculation indicated that Ce also segregated at the solid–liquid interface and the Ce addition had negligible effect on the equilibrium partition coefficient of *** is reasonable to consider that the contribution of Ce to the grain refinement ofδ-ferrite in the cast Fe–4 wt.%Si alloy as a solute was marginal.

关键词： Ce Fe-4 wt.%Si alloy Solute redistribution Directional solidification Electron probe microanalysis Thermodynamic calculation

Porphyrin-based Nanosonosensitizers Combined with Targeting Peptides for Sonodynamic Therapy of Glioma

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Chinese Journal of Polymer Science 2022年第9期40卷 1120-1128页

作者： Mei-Yu Jiang Jia-Sheng Wu Wei-Min Liu Hao-hui ren Xin Wang Peng-Fei Wang Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices Technical Institute of Physics and ChemistryChinese Academy of SciencesBeijing 100190China School of Future Technology University of Chinese Academy of SciencesBeijing 100049China

Traditional cancer treatments have disadvantages of large trauma area and toxic side effects while killing cancer ***-targeted sonodynamic therapy(SDT)can effectively improve specificity of cancer treatment and overcome the problem of low tissue penetration depth caused by a photo-driven ***,we developed a porphyrin-based sonosensitizer with a water-soluble polymer as a biological carrier and a cRGD peptide for tumor targeting,which constituted a nano sonosensitizer(T-cRGD NPs)for fluorescence imaging-guided sonodynamic therapy.A comparable sonosensitizer(T-PEG NPs)without the targeting unit was also prepared for illustration of therapeutic *** to the role of peptide targeting,T-cRGD NPs can accumulate and enter tumor cells for fluorescence imaging and show a superior SDT effect than T-PEG NPs in *** imaging in vivo reveals that T-cRGD NPs can enrich in tumor tissues within 14 h with a good biocompatibility.

关键词： Sonodynamic therapy Glioma Cyclic peptide Target enrichment Deep penetration

The electrochemical hydrogen storage performances of Si-added La–Mg–Ni–Co-based A_2B_7-type electrode alloys

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Rare Metals 2015年第8期34卷 569-579页

作者： Yang-Huan Zhang Li-Cui Chen Tai Yang Chao Xu hui-Ping ren Dong-Liang Zhao Key Laboratory of Integrated Exploitation of Baiyun Obo MultiMetal Resources Inner Mongolia University of Science and Technology Department of Functional Material Research Central Iron and Steel Research Institute

In order to improve the electrochemical cycle stability of the RE–Mg–Ni-based A2B7-type electrode alloys, a small amount of Si has been added into the *** casting and annealing technologies were adopted to fabricate the La0.8Mg0.2Ni3.3Co0.2Six(x = 0–0.2) electrode alloys. The impacts of the addition of Si and annealing treatment on the structures and electrochemical performances of the alloys were investigated systematically. The results obtained by XRD and SEM show that all the as-cast and annealed alloys are of a multiphase structure, involving two main phases(La, Mg)2Ni7and La Ni5 as well as a residual phase La Ni3. Both adding Si and the annealing treatment lead to an evident change in the phase abundance and cell parameters of(La, Mg)2Ni7and La Ni5 major phases of the alloy without altering its main phase component. Moreover, the annealing treatment has the composition of the alloy distributed more homogeneously overall and simultaneously causes the grain of the alloy to be coarsened obviously. The electrochemical measurements indicate that adding Si and the annealing treatment give a significant rise to the influence on the electrochemical performances of the alloys. In brief, the cycle stability of the as-cast and annealed alloys evidently increases with the rising of Si content, while their discharge capacities obviously decrease under the same circumstances. Furthermore, the electrochemical kineticproperties of the electrode alloys, including the high rate discharge ability, the limiting current density(IL), hydrogen diffusion coefficient(D), and the charge-transfer resistance, first augment and then decline with the rising of Si content. Similarly, it is found that the above-mentioned electrochemical properties first mount up and then go down with the rising annealing temperature.

关键词： A2B7-type electrode alloy Adding Si Annealing trea

S-type anion channel SLAC1's homologues inhibit inward potassium channels AKT2 and KAT2 in Arabidopsis

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Science Bulletin 2017年第7期62卷 464-466页

作者： Fen-Yong Yao Guo-Ning Qi hui-Min ren An Zhang Jamshaid Hussain Yong-Fei Wang National Key Laboratory of Plant Molecular Genetics Institute of Plant Physiology and Ecology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Shanghai 200032 China University of Chinese Academy of Sciences Shanghai 200032 China Biotechnology Program Department of Environmental Sciences COMSATS Institute of Information Technology Abbottabad 22060 Pakistan

Cations and anions are involved in plant growth,development and signaling responses as essential nutrients,signaling molecules and osmotic components,and the dynamic movement of the diverse ions through biological mem... 详细信息

关键词： SLAC type

Performance analysis of two RDSS positioning modes of BeiDou-3 system

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Astrodynamics 2022年第3期6卷 317-327页

作者： Dongxia Wang Rui Guo Nan Xing Zhijun Liu Tianqiao Zhang hui ren Xiaojie Li Aerospace Information Research Institute Chinese Academy of SciencesBeijing 100094China Operation Control Department Beijing Satellite Navigation CenterBeijing 100094China Astronomy Department Beijing Normal UniversityBeijing 100875China

The BeiDou-3 global satellite navigation system(BDS-3)provides two radio determination satellite service(RDSS)positioning services for users,i.e.,the traditional RDSS(TRDSS)positioning of the BeiDou-2 regional satellite navigation system,and the comprehensive RDSS(CRDSS)positioning,which integrates the RDSS and radio navigation satellite *** published studies regarding the RDSS positioning service are few,we analyze and compare the performances of the two RDSS positioning ***,we systematically investigate the principles of the TRDSS and CRDSS positioning,and then analyze the evaluation methods in terms of their positioning accuracy,real time,and coverage ***,based on the BeiDou RDSS measured data,we evaluate the performances of the TRDSS and CRDSS *** with TRDSS positioning,CRDSS positioning exhibits the following:1)A significant increase in positioning accuracy,resulting in error improvement from 8 to 2 m and root mean square improvement from 3.13 to 0.85 m;in other words,the positioning error,constant deviation,and stability improve significantly.2)The real time reduces slightly from 1.1 to 1.8 ns,which is within the acceptable range.3)The coverage range expands from the areas of 62°E-145°E and 5°N-55°N to the areas of 50°E-170°E and 0°N-70°N,respectively.4)CRDSS positioning is not restricted by the constraints of the digital elevation database or the user elevation information and can thus solve the occlusion problem effectively.

关键词： TRDSS positioning CRDSS positioning positioning accuracy real time coverage range

Inhibitory Effects of Phenylacetic Acid on Proliferation of Human Pancreatic Carcinoma BXPC-3 Cells by the Regulation of Adenosine Deaminases Acting on RNA

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Chemical Research in Chinese Universities 2010年第6期26卷 964-968页

作者： JIANG Yao ren hui ZHANG Guang ZHANG Ling TIAN Xiao-feng JIA hui-jie HAN Li-ying TIAN Yu Department of General Surgery China-Japan Union Hospital of Jilin University Changchun 130033 P. R. China Department of General Surgery the Second Hospital of Jilin University Changchun 130041 P R. China Department of Thyroid Gland Surgery China-Japan Union Hospital of Jilin University Changehun 130033 P. R. China Prostate Diseases Prevention and Treatment Research Centre and Department of Pathophysiology Norman Bethune Medical School Jilin University Changchun 130021 P. R. China Department of Obstetrics and Gynecology the Second Hospital of Jilin University Changchun 130041 P. R. China Department of Neurosurgery China-Japan Union Hospital of Jilin University Changchun 130033 P. R. China

The effect and mechanism of phenylacetic acid on the proliferation of pancreatic carcinoma cells were investigated in cultured pancreatic carcinoma BXPC-3 cells by means of 3-（4,5-dimethylthiazol-2-yl）-2,5-diphenyltetrazolium bromide assay and flow cytometry *** results show that the treatment of pancreatic carcinoma cells with phenylacetic acid significantly inhibited the cell proliferation in time-dependent and dose-dependent *** proliferation of BXPC-3 cells was inhibited at the stage of S phase,the cells at the end stage of S phase were accumulated abundantly,and thus DNA synthesis could not be accomplished *** addition,the expression of adenosine deaminases acting on RNA（ADARs） mRNA in BXPC-3 cells and pancreatic carcinoma specimen were detected by *** been treated with phenylacetic acid,ADAR2 mRNA in BXPC-3 cells was significantly decreased,the differences were of statistical significance（P0.01）.Taken together,these results suggest that phenylacetic acid may likely regulate the proliferation of pancreatic carcinoma cells through the regulation of ADAR2 mRNA expression.

关键词： Pancreatic carcinoma Phenylacetic acid ADAR2 RNA editing

Ultrasonic Fatigue Damage Behavior of 304L Austenitic Stainless Steel Based on Micro-plasticity and Heat Dissipation

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Journal of Iron and Steel Research International 2015年第7期22卷 638-644页

作者： Chao HE ren-hui TIAN Yong-jie LIU Jiu-kai LI Qing-yuan WANG Key Laboratory of Energy Engineering Safety and Disaster Mechanics of Ministry of EducationCollege of Architecture and EnvironmentSichuan University

Very high cycle fatigue behavior （107 --109 cycles） of 304L austenitic stainless steel was studied with ultra- sonic fatigue testing system （20 kHz）. The characteristics of fatigue crack initiation and propagation were discussed based on the observation of surface plastic deformation and heat dissipation. It was found that micro-plasticity （slip markings） could be observed on the specimen surface even at very low stress amplitudes. The persistent slip mark- ings increased clearly along with a remarkable process of heat dissipation just before the fatigue failure. By detailed investigation using a scanning electron microscope and an infrared camera, slip markings appeared at the large grains where the fatigue crack initiation site was located. The surface temperature around the fatigue crack tip and the slip markings close to the fracture surface increased prominently with the propagation of fatigue crack. Finally, the cou- pling relationship among the fatigue crack propagation, appearance of surface slip markings and heat dissipation was analyzed for a better understanding of ultrasonic fatigue damage behavior.

关键词： very high cycle fatigue austenitic stainless steel micro-plasticity heat dissipation fatigue damage behavior

Large focal nodular hyperplasia is unresponsive to arterial embolization: A case report

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World Journal of Clinical Cases 2021年第32期9卷 9977-9981页

作者： hui ren Yin-Jie Gao Xue-Mei Ma Shao-Tang Zhou Department of Hepatobiliary and Liver Transplant Center The Fifth Medical CenterChinese People’s Liberation Army General HospitalBeijing 100039China

BACKGROUND Focal nodular hyperplasia(FNH)commonly occurs in women;it is usually asymptomatic and sometimes difficult to differentiate from hepatocellular carcinoma(HCC).CASE SUMMARY A large space-occupying lesion in the right lobe of the liver was incidentally detected in an adult man and diagnosed as *** arterial chemoembolization was applied once monthly for 2 years,but the lesion did not decrease in *** was revealed by biopsy to be *** years later,the patient underwent liver resection due to hemorrhage and the pathological examination confirmed *** For a space-occupying lesion,it is prerequisite to pathologically confirm the diagnosis and the corresponding intervention can be effective.

关键词： Focal nodular hyperplasia Large focal nodular hyperplasia Transarterial embolization Hepatocellular carcinoma Case report

Realizing Zinc Blende GaAs/AlGaAs Axial and Radial Heterostructure Nanowires by Tuning the Growth Temperature

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Journal of Materials Science & Technology 2011年第6期27卷 507-512页

作者： Jingwei Cuo hui Huang Xiaomin ren Xin Yan Shiwei Cai Wei Wang Yongqing Huang Qi Wang and Xi Zhang Key Laboratory of Information Photonics & Optical Communications Ministry of Education Beijing University of Posts and Telecommunications Beijing 100876 China

Vertical zinc blende GaAs/AlGaAs heterostructure nanowires were grown at different temperatures by metalorganic chemical vapor deposition via Au-assisted vapor-liquid-solid *** was found that radial growth can be enhanced by increasing the growth *** growth of radial heterostructure can be realized at temperature higher than 500℃,while the growth temperature of axial heterostructure is lower than 440℃.The room temperature photoluminescence properties of the nanowires were investigated and the relevant growth mechanism was discussed.

关键词： Nanowire GaAs AlGaAs Heterostructure Zinc blende