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Investigation of the infection route of HIV-associated cytomegalovirus retinitis

International Journal of Ophthalmology(English edition) 2025年第3期18卷 478-486页

作者： Jie Cai Zi-Kang Xie Dong-Yong Tang hui-Yi zuo Hao Liang Department of Ophthalmology the First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina

AIM:To investigate the etiology of ocular pathogens and to establish the various pathogens present in human immunodeficiency virus(HIV)patients with cytomegalovirus retinitis(CMVR).METHODS:A total of 17 HIV-infected patients with concomitant eye disorders were *** were divided into CMVR group(10 patients,18 eyes)and non-CMVR group(7 patients,9 eyes)based on clinical manifestations and the presence of cytomegalovirus(CMV)-DNA in ocular *** viral load of CMV was assessed using polymerase chain reaction in aqueous humor,vitreous fluid,and peripheral blood samples of patients in the CMVR ***,peripheral blood CD4+T cell counts were measured in both ***:In the CMVR group,the CMV-DNA load in the vitreous and aqueous humor samples was substantially higher than in the peripheral blood samples(P<0.01).CMVDNA load in the aqueous humor and vitreous samples of the two eyes in the CMVR group was determined to be statistically significant(10 patients,16 eyes,P=0.018,0.012).Peripheral blood CD4+T cell counts in the CMVR group were adversely linked with the CMV-DNA load in both the aqueous humor and peripheral blood(P=0.005,0.048).Compared with the non-CMVR group,the peripheral blood CD4+T cell count in the CMVR group decreased significantly(P=0.014).The peripheral blood CD4+T cell count exceeded 300 cells/μL in 85.71%of non-CMVR patients,whereas it was below 100 cells/μL in 90.00%of the CMVR *** intraocular specimens of the patients who underwent CMVR testing did not include any additional ***:In HIV-associated CMVR patients,there may exist alternative,yet unidentified,infection pathways for intraocular CMV in addition to the conventional *** substantial difference in CMV-DNA load between the eyes of most CMVR patients suggests that CMV may originate from different sources in each *** proportion of peripheral blood CD4+T cells in HIV patients is negatively correlated with the quantity of CMV viruses

关键词： cytomegalovirus retinitis acquired immunodeficiency syndrome human immunodeficiency virus

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An Efficient Boron Source Activation Strategy for the Low‑Temperature Synthesis of Boron Nitride Nanotubes

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Nano-Micro Letters 2025年第1期17卷 548-558页

作者： Ying Wang Kai Zhang Liping Ding Liyun Wu Songfeng E Qian He Nanyang Wang hui zuo Zhengyang Zhou Feng Ding Yue Hu Jin Zhang Yagang Yao National Laboratory of Solid State Microstructures College of Engineering and Applied SciencesJiangsu Key Laboratory of Artificial Functional Materialsand Collaborative Innovation Center of Advanced MicrostructuresNanjing UniversityNanjing 210093People’s Republic of China School of Electronic Information and Artificial Intelligence Shaanxi University of Science&TechnologyXian 710000People’s Republic of China College of Bioresources Chemical and Materials Engineering Shaanxi University of Science&TechnologyXian 710000People’s Republic of China Key Laboratory of Carbon Materials of Zhejiang Province College of Chemistry and Materials EngineeringWenzhou UniversityWenzhou 325000People’s Republic of China Shenzhen Institutes of Advanced Technology Chinese Academy of SciencesShenzhen 518000People’s Republic of China College of Chemical and Molecular Engineering Peking UniversityBeijing 100871People’s Republic of China

Lowering the synthesis temperature of boron nitride nanotubes(BNNTs)is crucial for their *** primary reason for adopting a high temperature is to enable the effective activation of highmelting-point solid *** this study,we developed a novel approach for efficiently activating boron by introducing alkali metal compounds into the conventional MgO–B *** approach can be adopted to form various low-melting-point AM–Mg–B–O growth *** growth systems have improved catalytic capability and reactivity even under low-temperature conditions,facilitating the synthesis of BNNTs at temperatures as low as 850℃.In addition,molecular dynamics simulations based on density functional theory theoretically demonstrate that the systems maintain a liquid state at low temperatures and interact with N atoms to form BN *** findings offer novel insights into the design of boron activation and are expected to facilitate research on the low-temperature synthesis of BNNTs.

关键词： Boron nitride nanotubes Low-temperature Boron activation Density functional theory

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社区老年人咀嚼功能评估问卷的编制及信效度检验

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护理研究 2025年第3期39卷 428-432页

作者：张瑞郭三兰左慧马静华中科技大学同济医学院附属同济医院湖北430030

目的:编制社区老年人咀嚼功能评估问卷并进行信效度检验,为社区老年人咀嚼功能的评估提供工具。方法:以口腔健康状况测量理论模型为指导,通过文献分析、小组讨论形成初稿,进行2轮专家函询和预调查,形成最终版问卷;采用便利抽样法,选取2... 详细信息

目的:编制社区老年人咀嚼功能评估问卷并进行信效度检验,为社区老年人咀嚼功能的评估提供工具。方法:以口腔健康状况测量理论模型为指导,通过文献分析、小组讨论形成初稿,进行2轮专家函询和预调查,形成最终版问卷;采用便利抽样法,选取2021年9月—2022年3月在湖北省某社区卫生中心参加健康体检的180名老年人为调查对象,对问卷进行项目分析、探索性因子分析及信效度检验;2022年4月—10月另选取256名老年人作为调查对象,进行验证性因子分析。结果:形成的社区老年人咀嚼功能评估问卷共包含17个条目,探索性因子分析提取出3个公因子,累计贡献率为78.40%;验证性因子分析显示,模型拟合度可。问卷总体内容效度为0.92,各条目的内容效度为0.83~1.00,Cronbach'sα系数为0.919,分半信度为0.846。结论:编制的社区老年人咀嚼功能评估问卷具有良好的信效度,可作为社区老年人咀嚼功能的评估工具。

关键词：社区老年人咀嚼功能专家函询问卷信度效度

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Road model prediction based unstructured road detection

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Journal of Zhejiang University-Science C(Computers and Electronics) 2013年第11期14卷 822-834页

作者： Wen-hui zuo Tuo-zhong YAO Department of Information Science and Electronic Engineering Zhejiang University Ningbo Institute of Materials Technology&Engineering Chinese Academy of Sciences

Vision-based road detection is an important research topic in different areas of computer vision such as the autonomous navigation of mobile *** outdoor unstructured environments such as villages and deserts,the roads are usually not well-paved and have variant colors or texture *** region- or edge-based approaches,however,are effective only in specific environments,and most of them have weak adaptability to varying road types and *** this paper we describe a novel top-down based hybrid algorithm which properly combines both region and edge cues from the *** main difference between our proposed algorithm and previous ones is that,before road detection,an off-line scene classifier is efficiently learned by both low- and high-level image cues to predict the unstructured road *** scene classification can be considered a decision process which guides the selection of the optimal solution from region- or edge-based approaches to detect the ***,a temporal smoothing mechanism is incorporated,which further makes both model prediction and region classification more *** results demonstrate that compared with traditional region- and edge-based algorithms,our algorithm is more robust in detecting the road areas with diverse road types and varying appearances in unstructured conditions.

关键词： Road detection Surface layout Road model prediction Temporal smoothing

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A highly selective and sensitive fluorescent chemosensor for Zn^(2+)

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Chinese Chemical Letters 2008年第10期19卷 1240-1243页

作者： Xiu Ying Zhang zuo hui Wang Lin Yang School of Chemistry and Environmental Science Key Ltlboratory for Environmental Pallution Control Technology of Henan Province Henan Normal University Xinxiang 453007 China

A new selective Zn^2＋ fluorescent chemosensor, o-vanillin-4-ethoxybenzoylhydrazone （1）, was designed and prepared. Free 1 mainly displayed very weak fluorescence at 480 nm upon excitation at 403 nm. It displayed high selectivity for Zn^2＋ and had a 518- fold fluorescent enhancement upon binding of Zn^2＋, while the other cation ions had only little influence on the fluorescence of 1. Mechanism of enhancement of l＇s fluorescence by Zn^2＋ was briefly discussed.

关键词： Chemosensor Zinc ion Fluorescence enhancement N-Acylhydrazone

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Phase Equilibria in AI-Ca-Li System： a Thermodynamic Description

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Chemical Research in Chinese Universities 2013年第6期29卷 1167-1172页

作者： WANG Kun YIN hui-qin CHENG Jin-hui zuo Yong XIE Lei-dong University of Chinese Academy of Sciences Beijing 100049 P.R.China

Relations of equilibrium phases in the Al-Ca-Li system were calculated by means of the CALPHAD （calculation of phase diagram） method. The reported thermodynamic model parameters for all the constituent binary systems were directly used in the present calculation. A novel thermodynamic description for the three ternary intermetallic compounds（τ1 τ2 and τ3） was made on the basis of experimental phase equilibria in the Al-Ca-Li system. Comparison between the calculated and experimental phase equilibria shows that we have successfully derived a set of self-consistent thermodynamic parameters for the Al-Ca-Li system. These parameters were then used for the prediction of the selected isothermal and isopleth sections and projected liquidus surface of this ternary system over the entire composition range.

关键词： Phase diagram Thermodynamics Alloy

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Risk of group aggregative behavior during COVID-19 outbreak: A case report

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World Journal of Clinical Cases 2021年第1期9卷 170-174页

作者： hui zuo Zhi-Bing Hu Feng Zhu Infection Control and Administration Guangzhou Twelfth People’s HospitalGuangzhou 510620Guangdong ProvinceChina Molecular Epidemiology Research Group Guangzhou Twelfth People’s HospitalGuangzhou 510620Guangdong ProvinceChina Central Laboratory Guangzhou Occupation Disease Preventive and Treatment CentreGuangzhou 510620Guangdong ProvinceChina

BACKGROUND At the end of 2019,a new epidemic of viral pneumonia emerged in China and was determined to be caused by a novel coronavirus,which was named coronavirus disease 2019(COVID-19)by the World Health *** epidemic quickly spread,causing a worldwide *** and clinicians across the globe have shifted their research efforts towards understanding the virus itself and its *** SUMMARY In mid-January 2020,a Chinese family made a visit to a local city,and within the next 2 wk one after another fell ill with *** the beginning of their first illness onset,the family had eaten in a restaurant,which led to the subsequent illness onset in another two *** cases were diagnosed as COVID-19 by real-time fluorescent reverse transcription-polymerase chain *** investigation showed that the transmission chain was *** This chain of social exposure highlights the danger of group aggregative behavior for spread of COVID-19.

关键词： COVID-19 Epidemiological investigation Group aggregative behavior Novel coronavirus Pandemic Social exposure Case report

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Endodontic management of the maxillary first molars with two root canals: A case report and review of the literature

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World Journal of Clinical Cases 2019年第1期7卷 79-88页

作者： Jie Liu Ke-Hua Que zuo-hui Xiao Wen Wen Department of Endodontics College of Stomatology Tianjin Medical University Department of Geriatric Dentistry National Engineering Laboratory for Digital and Material Technology of Stomatology Laboratory of Biomedical Materials Peking University School and Hospital of Stomatology Department of Stomatology Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital

BACKGROUND The complex anatomy of the maxillary first molars has always been a major challenge for complete root canal treatment in endodontic therapy. Here, we present two cases of maxillary first molars, each with only two root canals, which have been rarely reported. We also perform a literature review of maxillary first molar *** SUMMARY The two patients were referred to the hospital after 1) finding a cavity in their tooth with a color change and, 2) a toothache during mastication, *** of these cases were diagnosed as apical periodontitis by X-ray imaging and cone beam computed tomography(CBCT). Non-surgical endodontic therapy was performed with the assistance of a dental operating microscope(DOM). CBCT showed rare but accurate images of both patients, each with two root canals and two roots in their maxillary first molars. Both roots were located in the buccal in the palatal direction, and each root had only one clear root canal. In addition,each maxillary first molar in both patients was symmetrical to that on the opposing side with only two separate root canals. Non-surgical endodontic therapy was performed with the assistance of a DOM. Finally, the teeth were restored using composite resin and the patients were satisfied with the *** Making full use of CBCT and DOM would contribute to helping dentists make correct diagnoses and successfully treat teeth with rare root canal morphologies.

关键词： Root canal anatomy Maxillary first molar Cone beam computed tomography Dental operating microscope Endodontic therapy Case report

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Hydrocarbon generation history constrained by thermal history and hydrocarbon generation kinetics:A case study of the Dongpu Depression,Bohai Bay Basin,China

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Petroleum Science 2022年第2期19卷 472-485页

作者： Mei-Hua Yang Yin-hui zuo Kang-Nan Yan Yong-Shui Zhou Yun-Xian Zhang Cheng-Fu Zhang State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Chengdu University of TechnologyChengduSichuan 610059China Energy&Geoscience Institute University of UtahSalt Lake CityUT84108USA Research Institute of Exploration and Development Zhongyuan OilfieldSINOPECPuyangHenan 457001China

With the increasing exploration and development of typical hydrocarbon-rich depressions,such as the Dongpu Depression,the exploitation difficulty of shallow formations is *** is an urgent need to clarify the hydrocarbon generation mode and hydrocarbon generation histories in deep *** this study,a gold tube-autoclave closed system was used to simulate the hydrocarbon generation processes and establish the hydrocarbon generation mode of different types of ***,constrained by the thermal history and hydrocarbon generation kinetics,hydrocarbon generation histories were *** results show that hydrocarbon generation evolution can be divided into five stages,and the maturity of each stage is *** hydrocarbon generation history of the source rocks of the Shahejie 3 Formation mainly dates from the early depositional period of the Shahejie 1 Formation to the middle depositional period of the Dongying *** generation history constrained by thermal history and hydrocarbon generation kinetics is more in line with actual geological ***,this research can provide important hydrocarbon generation parameters for deep oil and gas exploration and exploitation of the Shahejie 3 Formation in the Dongpu Depression.

关键词： Dongpu depression Thermal history Hydrocarbon generation kinetics Hydrocarbon generation mode Hydrocarbon generation history

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Extracting angle-domain common-image gathers in VTI media using ansiotropic-Helmholtz P/S wave-mode decomposition

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Petroleum Science 2023年第3期20卷 1546-1561页

作者： Le-Le Zhang Yang Zhao Lu Liu Ke Chen Jia-hui zuo Yi-Xin Wang Ji-Dong Yang State Key Laboratory of Petroleum Resource and Prospecting Unconventional Petroleum Research InstituteChina University of PetroleumBeijing102249China Aramco Beijing Research Center Aramco AsiaBejing100102China Department of Geophysics China University of Petroleum(East China)QingdaoShandong266580China

Common-image gathers are extensively used in amplitude versus angle(AVA)and migration velocity analysis(MVA).The current state of methods for anisotropic angle gathers extraction use slant-stack,local Fourier transform or low-rank approximation,which requires much *** on an anisotropic-Helmholtz P/S wave-mode decomposition method,we propose a novel and efficient approach to produce angle-domain common-image gathers(ADCIGs)in the elastic reverse time migration(ERTM)of VTI *** start with,we derive an anisotropic-Helmholtz decomposition operator from the Christoffel equation in VTI media,and use this operator to derive the decomposed formulations for anisotropic P/S ***,we employ the first-order Taylor expansion to calculate the normalized term of decomposed formulations and obtain the anisotropic-Helmholtz decomposition method,which generates the separated P/S wavefields with correct amplitudes and ***,we develop a novel way that uses the anisotropic-Helmholtz decomposition operator to define the polari-zation angles for anisotropic P/S waves and substitute these angles to decomposing *** polarization angles are then calculated directly from the separated vector P-and S-wavefields and converted to the phase *** ADCIGs are thusly produced by applying the phase angles to VTI *** addition,we develop a concise approximate expression of residual moveout(RMO)for PP-reflections of flat reflectors in VTI media,which avoids the complex transformations between the group angles and the phase *** approximate RMO curves show a good agreement with the exact solution and can be used as a tool to assess the migration velocity *** demonstrated by two selected examples,our ADCIGs not only produce the correct kinematic responses with regards to different velocity pertubatation,but also generate the reliable amplitude responses versus different *** final stacking images of ADCIGs data exhibit the identical im

关键词： Helmholtz decomposition Angle gathers Anisotropy Elastic-RTM

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