检索结果-南通市图书馆

Deep Geothermal: The ‘Moon Landing' Mission in the Unconventional Energy and Minerals Space

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Earth Science 2015年第1期26卷 2-10页

作者： Klaus Regenauer-Lieb Andrew Bunger hui tong chua Arcady Dyskin Florian Fusseis Oliver Gaede Rob Jeffrey Ali Karrech Thomas Kohl Jie Liu Vladimir Lyakhovsky Elena Pasternak Robert Podgorney Thomas Poulet Sheik Rahman Christoph Schrank Mike Trefry Manolis Veveakis Bisheng Wu David A.Yuen Florian Wellmann Xi Zhang School of Petroleum Engineering University of New South WalesSydney NSW 2052Australia Earth Science and Resource Engineering CSIROKensington WA 6151Australia School of Earth and Environment The University of Western AustraliaPerth WA 6000Australia Department of Civil and Environmental Engineering & Department of Chemical and Petroleum Engineering University of PittsburghPittsburghPennsylvaniaUSA School of Geosciences University of EdinburghEdinburghUK Science and Engineering Faculty School of EarthEnvironmental and Biological SciencesEarth SystemsQueensland University of TechnologyBrisbaneAustralia Karlsruhe Institute of Technology KarlsruheGerman School of Earth Science and Geological Engineering Sun Yat-Sen University Geological Survey of Israel Jerusalem 95501Israel Idaho National Laboratory Idaho FallsUSA Land and Water CSIROFloreat Park WA 6014Australia School of Environmental Studies China University of Geosciences Department of Earth Sciences and Minnesota Supercomputing Institute University of MinnesotaMinneapolis MN 55455USA Aachen Institute for Advanced Study in Computational Engineering Science (AICES) RWTH Aachen University52062 AachenGermany

Deep geothermal from the hot crystalline basement has remained an unsolved frontier for the geothermal industry for the past 30 years. This poses the challenge for developing a new unconventional geomechanics approach to stimulate such reservoirs. While a number of new unconventional brittle techniques are still available to improve stimulation on short time scales, the astonishing richness of failure modes of longer time scales in hot rocks has so far been overlooked. These failure modes represent a series of microscopic processes： brittle microfracturing prevails at low temperatures and fairly high deviatoric stresses, while upon increasing temperature and decreasing applied stress or longer time scales, the failure modes switch to transgranular and intergranular creep fractures. Accordingly, fluids play an active role and create their own pathways through facilitating shear localization by a process of time-dependent dissolution and precipitation creep, rather than being a passive constituent by simply following brittle fractures that are generated inside a shear zone caused by other localization mechanisms. We lay out a new theoretical approach for the design of new strategies to utilize, enhance and maintain the natural permeability in the deeper and hotter domain of geothermal reservoirs. The advantage of the approach is that, rather than engineering an entirely new EGS reservoir, we acknowledge a suite of creep-assisted geological processes that are driven by the current tectonic stress field. Such processes are particularly supported by higher temperatures potentially allowing in the future to target commercially viable combinations of temperatures and flow rates.

关键词： geothermal energy enhanced geothermal systems fracture mechanics creep dissolution precipitation.

在线全文

学校读者我要写书评

暂无评论

低温余热驱动多效蒸馏与脱盐技术

Microglia lactylation in relation to central nervous system diseases

作者： (伊朗)比将·拉希米(Bijan Rahimi)，(澳)蔡慧中(hui tong chua)

来源：南通市图书馆图书评论

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第1期20卷 29-40页

作者： hui Yang Nan Mo Le tong Jianhong Dong Ziwei Fan Mengxian Jia Juanqing Yue Ying Wang School of Pharmacy Hangzhou Normal UniversityHangzhouZhejiang ProvinceChina Department of Clinical Laboratory The Fourth Clinical Medical College of Zhejiang University of Traditional Chinese Medicine(Hangzhou First People’s Hospital)HangzhouZhejiang ProvinceChina College of Medical Veterinary and Life SciencesUniversity of GlasgowGlasgowUK Department of Orthopedics(Spine Surgery) the First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiang ProvinceChina Department of Pathology Affiliated Hangzhou First People’s HospitalWestlake University School of MedicineHangzhouZhejiang ProvinceChina Department of Clinical Research Center Affiliated Hangzhou First People’s HospitalWestlake University School of MedicineHangzhouZhejiang ProvinceChina

The development of neurodegenerative diseases is closely related to the disruption of central nervous system ***,as innate immune cells,play important roles in the maintenance of central nervous system homeostasis,injury response,and neurodegenerative *** has been considered a metabolic waste product,but recent studies are revealing ever more of the physiological functions of *** is an important pathway in lactate function and is involved in glycolysis-related functions,macrophage polarization,neuromodulation,and angiogenesis and has also been implicated in the development of various *** review provides an overview of the lactate metabolic and homeostatic regulatory processes involved in microglia lactylation,histone versus non-histone lactylation,and therapeutic approaches targeting ***,we summarize the current research on microglia lactylation in central nervous system diseases.A deeper understanding of the metabolic regulatory mechanisms of microglia lactylation will provide more options for the treatment of central nervous system diseases.

关键词： brain central nervous system glycolysis immune response inflammation lactate metabolism lactate lactylation microglia neurodegenerative diseases

Small extracellular vesicles derived from human induced pluripotent stem cell-differentiated neural progenitor cells mitigate retinal ganglion cell degeneration in a mouse model of optic nerve injury

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第2期20卷 587-597页

作者： tong Li hui-Min Xing Hai-Dong Qian Qiao Gao Sheng-Lan Xu Hua Ma Zai-Long Chi State Key Laboratory of Ophthalmology Optometry and Visual ScienceEye HospitalWenzhou Medical UniversityWenzhouZhejiang ProvinceChina National Clinical Research Center for Ocular Diseases Eye HospitalWenzhou Medical UniversityWenzhouZhejiang ProvinceChina

Several studies have found that transplantation of neural progenitor cells(NPCs)promotes the survival of injured ***,a poor integration rate and high risk of tumorigenicity after cell transplantation limits their clinical *** extracellular vesicles(sEVs)contain bioactive molecules for neuronal protection and *** studies have shown that stem/progenitor cell-derived sEVs can promote neuronal survival and recovery of neurological function in neurodegenerative eye diseases and other eye *** this study,we intravitreally transplanted sEVs derived from human induced pluripotent stem cells(hiPSCs)and hiPSCs-differentiated NPCs(hiPSC-NPC)in a mouse model of optic nerve *** results show that these intravitreally injected sEVs were ingested by retinal cells,especially those localized in the ganglion cell *** with hiPSC-NPC-derived sEVs mitigated optic nerve crush-induced retinal ganglion cell degeneration,and regulated the retinal microenvironment by inhibiting excessive activation of *** analysis further revealed that hiPSC-NPC derived sEVs transported neuroprotective and anti-inflammatory miRNA cargos to target cells,which had protective effects on RGCs after optic nerve *** findings suggest that sEVs derived from hiPSC-NPC are a promising cell-free therapeutic strategy for optic neuropathy.

关键词： exosome miRNA neural progenitor cell neurodegeneration neuroinflammation neuroprotection optic nerve crush optic neuropathy retinal ganglion cell small extracellular vesicles

Metal-organic frameworks with dinuclear metal centers for synergistically boosting CO2 photoreduction

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2025年第01期 201-208页

作者： hui-Feng Wang Wen-Jie Shi Yu-Xin Yang Bao-Xia Dong tong-Bu Lu Di-Chang Zhong School of Chemistry and Chemical Engineering Yangzhou University Institute for New Energy Materials and Low Carbon Technologies School of Materials Science and Engineering Tianjin University of Technology

Dinuclear metal synergistic catalysis （DMSC） has been proved powerful in boosting CO2reduction,while this has not been achieved in heterogeneous catalysts with long-range order *** this study,we,by introduction of metal catalytic centers into an indium-based metal-organic framework （MOF）,obtained a series of isostructural In-MOFs,including three MOFs with mononuclear metal catalytic center （M-In）,three MOFs with dinuclear homometallic catalytic centers （MM-In）,and three MOFs with dinuclear heterometallic catalytic centers (MM’-In,M/M’=Co（II）,Ni（II）,Zn（II）).It was found that all these MOFs can serve as catalysts for photochemical CO2reduction to *** with M-In,the catalytic activities of MM-In were obviously enhanced,and that of MM’-In was further significantly *** example,the CO yield of Co Zn-In reaches a record value of 12,700μmol g-1h-1,which is 4.0,8.1,9.4,and 18.6-fold higher than that of Co Co-In,Zn Zn-In,Co-In,and Zn-In,***,the catalytic activities of Co Ni-In and Ni Zn-In also show different fold increase than those of corresponding dinuclear homometallic and mononuclear metallic *** results of control experiments and theoretical calculation reveal that the higher catalytic activities of MM-In over M-In can be ascribed to the DMSC effect,and the higher catalytic activity of MM’-In over MM-In can be ascribed to the strengthened DMSC *** work reveals the relationship between DMSC effect and bimetal centers in CO2reduction,which provides new insights into the DMSC and paves a new way to design highly active catalysts for photochemical CO2reduction.

关键词：

同方期刊数据库

平台灵活就业人员劳动权益保护的立法困境与对策

在线全文

学校读者我要写书评

暂无评论

河北学刊 2025年第1期45卷 172-182页

作者：冯辉贺小桐对外经济贸易大学法学院

以人力资源和社会保障部颁布的规范性文件为代表,中国关于平台灵活就业人员劳动权益保护的立法取得了重要的成就,但也存在着程序重于实体、形式重于实质、立法重点与实践需要有所偏离等困境。应以实质公平为理念,促进平台与灵活就业人... 详细信息

以人力资源和社会保障部颁布的规范性文件为代表,中国关于平台灵活就业人员劳动权益保护的立法取得了重要的成就,但也存在着程序重于实体、形式重于实质、立法重点与实践需要有所偏离等困境。应以实质公平为理念,促进平台与灵活就业人员的利益平衡,在尊重平台组织管理权力的基础上激励其履行社会责任;合理规制平台的利益分配权和劳动规则制定权,强化平台利益分配和规则制定的公平性;完善社会保险、职业伤害保障和纠纷解决领域的公共产品供给。

关键词：平台灵活就业人员劳动权益保护利益分配劳动规则实质公平

Exploring gut microbiota as a novel therapeutic target in Crohn’s disease: Insights and emerging strategies

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2025年第2期31卷 147-156页

作者： tong Qiao Xian-hui Wen Department of Clinical Medicine Jinan UniversityGuangzhou 510632Guangdong ProvinceChina College of Life Science and Technology Jinan UniversityGuangzhou 510632Guangdong ProvinceChina

Extensive research has investigated the etiology of Crohn’s disease(CD),encompassing genetic predisposition,lifestyle factors,and environmental ***,the gut microbiome,recognized as the human body’s second-largest gene pool,has garnered significant attention for its crucial role in the patho-genesis of *** paper investigates the mechanisms underlying CD,focusing on the role of‘creeping fat’in disease progression and exploring emerging therapeutic strategies,including fecal microbiota transplantation,enteral nutri-tion,and therapeutic *** fat has been identified as a unique patho-logical feature of CD and has recently been found to be associated with dysbiosis of the gut *** characterize this dysbiotic state by identi-fying key microbiome-bacteria,fungi,viruses,and archaea,and their contributions to CD ***,this paper reviews contemporary therapies,empha-sizing the potential of biological therapies like fecal microbiota transplantation and dietary *** elucidating the complex interactions between host-microbiome dynamics and CD pathology,this article aims to advance our under-standing of the disease and guide the development of more effective therapeutic strategies for managing CD.

关键词： Crohn’s disease Gut microbiome Dysbiosis Creeping fat Fecal microbiota transplantation

SURFACE EFFECT ON NANOSIZED VOID GROWTH IN A RIGID-PERFECTLY PLASTIC MATERIAL

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Mechanica Solida Sinica 2008年第1期21卷 9-14页

作者： tong hui Yiheng Chen School of Aerospace MOE Xi＇an Jiaotong University Xi＇an 710049 China

The influence of the surface effect on the nanosized spherical void growth in a rigidperfectly plastic material is analyzed and the mechanism of the nanosized void growth with high triaxiality is given. Based on the Rice and Tracey model for a macro void growth, the present model is proposed to account for the nanosized void growth under a uniform remote strain rate field with consideration on the surface effect. It is concluded that the surface effect yields an evident resistant influence on the nanosized void growth. That is, this influence decays as the void radius increases. With high triaxiality, the nanosized void growth is divided into two stages： the initial stage and the mature stage. At the first stage, the void grows slowly and the influence of surface effect is relatively weak, whereas at the second stage, the influence is significant and the void grows drastically.

关键词： nanosized void extended variational principle void growth surface effect high triaxiality

Unraveling the significance of cobalt on transformation kinetics,crystallography and impact toughness in high-strength steels

在线全文

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 380-390页

作者： Yishuang Yu Jingxiao Zhao Xuelin Wang hui Guo Zhenjia Xie Chengjia Shang Collaborative Innovation Center of Steel Technology University of Science and Technology BeijingBeijing 100083China School of Materials Science and Engineering Shanghai Jiao Tong UniversityShanghai 200240China State Key Laboratory for Advanced Metals and Materials University of Science and Technology BeijingBeijing 100083China

This work reveals the significant effects of cobalt(Co)on the microstructure and impact toughness of as-quenched highstrength steels by experimental characterizations and thermo-kinetic *** results show that the Co-bearing steel exhibits finer blocks and a lower ductile-brittle transition temperature than the steel without ***,the Co-bearing steel reveals higher transformation rates at the intermediate stage with bainite volume fraction ranging from around 0.1 to *** improved impact toughness of the Co-bearing steel results from the higher dense block boundaries dominated by the V1/V2 variant ***,the addition of Co induces a larger transformation driving force and a lower bainite start temperature(BS),thereby contributing to the refinement of blocks and the increase of the V1/V2 variant *** findings would be instructive for the composition,microstructure design,and property optimization of high-strength steels.

关键词： high-strength steel cobalt transformation kinetics crystallography impact toughness