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The connection between radio and γ-ray emission in Fermi/LAT blazars

Research in Astronomy and Astrophysics 2012年第11期12卷 1475-1485页

作者： Xu-Liang Fan Jin-Ming Bai Hong-Tao Liu Liang Chen Neng-hui liao National Astronomical Observatories / Yunnan Observatory Chinese Academy of SciencesKunming 650011 China Key Laboratory for the Structure and Evolution of Celestial Objects Chinese Academy ofSciences Kunming 650011 China Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoriesChinese Academy of Sciences Shanghai 200030 China Graduate University of Chinese Acaciemy of Sciences Beijing 100049 China

We collect the second Large Area Telescope AGN catalog （2LAC） and Monitor of Jets in AGN with VLBA Equipment （MOJAVE） quasi-simultaneous data to investigate the radio-γ connection of blazars. The cross sample contains 166 sources. The statistical analysis based on this sample confirms positive correlations between these two bands, but the correlations become weaker as the γ-ray energy increases. The statistical results between various parameters show negative correla- tions of γ-ray photon spectral index with γ-ray loudness for both Flat Spectrum Radio Quasars （FSRQs） and BL Lacertae objects, positive correlations of γ-ray variability index with the γ-ray loudness for FSRQs, a negative correlation of the γ-ray variabil- ity index with the γ-ray photon spectral index for FSRQs, and negative correlations of γ-ray photon spectral index with γ-ray luminosity for FSRQs. These results suggest that the γ-ray variability may be due to changes inside the γ-ray emission region like the injected power, rather than changes in the photon density of the external radiation fields, and the variability amplitude tends to be larger as the γ-rays are closer to the high energy peak of the spectral energy distribution （SED）. No correlation of variabil- ity index found for BL Lacertae objects implies that variability behavior may differ below and above the peak energy.

关键词： BL Lacertae objects general -- galaxies: jets -- quasars general -- radio continuum galaxies -- gamma rays observations

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城市河道河口闸站的运行工况及控制运用

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水利科学与寒区工程 2024年第2期7卷 97-100页

作者：魏玉翠薛晶吴倩廖辉吕俊华镇江市工程勘测设计研究院有限公司江苏镇江212003 镇江新区丁卯街道办事处江苏镇江212003

为满足新竹河闸站水生态、应急以及行洪等多种需求,在统筹兼顾除害与兴利,局部服从全局,兴利服从除害的调度控制运行原则下,对新竹河闸站各种运行工况进行分析,得出各个工况运行标准,使得闸站尽可能利用有利的水动力因素,实行灵活调度... 详细信息

为满足新竹河闸站水生态、应急以及行洪等多种需求,在统筹兼顾除害与兴利,局部服从全局,兴利服从除害的调度控制运行原则下,对新竹河闸站各种运行工况进行分析,得出各个工况运行标准,使得闸站尽可能利用有利的水动力因素,实行灵活调度和实时调度,尽可能实现最优经济运行,可为类似工程提供参考。

关键词：城市河道闸站控制运用运行工况

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医护合作——快速康复模式在单孔腹腔镜上尿路重建围手术期的应用研究

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中华腔镜泌尿外科杂志(电子版) 2024年第3期18卷 266-270页

作者：夏慧廖慧戴艳萍吴俊萍杨诚李建雄刘存东南方医科大学第三附属医院泌尿外科

目的探讨医护合作——快速康复模式在单孔腹腔镜上尿路重建围手术期的临床效果。方法选取2021年1月至2022年1月于南方医科大学第三附属医院行单孔腹腔镜上尿路重建术的50例患者作为研究对象，随机分为对照组和观察组，每组25例。对照... 详细信息

目的探讨医护合作——快速康复模式在单孔腹腔镜上尿路重建围手术期的临床效果。方法选取2021年1月至2022年1月于南方医科大学第三附属医院行单孔腹腔镜上尿路重建术的50例患者作为研究对象，随机分为对照组和观察组，每组25例。对照组患者行围术期常规康复，观察组行围术期医护合作——快速康复模式。评价两组患者术后康复情况、并发症发生情况、对护理工作满意程度评价及术后生活质量。结果在康复指标方面，术后首次下床时间、肛门排气时间，观察组均早于对照组（P0.05）。观察组对护理工作的满意程度及出院后生活质量评分均高于对照组（P<0.05）。结论快速康复能有效缩短围术期单孔腹腔镜下上尿路重建手术患者的首次下床活动、肛门排气时间，因而减少住院时间和费用，增加患者对康复的信心，对护理工作的满意程度，进而提高患者术后生活质量，值得临床推广。

关键词：快速康复外科(ERAS) 单孔腹腔镜上尿路重建术医护合作围术期

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Silencing Huwe1 reduces apoptosis of cortical neurons exposed to oxygen-glucose deprivation and reperfusion

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Neural Regeneration Research 2019年第11期14卷 1977-1985页

作者： Guo-Qian He Wen-Ming Xu hui-Juan liao Chuan Jiang Chang-Qing Li Wei Zhang Department of Pediatrics Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University)Ministry of EducationWest China Second University HospitalSichuan UniversityChengduSichuan ProvinceChina Joint Laboratory of Reproductive Medicine Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University)Ministry of EducationWest China Second University HospitalSichuan UniversityChengduSichuan ProvinceChina Department of Neurology The Second Affiliated Hospital of Chongqing Medical UniversityChongqingChina Department of Medical Oncology Sichuan Cancer Hospital & InstituteSichuan Cancer CenterCancer Hospital Affiliated to School of MedicineUniversity of Electronic Science and Technology of ChinaChengduSichuan ProvinceChina

HECT, UBA and WWE domain-containing 1(Huwe1), an E3 ubiquitin ligase involved in the ubiquitin-proteasome system, is widely expressed in brain tissue. Huwe1 is involved in the turnover of numerous substrates, including p53, Mcl-1, Cdc6 and N-myc, thereby playing a critical role in apoptosis and neurogenesis. However, the role of Huwe1 in brain ischemia and reperfusion injury remains unclear. Therefore, in this study, we investigated the role of Huwe1 in an in vitro model of ischemia and reperfusion injury. At 3 days in vitro, primary cortical neurons were transduced with a control or shRNA-Huwe1 lentiviral vector to silence expression of Huwe1. At 7 days in vitro, the cells were exposed to oxygen-glucose deprivation for 3 hours and reperfusion for 24 hours. To examine the role of the c-Jun N-terminal kinase(JNK)/p38 pathway, cortical neurons were pretreated with a JNK inhibitor(SP600125) or a p38 MAPK inhibitor(SB203508) for 30 minutes at 7 days in vitro, followed by ischemia and reperfusion. Neuronal apoptosis was assessed by TUNEL assay. Protein expression levels of JNK and p38 MAPK and of apoptosis-related proteins(p53, Gadd45 a, cleaved caspase-3, Bax and Bcl-2) were measured by western blot assay. Immunofluorescence labeling for cleaved caspase-3 was performed. We observed a significant increase in neuronal apoptosis and Huwe1 expression after ischemia and reperfusion. Treatment with the shRNA-Huwe1 lentiviral vector markedly decreased Huwe1 levels, and significantly decreased the number of TUNEL-positive cells after ischemia and reperfusion. The silencing vector also downregulated the pro-apoptotic proteins Bax and cleaved caspase-3, and upregulated the anti-apoptotic proteins Gadd45 a and Bcl-2. Silencing Huwe1 also significantly reduced p-JNK levels and increased p-p38 levels. Our findings show that downregulating Huwe1 affects the JNK and p38 MAPK signaling pathways as well as the expression of apoptosis-related genes to provide neuroprotection during ische

关键词： nerve regeneration ischemic stroke oxygen-glucose deprivation and reperfusion ischemia/reperfusion cortical neuron ubiquitin proteasome system Huwe1 apoptosis therapeutic targets cell culture cell death neural regeneration

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Classification and influencing factors of rural elderly's vulnerability to health-related poverty in central and western regions of China

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Global Health Journal 2021年第3期5卷 135-143页

作者： Qin Xiang Chaoyang Yan Ying Ma hui liao Jing Wang School of Medicine and Health Management Tongji Medical CollegeHuazhong University of Science and TechnologyHangkong Road 13WuhanHubei 430030China Research center for Rural Health Services Hubei Province Key Research Institute of Humanities and Social SciencesHangkong Road 13WuhanHubei 430030China

Objective:To calculate the health poverty vulnerability index of elderly households in rural areas of central and western China,and then to classify these samples,lastly to decompose their influencing ***:First,based on survey data in 2018,the three-stage feasible generalized least squares was used to calculate the health poverty vulnerability index of elderly households,and then combined with whether the household income was below the poverty line and whether the family was healthy poverty vulnerability,the sample households were divided into four categories,and then used multiple unordered logistic regression to analyze various types of influencing factors,and finally used the Shapley index to decompose the contribution of each influencing ***:The average vulnerability of health poverty was 0.5979±0.25199,with 1169 households greater than or equal to 0.5,accounting for 63.26%;the number of households stuck in poverty,temporary poverty,potential poverty,and escaped from poverty were 489,300,680,and 379 households,accounting for 26.46%,16.23%,36.80%,and 20.51%of the total sample;compared with escaped from poverty families,the three variables of marital status,the number of chronically ill patients,and the number of annual hospitalizations were the common influencing factors of other three types families;The Shapley decomposition showed that the interviewees’education level and family members engaged in non-agricultural work have contributed significantly to the three types,however two indicators:time required to visit a medical institution and self-assessment of health status of the main interviewees showed great differences in different types of ***:Rural elderly households have a high level of vulnerability to health poverty;potential poverty households and persistent poverty households account for a large proportion,and continuous intervention should be carried out;it is necessary to unify the implementation of basic pover

关键词： Health-related poverty Vulnerability Measurement Classification Influencing factors Shapley decomposition

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Comprehensive application of modern technologies in precise liver resection

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Hepatobiliary & Pancreatic Diseases International 2013年第3期12卷 244-250页

作者： Nian-Song Qian Yong-hui liao Shou-Wang Cai Vikram Raut Jia-Hong Dong Department of Hepatobiliary Surgery PLA General Hospital Department of Hepatobiliary Surgery Hainan Branch of PLA General Hospital Department of Anatomy Fourth Military Medical University Department of Hepatobiliary Surgery Graduate School of Medicine Kyoto University

BACKGROUND: Liver surgery has gone through the phases of wedge liver resection, regular resection of hepatic lobes, irregular and local resection, extracorporeal hepatectomy, hemi-extracorporeal hepatectomy and Da Vinci surgical system-assisted hepatectomy. Taking advantage of modern technologies, liver surgery is stepping into an age of precise liver resection. This review aimed to analyze the comprehensive application of modern technologies in precise liver resection. DATA SOURCE: PubMed search was carried out for English-language articles relevant to precise liver resection, liver anatomy, hepatic blood inflow blockage, parenchyma transection, and down-staging treatment. RESULTS: The 3D image system can imitate the liver operation procedures, conduct risk assessment, help to identify the operation feasibility and confirm the operation scheme. In addition, some techniques including puncture and injection of methylene blue into the target Glisson sheath help to precisely determine the resection. Alternative methods such as Pringle maneuver are helpful for hepatic blood inflow blockage in precise liver resection. Moreover, the use of exquisite equipment for liver parenchyma transection, such as cavitron ultrasonic surgical aspirator, ultrasonic scalpel, Ligasure and Tissue Link is also helpful to reduce hemorrhage in liver resection, or even operate exsanguinous liver resection without blocking hepatic blood flow. Furthermore, various down-staging therapies including transcatheter arterial chemoembolization and radio-frequency ablation were appropriate for unresectable cancer, which reverse the advanced tumor back to early phase by local or systemic treatment so that hepatectomy or liver transplantation is ***: Modern technologies mentioned in this paper are the key tool for achieving precise liver resection and can effectively lead to maximum preservation of anatomical structural integrity and functions of the remnant liver. In addition, large rand

关键词： precise liver resection anatomy parenchyma transection down-staging treatment

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Thermoelectric performance of(AgBiTe_(2))_(1-x)(SnTe)_(x) with stable cubic enabled by enhanced configurational entropy

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Rare Metals 2022年第12期41卷 4149-4155页

作者： Ting Zhao Li-Ze Yang Yun Zhou hui-Jun liao Zheng-Yong Huang Jian Li Xu Lu Xiao-Yuan Zhou Chongqing Key Laboratory of Soft Condensed Matter Physics and Smart Materials College of PhysicsChongqing UniversityChongqing 401331China College of Ocean Science and Engineering Shanghai Maritime UniversityShanghai 201306China State Key Laboratory of Power Transmission Equipment&System Security and New Technology Chongqing UniversityChongqing 400030China Analytical and Testing Center Chongqing UniversityChongqing 401331China

ABX_(2)(A=Ag,Na,Cu;B=Sb,Bi;X=S,Se,Te)(GroupsⅠ-Ⅴ-Ⅵ_(2))compounds,which are all characterized by the ultralow lattice thermal conductivity because of their strong lattice anharmonicity caused by lone-pair electrons,have aroused wide attention in thermoelectric *** practical application of thermoelectric devices usually requires both the compatible n-type and p-type materials ***,most ofⅠ-Ⅴ-Ⅵ_(2)compounds are intrinsic p-type semiconductors,lacking their n-type counterparts for ***,in this work,we increase the configuration entropy of AgBiTe_(2)by alloying SnTe,in order to stabilize the cubic phase at room *** further optimization of thermal and electrical performance,the thermoelectric performance could be improved simultaneously in both n-and p-type(AgBiTe_(2))_(1-x)(SnTe)_(x)(x=0.3,0.4)solid ***,p-type compound with the nominal composition of(AgBi_(0.99)Cd_(0.01)Te_(2))_(0.6)(SnTe)_(0.4)and n-type of(AgBiTe_(2))_(0.7)(SnTe)_(0.3)~Br 6%show the maximum zT of~0.33 and~0.21,at 381 and 423 K,respectively.

关键词： Configurational entropy Cubic phase Solid solutions Thermoelectrics

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Rac1 Signaling in Amygdala Astrocytes Regulates Fear Memory Acquisition and Retrieval

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Neuroscience Bulletin 2021年第7期37卷 947-958页

作者： Xiao-Cen Fan Chao-Nan Ma Jia-Chen Song Zhao-hui liao Nan Huang Xing Liu Lan Ma Department of Neurosurgery Huashan HospitalState Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain ScienceSchool of Basic Medical SciencesInstitutes of Brain ScienceFudan UniversityShanghai 200032China

The importance of astrocytes in behavior control is increasingly appreciated,but little is known about the effects of their dynamic activity in regulating learning and *** the present study,we constructed AAVs of photoactivatable and photoinactivatable Ras-related C3 botulinum toxin substrate 1(Rac1)under the mGFAP promoter,which enabled the manipulation of Rac1 activity in astrocytes by optical stimulation in free-moving *** found that both up-regulation and down-regulation of astrocytic Rac1 activity in the basolateral amygdala(BLA)attenuated memory acquisition in a fear conditioning mouse ***,neuronal activation in the BLA induced by memory acquisition was inhibited under both the up-and down-regulation of astrocytic Rac1 activity during *** terms of the impact on fear memory retrieval,we found both up-and down-regulation of BLA astrocytic Rac1 activity impaired memory retrieval of fear conditioning and memory retrieval-induced neuronal ***,the effect of astrocytic Rac1 on memory retrieval was *** results demonstrate that the normal activity of astrocytic Rac1 is necessary for the activation of neurons and memory *** activation and inactivation of astrocytic Rac1 activity in the BLA reduced the excitability of neurons,and thereby impaired fear memory acquisition and retrieval.

关键词： Rac1 Astrocyte Neuron BLA Fear memory

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翁源兰花气象灾害气候特征分析及防御

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陕西气象 2024年第4期 67-71页

作者：颜金廖慧娟邓小良甘锦蕾罗宇翁源县气象局广东翁源512600 翁源县突发事件预警信息发布中心广东翁源512600 始兴县气象局广东始兴512500

利用1978—2022年翁源县国家基本气象站逐日资料,针对低温霜冻、暴雨、低温连阴雨和高温热害,从气候条件分析这4种农业气象灾害的变化趋势和发生规律,及其对翁源兰花种植的影响和应对措施。结果表明:近45 a翁源低温霜冻和低温连阴雨日... 详细信息

利用1978—2022年翁源县国家基本气象站逐日资料,针对低温霜冻、暴雨、低温连阴雨和高温热害,从气候条件分析这4种农业气象灾害的变化趋势和发生规律,及其对翁源兰花种植的影响和应对措施。结果表明:近45 a翁源低温霜冻和低温连阴雨日数呈显著减少趋势,冬季兰花种植仍有霜冻风险,低温连阴雨日数减少对兰花生长发育有利;高温热害呈显著增多趋势,兰花种植需增加高温防护措施的投入;汛期暴雨天气发生频率较高,大暴雨也趋于增多,兰花种植应特别注意防洪防涝。

关键词：气象灾害兰花霜冻高温热害广东翁源

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Self-assembly of Gold Nanoparticle Chains between Nanoelectrodes

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Chinese Chemical Letters 2006年第6期17卷 845-847页

作者： Ning GU Jian hui liao Lan HUANG Zhi Rui GUO Wei YU Li Na XU Jing WANG Key Laboratory of Molecular and Biomolecular Electronics Department of Biological Science and Medical Engineering Southeast University Nanjing 210096

A novel strategy has been developed for construction of nanoparticle chains between nanoelectrodes with bifunctional molecules by taking advantage of linear aggregation of colloidal particles in organis solvents. As confirmed by scanning electron microscopy （SEM）,an individual nanoparticle chain bridged the electrode pair. The present approach makes this technique to be cheap and may be applicable in microelectronic industry.

关键词： Self-assembly nanoparticle chain nanoelectrode.

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