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Unsupervised full-color cellular image reconstruction through disordered optical fiber

Light(Science & Applications) 2023年第6期12卷 1091-1102页

作者： Xiaowen Hu Jian Zhao Jose Enrique Antonio-Lopez Rodrigo Amezcua correa Axel Schülzgen CREOL The College of Optics and PhotonicsUniversity of Central FloridaOrlandoFL 32816USA The Picower Institute for Learning and Memory Massachusetts Institute of TechnologyCambridgeMA 02139USA

Recent years have witnessed the tremendous development of fusing fiber-optic imaging with supervised deep learning to enable high-quality imaging of hard-to-reach ***,the supervised deep learning method imposes strict constraints on fiber-optic imaging systems,where the input objects and the fiber outputs have to be collected in *** unleash the full potential of fiber-optic imaging,unsupervised image reconstruction is in ***,neither optical fiber bundles nor multimode fibers can achieve a point-to-point transmission of the object with a high sampling density,as is a prerequisite for unsupervised image *** recently proposed disordered fibers offer a new solution based on the transverse Anderson ***,we demonstrate unsupervised full-color imaging with a cellular resolution through a meter-long disordered fiber in both transmission and reflection *** unsupervised image reconstruction consists of two *** the first stage,we perform a pixel-wise standardization on the fiber outputs using the statistics of the *** the second stage,we recover the fine details of the reconstructions through a generative adversarial *** image reconstruction does not need paired images,enabling a much more flexible calibration under various *** new solution achieves full-color high-fidelity cell imaging within a working distance of at least 4 mm by only collecting the fiber outputs after an initial *** imaging robustness is also demonstrated when the disordered fiber is bent with a central angle of 60°.Moreover,the cross-domain generality on unseen objects is shown to be enhanced with a diversified object set.

关键词： fiber optical image

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Magnetic-gateable valley exciton emission

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npj Computational Materials 2020年第1期6卷 915-923页

作者： Helena Bragança Hao Zeng Alexandre Cavalheiro Dias Jorge Huamani correa Fanyao Qu Instituto de Física Universidade de BrasíliaBrasília-DF 70919-970Brazil departamento de Física Universidade Federal de Ouro PretoOuro PretoMinas Gerais 35400-000Brazil department of Physics University at Buffalothe State University of New YorkBuffaloNY 14260USA

The use of valley excitonic states of transition metal dichalcogenides to store and manipulate information is hampered by fast carrier recombination and short valley *** propose theoretically a scheme to overcome such an obstacle,by applying a tilted exchange field through the magnetic proximity effect on monolayer MoS_(2).While the in-plane component of the exchange field brightens the dark exciton by spin mixing,the out-of-plane field can effectively gate the emission with an ON/OFF ratio of ***,the brightening is valley selective,leading to nearly 100% valley and spin polarization at room *** resulting strongly gateable dark-exciton emission with long lifetime and near unity valley polarization makes it convenient to manipulate the valley degree of freedom,which may offer new paradigm for information processing and transmission.

关键词： temperature overcome applying

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Security-constrained model for integrated power and natural-gas system

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Journal of Modern Power Systems and Clean Energy 2017年第3期5卷 326-336页

作者： Carlos M.correa-POSADA Pedro SáNCHEZ-MARTíN Sara LUMBRERAS XM Compania de Expertos en MercadosMedellı´nColombia Technological Research Institute(IIT) ICAI School of EngineeringComillas Pontifical UniversityMadridSpain

One of the main factors impacting the reliability of energy systems nowadays is the growing interdependence between electricity and gas networks due to the increase in the installation of gas-fired units. Securityconstrained unit commitment(SCUC) models are used to economically schedule generating units without compromising the system reliability. This paper proposes a novel SCUC formulation that includes dynamic gas constraints,such as the line pack, and transmission contingencies in power and gas networks for studying the integrated system reliability. A Benders’ decomposition with linear programming techniques is developed to be able to study large systems. By including dynamic gas constraints into the SCUC, the proposed model accounts for the flexibility and reliability that power systems require from gas systems in the short term. Case studies of different size and complexity are employed to illustrate how the reliability of one system is affected by the reliability of the other. These experiments show how both systems operate in a secure way(by including contingencies) increases operating costs by approximately 9% and also show how these costs can vary by 24% depending on the line pack scheduling.

关键词： Benders’decomposition Natural gas Reliability Security-constrained unit commitment

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A robust methodology for the quantitative assessmentof the rat jawbone microstructure

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International Journal of Oral Science 2017年第2期9卷 87-94页

作者： Marissa Chatterjee Fernanda Faot Cassia correa Joke Duyck Ignace Naert Katleen Vandamme department of Oral Health Sciences&dental Clinic Biomaterials--BlOMATKU Leuven&University Hospitals LeuvenLeuvenBelgium Federal University of Pelotas--School of dentistry PelotasBrazil University of Campinas--UNICAMP/Piracicaba dental School PiracicabaBrazil

Micro-computed tomography can be applied for the assessment of the micro-architectural characteristics of the cortical and trabecular bones in either physiological or disease conditions. However, reports often lack a detailed description of the methodological steps used to analyse these images, such as the volumes of interest, the algorithms used for image filtration, the approach used for image segmentation, and the bone parameters quantified, thereby making it difficult to compare or reproduce the studies. This study addresses this critical need and aims to provide standardized assessment and consistent parameter reporting related to quantitative jawbone image analysis. Various regions of the rat jawbones were screened for their potential for standardized micro-computed tomography analysis. Furthermore, the volumes of interest that were anticipated to be most susceptible to bone structural changes in response to experimental interventions were defined. In the mandible, two volumes of interest were selected, namely, the condyle and the trabecular bone surrounding the three molars. In the maxilla, the maxillary tuberosity region and the inter-radicular septum of the second molar were considered as volumes of interest. The presented protocol provides a standardized and reproducible methodology for the analysis of relevant jawbone volumes of interest and is intended to ensure global, accurate, and consistent reporting of its morphometry. Furthermore, the proposed methodology has potential, as a variety of rodent animal models would benefit from its implementation.

关键词： bone microarchitecture jawbone methodology micro-computed tomography rat

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Influence of the Freshwater Discharge on the Hydrodynamics of Patos Lagoon, Brazil

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International Journal of Geosciences 2014年第9期5卷 925-942页

作者： Gustavo Pessoa de Barros Wiliam correa Marques Eduardo de Paula Kirinus Institute of Mathematics Statistics and Physics Federal University of Rio Grande Rio Grande Brazil Institute of Oceanography Federal University of Rio Grande Rio Grande Brazil

Patos Lagoon is a very dynamic environment presenting hydrodynamic fluctuations from synoptic to decadal timescales. Thus, understanding the processes that determine the long term variability is fundamental for the correct coastal planning and management of this region. The main objective of this study is to understand how the freshwater discharge of the main tributaries controls the estuarine hydrodynamics of the Patos Lagoon, when considering long term timescales. Two numerical simulations were carried out using the TELEMAC3D numerical model, the former using freshwater discharge from 1940 to 1973 year (simulation A), and the second simulation using data between 1974 and 2006 year (simulation B). These two periods were selected because before (after) 1973 year, the annual mean freshwater discharge was lower (higher) than the mean value for the whole period (1080 m3/s). The navigational channel discharge, water level, salinity and current velocity differences between both simulations were analyzed. Ebb conditions prevailed over flood conditions for both simulations, but simulation B presented a higher volume of freshwater exported through the coastal zone. Water level differences demonstrated higher values (0.08 meters) close to the Guaiba River, which is the main tributary of the study region, and lower values were observed near to the Patos Lagoon mouth (0 meters). The most significant differences in the mean bottom and surface salinity were observed in the central zone of the estuary and at the Barra Breakwaters. Simulation A presented higher saline intrusion due to lower freshwater discharge, while simulation B showed an increase in the coastal plume intensity, caused by the higher freshwater discharge. The hydrodynamical simulations demonstrated with precision that the freshwater discharge intensity determine the vertical stratification of the estuary.

关键词： Estuarine Hydrodynamics Freshwater Discharge Hydrodynamical Modeling

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Association between the CYBA and NOX4 genes of NADPH oxidase and its relationship with metabolic syndrome in non-alcoholic fatty liver disease in Brazilian population

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Hepatobiliary & Pancreatic Diseases International 2018年第4期17卷 330-335页

作者： Fabiola Rabelo Jose Tadeu Stefano Ana Mercedes Cavaleiro Rodrigo Vieira Costa Lima Daniel Ferraz de Campos Mazo Flair Jose Carrilho Maria Lúcia correa-Giannellac Claudia P.Oliveiraa departamento de Gastroenterologia Faculdade de Medicina FMUSPUniversidade de Sao PauloSao PauloSPBrazil Hospital das Clinicas HCFMUSP Departamento de GastroenterologiaLIM07Faculdade de MedicinaUniversidade de Sao PauloSao PauloSPBrazil Laboratório de Carboidratos e Radioimunensaio LIM18Hospital das Clinicas HCFMUSP(LIM07)Faculdade de MedicinaUniversidade de Sao PauloSao PauloBrazil Programa de Pos-Graduacao em Medicina Universidade Nove de Julho(UNINOVE)Sao PauloBrazil

Background: Oxidative stress has been implicated in the progression of severe forms of non-alcoholic fatty liver disease(NAFLD). NADPH oxidase produces reactive oxygen species. In the present study, we investigated for the first time two single nucleotide polymorphisms(SNPs) in the regulatory region of genes encoding NADPH oxidase 4(NOX4) and p22 phox(CYBA) in ***: A total of 207 biopsy-proven NAFLD patients [simple steatosis(n = 27); nonalcoholic steatohepatitis(NASH)(n = 180)] were evaluated. Genomic DNA was extracted from peripheral blood cells, and polymorphisms in CYBA(unregistered) and NOX4(rs3017887) were determined by direct sequencing of ***: Associations of CYBA-675 T/A with high-density lipoprotein(HDL)(TT vs TA vs AA; P des(TGL)(TT vs XA; P degrees of fibrosis occurred in patients diagnosed with type 2 diabetes mellitus(66.9% vs 37.5%, P degrees of fibrosis in NAFLD patients.

关键词： Non-alcoholic fatty liver disease Nonalcoholic steatohepatitis Genetic polymorphism Metabolic syndrome

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The Contribution of Waves in Mixing Processes of the Patos Lagoon Plume

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International Journal of Geosciences 2012年第5期3卷 1019-1026页

作者： Eduardo de Paula Kirinus Wiliam correa Marques Julliet correa da Costa Elisa Helena Leao Fernandes Instituto de Matematica Estatistica e Fisica Universidade Federal do Rio GrandeRio Grande do SulBrazil Instituto de Oceanografia Universidade Federal do Rio GrandeRio Grande do SulBrazil

The analysis of wave effects above salinity is important in order to define mixing processes and their potential to change density gradients, since action in the region of the Patos Lagoon plume is highly dynamic. This paper aims to evaluate the influence of waves on the mixing pattern of the adjacent continental shelf. Constantly marked by tides and circulation variations, changing from flood to ebb tide, salinity stands as a major parameter for analysis. The study is based on hydrodynamic numerical modeling experiments using the TELEMAC3D model and waves generated by the wind using the TOMAWAC coupled model. The comparison between the situations considering the waves generated by the wind and without waves was made through time series analysis, stratification series, transversal cross sections, longitudinal cross sections, salinity mean fields and diagrams by Richardson and Brünt-V?is?l?s frequency parameters. With the cross sections analysis, the mixing effect generated by the waves was observed, demonstrating clearly that the waves were capable of raising the superficial salinity in regions far from the Patos Lagoon entrance, while at the entrance, the wave effects enhanced the mixing on the deepest layers, decreasing the saline intrusion and expanding the plume more radially on the surface. The space-temporal diagrams were effective to demonstrate the modulation effect of the waves over the salt mixing of saline waters, revealing that wave effects decrease the stratification as well as the Brünt-V?is?l?s frequency and increase the period of buoyancy, due to the mixing increase.

关键词： Vertical Mixing Tridimensional Numerical Modeling Stratification

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Andean orogenic signature in the Quaternary sandy barriers of Southernmost Brazilian Passive Margin – Paradigm as a source area

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Geoscience Frontiers 2021年第4期12卷 61-70页

作者： Farid Chemale Junior Ernesto Luiz correa Lavina Julierme Justin Carassai Tiago Jonatan Girelli Cristiano Lana Programa de Pós Graduação em Geologia Universidade do Vale do Rio dos Sinos93022-220São LeopoldoRSBrazil departamento de Geologia Universidade Federal do Ouro Preto35400-000Morro do CruzeiroOuro PretoMGBrazil

Multiple source provenance of sediments and submarine fan formation are herein investigated based on Quaternary sandy barriers of the Brazilian Southernmost Coastal ***-ICP-MS dating on 1625 detrital zircons from marine and aeolian facies sands of four successive lagoon-barrier systems are *** characterization of Archean to Pleistocene zircons into a younger Andean(22±4 Ma to 1±1 Ma,48 from 1625),Mesozoic to Paleozoic,and Mesoproterozoic(479 from 1622)populations suggest that the main feeding of sediments to the coastal plain occurred through the La Plata River drainage *** significant contribution of sediments is transported from the mouth of La Plata River northward by longshore circulation(littoral drift).Minor contributions are also recognized as.a farther source associatedwith the Patagonia drainage and nearby source related to the Uruguay/Rio Grande do Sul Shield and the ParanáBasin,drained by the Camaquãand Jacuí*** latter one is recognized by the contribution fromNeoproterozoic to Early Paleozoic,and some Paleoproterozoic and Archean zircon *** definition of the sources of clastic sediments allows inferences about the origination of Rio Grande Fan where both the cold Falkland and the warm Brazil currents played a major role.

关键词： U–Pb zircon Coastal plain Andean provenance Source to sink process Rio Grande Fan Ocean Atlantic

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Atypical chemokine receptor CCRL2 is overexpressed in prostate cancer cells

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The Journal of Biomedical Research 2019年第1期33卷 17-23页

作者： Niradiz Reyes Ines Benedetti Juan Rebollo Oscar correa Jan Geliebter department of Basic Sciences School of MedicineUniversity of Cartagena Research Group of Genetics and Molecular Biology New York Medical College Research Group of Histopathology New York Medical College School of Medicine Department of Microbiology and Immunology New York Medical College

Atypical chemokine receptors have recently emerged as important molecular players in health and diseases; they affect chemokine availability and function and impact a multitude of pathophysiological events, including the tumorigenesis process. This family of atypical receptors comprises five members: ACKR1/DARC, ACKR2/D6,ACKR3/CXCR7, ACKR4/CCRL1, and ACKR5/CCRL2. This work evaluated the differential expression of these receptors in prostate cancer using quantitative PCR. Further evaluation of CCRL2 at the protein level confirmed its overexpression in a metastatic cell line and in malignant prostatic tissues from patients. CCRL2, a presumed member of the atypical chemokine receptor family, plays a key role in lung dendritic cell trafficking to peripheral lymph *** studies have reported the expression of CCRL2 in different human cancer cell lines and tissues. However, its function and expression in prostate cancer has not been previously addressed.

关键词： chemokine receptor prostatic neoplasms CCRL2 receptor real-time polymerase chain reaction tissue array analysis

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Photodynamic therapy vs radiofrequency ablation for Barrett's dysplasia: Efficacy,safety and cost-comparison

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World Journal of Gastroenterology 2013年第41期19卷 7106-7113页

作者： Atilla Ertan Irum Zaheer Arlene M correa Nirav Thosani Shanda H Blackmon Ertan Digestive Disease Center Memorial Hermann HospitalTexas Medical CenterHoustonTX 77030United States Division of Gastroenterology Hepatology and NutritionThe University of Texas Health Science Center at HoustonHoustonTX 77030United States Division of Gastroenterology The Methodist HospitalHoustonTX 77030United States Division of Thoracic and Cardiovascular Surgery The University of Texas MD Anderson Cancer CenterHoustonTX 77030United States department of Surgery The Methodist HospitalHoustonTX 77030United States

AIM:To compare effectiveness,safety,and cost of photodynamic therapy(PDT)and radiofrequency ablation(RFA)in treatment of Barrett’s dysplasia(BD).METHODS:Consecutive case series of patients undergoing either PDT or RFA treatment at single center by a single investigator were ***-three patients with high-grade dysplasia(HGD)had treatment with porfimer sodium photosensitzer and 630 nm laser(130 J/cm),with maximum of 3 treatment ***-three patients with BD(47 with low-grade dysplasia-LGD,6 with HGD)had step-wise circumferential and focal ablation using the HALO system with maximum of 4 treatment *** groups received proton pump inhibitors twice *** biopsies were acquired at 2 and 12 mo after enrollment,with 4-quadrant biopsies every 1 cm of the original BE extent.A complete histological resolution response of BD(CR-D)was defined as all biopsies at the last endoscopy session negative for ***’s exact test was used to assess differences between the two study groups for primary *** all outcomes,a two-sided P value of less than 0.05 was considered to indicate statistical ***:Thirty(91%)PDT patients and 39(74%)RFA were men(P=0.05).The mean age was 70.7±12.2 and 65.4±12.7(P=0.10)year and mean length of BE was 5.4±3.2 cm and 5.7±3.2 cm(P=0.53)for PDT and RFA patients,*** CR-D was(18/33)54.5%with PDT vs(47/53)88.7%with RFA(P=0.001).One patient with PDT had an esophageal perforation and was managed with non-surgical measures and no perforation was seen with *** was five times more costly than RFA at our *** two groups were not randomized and had different BD grading are the limitations of the ***:In our experience,RFA had higher rate of CR-D without any serious adverse events and was less costly than PDT for endoscopic treatment of BD.

关键词： Barrett’s esophagus Dysplasia Photodynamic therapy Radiofrequency ablation Cost comparison

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