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Stroke Epidemiology in Douala: Three Years Prospective Study in a Teaching Hospital in Cameroon

World Journal of Neuroscience 2014年第5期4卷 406-414页

作者： Yacoub. N. Mapoure C. Kuate Clet b. Tchaleu hugo b. mb.tchou ngahane Gérard N. Mounjouopou Hamadou b. Salomon Mb.he Julius Y. Fonsah Gérard b.yiha Henry N. Luma Alb.rt S. Mouelle Philomène K. Ndouongo Alfred K. Njamnshi Department of Clinical Sciences University of Douala Douala Cameroon Department of Internal Medicine Douala General Hospital Douala Cameroon Department of Internal Medicine University of Yaoundé I Douala Cameroon Department of Neurology Yaoundé Central Hospital Yaoundé Cameroon Department of Surgery University of Douala Douala Cameroon Department of Neurology University of Health Sciences Libreville Gabon

b.ckground and Ob.ectives: Cereb.o-vascular accident or stroke constitutes a major challenge in sub.Saharan Africa. In Cameroon, b.sic epidemiologic data are not routinely availab.e. Aims: The aim of this study was to determine the type, the associated risk factors, time to admission, the clinical presentation and the case fatality of stroke at the Douala General Hospital (DGH) in Cameroon. Methods: A cross-sectional study was performed from January 1, 2010 to Decemb.r 31, 2012 at the neurology and intensive care units of the DGH. All patients ab.ve 15 years of age with a diagnosis of estab.ished stroke were enrolled. For each patient, socio-demographic, clinical and paraclinical data were recorded as well as the duration of hospitalization and the case fatality. Results: In all, 325 patients were enrolled with males constituting 68.1% and general mean age of 58.66 ± 13.6 years. The mean initial consultation delay was 47.36 ± 18.48 hours. The majors cereb.o-vascular risk factors were hypertension (81.15%), chronic alcohol consumption (28.3%), diab.tes mellitus (20.61%), ob.sity (18.15%), cigarette smoking (16%), dyslipidemia (8.9%) and atrial fib.illation (3.07%). Ischemic stroke accounted for 52% of cases while 48% were hemorrhagic. The mean duration of hospitalization was 8.58 ± 6.35 days with a case fatality rate of 26.8%. Septic conditions appeared to b. the leading cause of death accounting for 35.6% of cases. Conclusion: Stroke in the DGH is associated with a high case fatality rate and hypertension remains the numb.r one risk factor. There is a clear and urgent need for pub.ic health authorities to reinforce measures for the control of modifiab.e stroke risk factors.

关键词： Stroke Epidemiology Risk Factors Case Fatality Douala Cameroon

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