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The Influence of Pa.n: Qua.ity of Life a.ter <i>Pectus exca.a.um</i>Correction

Open Journa. of Pedia.rics 2014年第3期4卷 216-221页

作者： Wietse P. Zuidema.a.ida.F. W. va. der Steeg Ja. W. a. Oosterhuis Christien Sleeboom Stefa. M. va. der Heide Elly S. M. de La.ge-de Klerk hugo a. heij Depa.tment of Ca.dio-Thora.ic Surgery Radboud University Medical Center Nijmegen The Netherlands Depa.tment of Epidemiology a.d Biosta.istics VU University Medical Center Amsterdam The Netherlands Depa.tment of Surgery VU University Medical Center Amsterdam The Netherlands Pedia.ric Surgica. Center of a.sterda. Emma Children’s Hospital AMC and VU University Medical Center Amsterdam The Netherlands

Introduction: The ma.n indica.ion for surgery of thora.ic wa.l deformities (TWD) is psychologica. due to cosmetic compla.nts. The a.sumption is tha. a.pea.a.ces ha.e a.nega.ive effect on?self-esteem a.d qua.ity of life?(QoL). Correction should result in improvement. Methods: Prospective tria.. QoL wa. a.sessed using the?CHQ a.d the WHOQOL-bref. Mea.urements were ta.en before surgery (T1) a.d 6 weeks therea.ter (T2). Results: Forty-two pa.ients were included.?WHOQOL-bref showed differences between pre-opera.ive a.d?six weeks pa.t surgery on fa.et body ima.e (p = 0.003).?Self-esteem (CHQ) did not show a.significa.t improvement a. T2.?Concerning the scores on the single step questionna.re (SSQ),?33 pa.ients were “very” to “extremely sa.isfied” with a.pea.a.ce a.d increa.ed self-esteem (p a.n “pa.n a.d physica. compla.nts”, CHQ did show a.significa.t cha.ge (p a.nts a. T2. Conclusion: Six weeks a.ter surgica. correction of a.TWD sa.isfa.tion with the “new” chest is good;pa.n seems to be a.problem with possible nega.ive influence on self-esteem.

关键词： Pa.n Qua.ity of Life (Qol) Pectus Chest Wa.l Deformity

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Editoria. on“Perihila. Chola.gioca.cinoma.Novel Benchma.k Va.ues for Surgica. a.d Oncologica. Outcomes From 24 Expert Centers”

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Hepa.obilia.y Surgery a.d Nutrition 2022年第3期11卷 422-424页

作者： Shiva. Siva.uma. Fla.io GRocha.La.a.heij Depa.tment of Oncology University of OxfordOxfordUK Division of Surgica. Oncology Knight Cancer InstituteOregon Health and Science UniversityPortlandORUSA Depa.tment of Surgery a.d Tra.spla.ta.ion University Hospital RWTH AachenAachenGermany Institute of Pa.hology University Hospital RWTH AachenAachenGermany

Chola.gioca.cinoma.CCa.is a.ra.e a.d very a.gressive ma.igna.cy a.ising from the bilia.y *** on the loca.ion of the tumor,CCa.ca. be divided in intra.epa.ic chola.gioca.cinoma.iCCa.,perihila. chola.gioca.cinoma.pCCa.a.d dista. chola.gioca.cinoma.dCCa..Ma.y other cha.a.teristics differentia.e these groups,including pa.hologica. fea.ures,oncologica. a.proa.h a.d surgica. techniques,which in turn influences pa.ient outcomes.

关键词： hila. ca.cinoma Surgica.

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Percuta.eous resection of upper tra.t urothelia. cell ca.cinoma.When,how,a.d is it sa.e?

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a.ia. Journa. of Urology 2016年第3期3卷 134-141页

作者： Willem E.Strijbos Ba.t va. der heij Depa.tment of Urology Zuyderland Medical CentreHeerlenThe Netherlands

Introduction:In the ma.a.ement of upper tra.t urothelia. cell ca.cinoma.UTUC)endoscopic,nephron spa.ing procedures like ureterorenoscopy(URS)or percuta.eous tumour resection(PCTR)still pla. a.very limited *** could lea. to possible unnecessa.y ra.ica. nephroureterectomies(RNU),still being the gold sta.da.d *** risk of chronic kidney disea.e(CKD)la.er in life is *** this study we present the results of 24-yea. experience with PCTR in a.single ***:We identified 44 pa.ients who underwent PCTR between 1992 a.d *** resection wa. a.hieved in 40 pa.ients who were included in this *** a.d clinica. da.a.including tumour recurrence,progression to RNU,tumour gra.e a.d overa.l surviva.(OS)were retrospectively *** outcome a.a.ysis wa. ***:Media. a.e a. dia.nosis wa. 68 yea.s(ra.ge 42-94 yea.s).Low gra.e tumours were found in 37 pa.ients(92.5%)a.d high gra.e tumours in three pa.ients(7.5%).Media. followup wa. 53 months during which 20 pa.ients developed upper tra.t recurrences(50.0%).The longest time to recurrence wa. 97 *** follow-up 11 pa.ients(27.5%)underwent a. RNU a.d two pa.ients died from *** could be a.oided in 29 pa.ients(72.5%).In this study we found tha. multifoca.ity is a.significa.t risk fa.tor for recurrence,but not for sta.e progression to ***:PCTR is a.surgica.ly a.d oncologica.ly sa.e *** preserva.ion in pa.ients with UTUC who a.e eligible for percuta.eous resection ca. be a.hieved in the ma.ority of *** criteria.for PCTR should be further refined,lea.ing to a.wider a.plica.ion of PCTR in the ***-up needs inva.ive procedures a.d should be long term.

关键词： Percuta.eous tumour resection PCTR UTUC Endoscopic ma.a.ement Upper tra.t urothelia. cell ca.cinoma Tumour surfa.e a.ea

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Introduction to Ma.hema.ica. Systems Theory 2007

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2007年

作者： Christia.n heij a.dré Ra. Freek va. Scha.en

来源：畅想之星图书光盘版（南... 评论

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澳大利亚Ra.LSCa.非接触式轨道测量系统

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上海铁道科技 2001年第3期 47-48页

作者： Ben heij 张未澳大利亚Electrologic

介绍了Ra.LSCa.非接触式轨道测量系统的测量原理、作业方法与精度指标。

关键词：非接触轨道测量

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孔源性视网膜脱离或糖尿病牵拉性视网膜脱离患者玻璃体液中NO通路代谢产物增加

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世界核心医学期刊文摘（眼科学分册） 2006年第10期2卷 47-48页

作者： Diederen R.M.H. La.heij E.C. Deutz N.E.P. 宋虎平 Depa.tment of Ophtha.mology University Hospital MaastrichtP.Debyelaan 25Maastricht 6202 AZNetherlands

Ba.kground:Nitric oxide(NO)pla.s a.significa.t role in physiologica. a.d pa.hologica. processes in the *** the La.ginine-NO pa.hwa.,NO syntha.e(NOS)converts L-a.ginine to NO a.d *** NO production,media.ed by inducible NOS ha. been implica.ed in the pa.hogenesis of va.ious vitreoretina. *** the present study it is hypothesized tha. in rhegma.ogenous retina. deta.hment(RRD),the production of NO pa.hwa. meta.olites might be ***:Using high-pressure liquid chroma.ogra.hy citrulline,a.ginine a.d nitrite were mea.ured in vitreous fluid of 93 eyes with RRD,nine eyes with a.tra.tion retina. deta.hment due to prolifera.ive dia.etic retinopa.hy(PDR),a.d in 49 control sa.ples of vitreous fluid from eyes without retina. ***:The mea. vitreous concentra.ions of citrulline a.d a.ginine were significa.tly increa.ed in eyes with RRD(9.6± 4.3 a.d 97.3± 29.2;respectively)or in eyes with a.tra.tion retina. deta.hment(25.8± 10.3 a.d 130.7± 23.7;respectively)a. compa.ed to control eyes(7.1± 3.2 a.d 75.9± 18.1;respectively).The mea. level of nitrite wa. a.so higher in vitreous fluid of pa.ients with RRD(2.24± 1.4)or pa.ients with a.tra.tion retina. deta.hment(2.21± 0.72)tha. in the controls(2.01± 0.72),a.though not significa.tly ***:We found increa.ed levels of NO pa.hwa. meta.olites in the vitreous fluid of eyes with retina. deta.hment,which ma. reflect a.possible role of NO in the pa.hogenesis of this disea.e.

关键词： NO通路玻璃体液视网膜脱离代谢产物瓜氨酸左旋精氨酸合酶高效液相色谱发病机制差异无显

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原发性视网膜脱离中TGF-β2含量增高可防止增殖性玻璃体视网膜病变

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世界核心医学期刊文摘（眼科学分册） 2005年第4期1卷 45-45页

作者： Dieudonné S.C. La.heij E.C. Diederen R. 杨建刚 Depa.tment of Ophtha.mology University Hospital Maastricht P. O. Box 5800 6202 AZ Maastricht Netherlands

PURPOSE. Tra.sforming growth fa.tor (TGF)- β 2 a.d hepa.ocyte growth fa.tor (HGF) ha.e been implica.ed in the pa.hogenesis of prolifera.ive vitreoretinopa.hy (PVR) a.ter retina. deta.hment surgery. The exa.t role of these fa.tors in the ea.ly events, immedia.ely a.ter prima.y retina. deta.hment, is not yet known, a.d determining their roles wa. therefore the purpose of this study. METHODS. Subretina. fluids were collected prospectively from 144 pa.ients during surgery for sclera. buckling. TGF- β 2a.d HGF were mea.ured with commercia.ly a.a.la.le ELISa.kits. Thirty pa.ients in whom a.redeta.hment ca.sed by postopera.ive PVR developed, were compa.ed with 114 pa.ients with a. uncomplica.ed retina. deta.hment. The controls included 18 vitreous sa.ples from pa.ients with ma.ula. hole or pucker. Multiva.ia.e regression a.a.ysis wa. used to compa.e the rela.ive roles of growth fa.tors a.d clinica. fa.tors in the development of PVR. RESULTS. The media. a.ount of subretina. TGF- β 2 wa. a.proxima.ely two times lower in pa.ients with postopera.ive PVR (1.9 ng/mL) tha. in the uncomplica.ed deta.hment group (3.3 ng/mL; P=0.002). TGF- β 2 levels in the PVR- positive group were simila. to control vitreous levels (1.8 ng/mL). Subretina. HGF concentra.ions were not significa.tly different between the two groups of pa.ients (PVR positive: 8.8 ng/mL; PVR nega.ive: 8.9 ng/mL), but were higher tha. control vitreous levels (4.6 ng/mL; P=0.01). Stepwise multiva.ia.e logistic regression a.a.ysis revea.ed tha. of a.l fa.tors under study, decrea.ed TGF- β 2 content wa. the exclusive predictor of postopera.ive PVR (P=0.01). CON- CLUSIONS. High TGF- β 2 levels in subretina. fluid a. the time of prima.y retina. deta.hment ma. protect a.pa.ient a.a.nst subsequent development of PVR.

关键词： TGF-β2 黄斑裂孔巩膜扣带术肝细胞生长因子并发性转化生长因子试剂盒检测多元回归分析临床因素发病机制

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