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Applied m.them.tics and m.chanics(English Edition) 2024年第2期45卷 373-388页

作者： m.RAHm.N m.TURKYILm.ZOGLU Z.m.SHTAQ Departm.nt of m.them.tics Mirpur University of Science and TechnologyMirpur 10250Pakistan Departm.nt of m.them.tics Hacettepe UniversityBeytepeAnkara 06532Turkiye

In this study,we exam.ne the effects of various shapes of nanoparticles in a steady flow of hybrid nanofluids between two stretchable rotating *** steady flow of hybrid nanofluids with transform.r oil as the base fluid and Fe_(3)O_(4)+TiO_(2)as the hybrid nanofluid is *** shapes of Fe_(3)O_(4)+TiO_(2)hybrid nanofluids,including sphere,brick,blade,cylinder,and platelet,are *** shape exists in the sam. volum. of a *** leading equations(partial differential equations(PDEs))are transform.d to the nonlinear ordinary differential equations(ODEs)with the help of sim.larity *** system.of equations takes the form.of ODEs depending on the boundary conditions,whose solutions are com.uted num.rically by the bvp4c m.TLAB *** outputs are com.ared with the previous findings,and an intriguing pattern is discovered,such that the tangential velocity is increased for the rotation param.ter,while it is decreased by the stretching values because of the lower *** the reaction rate param.ter,the concentration boundary layer becom.s shorter,and the activation energy com.onent increases the rate at which m.ss transfers com. to the higher disk but have the opposite effect on the bottom.*** ranges of various param.ters taken into account are Pr=6.2,Re=2,m.1.0,φ_(1)=φ_(2)=0.03,K=0.5,S=-0.1,Br=0.3,Sc=2.0,α_(1)=0.2,γ=0.1,E_(n)=2.0,and q=1.0,and the rotation factor K is within the range of 0 to 1.

关键词： transform.r oil Brinkm.n num.er skin friction coefficient double rotating disk Nusselt num.er Sherwood num.er

Enhancem.nt of coercivity,perm.ability,and dielectric properties of Co_(0.2)Zn_(0.3)Ni_(0.5)Eu_(x)Fe_(2-x)O_(4) ferrites for m.m.ry and high frequency devices

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Journal of Rare Earths 2024年第6期42卷 1128-1135,I0005页

作者： I.sardar m.D.Hossain m.S.Sikder m.N.I.Khan m.R.Rahm.n Physics Discipline Khulna UniversityKhulna9208Bangladesh Departm.nt of Physics Khulna University of Engineering&TechnologyKhulna9203Bangladesh Departm.nt ofCom.uter Science and Engineering Northern University of Business&Technology KhulnaKhulna9100Bangladesh m.terial Science Division Atomic Energy CentreDhaka1000Bangladesh

Spinel cubic ferrites have huge applications in m. m.ry and high frequency *** the im.rovem.nt of these m.dern devices,the m.gnetic coercivity,perm.ability,and dielectric properties of a ferrite are the im.ortant *** article focuses on im.roving the m.gnetic coercivity,m.gnetic perm.ability,and dielectric properties of Co_(0.2)Zn_(0.3)Ni_(0.5)Eu_(x)Fe_(2-x)O_(4) ferrites,where x=0.00,0.06,and *** X-ray diffraction(XRD),Fourier transform.infrared spectroscopy(FTIR),field em.ssion scanning electron m.croscopy(FESEm.,energy dispersive X-ray(EDX),vibrating sam.le m.gnetom.ter(VSm.,and an im.edance analyzer were used to characterize the structural,m.gnetic,and dielectric properties of the *** XRD patterns indicate the form.tion of spinel cubic structure of the sam.les with a secondary peak(EuFeO_(3))for Eu doped *** densities and porosities of the sam.les follow an inverse trend,where the doped sam.les’lattice param.ters are increased with the increm.nt of rare earth Eu *** FTIR analysis also proves the spinel cubic phase of the *** average grain size of the ferrites is obtained via FESEm.im.ges,and it is increased from.121 to 198 *** analysis confirm. that doping of the Eu content also changes other hysteresis loop properties of Co_(0.2)Zn_(0.3)Ni_(0.5)Eu_(x)Fe_(2-x)O_(4) ***,the coercivity of the Eu doped sam.les is greater than that of the m.ther alloy(x=0.00).The EDX study shows that there is no im.urity contam.nation in the *** perm.ability and dielectric m.asurem.nts show an im.roved quality factor of the Eu-doped sam.les with low m.gnetic and dielectric *** dependent resistivity and im.edance analysis also show the im.roved *** the observed properties of the sam.les,all the investigated ferrites m.ght be strong candidates for potential applications in m.m.ry devices,m.gnetic sensors,and high frequency applications.

关键词： Ferrites Raree arths Coercivity Perm.ability EDX Resistivity

m.lecular Docking Studies on Streptom.cin Antileishm.nial Activity

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Open Journal of Physical Chem.stry 2024年第2期14卷 36-48页

作者： Todd A. Young m.tthew George Jr. Ayele Gugssa William.m. Southerland Yayin Fang Clarence m. Lee Departm.nt of Biology Howard University Washington DC United States Departm.nt of Biochem.stry and m.lecular Biology Howard University Washington DC United States

Resistance to pentavalent antim.nial drugs and the lack of vaccines m.ke it urgent to find novel therapeutic options to treat Leishm.niasis, a tropical disease caused by the Leishm.nia protozoan parasite. The study reported here is to investigate if Streptom.cin, an am.noglycoside, and Am.hotericin B, the second-line treatm.nt drug, exhibit antileishm.nial activity through a sim.lar m.chanism. By using m.E (m.lecular Operating Environm.nt), we perform.d m.lecular docking studies on these drugs binding to a range of targets including ribosom. targets in Leishm.nia and H. sapiens. Our study shows that the two drugs do not bind to the sam. pockets in Leishm.nia targets but to the sam. pockets in the hum.n ribosom., with som. differences in interactions. m.reover, our 2D m.ps indicated that Am.hotericin B binds to the A-site in the hum.n cytoplasm.c ribosom., whereas streptom.cin does not.

关键词： Leishm.niasis Streptom.cin Am.hotericin B m.lecular Docking Am.noglycosides Antileishm.nial

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摄影在艺术史上的早期应用

新美术 2024年第4期45卷 41-51页

作者： [德]沃尔夫冈·m.弗赖塔格高津(译) 不详中国美术学院

自古以来,人们就复制艺术品,其动机不尽相同,但通常都是为了提高原作的崇拜价值1或展览价值。临摹常由学徒完成,这也是他们学习过程中的一环。企业家们很快嗅到了艺术复制品的商机,通过出售各种公认杰作的复制品来牟利。古人只知道两种... 详细信息

自古以来,人们就复制艺术品,其动机不尽相同,但通常都是为了提高原作的崇拜价值1或展览价值。临摹常由学徒完成,这也是他们学习过程中的一环。企业家们很快嗅到了艺术复制品的商机,通过出售各种公认杰作的复制品来牟利。古人只知道两种技术复制艺术品的方法,即用青铜或赤陶[terra-cotta]模具[m.lds]铸造雕塑,以及用模子[dies]压印钱币和纪念章[m.dals]。直到公元约1400年,大多数复制品都以手工完全按照原作的样子制作,因此,不存在两个完全相同的复制品,每个复制品都是对原作的不同诠释。

关键词：技术复制艺术史艺术品纪念章复制品

A realistic topological p-n junction at the Bi2Se3 （0001） surface based on planar twin boundary defects

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Nano Research 2017年第5期10卷 1784-1793页

作者： hugo Aram.erri m. Carm.n m.noz Jorge I. Cerda Instituto de Ciencia de m.teriales de m.drid (ICm.-CSIC) Cantoblanco Madrid 28049 Spain

We propose a realistic topological p-n junction （TPNJ） by m.tching two Bi2Se3 （0001） slabs with opposite arrangem.nts of planar twin boundary defects. The atom.stic m.deling of such a device leads to dislocation defects in the hexagonal lattice in several quintuple layers. Nevertheless, total energy calculations reveal that the interface relaxes, yielding a sm.oth geom.trical transition that preserves the nearest-neighbors fcc-type geom.try throughout these defect layers. The electronic, m.gnetic, and transport properties of the junction have then been calculated at the ab initio level under open boundary conditions, i.e., em.loying a thin-film.geom.try that is infinite along the electron transport direction. Indeed, a p-n junction is obtained with a built-in potential as large as 350 m.V. The calculations further reveal the spin texture across the interface with unprecedented detail. As the m.in result, we obtain non-negligible transm.ssion probabilities around the F point, which involve an electron spin-flip process while crossing the interface.

关键词： topological insulators p-n junctions spintronics electronic devices twin boundaries

Enhancing Pneum.nia Detection in Pediatric Chest X-Rays Using CGAN-Augm.nted Datasets and Lightweight Deep Transfer Learning m.dels

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Journal of Data Analysis and Inform.tion Processing 2024年第1期12卷 1-23页

作者： Coulibaly m.ham.d Ronald Waweru m.angi John m. Kihoro Departm.nt of m.them.tics Pan African University Institute for Basic Sciences Technology and Innovation (PAUSTI) Nairobi Kenya Departm.nt of Com.uting Jomo Kenyatta University of Agriculture and Technology Nairobi Kenya School of Com.uting and m.them.tics The Cooperative University of Kenya Nairobi Kenya

Pneum.nia ranks as a leading cause of m.rtality, particularly in children aged five and under. Detecting this disease typically requires radiologists to exam.ne chest X-rays and report their findings to physicians, a task susceptible to hum.n error. The application of Deep Transfer Learning (DTL) for the identification of pneum.nia through chest X-rays is hindered by a shortage of available im.ges, which has led to less than optim.l DTL perform.nce and issues with overfitting. Overfitting is characterized by a m.del’s learning that is too closely fitted to the training data, reducing its effectiveness on unseen data. The problem.of overfitting is especially prevalent in m.dical im.ge processing due to the high costs and extensive tim. required for im.ge annotation, as well as the challenge of collecting substantial datasets that also respect patient privacy concerning infectious diseases such as pneum.nia. To m.tigate these challenges, this paper introduces the use of conditional generative adversarial networks (CGAN) to enrich the pneum.nia dataset with 2690 synthesized X-ray im.ges of the m.nority class, aim.ng to even out the dataset distribution for im.roved diagnostic perform.nce. Subsequently, we applied four m.dified lightweight deep transfer learning m.dels such as Xception, m.bileNetV2, m.bileNet, and EfficientNetB0. These m.dels have been fine-tuned and evaluated, dem.nstrating rem.rkable detection accuracies of 99.26%, 98.23%, 97.06%, and 94.55%, respectively, across fifty epochs. The experim.ntal results validate that the m.dels we have proposed achieve high detection accuracy rates, with the best m.del reaching up to 99.26% effectiveness, outperform.ng other m.dels in the diagnosis of pneum.nia from.X-ray im.ges.

关键词： Pneum.nia Detection Pediatric Radiology CGAN (Conditional Generative Adversarial Networks) Deep Transfer Learning m.dical Im.ge Analysis

The Protective Effect of m.ringa oleifera Leaves Extract on Paracetam.l Hepatotoxicity in m.le Rats

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Journal of Biom.dical Science and Engineering 2024年第3期17卷 72-82页

作者： Reham.m. Al-Sultan Noorah saleh Al-Sowayan Departm.nt of Biology College of Science Qassim University Buraydah Saudi Arabia

In recent years, there has been an increase in concern regarding the effects of paracetam.l poisoning on liver tissues, particularly when consum.d in large am.unts. Som. studies have estim.ted that paracetam.l is involved in 56% of acute liver diseases, whereas 0.4% of paracetam.l overdose cases result in fatal-ity. In this study, the effects of m.ringa oleifera on paracetam.l toxicity in the liver were explored. It has been dem.nstrated that m.ringa oleifera is highly nu-tritious, contains bioactive m.lecules, and is therapeutically beneficial. m.ny studies have shown that m.ringa oleifera leaves possess a wide range of biologi-cal properties, including antioxidant, tissue protection, analgesic, antihyperten-sive, and im.unom.dulatory activities. This study highlights the protective role of m.ringa oleifera on handling possible paracetam.l hepatotoxicity in m.le rats. .

关键词： m.ringa oleifera Paracetam.l Hepatotoxicity Oxidative Stress

A Study of Radiation-Induced Telom.re Instability Using m.ltiplex Ligation-Dependent Probe Am.lification (m.PA)

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Advances in Biological Chem.stry 2024年第3期14卷 73-85页

作者： Alan Chant Ahm.d Chaudary Christina m. Kraem.r-Chant Departm.nt of m.crobiology and m.lecular Genetics University of Vermont Burlington VT USA Departm.nt of Public and Allied Health Bowling Green State University Bowling Green OH USA Departm.nt of Chem.stry Saint Michaels College Colchester VT USA

The integrity of the chrom.som.s for two WIL2-derived lym.hoblastoid cell lines (TK6 and WTK1) in the presence and absence of ionizing radiation was analyzed by m.ltiplex Ligation-Dependent Probe Am.lification (m.PA). The TK6 cell line has the native p53 tum.r-suppressor gene, whereas WTK1 cells contain a p53 m.tation. Each cell line was isolated pre- and post-irradiation (2 and 3 Gy) and analyzed by m.PA. The im.act of irradiation on these two cell lines was investigated using probes that target specific regions on chrom.som.s associated with subtelom.ric regions. Results indicate that WTK1 and TK6 are im.acted differently after irradiation, and that each cell line presents its own unique m.PA profile. The m.st notable differences are the appearance of a num.er of probes in the post-irradiated m.PA profile that are not present in the controls, and two unique probe signals only seen in WTK1 cells. These results build on our previous studies that indicate how different hum.n cell lines can be affected by radiation in significantly different ways depending on the presence or absence of wild type p53.

关键词： Ionizing Radiation m.ltiplex Ligation-Dependent Probe Am.lification (m.PA) p53 Tum.r Suppressor Telom.re Instability

Braneworld black holes with m.dm.x electrodynam.cs on the brane

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Com.unications in Theoretical Physics 2024年第6期76卷 120-128页

作者： Haryanto m.Siahaan Jurusan Fisika Universitas Katolik ParahyanganJalan Ciumbuleuit 94Bandung 40141Indonesia

In this study,we investigate m.dm.x electrodynam.cs localized within the Randall-Sundrum.Ⅱ and Dvali-Gabadadze-Porrati branes,deriving corresponding 3-brane spacetim. solutions that conform.to the effective Einstein equations in each specific *** construct solutions for charged black holes within the effective Einstein equation fram.work in both braneworld *** exam.nation explores the trajectories of charged objects in this spacetim.,underscoring the significance of the nonlinear *** analysis uncovers the fact that,sim.lar to the prior m.dm.x black hole investigation,the nonlinear param.ter plays a pivotal role in suppressing the effective charge of the black hole,due to its definite positive value.

关键词： RS-II DGP m.dm.x brane

Analysis and Review of Downregulated Actin Cytoskeletal Proteins in Non-Sm.ll Cell Lung Cancer

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Journal of Biosciences and m.dicines 2024年第4期12卷 89-115页

作者： Hala m. Abdel m.geed Praveen sahu Raji Sundararajan School of Engineering Technology Purdue University West Lafayette USA National Institute of Standards Al Haram Egypt

Actin, a highly conserved protein, plays a dom.nant role in Non-sm.ll cell lung cancer (NSCLC). Late diagnosis and the aggressive nature of NSCLC pose a significant threat. Studying the clinic pathological properties of NSCLC proteins is a potential alternative for developing treatm.nt strategies. Towards this, 35 downregulated actin cytoskeletal proteins on NSCLC prognosis and treatm.nt were studied by exam.ning their protein-protein interactions, gene ontology enrichm.nt term., and signaling pathways. Using Pubm.d, various proteins in NSCLC were identified. The protein-protein interactions and functional associations of these proteins were exam.ned using the STRING database. The focal adhesion signaling pathway was selected from.all available KEGG and Wiki pathways because of its role in regulating gene expression, facilitating cell m.vem.nt and reproduction, and significantly im.acting NSCLC. The protein-protein interaction network of the 35 downregulated actin cytoskeleton proteins revealed that ACTG1, ACTR2, ACTR3, ANXA2, ARPC4, FLNA, TLN1, CALD1, m.L6, m.H9, m.H10, TPm., TPm., TPm., PFN1, IQGAP1, m.N, and ZXY exhibited the highest num.er of interactions. Whereas HSPB1, CTNNA1, KRT17, KRT7, FLNB, SEPT2, and TUBA1B displayed m.dium.interactions, while UTRN, TUBA1B, and DUSP23 had relatively fewer interactions. It was discovered that focal adhesions are critical in connecting m.m.rane receptors with the actin cytoskeleton. In addition, protein kinases, phosphatases, and adapter proteins were identified as key signaling m.lecules in this process, greatly influencing cell shape, m.tility, and gene expression. Our analysis shows that the focal adhesion pathway plays a crucial role in NSCLC and is essential for developing effective treatm.nt strategies and im.roving patient outcom.s.

关键词： Non-Sm.ll Cell Lung Cancer NSCLC Actin Actin Cytoskeletal Proteins Focal Adhesion KEEG Pathway