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影视文件快速分割、合并

大众软件 2003年第15期 90-91页

作者： aj

小小的共享软件，真的能解决大问题，在我们的电脑使用过程中，经常会遇到这样一种情况——原本非常复杂的事情被一款不起眼的软件轻松解决。我很感激那些共享软件的开发者，是他们开发的“小”软件给我们日常的电脑使用带来了很大的方... 详细信息

小小的共享软件，真的能解决大问题，在我们的电脑使用过程中，经常会遇到这样一种情况——原本非常复杂的事情被一款不起眼的软件轻松解决。我很感激那些共享软件的开发者，是他们开发的“小”软件给我们日常的电脑使用带来了很大的方便。编写这些软件的作者，基本上不会有什么经济上的收益，也许使用者的感激之情就是他们努力工作的最大回报。支持我们的国产共享软件吧，去使用这些软件、去宣传推广这些软件，为了别人，也为了我们自己……

关键词：共享软件视频分割软件视频合并软件 AVI&MPEG Splitter软件 AVI/MPEG/RM/WMV Joiner软件

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资费便宜网速快移动4G手机推荐

个人电脑 2014年第11期20卷 31-39页

作者： aj王旭

移动4G业务开展已经将近一年的时间,网络覆盖规模已经达到300多个城市,并且移动还将会继续加大投入,优化4G网络调整资费。此外移动作为最早开始商用的4G运营商,支持移动4G网络的终端产品也特别丰富,尤其是在手机方面,众多的厂商都会首... 详细信息

移动4G业务开展已经将近一年的时间,网络覆盖规模已经达到300多个城市,并且移动还将会继续加大投入,优化4G网络调整资费。此外移动作为最早开始商用的4G运营商,支持移动4G网络的终端产品也特别丰富,尤其是在手机方面,众多的厂商都会首先发布支持移动4G网络制式的手机,而在手机的价格方面,4G手机也从数百元至几千元都有选择。下面就为大家介绍几款各价位高性能移动4G手机,对于有购机计划的朋友相信这篇文章会带给大家一些帮助。

关键词：网络制式文章会网络调整网络覆盖酷派四核处理器超窄边框拍照功能感光元件中国移动

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便宜有好货九款百元级游戏鼠标横评

个人电脑 2014年第11期20卷 21-30页

作者： aj王旭

一款游戏鼠标一直都是众多玩家梦寐以求的产品,因为它不仅仅有着炫酷拉风的外观,能够向其他人证明自己是资深游戏玩家的证据,而且在同等水平的较量中,拥有一款好的外设产品,绝对能让你占得先机!笔者认识的玩电竞高手也都表示一款好的游... 详细信息

一款游戏鼠标一直都是众多玩家梦寐以求的产品,因为它不仅仅有着炫酷拉风的外观,能够向其他人证明自己是资深游戏玩家的证据,而且在同等水平的较量中,拥有一款好的外设产品,绝对能让你占得先机!笔者认识的玩电竞高手也都表示一款好的游戏鼠标绝对能给你带来很大的提升。总而言之一款出色的游戏鼠标是你想要玩好游戏的必要条件!那么作为一位游戏玩家一般都会买多少钱的游戏鼠标呢?由于价格因素,百元级的游戏鼠标才是最多用户选择的,本次横评也是看到了这一点,特意选出八个品牌的百元级主力游戏鼠标进行横评对比。

关键词：达尔优狂蛇同等水平给你雷蛇雷柏艾芮幻彩罗技狼蛛

Enantioselective Synthesis of Fluorinated Tetrahedroisoquinoline Derivatives Controlled by Evans' Oxazolidinone

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Enantioselective Synthesis of Fluorinated Tetrahedroisoquino...

中国化学会第十五届全国氟化学会议

作者： Jie Lv aj Deng ZH Li HL Qing Institute of Materia Medica Chinese Academy of Medical Sciences & Peking Union Medical College

A methodology for the enantioselective synthesis of fluorinated tetrahydroisoquinoline derivatives has been developed from Evans’ oxazolidinone analogues, which were produced by Noyori asymmetric reduction of 3,4-dihydroisoquinoline(not shown). Evans’ oxazolidinone has proven effectively achieve the diastereoselective electrophilic fluorination reaction. Davis and Kasu reported that the asymmetric auxiliary controlled addition of an enolate to a fluorine electrophile provides the corresponding α-fluorocarbonyl derivatives in both good yields and high diastereoselectivities. This study details the enantioselectively synthesis of fluorinated tetrahydroisoquinoline derivatives designed to use these stereoelectronic effects to control the bond formation in the further reaction at the α-position of the Evans’ oxazolidinone moiety(not shown).

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羟基氯喹:用法指导

国外医学（皮肤性病学分册） 1993年第3期19卷 158-160页

作者： Carmichael aj 彭学标

羟基氯喹是目前最受欢迎的一种抗疟药,已被用来治疗多种自身免疫性疾病和光线性疾病.本文综述了它的作用机制,副作用以及合理的给药荆量和使用时的注意事项.认为它比氯喹等其它抗疟药更安全和适用.

关键词：羟基氯喹抗疟药

Long-term follow-up of quality of life in high-risk patients undergoing transcatheter aortic valve implantation for symptomatic aortic valve stenosis

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Journal of Geriatric Cardiology 2018年第4期15卷 261-267页

作者： Marjo JAG De Ronde-Tillmans Tom aj de Jager Jeannette A Goudzwaard Nahid El Faquir Nicolas M van Mieghem Felix Zijlstra Elisabeth MWJ. Utens Francesco US Mattace-Raso MaRie J Lenzen Peter PT de Jaegere Erasmus Medical Center Department of Cardiology Thorax Center Rotterdam the Netherlands Erasmus Medical Center Section of Geriatrics Department of Internal Medicine Rotterdam the Netherlands Erasmus Medical Center Department of Child and Adolescent Psychiatry/Psychology Sophia Children 's Hospital Rotterdam the Netherlands The Netherlands Research Institute of Child Development and Education University of Amsterdam the Netherlands

Background Transcatheter aortic valve implantation （TAVI） has become the standard treatment for patients with severe symptomatic aortic stenosis （AS） considered at very high risk for surgical aortic valve replacement. The purpose of this sub-study was to evaluate long-term （〉 4 years） health-related quality of life （QoL） in octogenarians who underwent TAVI. Methods A single center observational registry in twenty patients who underwent frame analysis assessment ≥ 4 years after TAVI. Health-related QoL was evaluated, using the Short Form-36 （SF-36）, the EuroQoL-5D （EQ-5D） and the visual analogue score （EQ-VAS） questionnaires. Results The mean SF-36 subscale scores at follow-up were physical functioning 40.8 ± 26.3, role physical functioning 67.7 ± 34.9, vitality 54.6 ± 21.6, general health 52.1 ± 20.4, social functioning 63.8 ± 37.7, role emotional functioning 70.2 ± 36.0, mental health 73.2 ± 23.3 and bodily pain 80.9 ± 22.9. The mean EQ-VAS score 〉 4 years after TAVI was 64.7 ± 15.1. With respect to functional class, 80% of the patients were in NYHA class I/II at follow-up compared to 15% prior to TAVI. Conclusions This sub-study reports a significant improvement in functional class （NYHA） in a selected group of very elderly patients 〉 4 years after TAVI. Furthermore, all patients showed a satisfactory QoL despite their age and multiple comorbidities. In addition, our study reveals a lower QoL when compared with the general age matched Dutch population.

关键词： Octogenarians Quality of life Transcatheter aortic valve implantation

Biochemical and radiological predictors of malignant biliary strictures

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World Journal of Gastroenterology 2004年第10期10卷 1504-1507页

作者： Ibrahim A.AI-Mofleh Abdulrahman M.Aljebreen Saleh M.AlAmri Rashed S.aj-Rashed Faleh Z.Al-Faleh Hussein M.aj-Freihi Ayman A.Abdo Arthur C.Isnani Gastroenterology Division department of Medicine (38)King Khalid University HospitalRiyadhKingdom of Saudi Arabia King Khalid University Hospital College of Medicine and Research Center (74)PO Box 2925Riyadh 11461Kingdom of Saudi Arabia

AIM: Differentiation of benign biliary strictures (BBS) from malignant biliary strictures (MBS) remains difficult despite improvement in imaging and endoscopic techniques. The aim of this study was to identify the clinical, biochemical and or radiological predictors of malignant biliary ***: We retrospectively reviewed all charts of patients who had biliary strictures (BS) on endoscopic retrograde cholangiopancreatography (ERCP) or percutaneous cholangiography (PTC) in case of unsuccessful ERCP from March 1998 to August 2002. Patient characteristics, clinical features, biochemical, radiological and biopsy results were all recorded. Stricture etiology was determined based on cytology,biopsy or clinical follow-up. A receiver operator characteristic (ROC) curve was constructed to determine the optimal laboratory diagnostic criterion threshold in predicting ***: One hundred twenty six patients with biliary strictures were enrolled, of which 72 were malignant. The mean age for BBS was 53 years compared to 62.4 years for MBS (P=0.0006). Distal bile duct stricture was mainly due to a malignant process 48.6% vs 9% (P=0.001). Alkaline phosphates and AST levels were more significantly elevated in MBS (P=0.0002). ROC curve showed that a bilirubin level of 84 μmol/L or more was the most predictive of MBS with a sensitivity of 98.6%, specificity of 59.3% and a positive likelihood ratio of 2.42 (95% CI=0.649-0.810). Proximal biliary dilatation was more frequently encountered in MBS compared to BBS, 73.8% vs39.5% (P=0.0001). Majority of BBS (87%) and MBS (78%) were managed ***: A serum bilirubin level of 84 μmol/L or greater is the best predictor of MBS. Older age, proximal biliary dilatation, higher levels of bilirubin, alkaline phosphatase, ALT and AST are all associated with MBS. ERCP is necessary to diagnose and treat benign and malignant biliary strictures.

关键词： Biliary Tract Diseases Biliary Tract Neoplasms Constriction, Pathologic Predictive Value of Tests Age Factors Bilirubin Cholangiography Cholangiopancreatography, Endoscopic Retrograde Humans Middle Aged ROC Curve Retrospective Studies Sensitivity and Specificity

Squamous cell carcinoma of the oral cavity in young patients

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中国口腔颌面外科杂志 2008年第B5期6卷 105-106页

作者： Hafeza A Roslan AR Mohd Nazimi aj Primuharsa Putra SHA Ramli R Department of Otorhinolaryngology Head and Neck Surgery Faculty of Medicine Department of Oral & Maxillofacial Surgery Faculty of Dentistry & Hospital UKM Ear Nose & Throat-Head & Neck Consultant Clinic Seremban Specialist Hospital Seremban Negeri Sembilan Malaysia

Purpose: To analyse the pattern of oral cancer in young patients who were seen at the Hospital University Kebangsaan Malaysia (Hospital UKM), Kuala Lumpur, Malaysia。Methods: Patients' records from January 1998 to June 2006 were reviewed。All patients younger than 40 years old were included in the study。Demographic data including gender, age, race, habits and family history were recorded。Tumour and treatment characteristics and current status of the patient were also recorded。Results: 14 cases of squamous cell carcinoma (SCC) in young patients were recorded。Seven males and 7 females were involved with an age range between 19 to 39 years old。Among all the races, Malays showed the highest preponderance (64%), followed by Chinese (29%) and Indians (7%)。The majority of patients (n=11.79%) had no risk factor that could be associated to their tumour。Only 3 patients (21%) had single risk factor, namely smoking behaviour (2 patients) and genetic predisposition (1 patient)。The tongue showed the most occurrence (78%) followed by buccal mucosa (14%) and floor of mouth (8%)。Histologically, most tumours (n=l 1, 78%) were well differentiated SCC and only 3 patient (22%) with moderately differentiated tumour。Surgery in combination with adjuvant radiotherapy were performed in the majority of the patient (76%)。Reconstructive surgery was primarily performed in 4 patients; 2 with platysma flap, 1 pectoralis major and 1 radial forearm flap respectively。Further postoperative follow-up analysis showed that a total of 6 patients had no evidence of recurrent disease, 4 patients (28%) developed recurrence, 2 died of the disease and 2 defaulted follow-up。Conclusion: The pattern and tumour characteristics of oral cancer in young patient did not differ too much from other age groups in our centre。

关键词：口腔鳞状细胞癌诊断方法青少年患者

Cervical cancer in Calabar,Nigeria

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海南医学院学报 2010年第1期16卷 28-32页

作者： Omotoso aj Agan TU Bassey IE Ebughe GA Ekanem IA Ekanem AD Department of Pathology Obstetrics and Gynaecology University of Calabar Teaching Hospital

Objective: To assess the prevalence of cervical cancer and histologic variants as seen in Calabar,Cross River ***: This is a retrospective study involving histologically verified uterine cervix carcinoma between January,1997 and December,***: There were 1,207 malignancies diagnosed during the study period;175(14.5%) were malignancies of the genital tract while 113(9.4.0%) were carcinoma of the cervix constituting 64.6% of female genital *** cancer was commonest between the ages of 40-59 *** was no patient with carcinoma of the cervix below the age of 20 *** cell carcinoma(87.6%) of the uterine cervix was the main histological ***:Cervical cancer is still the most common female genital tract malignancy in Calabar with most of these patients in their middle *** use of PAS/Alcian blue stain as was used in this study eliminates most false-positive squamous cell carcinomas compared with Haematoxylin and Eosin stains used in most reports from most centres in this part of the *** malignancies continue to be the predominant histological variant with squamous cell variety the *** is also an urgent need for introduction of efficient and affordable population based cervical screening programme for early detection,use of vaccines against Human Papilloma Virus(HPV) and treatment of pre-malignant cervical lesions.

关键词：宫颈癌治疗方法临床分析生殖器