检索结果-南通市图书馆

Osthole treatment ameliorates Th2-mediated allergic asthma and exerts immunomodulatory effects on dendritic cell maturation and function

引用

Cellular & Molecular Immunology 2017年第11期14卷 935-947页

作者： Chen-Yuan Chiang Chen-Chen Lee Chia-Kwung Fan huei-mei huang Bor-Luen Chiang Yueh-Lun Lee Division of Pulmonary Medicine Department of Internal MedicineWan Fang HospitalTaipei Medical UniversityTaipei 11031TaiwanChina Department of Internal Medicine School of MedicineCollege of MedicineTaipei Medical UniversityTaipei 11031TaiwanChina Department of Microbiology and Immunology School of MedicineCollege of MedicineChina Medical UniversityTaichung 40402TaiwanChina Department of Parasitology School of MedicineCollege of MedicineTaipei Medical UniversityTaipei 11031TaiwanChina Graduate Institute of Medical Sciences College of MedicineTaipei Medical UniversityTaipei 11031TaiwanChina Graduate Institute of Clinical Medicine College of MedicineNational Taiwan UniversityTaipei 10048TaiwanChina Department of Microbiology and Immunology School of MedicineCollege of MedicineTaipei Medical UniversityTaipei 11031TaiwanChina

Osthole,an active component of Chinese herbal medicines,reportedly possesses various pharmacological properties and has potential therapeutic *** study explored the anti-allergic effects of osthole in asthmatic mice and investigated the immunomodulatory actions of osthole on dendritic cells(DCs)and T ***,we show that oral administration of osthole to BALB/c mice after ovalbumin(OVA)sensitization ameliorated all of the cardinal features of T helper 2(Th2)-mediated allergic asthma;namely,the production of OVA-specific immunoglobulin E,airway hyperresponsiveness,airway inflammation and the production of Th2-type cytokines including interleukin(IL)-4,IL-5 and ***,IL-10 production was not inhibited and was even enhanced by osthole *** observed a significant increase in the percentages of IL-10-producing DCs and forkhead box P3-positive regulatory T(Treg)cells in osthole-treated asthmatic ***,in vitro analyses revealed that osthole-treated bone-marrow-derived DCs had a partial maturation phenotype,secreting large amounts of IL-10 and low levels of proinflammatory cytokines,such as IL-12,IL-6 and tumor necrosis factor-α,and displaying reduced levels of MHC class II surface *** DCs displayed immunosuppressive capacity by directly inhibiting effector T-cell responses or inducing Treg *** addition,osthole directly inhibited the activated CD4+T-cell proliferation and Th1/Th2-type cytokine production in this ***,these results suggest that DCs and T cells are potential target cells responsible for the action of osthole against allergic asthma.

关键词： asthma dendritic cell osthole T cell

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Analysis of the anti-T2DM components in dichloromethane fraction of Schisandra sphenanthera and its mechanism

引用

Traditional Medicine Research 2025年第1期10卷 27-43页

作者： Shi-Bo Feng Hai-Hui Jiang Hui-Li Kang Yi Jiang Hua-Wei Zhang Xiao-mei Song Yu-Ze Li Wen-Li huang Dong-Dong Zhang Chong Deng School of Pharmacy Shaanxi University of Chinese MedicineXianyang 712046China School of Pharmacy and Shaanxi Qinling Application Development and Engineering Center of Chinese Herbal Medicine Shaanxi University of Chinese MedicineXianyang 712046China Key Laboratory for Research and Development of“Qin Medicine”of Shaanxi Administration of Traditional Chinese Medicine Xianyang 712046China Shaanxi Key Laboratory of Research and Application of“Taibai Qi Yao” Xianyang 712046China

Background:The type 2 diabetes mellitus(T2DM)pharmacodynamic study of various parts of Schisandra sphenanthera was conducted in the previous stage,and it was found that dichloromethane extracted part(SDP)had a significant hypoglycemic ***,the components of SDP were analyzed,and the specific mechanism of its anti-T2DM was ***:We used a high-fat,high-sugar diet in combination with streptozotocin to induce a T2DM rat model,and the model rats were divided into two groups according to body weight and blood ***,oral glucose tolerance test,fasting blood glucose,low density lipoprotein cholesterol,superoxide dismutase,insulin,glycated hemoglobin,total cholesterol,nonesterified free fatty acids,alanine aminotransferase,high-density lipoprotein cholesterol,aspartate aminotransferase,malondialdehyde,and glutathione peroxidase were measured,organ indices were calculated,and pathological sections of pancreas and liver were *** 16S rRNA V3–V4 region of intestinal flora was sequenced to explore the effect of SDP on biochemical indicators and intestinal *** on the above indicators,the anti-T2DM mechanism of SDP in Schisandra sphenanthera was ***:After six weeks of administration,the biochemical indices of diabetic rats were diminished compared to the control *** SDP could significantly increase the gut microbialα-diversity index,resulting in significant changes in the flora of T2DM rats,with increased richness and diversity,reduced harmful flora,and significantly back-regulated the levels of acetic acid,propionic acid,and butyric ***:SDP can improve the symptoms associated with elevated blood glucose,dyslipidemia,elevated fasting insulin levels,and damaged glucose tolerance in *** against T2DM may be through the control of intestinal flora to normalize and exert anti-diabetic effect;its main active components may be lignans and terpenoids.

关键词： Schisandra sphenanthera T2DM intestinal flora HPLC

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Photon polarization tensor in a magnetized plasma system

引用

Communications in Theoretical Physics 2020年第11期72卷 57-64页

作者： Jingyi Chao mei huang Institute of Modern Physics Chinese Academy of SciencesLanzhou730000China School of Physics Sciences University of Chinese Academy of SciencesBeijing 100039China

We investigate the photon polarization tensor at finite temperatures in the presence of a static and homogeneous external magnetic *** our scheme,the summing of the Matsubara frequency is performed after Poisson resummation,which is easily completed and converges ***,the behaviors of finite Landau levels are presented *** shows a convergence while summing infinite Landau ***,there is no necessity to truncate the Landau level in a numerical *** zero temperature,the lowest Landau level(LLL)approximation is analytically satisfied for the vacuum photon polarization ***,we examine that the LLL approximation is not enough for the thermal polarization *** thermal tensor obtains non-trivial contributions from the finite-n Landau ***,photon spectra gains a large imaginary contribution in thermal medium,which is the so-called Landau ***,it is argued that the summation of Matsubara frequency is not commuted with Landau level ones,such conjecture is excluded in our calculations.

关键词： magnetic field thermal field theory photon polarization Landau damping

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Assessing spatio-temporal variations of precipitation-use efficiency over Tibetan grasslands using MODIS and in-situ observations

引用

Frontiers of Earth Science 2016年第4期10卷 784-793页

作者： Zhengjia LIU mei huang Key Laboratory of Ecosystem Network Observation and Modeling Institute of Geographic Sciences and Natural Resources Research Chinese Academy of Sciences Beijing 100101 China State Key Laboratory of Remote Sensing Science Institute of Remote Sensing and Digital Earth Chinese Academy of Sciences Beijing 100101 China

Clarifying the spatial and temporal variations in precipitation-use efficiency （PUE） is helpful for advancing our knowledge of carbon and water cycles in Tibetan grassland ecosystems. Here we use an integrated remote sensing normalized difference vegetation index （NDVI） and in-situ above-ground net primary production （ANPP） measurements to establish an empirical exponen- tial model to estimate spatial ANPP across the entire Tibetan Plateau. The spatial and temporal variations in PUE （the ratio of ANPP to mean annual precipitation （MAP））, as well as the relationships between PUE and other controls, were then investigated during the 2001- 2012 study period. At a regional scale, PUE increased from west to east. PUE anomalies increased significantly （〉 0.1 g.m^-***^-1/10 yr） in the southern areas of the Tibetan Plateau yet decreased （〉 0.02 g. m^-2. mm 1/10 yr） in the northeastern areas. For alpine meadow, we obtained an obvious breaking point in trend of PUE against elevation gradients at 3600 m above the sea level, which showed a contrasting relationship. At the inter-annual scale, PUE anomalies were smaller in alpine steppe than in alpine meadow. The results show that PUE of Tibetan grasslands is generally high in dry years and low in wet years.

关键词： normalized difference vegetation index(NDVI) Tibetan Plateau inter-annual variations alpinegrasslands exponential model

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Magnetic correction to the anomalous magnetic moment of electrons

引用

Communications in Theoretical Physics 2022年第5期74卷 75-85页

作者： Fan Lin mei huang School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China

We investigate the leading order correction of anomalous magnetic moment(AMM) to electrons in a weak magnetic field and find that the magnetic correction is negative and magnetic field dependent, indicating a magnetic catalysis effect for the electron gas. In the laboratory, to measure the g-2, the magnitude of the magnetic field B is several T, and correspondingly the magnetic correction to the AMM of electron/muon is around 10^(-34)/10^(-42), therefore the magnetic correction can be safely neglected in the current measurement. However, when the magnitude of the magnetic field strength is comparable with the electron mass, the magnetic correction of the electron’s AMM will become considerable. This general magnetic correction to the charged fermion’s AMM can be extended to study quantum chromodynamic matter under a strong magnetic field.

关键词： anomalous magnetic moment magnetic correction magnetic field

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Laser light scattering technique for non-invasive in situ simultaneous measurements on elastic constants and viscosity coefficients of nematic liquid crystals

引用

Science China(Physics,Mechanics & Astronomy) 2004年第1期47卷 79-85页

作者： TU mei huang Yaoxiong Institute of Biomedical Engineering Jinan University Guangzhou 510632 China Institute of Biomedical Engineering Jinan University Guangzhou 510632 China

The laser light scattering technique for non-invasivein situ simultaneous measurements on elastic constants and viscosity coefficients of nematic liquid crystals is introduced. By measuring the autocorrelation function of the scattered light from nematic liquid crystals at different scattering angles, the splay and twist elastic constantsK 11 andK 22 are obtained from the amplitudes of the autocorrelation function, and the viscosity coefficients ofη Splay andη Twist are determined using the viscoelastic ratiosK 11/η Splay andK 22 η Twist from the telaxation parameters of the two modes.

关键词： dynamic light scattering, nematic liquid crystal, elastic constants, viscosity coefficients.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A Numerical-analytic Method for Quickly Predicting Springback of Numerical Control Bending of Thin-walled Tube

引用

Journal of Materials Science & Technology 2006年第5期22卷 713-720页

作者： mei ZHAN He YANG Liang huang College of Materials Science and Engineering Northwestern Polytechnical University Xi＇an 710072 China

Springback is one of important factors influencing the forming quality of numerical control （NC） bending of thin-walled tube. In this paper, a numerical-analytic method for springback angle prediction of the process was put forward. The method is based on springback angle model derived using analytic method and simulation results from three-dimensional （3D） rigid-plastic finite element method （FEM）. The method is validated through comparison with experimental results. The features of the method are as follows：（1） The method is high in efficiency because it combines advantages of rigid-plastic FEM and analytic method. （2） The method is satisfactory in accuracy, since the field variables used in the model is resulting from 3D rigid-plastic FEM solution, and the effects both of axial force and strain neutral axis shift have been included. （3） Research on multi-factor effects can be carried out using the method due to its advantage inheriting from rigid-plastic FEM. The method described here is also of general significance to other bending processes.

关键词： Thin-walled tube Numerical control bending Springback Numerical-analytic method 3D rigid-plastic FEM

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Theoretical Studies on the Fe-M Interactions and 31p NMR in Fe（CO）3（EtPhPpy）2MX2 （X=NCS, SCN, CI; M=Zn, Cd, Hg）

引用

Chinese Journal of Chemical Physics 2008年第5期21卷 438-444页

作者： Xiao-xuan huang Xuan Xu mei-xiang Xie School of Chemistry and Environment Key Lab of Technology on Electrochemical Energy Storage and Power Generation in Guangdong Universities South China Normal University Guangzhou 510006 China

To study the Fe-M interactions and their effects on 31p NMR, the structures of Fe（CO）3（EtPhPpy）2 1, Fe（CO）3（EtPhPpy）2M（NCS）2 （2： M=Zn, 3： M=Cd, 4： M=Hg） and Fe（CO）3（EtPhPpy）2CdX2 （5： X=C1, 6： X=SCN） were investigated by density functional theory （DFT） PBE0 method. The stabilities S of complexes follow S（2）〉S（3）〉S（4） and S（3）,.~S（6）〉S（5）, indicating that 6 is stable and may be synthesized. The complexes with thiocyanate are more stable than that with chloride in Fe（CO）3（EtPhPpy）2CdX2. The strength I of Fe-M interactions follows I（2）≈I（3）〈I（4）. The Fe-Cd interactions of 3 and 6, which contain thiocyanate, are stronger than that of 5 with chloride. The charge-transfer, which enhances with the increasing of Fe-M interaction strength, comes from Et, Ph, py, CO groups towards P, Fe, and M atoms. Because the delocalization of thiocyanate disperses the charge of M2＋, the charge-transfer of the complexes with thiocyanate is stronger than that with chloride. There is a a-bond between Fe and Hg atoms in 4. However, in binuclear complexes except 4, the Fe-M interactions act as nFe→nM, σP-Fe→nM and σC-Fe→nM delocalization, and the N-M interactions mainly act as nN→nM delocalization. In binuclear complexes, due to the Fe→M interactions, the strong σFe--C→σ＊Fe--p or σFe-Hg→σ＊Fe--I2 delocalization and the charge-transfer, the electron density on P nucleus is increased, and thus upfield 31p chemical shifts are caused （compared with mononuclear complex 1）.

关键词： DFT 31p NMR Metal-metal interaction Nature bond orbital

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Fishery Web Service Composition Method Based on Ontology

引用

Journal of Integrative Agriculture 2012年第5期11卷 792-799页

作者： YU Qing-mei WANG Lan huang Dong-mei School of Information Technology Shanghai Ocean UniversityShanghai 201306P.R.China

Various fishery information systems have been developed in different times and on different platforms. Wet） service application composition is crucial in the sharing and integration of fishery data and information. In the present paper, a heuristic web service composition method based on fishery ontology is presented, and the proposed web services are described. Ontology reasoning capability was applied to generate a service composition graph. The heuristic function was introduced to reduce the searching space. The experimental results show that the algorithm used considers the services semantic similarity and adiusts web service composition plan by dynamically relying on the empirical data.

关键词： web services composition semantic similarity fishery ontology heuristic function

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Location Service Information Supporting System Based on Ontology

引用

Journal of Integrative Agriculture 2012年第5期11卷 858-864页

作者： huang Dong-mei FANG Qian YU Qing-mei College of Information Shanghai Ocean UniversityShanghai 201306P.R.China

In order to solve the problem of how to collect and manage large amount of location information and improve the accuracy of location service, interactive information supporting system based on ontology and location service is presented in this paper. It can transmit special information about users＇ location to front-end instantaneously, so it is very convenient for their daily life. It makes full use of the available wireless communication, which is easy to arrange and convenient for users.

关键词： ontology location service location information supporting system

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：