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Epidural chloroma and spinal cord compression

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Chinese Medical Journal 2019年第7期132卷 853-855页

作者： Hyun jung Koh jungwon Baek Min Soo Lee hue jung park Department of Anesthesiology and Pain Medicine Seoul St.Mary's HospitalCollege of MedicineThe Catholic University of KoreaSeoul 06591Korea

To the Editor:Chloroma is a rare solid tumor that was formed sometimes from malignant myeloid blast cells outside the hematopoietic system;these are known as chloroma or granulocytic sarcoma[1]Chloroma can be diagnosed anywhere outside of the hematopoietic system,such as the head and neck,skeletal system,breast,uterus,and central nervous system.[2]This tumor is common in leukemic patients.[3]Chloroma presents as an epidural mass resulting in spinal cord compression with neurologic symptoms.[4]Spinal lesions occur most frequently at the thoracic level;however,the most common primary symptoms are low back pain and radiating pain in the legs[5].

关键词： Epidural chloroma spinal cord compression hematopoietic system

Unexpected Pulmonary Events during Endotracheal Intubation in a Pediatric Patient

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Chinese Medical Journal 2017年第18期130卷 2263-2264页

作者： hue jung park Haewon Chung Min Soo Lee Hyun jung Koh Department of Anesthesiology and Pain Medicine Seoul St. Mary's Hospital College of Medicine The Catholic University of Korea Seoul 06591Republic of Korea

Nearly 21% of pediatric surgical operations are accompanied by adverse events,12.8% of which are respiratory complications including bronchospasm （1.2%） and pulmonary edema （11%）. Among them,aspiration pneumonia and negative-pressure pulmonary edema are rare pulmonary complications in pediatrics.However,they are difficult to predict and can be fatal if not appropriately treated;careful monitoring is required.We present a case of pulmonary complication secondary to aggravation of bronchial spasm during intubation of a pediatric patient.

关键词： Aspiration Bronchial Spasm Intubation Pneumonia

A new technique of ganglion impar pulsed radiofrequency ablation

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Chinese Medical Journal 2021年第10期134卷 1221-1223页

作者： Ji Yeong Kim Sung Eun Sim Subin Yoo Mina Joo hue jung park Department of Anesthesiology and Pain Medicine Seoul St.Mary’s HospitalCollege of MedicineThe Catholic University of KoreaSeoul 06591Republic of Korea

The ganglion impar block was first introduced in 1990 by Plancarte et al.[1]Since then,several modified versions have been reported by Wemm and Saberski,[2]Nebab and Florence,[3]and Foye.[4]They tried to reduce pain effectively by considering the anatomy of the ganglion impar and coccyx.There were differences in the strengths of each individual’s technique.However,owing to the anatomical diversity of the structure itself,[5]it was difficult to determine which technique would be more effective.Radiofrequency ablation(RFA)developed in the ganglion impar block also faced this controversy.In this clinical background,we present a new technique to implement ganglion impar RFA.Written informed consent was obtained from the patient before the initiation of the study.

关键词： anatomy technique. al.

Safe drug treatment and procedure for herpes zoster in pregnancy:a case report

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Chinese Medical Journal 2020年第16期133卷 1999-2000页

作者： Ji Yeong Kim You Ri Ko Sung Eun Sim Sua Oh Mi Hyeon Lee hue jung park Department of Anesthesiology and Pain Medicine Seoul St.Mary’s HospitalCollege of MedicineThe Catholic University of KoreaSeoulRepublic of Korea

To the Editor:A first infection of varicella-zoster virus(VZV)during pregnancy can cause serious systemic disease to both mother and the fetus.Despite this maternal herpes zoster(HZ)does not increase fetal mortality,and the transmission of varicella-zoster virus to the fetus rarely occurs.Although HZ infection has a minimal effect on the fetus,maternal HZ can cause significant complications for the mother.

关键词： zoster mother pregnancy fetal

Spontaneous Absorption of a Lumbar Epidural Hematoma after Interlaminar Epidural Steroid Injection in a Patient with Spinal Stenosis： Close Observation as a Treatment Strategy

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Chinese Medical Journal 2018年第1期131卷 117-118页

作者： Soo Hyang Kim Yun Joung Han Young Hoon Kim Jae Min Lee Yoo Mi Kim hue jung park Department of Anesthesiology and Pain Medicine College of Medicine Seoul St. Mary's Hospital The Catholic University of Korea Seoul 06591 Korea

To the Editor： A lumbar epidural block is used to treat patients with a herniated intervertebral disc, spinal stenosis, or lumbosacral radiculopathy. This approach reduces radicular pain by decreasing inflammation of nerve roots through epidural corticosteroid injection. Patients with moderate-to-severe spinal stenosis who taking various anticoagulant agents have more risk for epidural hematoma.

关键词： Spontaneous Absorption a Lumbar Epidural Hematoma after Interlaminar

Utilization of biomarkers for the prognostic prediction of cardiac arrest survivors using a multi-modal approach

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World Journal of Emergency Medicine 2024年第2期15卷 131-134页

作者： Changshin Kang Yeonho You jung Soo park Byeong Kwon park Jae Kwang Lee Byung Kook Lee Department of Emergency Medicine College of MedicineChungnam National UniversityDaejeon 35015Republic of Korea Department of Emergency Medicine Chungnam National University HospitalDaejoen 35015Republic of Korea Department of Emergency Medicine Konyang University HospitalCollege of MedicineDaejeon 35015Republic of Korea Department of Emergency Medicine Chonnam National University Medical SchoolChonnam National University HospitalGwangju 61469Republic of Korea

International guidelines for post-cardiac arrest care recommend using multi-modal strategies to avoid the withdrawal of life-sustaining therapy(WLST)in patients with the potential for neurological recovery.[1]However,a clear methodology for multi-modal approaches has yet to be developed.Neuron-specific enolase(NSE)is currently the only recommended biomarker,and the European Resuscitation Council(ERC)and the European SocietyofIntensiveCareMedicine(ESICM)have proposed a cutoff value of 60μg/L at 48 and/or 72 h after the return of spontaneous circulation(ROSC)as a multimodal prognostic tool for predicting poor neurological outcomes.

关键词： cardiac modal return

Primary Ewing sarcoma of the kidney mimicking cystic papillary renal cell carcinoma in an older patient:A case repor

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World Journal of Clinical Cases 2024年第15期12卷 2606-2613页

作者： Suhong Kim Jongsoo park Young Hwii Ko Hee jung Kwon Department of Radiology Yeungnam UniversityDaegu 42415South Korea Department of Urology Yeungnam UniversityDaegu 42415South Korea Department of Pathology Yeungnam UniversityDaegu 42415South Korea

BACKGROUND Ewing’s sarcoma(ES)is a neuroectodermal tumor that typically occurs in the bones and soft tissues of children and young adults.Primary renal ES is rare;only a few cases and a small case series have been documented,and only four cases involved primary renal ES in older people(>65 years old).CASE SUMMARY Herein,we describe the radiological and pathological features of primary renal ES in an older person.A 76-year-old man complained of poor oral intake and was found to have a large cystic renal mass with indistinct margins on computed tomography.Ultrasound-guided biopsy revealed that the tumor contained small round blue cells.The patient underwent a right radical nephrectomy.The tumor cells showed diffuse membranous CD99,and nuclear friend leukemia integration 1 transcription factor and NK2 Homeobox 2.Fluorescence in situ hybridization revealed EWSR1 translocation.Postoperatively,18F-fluorodeoxyglucose positron emission tomography revealed no evidence of metastasis.The patient was diagnosed with primary renal ES.Six months following the surgery,local recurrence and distant metastasis were observed.Primary renal ES is rare and often lethal in older individuals.The specific imaging findings are unknown,and treatment protocols have not been standardized.CONCLUSION This case report describes the radiological and pathological features of primary renal ES in an older person.

关键词： Ewing sarcoma Elder Renal Kidney Neuroectodermal Case report

Oxygen vacancy engineering for tuning the catalytic activity of LaCoO_(3) perovskite

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Journal of Rare Earths 2024年第3期42卷 506-514,I0003页

作者： Jeong Hyun Cho Minjae Kim Inchan Yang Kyung Tae park Chang Houn Rhee Hai Woong park Ji Chul jung Department of Chemical Engineering Myongji UniversityYongin 17058Republic of Korea Institute of Advanced Composite Materials Korea Institute of Science and TechnologyWanju-gunJeollabuk-do 55324Republic of Korea Iron&Steel Process Engineering Research Group POSCOPohang 37859Republic of Korea Hydrogen Research Center Research Institute of Industrial Science&Technology(RIST)Pohang 37673Republic of Korea

Herein, we attempted to engineer oxygen vacancies on the surface of LaCoO_(3) perovskite through simple post-treatments(acid or reductive thermal treatments). Acid treatment induces oxygen vacancies through the selective etching of the La cations, whereas thermal treatment in a reducing atmosphere generates oxygen vacancies by directly removing lattice oxygen. The characterization results confirm that the number of surface oxygen vacancies, which are crucial in various catalytic oxidation reactions,considerably increases in the LaCoO_(3) catalysts treated with acid or reducing gas. Acid treatment enriches the oxygen vacancies while maintaining the structure of the LaCoO_(3) catalysts, which can not be achieved through reductive thermal treatment. Therefore, the acid treatment is considered a promising technique for oxygen vacancy engineering of perovskite catalysts for tuning their catalytic activities. Furthermore,the catalytic activities of the posttreated LaCoO_(3) catalysts for CO oxidation were evaluated and are noted to be considerably better than those of the pristine LaCoO_(3) catalyst due to their abundant oxygen vacancies. Consequently, we conclude that the oxygen vacancies of perovskite catalysts can be effectively engineered via two simple methods and play a significant role in CO oxidation.

关键词： LaCoO_(3)perovskite Acid treatment Reductive thermal treatment Oxygen vacancy CO oxidation Rare earths

ELK3-ID4 axis governs the metastatic features of triple negative breast cancer

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Oncology Research 2024年第1期32卷 127-138页

作者： JIN-HO CHOI JOO DONG park SEUNG HEE CHOI EUN-SU KO HYE jung JANG KYUNG-SOON park Department of Biomedical Science CHA UniversitySeongnamKorea

Purpose:Cancer cell metastasis is a multistep process,and the mechanism underlying extravasation remains unclear.ELK3 is a transcription factor that plays a crucial role in regulating various cellular processes,including cancer metastasis.Based on the finding that ELK3 promotes the metastasis of triple-negative breast cancer(TNBC),we investigated whether ELK3 regulates the extravasation of TNBC by forming the ELK3-ID4 axis.ID4 functions as a transcriptional regulator that interacts with other transcription factors,inhibiting their activity and subsequently influencing various biological processes associated with cell differentiation,survival,growth,and metastasis.Methods:We assessed the correlation between the expression of ELK3 and that of ID4 in TNBCs using bioinformatics analyses,QRT-PCR,western blot analysis,luciferase reporter assays,and chromatin immunoprecipitation.Migration,adhesion,invasion,and lung metastasis assays were employed to determine whether the ELK3-ID4 axis regulates the metastatic features of TNBC.Results:We found that ELK3 binds directly to a binding motif close to the ID4 promoter to repress promoter activity.The expression of E-cadherin in TNBC was regulated by the ELK3-ID4 axis.In vitro and in vivo analyses showed that inhibiting ID4 expression in ELK3-knockdown MDA-MB-231(ELK3KD)cells restored the ability to extravasate and metastasize.Conclusion:The results indicate that the ELK3 regulates ID4 promoter activity,and that the ELK3-ID4 axis regulates the metastatic characteristics of TNBC cells.Additionally,the data suggest that the ELK3-ID4 axis regulates metastasis of TNBCs by modulating expression of E-cadherin.

关键词： E-cadherin Extravasation Colonization