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Inhibitive effects of chlortetracycline on performance of the nitritation-anaerobic ammonium oxidation(anammox)process and strategies for recovery

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Journal of Environmental Sciences 2018年第8期30卷 29-36页

作者： Hong Yao huayu li Jing Xu Lushen Zuo Beijing Key Laboratory of Aqueous Typical Pollutants Control and Water Quality Safeguard Department of Municipal and Environmental Engineering Beijing Jiaotong University

The short-and long-term effects of chlortetracycline（CTC） on the nitritation-anaerobic ammonium oxidation（anammox） process were evaluated. The half maximal inhibitory concentration of CTC in the batch tests of the nitritation-anammox process was 278.91 mg/L at an exposure time of 12 hr. The long-term effects of CTC on the process were examined in a continuous-flow nitritation-anammox reactor. Within 14 days, the nitrogen removal rate significantly decreased from 0.61 to 0.25 kg N/m^3/day with 60 mg/L CTC in the *** performance suppressed by CTC barely recovered, even after CTC was removed from the influent. Furthermore, the inhibition of CTC also reduced the relative abundance of ammonium oxidizing bacteria（AOB） and anaerobic ammonium oxidizing bacteria（An AOB）in the reactor, resulting in both a decreased amount of and an imbalance between AOB and An AOB. When fresh anammox sludge was reseeded into the nitritation-anammox reactor,the nitrogen removal rate recovered to 0.09 ± 0.03 kg N/m3/day.

关键词： Nitritation-anammox process Anaerobic ammonium oxidizing bacteria (AnAOB) Ammonium oxidizing bacteria (AOB) Chlortetracycline

Deep-learning-based extraction of the animal migration patterns from weather radar images

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Science China(Information Sciences) 2020年第4期63卷 59-68页

作者： Kai CUI Cheng HU Rui WANG Yi SUI Huafeng MAO huayu li Radar Research Laboratory School of Information and Electronics Beijing Institute of Technology Key Laboratory of Electronic and Information Technology in Satellite Navigation (Beijing Institute of Technology) Ministry of Education

Continental coverage and year-round operation of the weather radar networks provide an unprecedented opportunity for studying large-scale airborne migration. The broad and local-scale airborne information collected by these infrastructures can answer many ecological questions. However, extracting and interpreting the biological information from such massive weather radar data remains an intractable problem. Recently, many big-data problems have been solved using the deep learning technology. In this study, the biological information in the weather radar data is identified using the advanced deep learning method. The proposed method consists of two main parts, i.e., a rendering and casting procedure and an image segmentation procedure based on a convolutional neural network. The biological data are automatically extracted by rendering and mapping, image segmentation, and result masking. By analyzing the typical radar data from single and multiple stations, we partly reveal the intensity and speed of the migration pattern. We present the first feasibility study of the extraction of local and large-scale biological phenomena from the Chinese weather radar network data.

关键词： weather radar deep learning aerial animal migration pattern Chinese weather radar network

Inhibition of growth and metastasis of human gastric cancer implanted in nude mice by d-limonene

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World Journal of Gastroenterology 2004年第14期10卷 2140-2144页

作者： Xiao-GuangLu li-BinZhan Bing-AnFeng Ming-YangQu li-huayu Ji-HongXie DalianMedicalUniversityMolecularBiologicalLaboratoryforChineseTraditionalMedicine Dalian116027LiaoningProvinceChina DalianMedicalScienceInstituteg Dalian116001LiaoningProvinceChina DepartmentofGeneralSurgery TheFourthAffiliatedHospitalofDalianMedicalUniversityDalian116001LiaoningProvinceChina

AIM:To investigate the effects and mechanism of d-limonene on the growth and metastasis of gastric cancer in ***: Metastatic model simulating human gastric cancer was established by orthotopic implantation of histologically intact human tumor tissue into gastric wall of nude mice. One percent d-limonene was orally administered at dose of 15 ml/kg every other day for seven weeks. Eight weeks after implantation, tumor weight,inhibition rate, apoptotic index (AI), microvessel density (MVD), vascular endothelial growth factor (VEGF), variation of ultrastructure, and the presence of metastasis were evaluated, respectively, after the mice were ***: The tumor weight was significantly reduced in 5-FU group (2.55±0.28 g), d-limonene group (1.49±0.09 g)and combined treatment group (1.48±0.21 g) compared with the control group(2.73±0.23 g, P＜0.05). In 5-FU group, d-limonene group, combined treatment group, the inhibition rates were 2.60%,47.58% and 46.84% and 0,respectively;AI was (3.31±0.33)%,(8.26±1.21)%,(20.99±1.84)% and (19.34±2.19)%, respectively; MVD was (8.64±2.81), (16.77±1.39), (5.32±4.26) and (5.86±2.27), respectively; VEGF expression was (45.77±4.79), (41.34±5.41),(29.71±8.92) and (28.24±8.55), respectively. The incidences of peritoneal metastasis also decreased significantly in 5-FU group(77.8%), d-limonene group(20.0%) and combined group (22.2%) compared with control group (100%) versus 62.5%,30% and 22.2%)(P＜0.05). liver metastasis was also inhibited and the incidences decreased significantly in 5-FU group, d-limonene group and combined group than that in control group (87.5% vs 55.5%, 20.0% and 22.2% respectively)(P＜0.05). The incidence of ascites in control group, 5-FU group, d-limonene group and combined group was 25.0%,22.2%, 0, 0, respectively and 12.5%, 11.1% 0, 0, with respect to the metastasis rate to other ***: d-limonene has antiangiogenic and proapoptotic effects on gastric cancer, thereby inhibits tumor growth and

关键词：抑制作用生长作用细胞转移胃癌灌注治疗裸鼠 d-柠檬油精肿瘤

Mg/Fe site-specific dual-doping to boost the performance of cobalt-free nickle-rich layered oxide cathode for high-energy lithium-ion batteries

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Journal of Energy Chemistry 2024年第4期91卷 670-679页

作者： Yunting Wang Gaohui Du Di Han Wenhao Shi Jiahao Deng huayu li Wenqi Zhao Shukai Ding Qingmei Su Bingshe Xu Materials Institute of Atomic and Molecular Science Shaanxi University of Science and TechnologyXi'an 710021ShanxiChina Shanxi-Zheda Institute of Advanced Materials and Chemical Engineering Taiyuan 030024ShanxiChina Key Laboratory of Interface Science and Engineering in Advanced Materials Taiyuan University of TechnologyTaiyuan 030024ShanxiChina

Layer-type liNi0.9Mn0.1O2is promising to be the primary cathode material for lithium-ion batteries(liBs)due to its excellent electrochemical ***,the cathode with high nickel content suffers from severely detrimental structural transformation that causes rapid capacity ***,site-specific dual-doping with Fe and Mg ions is proposed to enhance the structural stability of *** Fe3+dopants are inserted into transition metal sites(3b)and can favorably provide additional redox potential to compensate for charge and enhance the reversibility of anionic *** Mg ions are doped into the li sites(3a)and serve as O_(2)^(-)-Mg^(2+)-O_(2)^(-)pillar to reinforce the electrostatic cohesion between the two adjacent transition-metal layers,which further suppress the cracking and the generation of harmful phase transitions,ultimately improving the *** theoretical calculations,including Bader charge and crystal orbital Hamilton populations(COHP)analyses,confirm that the doped Fe and Mg can form stable bonds with oxygen and the electrostatic repulsion of O_(2)^(-)-O_(2)^(-)can be effectively suppressed,which effectively mitigates oxygen anion loss at the high delithiation *** dual-site doping strategy offers new avenues for understanding and regulating the crystalline oxygen redox and demonstrates significant potential for designing high-performance cobalt-free nickel-rich cathodes.

关键词： Cobalt-free Layered oxide Cathode Dual dopants Density functional theory calculation

Correlation of ATP7B genotype with phenotype in Chinese patients with Wilson disease

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World Journal of Gastroenterology 2004年第4期10卷 590-593页

作者： xiao-Qingliu Ya-FenZhang Tze-Tzeliu Kwang-JenHsiao Jian-MingZhang Xue-FanGu Ke-RongBao li-huayu Mei-XianWang DepartmentofNeurology XinhuaHospitalShanghaiSecondMedicalUniversityShanghai200092China ShanghaiInstituteforPediatricResearch Shanghai200092China GenomeResearchCenterandInstituteofGenetics NationalYangMingUniversityandDepartmentofMedicalResearchandEducationTaipeiVeteransGeneralHospitalTaipei11216TaiwanChina

AIM:To determine the mutational characterization of Ptype ATP7B gene and to explore the correlation of ATP7B genotype to phenotype in Chinese patients with Wilson disease (WD).METHODS: Seventy-five patients with WD from 72 no-kinship families,44 males and 31 females, were enrolled in this *** age of onset ranged from 4 to 39 years,≤18 years in 72 patients. Some exons of ATP7B gene mutations were analyzed in patients with WD by using biochemical methods,polymerase chain reaction-single strand configuration polymorphism (PCR-SSCP) and DNA sequence analysis. A total of 778 coding regions were identified with restriction enzyme Msp I. The activity of Cu-ATPase was assessed by measuring inorganic ***: Sixty-six of 75 patients (88%) had with hepatic manifestations, 39 of them had only hepatic manifestations,27 patients had hepatic and neurological manifestations or other symptoms at the same time (16 patients had associated neurological manifestation, 3 patients had osteopathy, 8 patients had other symptoms). Eight of the 75 patients (10.7%) had only neurological symptoms, one patient (5 years old) had no symptom. Twelve changing patterns were detected in ATP7B gene by DNA sequencing, induding seven mutations (R778L, C656X, G943D, V1140A, Vl106I V1216M and 1384de117), six polymorphisms (IVS4-5t/c, A2495G, C2310G,IVS18+6c/t and IVS20+5a/g). R778L occurred in 49/66 patients (74%) with hepatic manifestations, homozygosis of R778L in 16 patients, heterozygosity of R778L in 33 patients. V1106I mutation of ATP7B gene occurred in 2 patients with delaying onset of clinical symptoms. Cu-ATPase activity of three patients with known mutations (R778L/V1106I/A2495G, R778L/V1216M and R778L/R778L) were determined; and the activity of Cu-ATPase was decreased by 44.55%, 88.23% and 69.49% ***:1384del17bp is a novel mutation found in WD patients.R778L is the most common mutation of ATP7B gene. There is a correlation between R778L and hepatic manifest

关键词：肝豆状核变性 ATP7B基因 PCR-SSCP 基因多态性 DNA序列分析

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供水管网计算分区方法的比较分析

哈尔滨工业大学学报 2021年第5期53卷 48-58页

作者：李化雨吴珊侯本伟程玉林北京工业大学建筑工程学院北京100124

针对现有的供水管网计算分区方法研究多基于单个管网案例进行验证,缺乏不同案例、不同需求下的比较和适用性分析的问题,基于深度优先搜索-部分接近度算法(DFS-PCC)、快速迭代模块度的贪心算法(CNM)和遗传优化的谱聚类算法(GA-SC)3种方法... 详细信息

针对现有的供水管网计算分区方法研究多基于单个管网案例进行验证,缺乏不同案例、不同需求下的比较和适用性分析的问题,基于深度优先搜索-部分接近度算法(DFS-PCC)、快速迭代模块度的贪心算法(CNM)和遗传优化的谱聚类算法(GA-SC)3种方法,采用标准化互信息(NMI)、模块度、节点数均衡性、联络管数量等分区结果评价指标,在5个标准管网案例上比较其分区效果.比较分析时考虑了不同管网案例的拓扑结构、水源数量和类型、控制元件等固有属性差异,并讨论方法的赋权和分区数的确定问题.结果表明:DFS-PCC对区域供水特征明显、树状特性较高的案例分区,所得结果模块度较高,但联络管数量较多;CNM对区域供水特征明显、树状特性较高的案例分区,所得结果NMI较高,联络管数量较少;GA-SC在5个不同案例中,模块度较高、区域间节点数较均衡、联络管数量较少,总体适用性良好;使用该方法1/q的赋权形式,可有效选择流量和流量波动性大的管道作为联络管.

关键词：供水管网计算分区复杂网络模块度谱聚类

Virtual Data Center for Material Science Based on MATML

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Virtual Data Center for Material Science Based on MATML

第二届亚洲材料数据库会议

作者： Changjun Hu~* huayu li Chunping Ouyang Information Engineering School University of Science and Technology Beijing Beijing 100083 China

＜正＞With the rapid development of material informatics,large number of material science data is generated and then used as valuable information resource for material scientific computing and analysis. However,the fact that these data sets are usually distributed,heterogeneous and lack of uniform data format specification leads to difficulty in data retrieval and sharing;traditional data integration framework cannot solve semantic heterogeneity and unable to meet the needs of data acquisition and exchange in Web *** this case,we propose a virtual data center（VDC） for material science using semantic data integration and Web services *** VDC utilize global ontology extracted from MatML as data access views with which users submit semantic-query statements to underlying data sources,and after processed according to MatML format the data results will return to users in the form of Web service;because of not storing underlying raw data,VDC avoids such problems as data update and inconsistencies. In practical,VDC provides a powerful platform for material data sharing and can promote the development of material informatics.

关键词： MatML Ontology Virtual Views Web Services

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高速铁路信道小尺度衰落与非平稳特性研究

铁道学报 2019年第4期41卷 88-95页

作者：周涛李华玉秦鑫彤文辉陶成北京交通大学电子信息工程学院北京100044 东南大学移动通信国家重点实验室江苏南京211189

高速铁路的快速发展使得高速铁路无线信道特性的研究成为热点,但高速铁路信道测量的不易性也使目前的研究工作仍存在不足之处。以北京—天津(京津)城际高速铁路无线信道的具体环境为基础,在平原、车站、城郊3个典型的高速铁路环境中,从... 详细信息

高速铁路的快速发展使得高速铁路无线信道特性的研究成为热点,但高速铁路信道测量的不易性也使目前的研究工作仍存在不足之处。以北京—天津(京津)城际高速铁路无线信道的具体环境为基础,在平原、车站、城郊3个典型的高速铁路环境中,从两方面深入剖析高速铁路信道的传播特性。一方面,通过莱斯K因子、时延扩展、到达角以及功率角度谱等信道参数,研究高速铁路信道的小尺度衰落特性;另一方面,把以功率相关性为基础的稳态间隔作为特征参数来刻画高速铁路信道的非平稳特性,并基于有限状态的马尔科夫链模型,分析高铁信道多径传播的时变特性。

关键词：高速铁路信道小尺度衰落角度特性非平稳性马尔科夫链

SYNTHESIS AND APPliCATION OF THE NOVEL PAM EMULSION AS PAPER DRY-STRENGTHING AGENT

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天津科技大学学报 2004年第A1期19卷 215-219页

作者： Jianwenli huayuQiu ShandongInstituteoflight-Industry Jinan250100Chma

The synthesis of a novel type of polyacrylamide emulsion as dry-strengthing agent was studied in this paper. Several strength agents were obtained by changing reaction conditions such as reaction time, species and doses of initiator, reaction concentration and so on. Meanwhile, the application of these strength agents in papermaking of wheat straw slurry was also discussed. In addition, the obvious increases in dry strength of paper comparable to using currently available cationic dry strength agents at the same dose were given by using these strength agents.

关键词：乳胶聚丙烯酰胺小麦秸杆泥浆干燥强度去末剂造纸工业