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Nano Research 2017年第3期10卷 785-793页

作者： huayang li li Su Shuangyang Kuang Youjun Fan Ying Wu Zhong lin Wang Guang Zhu Beijing Institute of Nanoenergy and Nanosystems Chinese Academy of Sciences National Center for Nanoscience and Technology (NCNST) Beijing 100083 China Chongqing University of Science and Technology Chongqing 401331 China School of Materials Science and Engineering Georgia Institute of Technology A tlanta GA 30332 USA

We fabricate a flexible hybrid nanogenerator （HNG）, based on multilayered nanocomposite materials, which integrates a piezoelectric nanogenerator （PENG） and a triboelectric nanogenerator （TENG） into a single structure with only two electrodes. The HNG enables enhancement of the electrical output of the nano- generators. An open-circuit voltage of 280 V and a short-circuit current of 25 μA are achieved by a HNG of 2.5 cm × 2.5 cm in size, superior to the performance of previously reported HNGs. In addition, the energy-conversion process of the HNG relies on the working mechanism of both the PENG and TENG. The polarization direction and doping content of BTO are the two major factors that affect the electrical output. Biomechanical energy harvesting from walking motion or the bending of an arm is also demonstrated.

关键词： energy harvesting nanocomposite hybrid nanogenerator piezoelectricity triboelectricity

Efficient genome editing in grapevine using CRISPR/LbCas12a system

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Molecular Horticulture 2023年第1期3卷 111-123页

作者： Chong Ren Elias Kirabi Gathunga Xue li huayang li Junhua Kong Zhanwu Dai Zhenchang liang Beijing Key Laboratory of Grape Sciences and Enology Beijing 100093PR China State Key Laboratory of Plant Diversity and Specialty Crops Beijing 100093PR China China National Botanical Garden Beijing 100093PR China University of Chinese Academy of Sciences Beijing 100049PR China Institute of Botany the Chinese Academy of SciencesHaidian DistrictNanxin Village 20XiangshanBeijing 100093China

Clustered regularly interspaced short palindromic repeats(CRISPR)/Cas12a system,also known as CRISPR/Cpf1,has been successfully harnessed for genome engineering in many plants,but not in grapevine *** we developed and demonstrated the efficacy of CRISPR/Cas12a from Lachnospiraceae bacterium ND2006(LbCas12a)in inducing targeted mutagenesis by targeting the tonoplastic monosaccharide transporter1(TMT1)and dihydroflavonol-4-reductase 1(DFR1)genes in 41B *** of DFR1 gene altered flavonoid accumulation in dfr1 mutant *** treatment(34℃)improved the editing efficiencies of CRISPR/LbCas12a system,and the editing efficiencies of TMT1-crRNA1 and TMT1-crRNA2 increased from 35.3%to 44.6%and 29.9%to 37.3%after heat treatment,***,the sequences of crRNAs were found to be predominant factor affecting editing efficiencies irrespective of the positions within the crRNA array designed for multiplex genome *** addition,genome editing with truncated crRNAs(trucrRNAs)showed that trucrRNAs with 20 nt guide sequences were as effective as original crRNAs with 24 nt guides in generating targeted mutagenesis,whereas trucrRNAs with shorter regions of target complementarity≤18 nt in length may not induce detectable mutations in 41B *** these results provide evidence for further applications of CRISPR/LbCas12a system in grapevine as a powerful tool for genome engineering.

关键词： Vitis vinifera CRISPR LbCas12a Multiplex editing crRNA length Flavonoid

High sensitivity and broad linearity range pressure sensor based on hierarchical in-situ filling porous structure

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npj Flexible Electronics 2022年第1期6卷 581-592页

作者： Jin Xu huayang li Yiming Yin Xin li Jinwei Cao Hanfang Feng Wandi Bao Hao Tan Fanyuan Xiao Guang Zhu New Materials Institute Department of MechanicalMaterials and Manufacturing EngineeringUniversity of Nottingham Ningbo China315100 NingboChina CAS Key Laboratory of Magnetic Materials and Devices Ningbo Institute of Materials Technology and EngineeringChinese Academy of Sciences315201 NingboChina School of Nanoscience and Technology University of Chinese Academy of Sciences100049 BeijingChina Ningbo Sezen Technology Co. Ltd315042 NingboChina College of Mechanical and Electrical Engineering Beijing University of Chemical Technology100029 BeijingChina

Flexible piezoresistive pressure sensor with high sensitivity over a broad linearity range have been attracting tremendous attention for its applications in health monitoring,artificial intelligence,and human-machine ***,we report a hierarchical insitu filling porous piezoresistive sensor(HPPS)by direct ink writing(DIW)printing and curing of carbon nanofibers(CNFs)/polydimethylsiloxane(PDMS)*** geometry significantly increases the contact area,distributes stress to multilayered lattice and internal porous structure,resulting in a broad sensing ***,unlike conventional hollow porous structure,the CNFs networks in-situ filling porous structure generates more contact sites and conductive pathways during compression,thereby achieving high sensitivity and linearity over entire sensing ***,the optimized HPPS achieves high sensitivity(4.7 kPa^(−1))and linearity(coefficient of determination,R^(2)=0.998)over a broad range(0.03-1000 kPa),together with remarkable response time and ***,the applications in diverse pressure scenarios and healthcare monitoring are demonstrated.

关键词： porous structure attracting

The Clausena lansium genome provides new insights into alkaloid diversity and the evolution of the methyltransferase family

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Journal of Integrative Agriculture 2024年第10期23卷 3537-3553页

作者： Yongzan Wei Yi Wang Fuchu Hu Wei Wang Changbin Wei Bingqiang Xu liqin liu huayang li Can Wang Hongna Zhang Zhenchang liang Jianghui Xie State Key Laboratory of Biological Breeding of Tropical Crops Institute of Tropical Bioscience and BiotechnologyChineseAcademy of Tropical Agricultural SciencesHaikou 571101China Key Laboratory of Genetic Resources Evaluation and Utilization of Tropical Fruits and Vegetables(Co-construction by Ministryand Province) Ministry of Agriculture and Rural Affairs/Institute of Tropical Fruit TreesHainan Academy of Agricultural SciencesHaikou 571100China Beijing Key Laboratory of Grape Sciences and Enology CAS Key Laboratory of Plant ResourcesInstitute of BotanyChineseAcademy of SciencesBeijing 100093China Key Laboratory of Tropical Fruit Biology(Ministry of Agriculture and Rural Affairs) South Subtropical Crops Research InstituteChinese Academy of Tropical Agricultural SciencesZhanjiang 524091China Haikou Experimental Station Chinese Academy of Tropical Agricultural SciencesHaikou 571101China Sanya Institute of Breeding and Multiplication/School of Tropical Agriculture and Forestry Hainan UniversityHaikou 570228China Sanya Research Academy Chinese Academy of Tropical Agricultural SciencesSanya 572019China

Wampee(Clausena lansium)is an important evergreen fruit tree native to southern China that has a long history of use for medicinal ***,a chromosome-level genome of *** was constructed with a genome size of 282.9 Mb and scaffold N50 of 30.75 *** assembled genome contains 48.70%repetitive elements and 24,381 protein-coding *** genomic analysis showed that *** diverged from Aurantioideae 15.91-24.95 million years ***,some expansive and specific gene families related to methyltransferase activity and S-adenosylmethionine-dependent methyltransferase activity were also *** analysis indicated that N-methyltransferase(NMT)is mainly involved in alkaloid biosynthesis and O-methyltransferase(OMT)participates in the regulation of coumarin accumulation in *** suggested that wampee's richness in alkaloids and coumarins might be due to the gene expansions of NMT and *** tandem repeat event was one of the major reasons for the NMT ***,the reference genome of *** will facilitate the identification of some useful medicinal compounds from wampee resources and reveal their biosynthetic pathways.

关键词： Clausena lansium genome evolution methyltransferase activity alkaloid biosynthesis coumarin accumulation

Ultra-robust stretchable electrode for e-skin:In situ assembly using a nanofiber scaffold and liquid metal to mimic water-to-net interaction

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InfoMat 2022年第4期4卷 124-137页

作者： Jinwei Cao Fei liang huayang li Xin li Youjun Fan Chao Hu Jing Yu Jin Xu Yiming Yin Fali li Dan Xu Hanfang Feng Huali Yang Yiwei liu Xiaodong Chen Guang Zhu Run-Wei li New Materials Institute Department of MechanicalMaterials and Manufacturing EngineeringUniversity of Nottingham Ningbo ChinaNingboChina CAS Key Laboratory of Magnetic Materials and Devices Ningbo Institute of Materials Technology and EngineeringChinese Academy of SciencesNingboChina Zhejiang Province Key Laboratory of Magnetic Materials and Application Technology Ningbo Institute of Materials Technology and EngineeringChinese Academy of SciencesNingboChina Innovative Center for Flexible Devices(iFLEX) Max Planck-NTU Joint Lab for Artificial SensesSchool of Materials Science and EngineeringNanyang Technological UniversitySingaporeSingapore CAS Center for Excellence in Nanoscience Beijing Key Laboratory of Micro-Nano Energy and SensorBeijing Institute of Nanoenergy and NanosystemsChinese Academy of SciencesBeijingChina Institute of Textiles&Clothing The Hong Kong Polytechnic UniversityHong KongChina State Key Lab of New Ceramics and Fine Processing School of Materials Science and EngineeringTsinghua UniversityBeijingChina

The development of stretchable electronics could enhance novel interface structures to solve the stretchability-conductivity dilemma,which remains a major ***,we report a nano-liquid metal(LM)-based highly robust stretchable electrode(NHSE)with a self-adaptable interface that mimics water-tonet *** on the in situ assembly of electrospun elastic nanofiber scaffolds and electrosprayed LM nanoparticles,the NHSE exhibits an extremely low sheet resistance of 52 mΩsq^(-1).It is not only insensitive to a large degree of mechanical stretching(i.e.,350%electrical resistance change upon 570%elongation)but also immune to cyclic deformation(i.e.,5%electrical resistance increases after 330000 stretching cycles with 100%elongation).These key properties are far superior to those of the state-of-the-art *** robustness and stability are verified under diverse circumstances,including long-term exposure to air(420 days),cyclic submersion(30000 times),and resilience against mechanical *** combination of conductivity,stretchability,and durability makes the NHSE a promising conductor/electrode solution for flexible/stretchable electronics for applications such as wearable on-body physiological signal detection,human-machine interaction,and heating e-skin.

关键词： crack confinement functional e-skin in situ assembly self-adaptable interface ultra-robust stretchable electrode

Fine-control-valve of halide perovskite single crystal quality for high performance X-ray detection

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Science Bulletin 2021年第21期66卷 2199-2206,M0004页

作者： Weijun li huayang li Jinmei Song Chunjie Guo Huimao Zhang Haotong Wei Bai Yang State Key Laboratory of Supramolecular Structure and Materials College of ChemistryJilin UniversityChangchun 130012China Joint Laboratory of Opto-Functional Theranostics in Medicine and Chemistry The First Hospital of Jilin UniversityChangchun 130061China Department of Radiology The First Hospital of Jilin UniversityChangchun 130012China

Halide perovskite single crystals(HPSCs)provide a unique platform to study the optoelectronic properties of such emerging semiconductor materials,while the temperature induced crystal growth method often has an increased solute integration speed and/or unavoidable solute consumption,resulting in a soaring or slumping crystal growth rate of ***,we developed a universal and facile solvent-vola tilization-limited-growth(SVG)strategy to finely control the crystal growth rate by the fine-control-valve for high quality crystal grown through solution *** grown HPSCs by SVG method exhibited a record low trap density of 2.8×10^(8)cm^(-3)and a high charge carrier mobility-lifetime product(μτproduct)of 0.021 cm2/V,indicating the excellent crystal *** crystal surface defects were further passivated by oxygen suppliers as Lewis base,which led to a reduction of surface leakage current by two times when using for low dose rate X-ray *** HPSC X-ray detector displayed a high sensitivity of 1274μC/(Gyair cm^(2))with a lowest detectable dose rate of 0.56μGyair/s under 120 keV hard *** applications including alloy composition analysis and metal flaw detection by HPSC detectors were also demonstrated,which not only shows the bright future for product quality inspection and non-destructive materials analysis,but also paves the way for growing high quality single crystals and fabricating polycrystalline films.

关键词： Perovskite single crystal Solution-processed Crystal growth strategy Sensitive X-ray detectors

不同结构轴向磁通永磁电机的有限元设计与对比研究（英文）

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电工技术学报 2015年第14期30卷 32-40页

作者：李华阳沈建新浙江大学电气工程学院杭州310027

针对特定用途的轴向磁通永磁电机,开展相关分析与设计。考虑到特殊的外形尺寸,对永磁体径向宽度、轴向厚度,定子齿尖厚度等关键尺寸进行了参数化设计。优化了三种不同结构的轴向磁通电机,同时针对电磁性能以及定子振动模态进行了对比研... 详细信息

针对特定用途的轴向磁通永磁电机,开展相关分析与设计。考虑到特殊的外形尺寸,对永磁体径向宽度、轴向厚度,定子齿尖厚度等关键尺寸进行了参数化设计。优化了三种不同结构的轴向磁通电机,同时针对电磁性能以及定子振动模态进行了对比研究,分别是双定子中间转子结构的AFIR电机,双转子中间定子结构的TORUS-NN和TORUS-NS电机。三维有限元计算以及理论分析方法验证了整个优化过程。

关键词：轴向磁通电机优化设计定子振动模态有限元分析

晶体硅太阳电池背面套印图形设计对电池性能和组件性能的影响

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太阳能学报 2020年第9期41卷 155-160页

作者：张良李化阳李良姚玉王霞王俊镇江大全太阳能有限公司扬中212211

以晶体硅太阳电池背面套印图形为研究对象,通过设计背电场和背电极套印方式以及背电极图形,对背面不同套印图形的接触电阻、电池的电性能和组件性能进行研究。研究结果表明:背面铝背场和银电极在重叠面积为4.35%,且背电极蜈蚣脚间距为1... 详细信息

以晶体硅太阳电池背面套印图形为研究对象,通过设计背电场和背电极套印方式以及背电极图形,对背面不同套印图形的接触电阻、电池的电性能和组件性能进行研究。研究结果表明:背面铝背场和银电极在重叠面积为4.35%,且背电极蜈蚣脚间距为1 mm时的接触电阻最小,电池效率提升最大,同时组件输出功率增益最多。该研究为晶体硅太阳电池背面套印图形设计和背电极图形的优化提供指导。

关键词：太阳电池丝网印刷转换效率背电极背电场

卵巢交界性黏液性肿瘤合并CA724特异性升高1例报道并文献复习

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中国医科大学学报 2024年第9期53卷 858-861页

作者：李华洋张颐中国医科大学附属第一医院妇科沈阳110001

回顾性分析1例卵巢交界性黏液性肿瘤合并糖类抗原724(CA724)特异性升高患者的临床资料并复习相关文献,探讨肿瘤标志物CA724升高在卵巢交界性黏液性肿瘤的早期诊断、鉴别诊断、复发监测中的临床价值。

关键词：糖类抗原724 卵巢交界性黏液性肿瘤诊断鉴别诊断

Programmable robotized‘transfer-and-jet’printing for large,3D curved electronics on complex surfaces

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International Journal of Extreme Manufacturing 2021年第4期3卷 74-87页

作者： YongAn Huang Hao Wu Chen Zhu Wennan Xiong Furong Chen lin Xiao Jianpeng liu Kaixin Wang huayang li Dong Ye Yongqing Duan Jiankui Chen Hua Yang Wenlong li Kun Bai Zhouping Yin Han Ding State Key Laboratory of Digital Manufacturing Equipment and Technology Huazhong University of Science and TechnologyWuhanPeople’s Republic of China Flexible Electronics Research Center Huazhong University of Science and TechnologyWuhanPeople’s Republic of China

Large,3D curved electronics are a trend of the microelectronic industry due to their unique ability to conformally coexist with complex surfaces while retaining the electronic functions of 2D planar integrated circuit ***,these curved electronics present great challenges to the fabrication ***,we propose a reconfigurable,mask-free,conformal fabrication strategy with a robot-like system,called robotized‘transfer-and-jet’printing,to assemble diverse electronic devices on complex *** novel method is a ground-breaking advance with the unique capability to integrate rigid chips,flexible electronics,and conformal circuits on complex ***,each process,including transfer printing,inkjet printing,and plasma treating,are mask-free,digitalized,and *** robotization techniques,including measurement,surface reconstruction and localization,and path programming,break through the fundamental constraints of 2D planar microfabrication in the context of geometric shape and *** transfer printing begins with the laser lift-off of rigid chips or flexible electronics from donor substrates,which are then transferred onto a curved surface via a dexterous robotic *** the robotic electrohydrodynamic printing directly writes submicrometer structures on the curved *** permutation and combination allow versatile conformal ***,robotized hybrid printing is utilized to successfully fabricate a conformal heater and antenna on a spherical surface and a flexible smart sensing skin on a winged model,where the curved circuit,flexible capacitive and piezoelectric sensor arrays,and rigid digital–analog conversion chips are *** hybrid printing is an innovative printing technology,enabling additive,noncontact and digital microfabrication for 3D curved electronics.

关键词： conformal printing curved electronics complex surfaces inkjet printing robotic fabrication