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Building Simulation 2021年第4期14卷 1311-1323页

作者： Longxing Yu huaxian wan.jie ji State Key Laboratory of Fire Science University of Science and Technology of ChinaJinZhai Road 96HefeiAnhui230026China College of Environment and Resources Fuzhou UniversityXueyuan Road 2FuzhouFujian350116China

This paper has analyzed the asymmetric flow effect of fire-induced thermal flow in a horizontal tunnel under the natural ventilation condition by conducting large eddy simulations (LES). The key objective is to reveal and to have a better understanding of the asymmetric flow effect caused by the upstream and downstream tunnel length difference. The mechanism behind it can be explained based on the conservation of mass and dynamic force analysis on the smoke and fresh air. The strength of the asymmetric flow effect is characterized by the mass flow rate of the induced longitudinal flow (net mass flow rate of a cross-section). An empirical correlation to predict the induced longitudinal mass flow rate is proposed. Furthermore, the law of smoke and air flow distribution within a horizontal tunnel is established. The proportion of smoke (or air) flowing out (or coming in) through the opening increase (or decrease) linearly with the increasing distance between that opening to the fire location. The variation of the air flow with the longitudinal fire location in a tunnel is more sensitive than the smoke flow. Results have shown that as the fire approaches the tunnel exit from the middle of the tunnel, the smoke spilling out through this opening is reduced from 50% to 40%, while the fresh air incoming from this opening is increased from 50% to 100% and vice versa.

关键词： asymmetric flow effect fire location thermal flow smoke tunnel fire CFD

A method of determining flame radiation fraction induced by interaction burning of tri-symmetric propane fires in open space based on weighted multi-point source model

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Frontiers in Energy 2022年第6期16卷 1017-1026页

作者： jie ji Junrui DUAN huaxian wan State Key Laboratory of Fire Science University of Science and Technology of ChinaHefei 230026China Institute of Advanced Technology University of Science and Technology of ChinaHefei 230088China

The interaction of multiple fires may lead to a higher flame height and more intense radiation flux than a single fire,which increases the possibility of flame spread and risks to the *** were conducted using three burners with identical heat release rates(HRRs)and propane as the fuel at various *** results show that flames change from non-merging to merging as the spacing decreases,which result in a complex evolution of flame height and merging point *** facilitate the analysis,a novel merging criterion based on the dimensionless spacing S/z_(c) was *** non-merging flames(S/z_(c)>0.368),the flame height is almost identical to a single fire;for merging flames(S/z_(c)≤0.368),based on the relationship between thermal buoyancy B and thrust P(the pressure difference between the inside and outside of the flame),a quantitative analysis of the flame height,merging point height,and air entrainment was formed,and the calculated merging flame heights show a good agreement with the measured experimental ***,the multi-point source model was further improved,and radiation fraction of propane was *** data obtained in this study would play an important role in calculating the external radiation of propane fire.

关键词： flame interaction air entrainment flame height multi-point source model thermal radiation

High‑Entropy Electrode Materials:Synthesis,Properties and Outlook

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Nano-Micro Letters 2025年第1期17卷 472-506页

作者： Dongxiao Li Chang Liu Shusheng Tao jieming Cai Biao Zhong jie Li Wentao Deng Hongshuai Hou Guoqiang Zou Xiaobo ji College of Chemistry and Chemical Engineering Central South UniversityChangsha 410083People’s Republic of China School of Chemistry and Chemical Engineering Hunan Institute of EngineeringXiangtan 411104People’s Republic of China

High-entropy materials represent a new category of high-performance materials,first proposed in 2004 and extensively investigated by researchers over the past two *** definition of high-entropy materials has continuously *** the last ten years,the discovery of an increasing number of high-entropy materials has led to significant advancements in their utilization in energy storage,electrocatalysis,and related domains,accompanied by a rise in techniques for fabricating high-entropy electrode ***,the research emphasis has shifted from solely improving the performance of high-entropy materials toward exploring their reaction mechanisms and adopting cleaner preparation ***,the current definition of high-entropy materials remains relatively vague,and the preparation method of high-entropy materials is based on the preparation method of single metal/low-or medium-entropy *** should be noted that not all methods applicable to single metal/low-or medium-entropy materials can be directly applied to high-entropy *** this review,the definition and development of high-entropy materials are briefly ***,the classification of high-entropy electrode materials is presented,followed by a discussion of their applications in energy storage and catalysis from the perspective of synthesis ***,an evaluation of the advantages and disadvantages of various synthesis methods in the production process of different high-entropy materials is provided,along with a proposal for potential future development directions for high-entropy materials.

关键词： High-entropy Energy storage Electrode materials

Nanomaterials-mediated lysosomal regulation:a robust protein-clearance approach for the treatment of Alzheimer’s disease

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Neural Regeneration Research 2025年第2期20卷 424-439页

作者： Mengqi Hao jianjian Chu Tinglin Zhang Tong Yin Yuankai Gu Wendanqi Liang Wenbo ji jianhua Zhuang Yan Liu jie Gao You Yin Department of Neurology Second Affiliated Hospital of Naval Medical University(Shanghai Changzheng Hospital)ShanghaiChina School of Health Science and Engineering University of Shanghai for Science and TechnologyShanghaiChina Changhai Clinical Research Unit Shanghai Changhai HospitalNaval Medical UniversityShanghaiChina Department of Clinical Pharmacy Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Department of Neurology Shanghai East HospitalSchool of MedicineTongji UniversityShanghaiChina

Alzheimer’s disease is a debilitating,progressive neurodegenerative disorder characterized by the progressive accumulation of abnormal proteins,including amyloid plaques and intracellular tau tangles,primarily within the ***,crucial intracellular organelles responsible for protein degradation,play a key role in maintaining cellular *** studies have suggested a link between the dysregulation of the lysosomal system and pathogenesis of neurodegenerative diseases,including Alzheimer’s *** the normal physiological function of lysosomes hold the potential to reduce the pathological burden and improve the symptoms of Alzheimer’s ***,the efficacy of drugs in treating Alzheimer’s disease is limited,with major challenges in drug delivery efficiency and ***,nanomaterials have gained widespread use in Alzheimer’s disease drug research owing to their favorable physical and chemical *** review aims to provide a comprehensive overview of recent advances in using nanomaterials(polymeric nanomaterials,nanoemulsions,and carbon-based nanomaterials)to enhance lysosomal function in treating Alzheimer’s *** review also explores new concepts and potential therapeutic strategies for Alzheimer’s disease through the integration of nanomaterials and modulation of lysosomal *** conclusion,this review emphasizes the potential of nanomaterials in modulating lysosomal function to improve the pathological features of Alzheimer’s *** application of nanotechnology to the development of Alzheimer’s disease drugs brings new ideas and approaches for future treatment of this disease.

关键词： Alzheimer’s disease autophagy dysfunction lysosomal acidification lysosomal system nanomaterials neurodegenerative diseases

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认知空间映射及其神经机制

心理科学进展 2025年第1期33卷 62-76页

作者：吴际李会杰南宁师范大学教育科学学院南宁530001 中国科学院行为科学重点实验室(中国科学院心理研究所) 北京100101 中国科学院大学心理学系北京100049

认知地图不仅可以映射物理空间,还可以支持认知空间映射,形成包括感知空间、情景记忆空间、概念空间和社会空间等在内的跨不同信息领域的地图式表征。认知空间映射的神经机制包括海马体对潜在结构的抽象和概括、支持分布式位置地图的生... 详细信息

认知地图不仅可以映射物理空间,还可以支持认知空间映射,形成包括感知空间、情景记忆空间、概念空间和社会空间等在内的跨不同信息领域的地图式表征。认知空间映射的神经机制包括海马体对潜在结构的抽象和概括、支持分布式位置地图的生成、将信息与背景结构捆绑,以及海马体与其它脑区的协同。未来研究应关注预测性的认知空间地图、海马体对不同精度和层级信息的表征、认知空间映射微观和介观层面的研究空缺以及物理空间和认知空间映射的共同机制和特异性机制等问题。

关键词：认知地图网格细胞位置细胞海马体

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Unraveling the mechanism of action of Shangxia Liangji formula for treating insomnia:a metabolomics and network pharmacology approach

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Traditional Medicine Research 2025年第2期10卷 16-29页

作者： Xia-jie Quan Hao Liang Yong-Hong Tang Li jiang Xiong-Ying ji Feng-Ying Zhang Ping Zhang Bo Ouyang Department of Information The Affiliated Nanhua HospitalHengyang Medical SchoolUniversity of South ChinaHengyang 421002China Department of Neurology The Affiliated Nanhua HospitalHengyang Medical SchoolUniversity of South ChinaHengyang 421002China Department of Gastroscopy The Affiliated Nanhua HospitalHengyang Medical SchoolUniversity of South ChinaHengyang 421002China Department of Traditional Chinese Medicine The Affiliated Nanhua HospitalHengyang Medical SchoolUniversity of South ChinaHengyang 421002China

Background:Insomnia is a prevalent clinical condition and Shangxia Liangji formula(SXLJF)is a well-established method of ***,the specific mechanism of action of SXLJF remains ***:The mouse model of insomnia was established by intraperitoneal injection of ***-two mice were randomly divided into a negative control group,model group,SXLJF group(18.72 g/kg/day),and positive control group(diazepam,2 mg/kg)and treated with the corresponding drugs for 7 consecutive *** open field test and pentobarbital-induced sleeping test were ***-MS-based untargeted metabolomics and network pharmacology were applied to explore the potential targets of SXLJF for treating ***,key targets were validated using ***:Behavioral tests demonstrated that SXLJF reduced the total distance,average velocity,central distance,and sleep latency,and prolonged sleep *** and network pharmacology revealed potential targets,signaling pathways,metabolic pathways,and metabolites associated with the anti-insomnia effects of ***,tyrosine hydroxylase(TH)and tyrosine metabolism emerged as crucial metabolic pathways and targets,***-qPCR results supported the role of TH in the mechanism of SXLJF in treating ***:In conclusion,TH and tyrosine metabolism may represent significant targets and pathways for SXLJF in treating insomnia.

关键词： Shangxia Liangji formula insomnia metabolomics network pharmacology tyrosine hydroxylase tyrosine metabolism

Glacier Variation in Response to Climate Change in Chinese Tianshan Mountains from 1989 to 2012

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Journal of Mountain Science 2015年第5期12卷 1189-1202页

作者： HE Yi YANG Tai-bao ji Qin CHEN jie ZHAO Gang SHAO wan-wan College of Earth and Environmental Sciences Lanzhou University

Based on the 1990, 2000 and 2011 Landsat TM/ETM+ remote sensing data, glacier information of three periods in the Chinese Tianshan Mountains were extracted by using ratio threshold method(TM3/TM5) and visual interpretation, combined with digital processing of satellite images and analysis in GIS. The climate data in the surrounding area were analyzed by using linear regression, Mann-Kendall abrupt test, and Morlet wavelet analysis. Study results showed that: over the 23 years investigation, the glacier areas have markedly decreased. In the last 12 years(2000 to 2011), the rate of retreat has begun to accelerate. The most dramatic glacier shrinkage occurred in the central region, the lowest in the eastern region. The mean summer temperature and warm precipitation in Chinese Tianshan Mountains had an increasing trend, with rates of 0.22°C /10 a and 5.1mm/10 a from 1960 to 2011, respectively. Mean summer temperature have experienced a strong increase in 1998. The analysis of the results showed that the rise of mean summer temperature was the main factor that contributed to glacier shrinkage. Regional differences of glacier area changes were investigated by analyzing glacier behavior in five study sub-regions; regional differences are related to local climate, to the relative proportion of glaciers in different size classes, altitudinal and aspect distribution of glaciated areas. In addition, the lag theory indicated that glaciers may accelerate the retreat in the next decade, considering climate trends recognized for the period 2000-2011.

关键词： Climate variation Glacier Remotesensing Tianshan

Performance Analysis of NOMA-Based Cooperative Networks with Relay Selection

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China Communications 2020年第11期17卷 111-119页

作者： Ronglan Huang Dehuan wan Fei ji Hua Qing jie Li Hua Yu Fangjiong Chen Guangxi Colleges and Universities Key Laboratory of Image Processing and Intelligent Information System Wuzhou UniversityWuzhou 543002China Guangdong University of Finance Guangzhou 510521China School of Electronic and Information Engineering South China University of TechnologyGuangzhou 510641China Key Laboratory of Marine Environmental Survey Technology and Application Ministry of Natural ResourcesGuangzhou510300China

Non-orthogonal multiple access(NOMA)technique is an expert on channel differences *** this paper,a dual-hop NOMA-based cooperative relaying network where a best relay is selected as an active node to accomplish the communication between a source and a destination is *** assume that both decode-and-forward(DF)and amplify-and-forward(AF)protocols are applied to the selected *** metrics that ergodic sum-rate and outage probability are investigated,and the closed-form expressions of the latter for DF and AF protocols are *** and simulation results are conducted to verify the validity of the theoretical analysis,in which we can see that the NOMA based DF relaying is better than the NOMA based AF relaying and other existing NOMA-based cooperative communication schemes.

关键词： non-orthogonal multiple access(NOMA) decode-and-forward(DF) amplify-and-forward(AF) relay selection ergodic sum-rate outage probability

Application of Exp-Function Method to Discrete Nonlinear Schrdinger Lattice Equation with Symbolic Computation

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Communications in Theoretical Physics 2008年第12期50卷 1279-1282页

作者： ji jie College of Statistics and Mathematics Zhejiang Gongshang University Hangzhou 310018 China

In this paper, we present an extended Exp-function method to differential-difference equation（s）. With the help of symbolic computation, we solve discrete nonlinear Schrodinger lattice as an example, and obtain a se... 详细信息

关键词： Exp-function solutions discrete nonlinear SchrSdinger lattice equation

Roles of the ocular pressure, pressure-sensitive ion channel, and elasticity in pressure-induced retinal diseases

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Neural Regeneration Research 2021年第1期16卷 68-72页

作者： ji-jie Pang Department of Ophthalmology Baylor College of MedicineHoustonTXUSA

The intraocular pressure inside the human eye maintains 10–21 mmHg above the atmospheric *** of intraocular pressure is highly correlated with the retinopathy in glaucoma,and changes in the exterior pressure during mountain hiking,air traveling,and diving may also induce vision decline and *** pathophysiological mechanism of these pressure-induced retinal disorders has not been completely *** neurons express pressure-sensitive channels intrinsically sensitive to pressure and membrane stretch,such as the transient receptor potential channel(TRP)family permeable to Ca^2+and Na^+and the two-pore domain K channel *** data have shown that pressure excites the primate retinal bipolar cell by opening TRP vanilloid 4 to mediate transient depolarizing currents,and TRP vanilloid 4 agonists enhance the membrane excitability of primate retinal ganglion *** eyeball wall is constructed primarily by the sclera and cornea of low elasticity,and the flow rate of the aqueous humor and intraocular pressure both fluctuate,but the mathematical relationship between the ocular elasticity,aqueous humor volume,and intraocular pressure has not been *** review will briefly review recent literature on the pressure-related retinal pathophysiology in glaucoma and other pressure-induced retinal disorders,the elasticity of ocular tissues,and pressure-sensitive cation channels in retinal *** data support the global volume and the elasticity and thickness of the sclera and cornea as variables to affect the intraocular pressure level like the volume of the aqueous *** results also suggest some potential routes for TRPs to mediate retinal ganglion cell dysfunction:TRP opening upon intraocular pressure elevation and membrane stretch,enhancing glutamate release from bipolar cells,increasing intracellular Na^+,Ca^2+concentration in retinal ganglion cells and extracellular glutamate concentration,inactivating voltage-ga

关键词： glaucoma ocular elasticity patch-clamp pressure-sensitive ion channel retina retinal bipolar cell retinal ganglion cell TRP