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Experimental Investigation of Crystal Structure of Zr 0.98 NiGe 2.94 and Phase Equilibria in Zr-Ni-Ge System

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Journal of Harbin Institute of Technology(New Series) 2023年第4期30卷 1-14页

作者： Zhengyang Wang Weijing Zeng Hong Zhang huashan liu School of Materials Science and Engineering Central South UniversityChangsha 410083China Key Lab of Non-Ferrous Metal Materials Science and Engineering Ministry of EducationCentral South UniversityChangsha 410083China

Based on the results of electron probe microanalysis(EPMA)and X-ray diffraction(XRD),the isothermal sections of Zr-Ni-Ge ternary system at 973 K and 1173 K were constructed through alloy sampling *** is worth noting that the crystallographic information of the formerly reportedτ2(Zr_(0.98)NiGe_(2.94))was determined,which belongs to the space group Pbcm(No.57).Besides the formerly reported ternary compounds,τ1(Zr_(6)Ni_(16)Ge_(7)),τ_(2)(Zr_(0.98)NiGe_(2.94)),τ_(3)(Zr_(3)Ni_(4)Ge_(4)),τ_(4)(ZrNiGe)andτ_(5)(Zr_(2)Ni_(0.54)Ge_(0.46)),a new ternary phase namedτ_(6)with the composition of Zr_(39)Ni_(18)Ge_(43)was primarily detected in this *** addition,an invariant reaction Ni_(5)Ge_(3)+τ_(4)τ_(1)+τ_(3)between 973 K and 1173 K was deduced.

关键词： Zr-Ni-Ge system phase diagram isothermal section crystal structure Zr_(0.98)NiGe_(2.94)

Thermodynamical and topological properties of metastable Fe_(3)Sn

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npj Computational Materials 2022年第1期8卷 2373-2384页

作者： Chen Shen Ilias Samathrakis Kun Hu Harish K.Singh Nuno Fortunato huashan liu Oliver Gutfleisch Hongbin Zhang School of Materials Science Technical University DarmstadtOtto-Berndt-Straße 3Darmstadt64287Germany School of Materials Science and Engineering Central South UniversityLushan South Road 932410083ChangshaChina

The Fe–Sn-based kagome compounds attract intensive attention due to its attractive topological transport and rich magnetic *** experimental data,first-principles calculations,and Calphad assessment,thermodynamic and topological transport properties of the Fe–Sn system were *** functional theory(DFT)calculations were performed to evaluate the intermetallics’finite-temperature heat capacity(C_(p)).A consistent thermodynamic assessment of the Fe–Sn phase diagram was achieved by using the experimental and DFT results,together with all available data from previous ***,we report that the metastable phase Fe_(3)Sn was introduced into the current metastable phase diagram,and corrected phase locations of Fe_(5)Sn_(3)and Fe_(3)Sn_(2)under the newly measured corrected temperature ***,the anomalous Hall conductivity and anomalous Nernst conductivity of Fe_(3)Sn were calculated,with magnetization directions and doping considered as perturbations to tune such transport *** was observed that the enhanced anomalous Hall and Nernst conductivities originate from the combination of nodal lines and small gap areas that can be tuned by doping Mn at Fe sites and varying magnetization direction.

关键词： intermetallics metastable magnetization

Zero-Sequence Current Suppression Strategy for Open-End Winding Permanent Magnet Synchronous Motor Based on Model Predictive Control

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Journal of Donghua University(English Edition) 2020年第4期37卷 286-292页

作者： liu huashan LI Jie YAO Fei College of Information Science and Technology Donghua UniversityShanghai 201620China Engineering Research Center of Digitized Textile&Apparel Technology Ministry of EducationShanghai 201620China

Compared with the traditional three-phase star connection winding,the open-end winding permanent magnet synchronous motor(OW-PMSM)system with a common direct current(DC)bus has a zero-sequence circuit,which makes the common-mode voltage and the back electromotive force(EMF)harmonic generated by the inverters produce the zero-sequence current in the zero-sequence circuit,and the zero-sequence current has great influence on the operation efficiency and stability of the motor control system.A zero-sequence current suppression strategy is presented based on model predictive current control for *** the mathematical model of OW-PMSM to establish the predictive model and the zero-sequence circuit model,the common-mode voltage under different voltage vector combinations is fully considered during vector selection and action time *** zero-sequence loop constraints are established,so as to suppress the zero-sequence *** the end,the control strategy proposed in this paper is verified by simulation experiments.

关键词： open-end winding permanent magnet synchronous motor(OW-PMSM) zero-sequence current harmonic model predictive current control common-mode voltage

Adaptive Neural Network Control for Euler-Lagrangian Systems with Uncertainties

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Journal of Donghua University(English Edition) 2022年第5期39卷 485-489页

作者： CHENG Xin LU Wenke liu huashan College of Information Science and Technology Donghua UniversityShanghai 201620China Engineering Research Center of Digitized Textile and Fashion Technology Ministry of EducationShanghai 201620China

An adaptive controller involving a neural network(NN)compensator is proposed to resist the uncertainties in the Euler-Lagrangian system(ELS).Firstly,a proportional-differential(PD)control law is designed for the nominal ***,the uncertainties including model error and external disturbance are separated from the closed-loop ***,an adaptive NN compensator based on the online training mode is proposed to eliminate the adverse effect of the *** addition,the stability of the closed-loop system is proved by Lyapunov ***,the effectiveness of the proposed approach is verified on a two-degree-of-freedom robot manipulator.

关键词： adaptive control neural network(NN) uncertainty compensator Euler-Lagrangian system(ELS)

ARTICLE OPEN Mutant KRAS triggers functional reprogramming of tumor-associated macrophages in colorectal cancer

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Signal Transduction and Targeted Therapy 2021年第5期6卷 1498-1510页

作者： huashan liu Zhenxing Liang Chi Zhou Ziwei Zeng Fengwei Wang Tuo Hu Xiaowen He Xiaojian Wu Xianrui Wu Ping Lan Department of Coloreaal Surgery The Sixth Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdongChina Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases The Sixth Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdongChina Clinical Innovation Department Guangzhou Regenerative Medicine and Health Guangdong LaboratoryGuangzhouChina Department of Colorectal Surgery Sun Yat-sen University Cancer CenterGuangzhouChina State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer MedicineSun Yat-sen University Cancer CenterGuangzhouGuangdongChina

Oncogenic KRAS has been previously identified to act in a cell-intrinsic manner to modulate multiple biological functions of colorectal cancer(CRC).Here,we demonstrate a cell-extrinsic role of KRAS,where KRAS engages with the tumor microenvironment by functional reprogramming of tumor-associated macrophages(TAMs).In human CRC specimens,mutant KRAS positively correlates with the presence of *** activated KRAS in tumor cells reprograms macrophages to a TAM-like phenotype via a combination effect of tumor-derived CSF2 and *** turn,KRAS-reprogrammed macrophages were shown to not only promote tumor progression but also induce the resistance of tumor cells to cetuximab ***,KRAS drives the production of CSF2 and lactate in tumor cells by stabilizing hypoxia-inducible factor-la(HIF-1a),a transcription factor that controls the expression of CSF2 and glycolytic *** KRAS increased the production of reactive oxygen species,an inhibitor of prolyl hydroxylase activity which decreases HIF-1a hydroxylation,leading to enhanced HIF-1a *** cell-extrinsic mechanism awards KRAS a critical role in engineering a permissive microenvironment to promote tumor malignancy,and may present new insights on potential therapeutic defense strategies against mutant KRAS tumors.

关键词： KRAS colorectal programming

Incidence and risk factors for incisional surgical site infection in patients with Crohn’s disease undergoing bowel resection

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Gastroenterology Report 2018年第3期6卷 189-194页

作者： Tuo Hu Xianrui Wu Jiancong Hu Yufeng Chen huashan liu Chi Zhou Xiaowen He Min Zhi Xiaojian Wu Ping Lan Department of Colorectal Surgery The Sixth Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdongChina Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases Guangdong Institute of GastroenterologyGuangzhouGuangdongChina Department of Gastroenterology/Hepatology The Sixth Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdongChina

Background:Patients with Crohn’s disease(CD)are often reported to be at a high risk for incisional surgical site infection(SSI).The aim of this study was to identify the risk factors associated with post-operative incisional SSI in CD patients after bowel ***:CD patients undergoing bowel resection between 2007 and 2015 were *** and clinical features related to post-operative incisional SSI were analysed using both univariate and multivariate logistical ***:Of all eligible patients(n=159),123(77.4%)were male,with a mean age at surgery of 33.4611.8 years.A total of 35(22.0%)CD patients developed post-operative incisional ***-operative incisional SSI was more likely to happen in patients who had penetrating type of disease(P=0.018),underwent bowel resection for the indication of chronic fistula(P=0.005)and had an intra-operative finding of fistula(P=0.001).A greater proportion of patients with post-operative incisional SSI were found to have anemia(P=0.019)but elevated levels of white blood cells(P=0.027),neutrophils(P=0.006)as well as an elevated percentage of neutrophils(P=0.005).Multivariate logistic regression analysis showed that anemia(odds ratio[OR]:3.31,95%confidence interval[CI]:1.05-10.46,P=0.041),an elevated percentage of neutrophils(OR:2.85,95%CI:1.23-6.59,P=0.014)and an intra-operative finding of fistula(OR:3.76,95%CI:1.53-9.21,P=0.004)were significantly associated with the risk for post-operative incisional ***:Anemia,elevated percentage of neutrophils and intra-operative finding of fistula are predictors for the development of post-operative incisional SSI in CD patients undergoing bowel *** pre-operative nutrition status and low inflammatory status may lessen the incidence of post-operative incisional SSI.

关键词： Crohn’s disease incisional surgical site infection risk factors bowel resection

Prudent Policy Gradient with Auxiliary Actor in Multi-degree-of-freedom Robotic Tasks

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Prudent Policy Gradient with Auxiliary Actor in Multi-degree...

第40届中国控制会议

作者： Xiangjian Li huashan liu Xin Cheng Menghua Dong College of Information Science and Technology Donghua University Engineering Research Center of Digitized Textile and Apparel Technology Ministry of Education

The overestimation bias caused by the function approximation error is a common problem of the value-based reinforcement learning algorithms. A clipped Double Q-learning method and delayed policy updates are adopted by Twin Delayed Deep Deterministic policy gradient（TD3） algorithm to reduce the impact of this problem. Although TD3 brings some feasibility,the problem still has not been solved ideally. Thus, based on TD3 an novel algorithm named as Prudent Policy Gradient（PPG）is proposed, where an auxiliary actor is used to prevent actor from selecting exceeding actions and makes the agent’s behavior more prudent. This allows the proposed PPG to find a more efficient and stable policy. The experimental results illustrate that the proposed PPG outperforms TD3 in robotic tasks of several MuJoCo benchmarks and path explorations.

关键词： Deep reinforcement learning Path exploration Auxiliary actor Robot task

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道德推理与道德行为关系的元分析

心理学报 2014年第8期46卷 1192-1207页

作者：吴鹏刘华山湖北大学教育学院心理学系武汉430062 华中师范大学心理学院青少年网络心理与行为教育部重点实验室武汉430079

目前道德心理学中存在对道德推理作用的质疑,这一质疑源自哲学领域的著名争论。从经典道德心理学理论来说,道德推理应该是道德行为的重要决定因素,但新近的观点则否定这一重要作用。本研究采用元分析技术探讨道德推理与道德行为的关系... 详细信息

目前道德心理学中存在对道德推理作用的质疑,这一质疑源自哲学领域的著名争论。从经典道德心理学理论来说,道德推理应该是道德行为的重要决定因素,但新近的观点则否定这一重要作用。本研究采用元分析技术探讨道德推理与道德行为的关系。通过文献搜索与检查,获得了50项研究和83个独立效应量,共包含16738名被试。检验表明发表偏差不会影响元分析的结果,选择随机效应模型是准确的。通过随机效应模型的元分析表明,道德推理与道德的行为有显著的正相关,与不道德的行为有显著的负相关。调节效应分析表明,道德推理测量工具的类型会影响道德推理与道德行为的关系,被试年龄阶段会影响道德推理与不道德行为的关系。这些结果肯定了道德推理的作用,也强调了研究过程中要关注测量工具的类型,指出了需要开发更全面的道德推理测量工具。

关键词：道德推理道德行为元分析调节效应

道德情绪对网络助人行为的影响——道德推理的中介作用

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心理学报 2017年第12期49卷 1559-1569页

作者：吴鹏范晶刘华山湖北大学教育学院心理学系武汉430062 华中师范大学心理学院武汉430079

对道德情绪与道德推理在道德行为中的作用,道德心理学研究者还存在一定的争议。传统道德心理学理论认为道德推理应该起重要作用。最新的道德心理模型则认为道德情绪也起重要作用,但在情绪与推理的作用大小上存在争议。实验1通过情绪启... 详细信息

对道德情绪与道德推理在道德行为中的作用,道德心理学研究者还存在一定的争议。传统道德心理学理论认为道德推理应该起重要作用。最新的道德心理模型则认为道德情绪也起重要作用,但在情绪与推理的作用大小上存在争议。实验1通过情绪启动与电子邮件求助的研究范式,探讨同情、内疚情绪对网络助人行为的影响,结果表明同情与内疚情绪可以显著激发个体的网络助人行为。实验2探讨道德情绪影响网络助人行为的机制,即道德推理在道德情绪对网络助人行为影响的中介作用,结果表明道德推理可以部分中介道德情绪对网络助人行为的影响。上述结果表明道德情绪对网络助人行为的直接影响及道德推理的部分中介作用,不支持道德动机社会直觉模型、支持道德双加工模型。

关键词：道德情绪道德推理网络助人行为中介效应