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Corrigendum to “The development of a sensitive fluorescent protein-based transcript reporter for high throughput screening of negative modulators of lncRNAs” [Genes & Diseases 5 (2018) 62–74]

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Genes & Diseases 2023年第2期10卷 627-629页

作者： Zongyue Zeng Bo huang shifeng huang Ruyi Zhang Shujuan Yan Xinyi Yu Yi Shu Chen Zhao Jiayan Lei Wenwen Zhang Chao Yang Ke Wu Ying Wu Liping An Xiaojuan Ji Cheng Gong Chengfu Yuan Linghuan Zhang Wei Liu Yixiao Feng Bo Zhang Zhengyu Dai Yi Shen Xi Wang Wenping Luo Rex C. Haydon Hue H. Luu Lan Zhou Russell R. Reid Tong-Chuan He Xingye Wu Ministry of Education Key Laboratory of Diagnostic Medicine and School of Laboratory Medicine Chongqing Medical UniversityChongqing 400016China Molecular Oncology Laboratory Department of Orthopaedic Surgery and Rehabilitation MedicineThe University of Chicago Medical CenterChicagoIL 60637USA Department of Clinical Laboratory Medicine The Second Affiliated Hospital of Nanchang UniversityNanchang 330006China Departments of Clinical Laboratory Medicine General SurgeryOrthopedic SurgeryNephrologyand CardiologyThe First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China The Children's Hospital Chongqing Medical UniversityChongqing 400014China Department of Laboratory Medicine and Clinical Diagnostics The Affiliated Yantai HospitalBinzhou Medical UniversityYantai 264100China Department of Immunology and Microbiology Beijing University of Chinese MedicineBeijing 100029China Key Laboratory of Orthopaedic Surgery of Gansu Province and the Department of Orthopaedic Surgery The Second Hospital of Lanzhou UniversityLanzhou 730030China Department of Surgery The Affiliated Zhongnan Hospital of Wuhan UniversityWuhan 430071China Department of Biochemistry and Molecular Biology China Three Gorges University School of MedicineYichang 443002China Department of Orthopaedic Surgery Chongqing Hospital of Traditional Chinese MedicineChongqing 400021China Department of Orthopaedic Surgery Xiangya Second Hospital of Central South UniversityChangsha 410011China Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences Chongqing 401147China The Affiliated Hospital of Stomatology of Chongqing Medical University Chongqing 401147China Department of Surgery Laboratory of Craniofacial Biology and DevelopmentSection of Plastic SurgeryThe University of Chicago Medical CenterChicagoIL 60637USA

The authors regret having an image assembly error in Figure 5Ca,in which the image for the "Oh dBiFP-AdRFp"group was erroneously duplicated with an overlapping image from the"36h BiFP dBIFP-AdR-simH19"*** confirm the error is restricted to the image assembly,and the underlying data and conclusions are correct and *** authors would like to apologize for any inconvenience caused.

关键词： image Figure unchanged

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重症监护病房患者的睡眠状况及其影响因素分析

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世界睡眠医学杂志 2022年第7期9卷 1214-1215页

作者：黄世凤福建医科大学附属第一医院重症医学科福州350001

目的:观察重症监护病房内相关患者实际睡眠情况,判断影响患者睡眠质量的因素,为提升患者睡眠质量提供科学依据。方法:选取2020年1月至2021年6月福建医科大学附属第一医院收治的重症监护病房(ICU)患者126例作为观察组,另选取普通病房患者... 详细信息

目的:观察重症监护病房内相关患者实际睡眠情况,判断影响患者睡眠质量的因素,为提升患者睡眠质量提供科学依据。方法:选取2020年1月至2021年6月福建医科大学附属第一医院收治的重症监护病房(ICU)患者126例作为观察组,另选取普通病房患者126例作为对照组。分别采用基础睡眠评估量表与重症监护病房睡眠评估量表对2组患者进行检测评估,探索影响ICU患者睡眠质量的因素。结果:对照组患者基础睡眠评估量表评分高于观察组(P<0.05),126例ICU患者有睡眠障碍的100例,占79.4%,睡眠正常的有26例,占20.6%;利用二元Logistic回归分析,明确和重症监护病房患者睡眠质量相关的因素有4项,即医护人员的影响、噪声影响、身体不舒适状态影响与担忧情绪。结论:要想保障重症病房患者睡眠质量,需要医护工作者充分地投入耐心与关怀,优化病房环境,以免出现医护人员干扰情况,规避诸多影响患者睡眠质量的因素产生,给其提供良好的治疗条件。

关键词：重症监护病房睡眠状况影响内容睡眠评估量表

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Influence of the prestressed layer on spherical transducer in sound radiation performance

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Journal of Advanced Dielectrics 2022年第6期12卷 32-39页

作者： Xiaofang Zhang Xiujuan Lin Rui Guo Changhong Yang Hui Zhao Mingyu Zhang Yan Wang Xin Cheng shifeng huang Shandong Provincial Key Laboratory of Preparation and Measurement of Building Materials University of Jinan 336 Nanxinzhuang West RoadJinanShandong 250022P.R.China Underwater Acoustic Transducer Lab Shanghai Marine Electronic Equipment Research Institute Shanghai 201108P.R.China

To improve the acoustic radiation performance of the spherical transducer,a prestressed layer is formed in the transducer through fiber *** influence of the prestressed layer on the transducer is studied from the effects of the radial prestress(Tr)and acoustic impedance,***,a theoretical estimation of Tr is established with a thin shell approximation of the prestressed ***,the acoustic impedance is measured to evaluate the efficiency of sound energy transmission within the prestressed ***,the ideal effects of Tr on the sound radiation performances of the transducer are analyzed through finite element analysis(FEA).Finally,four spherical transducers are fabricated and tested to investigate their dependence of actual properties on the prestressed *** results show that with the growth of Tr,the acoustic impedance of the prestressed layer grows,mitigating the enormous impedance mismatch between the piezoelectric ceramic and water,while increasing attenuation of the acoustic energy,resulting in a peak value of the maximum transmitting voltage response(TVRmax)at 1.18 *** maximum drive voltage increases with Tr,leading to a steady growth of the maximum transmitting sound level(SLmax),with a noticeable ascend of 3.9 dB at a 3.44 MPa *** is a strong credibility that the prestressed layer could improve the sound radiation performance of the spherical transducer.

关键词： Radial prestress acoustic impedance spherical transducers transmission voltage response transmission sound level

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脂肪因子在慢性肾脏病动脉粥样硬化中作用的研究进展

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右江医学 2023年第2期51卷 97-101页

作者：黄石凤王洁右江民族医学院附属医院肾内科广西百色533000 右江民族医学院研究生学院广西百色533000

心血管并发症是慢性肾脏病(chronic kidney disease,CKD)首要死亡原因,动脉粥样硬化(atherosclerosis,AS)对CKD患者心血管事件发生的早期预测和干预起着重要作用。脂肪组织被认为是一种活跃的内分泌器官,可分泌多种脂肪因子。近年研究发... 详细信息

心血管并发症是慢性肾脏病(chronic kidney disease,CKD)首要死亡原因,动脉粥样硬化(atherosclerosis,AS)对CKD患者心血管事件发生的早期预测和干预起着重要作用。脂肪组织被认为是一种活跃的内分泌器官,可分泌多种脂肪因子。近年研究发现,多个脂肪因子成员在AS的发生机制中具有重要调节作用。肾脏是多个脂肪因子清除的场所,CKD患者肾脏清除能力下降及存在着脂代谢异常、微炎症状态、胰岛素抵抗、钙磷代谢紊乱等一个或多个合并症可导致体内的脂肪因子谱异常。当体内促钙脂肪因子和抑钙脂肪因子失衡时会引起一系列反应影响血管壁状态,影响AS的发生发展。该文旨在讨论几个具有代表性的脂肪因子在CKD患者合并AS中的作用。

关键词：慢性肾脏病动脉粥样硬化脂肪因子

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Corrigendum to “Characterization of the essential role of bone morphogenetic protein 9 (BMP9) in osteogenic differentiation of mesenchymal stem cells (MSCs) through RNA interference” [Genes & Diseases 5(2018):172–184]

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Genes & Diseases 2023年第2期10卷 632-637页

作者： Shujuan Yan Ruyi Zhang Ke Wu Jing Cui shifeng huang Xiaojuan Ji Liping An Chengfu Yuan Cheng Gong Linghuan Zhang Wei Liu Yixiao Feng Bo Zhang Zhengyu Dai Yi Shen Xi Wang Wenping Luo Bo Liu Rex C. Haydon Michael J. Lee Russell R. Reid Jennifer Moriatis Wolf Qiong Shi Hue H. Luu Tong-Chuan He Yaguang Weng Ministry of Education Key Laboratory of Diagnostic Medicine and School of Laboratory Medicine Chongqing Medical UniversityChongqing 400016China Molecular Oncology Laboratory Department of Orthopaedic Surgery and Rehabilitation MedicineThe University of Chicago Medical CenterChicagoIL 60637USA The School of Pharmacy and the Affiliated Hospitals of Chongqing Medical University Chongqing 400016China Key Laboratory of Orthopaedic Surgery of Gansu Province and the Department of Orthopaedic Surgery The Second Hospital of Lanzhou UniversityLanzhouGansu 730030China Department of Biochemistry and Molecular Biology China Three Gorges University School of MedicineYichangHubei 443002China Department of Surgery The Affiliated Zhongnan Hospital of Wuhan UniversityWuhanHubei 430071China Department of Orthopaedic Surgery Chongqing Hospital of Traditional Chinese MedicineChongqing 400021China Department of Orthopaedic Surgery Xiangya Second Hospital of Central South UniversityChangshaHunan 410011China Department of Surgery Laboratory of Craniofacial Biology and DevelopmentSection of Plastic SurgeryThe University of Chicago Medical CenterChicagoIL 60637USA

The authors regret having several image assembly ***,in Figure 3A panel b,the image for "AdsimB9-4 only"group was erroneously duplicated with an overlapping image from the"AdRFp"group;and the image for"AdsimB9-1+BMP9"groupwas erroneouslyduplicatedwithan overlapping image from"AdsimB9-8+BMP9"*** Figure 4Apanel a,the images for"BMP9"group and "BMP9+simB9-4"group were erroneously duplicated with an overlapping image from"simB9-4"*** Figure 5A,the image for"BMP9+simB9-4/Day3"group was erroneously duplicated with an overlapping image from"BMP9+simB9-7/Day3"group;and the image for"BMP9+simB9-4/Day5"group was erroneously duplicated with an overlapping image from an unrelated *** Figure 6B,the image for"BMP9+simB9-7/Day 11"group was erroneously duplicated with an overlapping image from the"BMP9+simB9-4/Day 11"group.

关键词： Figure BMP9 Cor

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碳纤维硫铝酸盐水泥基机敏复合材料

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复合材料学报 2005年第6期22卷 114-119页

作者：王守德黄世峰陈文程新武汉理工大学材料学院 430070 济南大学材料学院 250022

采用压制成型方法制备了碳纤维硫铝酸盐水泥基复合材料(Carbon Fiber Reinforced SulphoaluminateCement,简称CFRS)。用XRD和孔结构分析仪对复合材料的物相和孔径与孔体积的关系进行了分析,研究了不同碳纤维掺量对复合材料在单调压应力... 详细信息

采用压制成型方法制备了碳纤维硫铝酸盐水泥基复合材料(Carbon Fiber Reinforced SulphoaluminateCement,简称CFRS)。用XRD和孔结构分析仪对复合材料的物相和孔径与孔体积的关系进行了分析,研究了不同碳纤维掺量对复合材料在单调压应力和循环压应力下的机敏性能的影响。XRD和孔结构分析研究结果表明,压制成形的试样水化14天硫铝酸盐水泥水化仍不完全,试样结构致密,孔隙率较小,孔径基本小于0.9μm;单调压应力下机敏测试性能表明,碳纤维掺量为0.3%和0.5%的CFRS试样电容变化率与压应力近似成线性关系,机敏性能较好;循环压应力下碳纤维掺量为0.7%的CFRS试样电容变化率与循环压应力成一一对应关系,表现出较好的机敏特性。

关键词：碳纤维硫铝酸盐水泥机敏性能介电常数

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传感器测试FRP约束混凝土轴压短柱的核心区应力

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复合材料学报 2015年第2期32卷 549-556页

作者：彭亚萍张颖黄世峰上海应用技术学院城市建设与安全工程学院上海201418 山东大卫国际建筑设计有限公司济南250002 济南大学土木建筑学院济南250022

提出了一种使用水泥基压电陶瓷传感器测试混凝土轴压短柱应力的新方法。将压电传感器埋入混凝土矩形短柱核心区,测试了纤维增强复合材料约束前后混凝土短柱的轴向动态疲劳载荷,建立了传感器输出信号与混凝土短柱核心区应力之间的数值模... 详细信息

提出了一种使用水泥基压电陶瓷传感器测试混凝土轴压短柱应力的新方法。将压电传感器埋入混凝土矩形短柱核心区,测试了纤维增强复合材料约束前后混凝土短柱的轴向动态疲劳载荷,建立了传感器输出信号与混凝土短柱核心区应力之间的数值模型,并将理论计算应力值与由模型推导出的应力值进行对比。结果表明:模型推导应力值与理论计算应力值基本吻合,验证了使用压电传感器测试动态载荷作用下混凝土短柱应力这一新方法的可行性。

关键词：纤维增强复合材料约束混凝土短柱应力水泥基压电陶瓷传感器

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Breast cancer development and progression:Risk factors,cancer stem cells,signaling pathways,genomics,and molecular pathogenesis

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Genes & Diseases 2018年第3期5卷 77-106页

作者： Yixiao Feng Mia Spezia shifeng huang Chengfu Yuan Zongyue Zeng Linghuan Zhang Xiaojuan Ji Wei Liu Bo huang Wenping Luo Bo Liu Yan Lei Scott Du Akhila Vuppalapati Hue H.Luu Rex C.Haydon Tong-Chuan He Guosheng Ren Chongqing Key Laboratory of Molecular Oncology and Epigenetics Departments of General SurgeryClinical Laboratory MedicineOrthopaedic SurgeryPlastic Surgery and Burnand OtolaryngologyHead and Neck SurgeryThe First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Molecular Oncology Laboratory Department of Orthopaedic Surgery and Rehabilitation MedicineThe University of Chicago Medical CenterChicagoIL 60637USA Department of Biochemistry and Molecular Biology China Three Gorges University School of MedicineYichang 443002China Ministry of Education Key Laboratory of Diagnostic Medicine and School of Laboratory Medicine Chongqing Medical UniversityChongqing 400016China Stem Cell Biology and Therapy Laboratory Ministry of Education Key Laboratory of Child Development and DisordersThe Children’s Hospital of Chongqing Medical UniversityChongqing 400014China Department of Clinical Laboratory Medicine The Second Affiliated Hospital of Nanchang UniversityNanchang 330006China Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences The Affiliated Hospital of StomatologyChongqing Medical UniversityChongqing 401147China Student Inquiry Research Program Illinois Mathematics and Science Academy(IMSA)AuroraIL 60506USA

As the most commonly occurring cancer in women worldwide,breast cancer poses a formidable public health challenge on a global *** cancer consists of a group of biologically and molecularly heterogeneous diseases originated from the *** the risk factors associated with this cancer varies with respect to other cancers,genetic predisposition,most notably mutations in BRCA1 or BRCA2 gene,is an important causative factor for this *** cancers can begin in different areas of the breast,such as the ducts,the lobules,or the tissue in *** the large group of diverse breast carcinomas,there are various denoted types of breast cancer based on their invasiveness relative to the primary tumor *** is important to distinguish between the various subtypes because they have different prognoses and treatment *** there are remarkable parallels between normal development and breast cancer progression at the molecular level,it has been postulated that breast cancer may be derived from mammary cancer stem *** breast development and mammary stem cells are regulated by several signaling pathways,such as estrogen receptors(ERs),HER2,and Wnt/b-catenin signaling pathways,which control stem cell proliferation,cell death,cell differentiation,and cell ***,emerging evidence indicates that epigenetic regulations and noncoding RNAs may play important roles in breast cancer development and may contribute to the heterogeneity and metastatic aspects of breast cancer,especially for triple-negative breast *** review provides a comprehensive survey of the molecular,cellular and genetic aspects of breast cancer.

关键词： BRCA1/2 Breast cancer Cancer stem cells Estrogen receptors HER2 Noncoding RNAs Triple-negative breast cancer Tumor heterogeneity

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六关节工业机器人TCP标定模型研究与算法改进

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机械工程学报 2019年第11期55卷 186-196页

作者：周星黄石峰朱志红佛山智能装备技术研究院佛山528225 华中科技大学国家数控系统工程技术研究中心武汉430074

研究了六关节工业机器人工具坐标系原点TCP的标定原理,提出了TCP标定的解析化模型和几何模型,并对标定误差来源进行了综合性分析,定量分析了标定点数和标定位姿对TCP标定精度的影响。在经典四点法标定的基础上,引入了误差阈值的概念,提... 详细信息

研究了六关节工业机器人工具坐标系原点TCP的标定原理,提出了TCP标定的解析化模型和几何模型,并对标定误差来源进行了综合性分析,定量分析了标定点数和标定位姿对TCP标定精度的影响。在经典四点法标定的基础上,引入了误差阈值的概念,提出一种改进的“五点选优TCP标定算法”,并进行了仿真验证和实物验证。验证结果表明,提出的标定算法能够有效筛选出误差偏大的点,对标定精度能进一步提高,可靠性也得到了进一步保证。

关键词：六关节工业机器人 TCP标定标定点数标定位姿解析化模型与几何模型选优

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Nosocomial spread of imipenem-resistant Acinetobacter baumannii carrying OXA-23 gene with upstream ISAba1 in a Chinese hospital

Nosocomial spread of imipenem-resistant Acinetobacter bauman...

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中华医学会第七次全国中青年检验医学学术会议

作者：戴伟张莉萍曹炬 Sun Shan huang shifeng The First Affiliated Hospital of Chongqing Medical University

The present study was performed to investigate the molecular epidemiology of imipenem-resistant *** isolates recovered from a tertiary care teaching hospital in Chong Qing and to explore the responsible oxacillinases(...

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