检索结果-南通市图书馆

3-(9-芴甲氧羰基)四氢噻唑-2-硫酮的合成及其晶体结构

在线全文

学校读者我要写书评

暂无评论

化学学报 1998年第7期56卷 655-661页

作者：李叶芝郭纯孝胡学山杜莉萍黄化民吉林大学化学系长春130023

在吡啶存在下,由9-芴甲氧羰酰氯与四氢噻唑-2-硫酮反应得到3-(9-芴甲氧羰基)四氢噻唑-2-硫酮,产率为78.0%.用X射线衍射法测定晶体结构,属正交晶系,Pca2_1空间群,晶体学参数:α=0.9654(2),b=2.8032(1),c=0.6069(2)nm,Z=4.分子中的C=O与C=... 详细信息

在吡啶存在下,由9-芴甲氧羰酰氯与四氢噻唑-2-硫酮反应得到3-(9-芴甲氧羰基)四氢噻唑-2-硫酮,产率为78.0%.用X射线衍射法测定晶体结构,属正交晶系,Pca2_1空间群,晶体学参数:α=0.9654(2),b=2.8032(1),c=0.6069(2)nm,Z=4.分子中的C=O与C=S基团`处在C(3)-N-C(4)键的同侧,为顺式结构.用PM3分子轨道方法研究该化合物的电子结构、电荷和键序分布、前线轨道性质.

关键词：芴甲氧羰基四氢噻唑硫酮合成晶体结构 FmocTT

在线全文

学校读者我要写书评

暂无评论

析中职体育对学生心理健康的影响及发展模式

南京体育学院学报（自然科学版） 2011年第3期10卷 87-88,91页

作者：黄华敏易鹏武汉市交通学校湖北武汉430074 中国地质大学江城学院湖北武汉430200

在经济和社会飞速发展的今天,我国学生心理健康问题越来越突出,中职学生也不例外。《体育与健康课程标准》中,将体育学习目标分为运动参与、运动技能、身体健康、心理健康和社会适应五个学习领域,并将每一个学习领域细分为若干个水平目... 详细信息

在经济和社会飞速发展的今天,我国学生心理健康问题越来越突出,中职学生也不例外。《体育与健康课程标准》中,将体育学习目标分为运动参与、运动技能、身体健康、心理健康和社会适应五个学习领域,并将每一个学习领域细分为若干个水平目标。《体育与健康课程标准》把心理健康作为重要的学习领域,第一次明确地写入学校体育课程教学目标,体育锻炼促进学生心理健康的功能日益受到关注。文中通过中职学生的心理现状、体育对心理健康的教育功能、现阶段中职体育的授课模式等几个方面进行分析,探讨中职体育教学改革发展的模式。

关键词：中职体育心理健康

Engineering high-performance chemiluminescent probes via enzymatic pocket targeting: high-throughput screening for ultralong afterglow imaging of orthotopic hepatocellular carcinoma

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2025年

作者： Shuai huang Shuaige Bai Ting Luo Bin Feng min Liu Fan Zheng Shuang huang Yanpeng Fang Dan Ding Wenbin Zeng Xiangya School of Pharmaceutical Sciences Central South University College of Life Sciences Nankai University

Hepatocellular carcinoma （HCC） is a highly aggressive liver malignancy and the main form of liver cancer. Early diagnosis and treatment of HCC can effectively reduce mortality. Carboxylesterase （CE）-specific detection and imaging can be used for early diagnosis and image-guided surgical of HCC. However, traditional optical probes suffer from poor selectivity and low imaging signal-to-noise ratio. Here, we have constructed a series of chemiluminescent probes for carboxylesterase detection based on the strategy of enzymatic pocket-oriented steric tailoring techniques. The probes with different unique and excellent properties have been obtained through the structure-based steric hindrance adjustment on the recognition site. Here, CE-2 has been successfully used for high-throughput screening of rapid carboxylesterase inhibitors due to its extremely low detection limit (2.5×10-4U mL-1) and fast recognition ability. CE-3 has been successfully used for image-guided surgery of orthotopic hepatocellular carcinoma due to its ultra-long chemiluminescence imaging （over 12 h） of hepatocellular carcinoma. This study may promote advances in the rapid detection and screening of inhibitory drugs for CE and the field of surgical navigation in HCC.

关键词：

Advanced Functional Electromagnetic Shielding Materials:A Review Based on Micro‑Nano Structure Interface Control of Biomass Cell Walls

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Nano-Micro Letters 2025年第1期17卷 98-134页

作者： Yang Shi mingjun Wu Shengbo Ge Jianzhang Li Anoud Saud Alshammari Jing Luo Mohammed A.Amin hua Qiu Jinxuan Jiang Yazeed M.Asiri Runzhou huang hua Hou Zeinhom M.El‑Bahy Zhanhu Guo Chong Jia Kaimeng Xu Xiangmeng Chen Co‑Innovation Center of Efficient Processing and Utilization of Forest Resources College of Materials Science and EngineeringNanjing Forestry UniversityNanjing 210037People’s Republic of China State Key Laboratory of Efficient Production of Forest Resourced Beijing Forestry UniversityQinghua East Road 35Haidian DistrictBeijing 100083People’s Republic of China Department of Physics Faculty of Sciences‑ArarNorthern Border UniversityArar 91431Saudi Arabia Department of Chemistry College of ScienceTaif UniversityP.O.Box 1109921944 TaifSaudi Arabia Shaanxi Key Laboratory of Macromolecular Science and Technology School of Chemistry and Chemical EngineeringNorthwestern Polytechnical UniversityXi’anShaanxi 710072People’s Republic of China Integrated Composites Lab Department of Mechanical and Construction EngineeringNorthumbria UniversityNewcastle Upon Tyne NE18STUK College of Materials Science and Engineering Taiyuan University of Science and TechnologyTaiyuan 030024People’s Republic of China Department of Chemistry Faculty of ScienceAl-Azhar UniversityNasr CityCairo 11884Egypt Yunnan Provincial Key Laboratory of Wood Adhesives and Glued Products International Joint Research Center for Biomass MaterialsSouthwest Forestry UniversityKunming 650224People’s Republic of China School of Science Henan Agricultural UniversityZhengzhou 450002People’s Republic of China

Research efforts on electromagnetic interference(EMI)shielding materials have begun to converge on green and sustainable biomass *** materials offer numerous advantages such as being lightweight,porous,and *** to their porous nature,interfacial compatibility,and electrical conductivity,biomass materials hold significant potential as EMI shielding *** concerted efforts on the EMI shielding of biomass materials have been reported,this research area is still relatively new compared to traditional EMI shielding *** particular,a more comprehensive study and summary of the factors influencing biomass EMI shielding materials including the pore structure adjustment,preparation process,and micro-control would be *** preparation methods and characteristics of wood,bamboo,cellulose and lignin in EMI shielding field are critically discussed in this paper,and similar biomass EMI materials are summarized and *** composite methods and fillers of various biomass materials were *** paper also highlights the mechanism of EMI shielding as well as existing prospects and challenges for development trends in this field.

关键词： Biomass materials Electromagnetic interference shielding Micro-nano structure interface control Conductivity

Quickly obtaining densely dispersed coherent particles in steel matrix and its related mechanical property

在线全文

学校读者我要写书评

暂无评论

International Journal of minerals,Metallurgy and Materials 2025年第1期32卷 111-118页

作者： Xiaoxiao Wang Qingsong huang School of Chemical Engineering Sichuan UniversityChengdu 610065China

Densely distributed coherent nanoparticles(DCN)in steel matrix can enhance the work-hardening ability and ductility of steel *** the routes to this end can be generally classified into the liquid-solid route and the solid-solid ***,the formation of DCN structures in steel requires long processes and complex *** far,obtaining steel with coherent particle enhancement in a short time remains a bottleneck,and some necessary steps remain ***,we show a high-efficiency liquid-phase refining process reinforced by a dynamic magnetic ***-Y-Mn-O particles had an average size of around(3.53±1.21)nm and can be obtained in just around 180 *** small nanoparticles were coherent with the matrix,implying no accumulated dislocations between the particles and the steel *** findings have a potential application for improving material machining capacity,creep resistance,and radiation resistance.

关键词： ferritic steels coherent particles microstructure compression test work hardening

3-苄氧羰基四氢噻唑-2-硫酮的晶体结构与量子化学研究

在线全文

学校读者我要写书评

暂无评论

高等学校化学学报 1998年第7期19卷 1144-1147页

作者：李叶芝郭纯孝胡学山杜莉萍黄化民吉林大学化学系

苄氧羰酰氯与四氢噻唑－２－硫酮在三乙胺存在下反应生成了３－苄氧羰基四氢噻唑－２－硫酮．在甲醇中培养了标题化合物单晶，用Ｘ射线衍射法进行了结构表征．晶体结构属三斜晶系，Ｐ１空间群，晶体学参数：ａ＝０．６２７４（２）ｎｍ... 详细信息

苄氧羰酰氯与四氢噻唑－２－硫酮在三乙胺存在下反应生成了３－苄氧羰基四氢噻唑－２－硫酮．在甲醇中培养了标题化合物单晶，用Ｘ射线衍射法进行了结构表征．晶体结构属三斜晶系，Ｐ１空间群，晶体学参数：ａ＝０．６２７４（２）ｎｍ，ｂ＝０．７３４０（３）ｎｍ，ｃ＝１．２９７６（４）ｎｍ；α＝１００．７３（３）°，β＝９４．５３（３）°，γ＝１０３．２８（３）°，Ｚ＝２，Ｍμ＝４．３０ｃｍ－１．分子中的ＣＯ与ＣＳ基团处于Ｃ（４）—Ｎ—Ｃ（１）键的同侧，为顺式．用ＰＭ３分子轨道方法研究了该化合物的电子结构，得到电荷和键序分布以及前线轨道等性质．

关键词：苄氧羰基四氢噻唑硫酮晶体结构电子结构 ZTT

在线全文

学校读者我要写书评

暂无评论

降糖肽Aglycin的高效表达及活性鉴定

现代食品科技 2020年第4期36卷 143-149,219页

作者：黄敏华林静莲王蒙马毅王菊芳华南理工大学生物科学与工程学院广东广州510006

基于自组装肽ELK16能在大肠杆菌细胞内自聚集的特性,本研究将Aglycin通过一个内含肽Mxe GyrA与自组装肽连接,构建能在体外自剪切的重组表达载体pET30a-Aglycin-Mxe-PT-ELK16。将重组质粒转化大肠杆菌BL21(DE3)并进行蛋白表达条件的优化... 详细信息

基于自组装肽ELK16能在大肠杆菌细胞内自聚集的特性,本研究将Aglycin通过一个内含肽Mxe GyrA与自组装肽连接,构建能在体外自剪切的重组表达载体pET30a-Aglycin-Mxe-PT-ELK16。将重组质粒转化大肠杆菌BL21(DE3)并进行蛋白表达条件的优化,得到目的蛋白聚集体,随后对聚集体进行DTT切割条件的优化,经过进一步纯化最终可得到纯度为98.15%、产量为5.53mg/g菌体湿重的Aglycin肽。采用基因工程手段重组表达Aglycin的产量比目前化学提取方法提高了近100倍。此外,经体外实验证明,Aglycin对α-葡萄糖苷酶抑制的IC50(36.48μmol/L)比阿卡波糖(991.33μmol/L)低,说明Aglycin比阿卡波糖有更强的α-葡萄糖苷酶抑制活性,这进一步证明Aglycin有开发为α-葡萄糖苷酶抑制剂的潜力。

关键词：重组表达自组装肽大肠杆菌 α-葡萄糖苷酶抑制

Economic effect of China's carbon neutrality target under shared socioeconomic pathways

在线全文

学校读者我要写书评

暂无评论

Science China Earth Sciences 2025年第1期68卷 142-157页

作者： Zemiao LIU Xianjin huang Xinxian QI School of Geography and Ocean Science Nanjing University Key Laboratory of Carbon Neutrality and Territory Optimization Ministry of Natural Resources Frontiers Science Center for Critical Earth Material Cycling Nanjing University

Economic feasibility is crucial for achieving the carbon neutrality target. However, current integrated assessments often underestimate the economic impacts of mitigation policies due to the lack of consideration of their economic benefits. This study integrates a warming-labour productivity model with a typical integrated assessment model using shared socioeconomic pathways. It simulates China's economic development and carbon emission levels under both baseline and carbon-neutral policy scenarios, evaluating the economic costs and benefits of emission reduction policies aimed at achieving carbon neutrality. These findings reveal the following:(1) The economic costs of emission reduction policies are projected to peak between 2050 and 2060, ranging from 0.41% to 9.37% of total GDP in the baseline scenario, primarily due to increased energy prices and R&D investments. These costs are expected to decline rapidly after 2070.(2) China's carbon-neutral policies will mitigate global warming, with the economic benefits of mitigation projected to reach 5.65% to 17.24% of China's total GDP by 2100.(3) Lowcarbon scenarios SSP1 and SSP4 could significantly reduce initial economic costs and advance the onset of net economic gains to 2060. This integrated assessment confirms that China's carbon neutrality target offers substantial net economic benefits in the long term. To minimize initial economic costs, efforts should focus on enhancing consumption-side transitions, upgrading lowcarbon technologies, and adopting new energy sources.

关键词： Climate change China Carbon neutrality Economic effects Policy

同方期刊数据库

Tectonic modes of mantle convection and their implications for Earth's tectonic evolution based on three-dimensional numerical simulations

在线全文

学校读者我要写书评

暂无评论

Science China Earth Sciences 2025年第1期68卷 270-296页

作者： Song XIANG Jinshui huang Bingcheng WU School of Earth and Space Sciences University of Science and Technology of China CAS Center of Excellence in Comparative Planetary Studies

Five tectonic modes of mantle convection are obtained and analyzed with three-dimensional numerical models in a spherical shell domain. The five tectonic convective modes are non-plate mobile-lid, plate-like mobile-lid, episodic plate-like mobile-lid, episodic stagnant-lid, and stagnant-lid convective modes, respectively. The typical characteristics of these five tectonic modes and their numerical classification criteria based on plateness, mobility, and their standard deviations are presented and discussed. The results show that the yield stress of the lithosphere has profound effects on the tectonic convective *** the gradual increase of yield stress, the tectonic mode of mantle convection changes from one to another sequentially through the aforementioned five modes. Additionally, as the Rayleigh number increases, the range of yield stress for the platelike mobile-lid convective mode decreases, and the dimensionless transition stress between different tectonic modes ***, the dimensional transition stress between the non-plate mobile-lid convective mode and plate-like mobile-lid convective mode increases with the increase of Rayleigh number, but decreases between other tectonic modes. Furthermore, we find that the transition stress between different tectonic modes is inversely proportional to the internal heating rate, with the transition stress decreasing as the internal heating rate increases. The fitting analysis of the transition stress between tectonic modes shows that Earth's current plate tectonics correspond to a lithospheric yield stress of 150–250 MPa, which aligns with the strength of serpentinized mantle rock determined by experimental petrography. If the Archean mantle was 300°C warmer than it is today, then the Earth was in an episodic stagnant-lid convective mode. The tectonic evolution of the Earth's surface is closely related to the lithospheric strength and the process of thermal evolution. If the lithospheric strength w

关键词： Tectonic mode of mantle convection Plate-like mobile-lid convection Episodic plate-like mobile-lid convection Episodic stagnant-lid convection Plate tectonics and tectonic evolution of the Earth