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Track-Pattern-Based Characteristics of Extratropical Transitioning Tropical Cyclones in the Western North Pacific

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Advances in Atmospheric Sciences 2024年第6期41卷 1251-1263页

作者： hong huang Dan WU Yuan WANG Zhen WANG Yu LIU College of Meteorology and Oceanography National University of Defense TechnologyChangsha 410000China No.31631 Army of PLA Huizhou 516000China School of Atmospheric Sciences and Key Laboratory of Mesoscale Severe Weather/Ministry of Education Nanjing 210023China No.93721 Army of PLA Shuozhou 038300China

Based on the Regional Specialized Meteorological Center(RSMC)Tokyo-Typhoon Center best-track data and the NCEP-NCAR reanalysis dataset,extratropical transitioning(ET)tropical cyclones(ETCs)over the western North Pacific(WNP)during 1951–2021 are classified into six clusters using the fuzzy c-means clustering method(FCM)according to their track *** characteristics of the six hard-clustered ETCs with the highest membership coefficient are *** tropical cyclones(TCs)that were assigned to clusters C2,C5,and C6 made landfall over eastern Asian countries,which severely threatened these *** landfalling TCs,93.2%completed their ET after landfall,whereas 39.8%of ETCs completed their transition within one *** frequency of ETCs over the WNP has decreased in the past four decades,wherein cluster C5 demonstrated a significant decrease on both interannual and interdecadal timescales with the expansion and intensification of the western Pacific subtropical high(WPSH).This large-scale circulation pattern is favorable for C2 and causes it to become the dominant track pattern,owning to it containing the largest number of intensifying ETCs among the six clusters,a number that has increased insignificantly over the past four *** surface roughness variation and three-dimensional background circulation led to C5 containing the maximum number of landfalling TCs and a minimum number of intensifying *** results will facilitate a better understanding of the spatiotemporal distributions of ET events and associated environment background fields,which will benefit the effective monitoring of these events over the WNP.

关键词： Western North Pacific tropical cyclone extratropical transition fuzzy c-means clustering method

Fecal microbiota transplantation for irritable bowel syndrome:Current evidence and perspectives

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World Journal of Gastroenterology 2024年第16期30卷 2179-2183页

作者： Cong Dai Yu-hong huang Min Jiang Department of Gastroenterology First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina

In this editorial we comment on the article published in the recent issue of the World journal of *** focus specifically on the mechanisms underlying the effects of fecal microbiota transplantation(FMT)for irritable bowel syndrome(IBS),the factors which affect the outcomes of FMT in IBS patients,and *** has emerged as a efficacious intervention for clostridium difficile infection and holds promise as a therapeutic modality for *** utilization of FMT in the treatment of IBS has undergone scrutiny in numerous randomized controlled trials,yielding divergent *** current frontier in this field seeks to elucidate these variations,underscore the existing knowledge gaps that necessitate exploration,and provide a guideline for successful FMT implementation in IBS *** the same time,the application of FMT as a treatment for IBS confronts several challenges.

关键词： Fecal microbiota transplantation Irritable bowel syndrome Microbiota Randomized controlled trial Meta-analysis

Media Power Measuring via Emotional Contagion

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Journal of Social Computing 2024年第1期5卷 15-35页

作者： Xue Lin hong huang Zongya Li Hai Jin National Engineering Research Center for Big Data Technology and System Services Computing Technology and System LabCluster and Grid Computing LabSchool of Computer Science and TechnologyHuazhong University of Science and TechnologyWuhan 430074China School of Journalism Huazhong University of Science and TechnologyWuhan 430074China

Media power,the impact that media have on public opinion and perspectives,plays a significant role in maintaining internal stability,exerting external influence,and shaping international dynamics for nations/***,prior research has primarily concentrated on news content and reporting time,resulting in limitations in evaluating media *** more accurately assess media power,we use news content,news reporting time,and news emotion simultaneously to explore the emotional contagion between *** use emotional contagion to measure the mutual influence between media and regard the media with greater impact as having stronger media *** propose a framework called Measuring Media Power via Emotional Contagion(MMPEC)to capture emotional contagion among media,enabling a more accurate assessment of media power at the media and national/regional *** also interprets experimental results through correlation and causality analyses,ensuring *** analyses confirm the higher accuracy of MMPEC compared to other baseline models,as demonstrated in the context of COVID-19-related news,yielding compelling and interesting insights.

关键词： explainability media power emotional contagion

A Gaussian Noise-Based Algorithm for Enhancing Backdoor Attacks

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Computers, Materials & Continua 2024年第7期80卷 361-387页

作者： hong huang Yunfei Wang Guotao Yuan Xin Li School of Computer Science and Engineering Sichuan University of Science&EngineeringYibin644000China

Deep Neural Networks(DNNs)are integral to various aspects of modern life,enhancing work ***-less,their susceptibility to diverse attack methods,including backdoor attacks,raises security *** aim to investigate backdoor attack methods for image categorization tasks,to promote the development of DNN towards higher *** on backdoor attacks currently faces significant challenges due to the distinct and abnormal data patterns of malicious samples,and the meticulous data screening by developers,hindering practical attack *** overcome these challenges,this study proposes a Gaussian Noise-Targeted Universal Adversarial Perturbation(GN-TUAP)*** approach restricts the direction of perturbations and normalizes abnormal pixel values,ensuring that perturbations progress as much as possible in a direction perpendicular to the decision hyperplane in linear *** limits anomalies within the perturbations improves their visual stealthiness,and makes them more challenging for defense methods to *** verify the effectiveness,stealthiness,and robustness of GN-TUAP,we proposed a comprehensive threat *** on this model,extensive experiments were conducted using the CIFAR-10,CIFAR-100,GTSRB,and MNIST datasets,comparing our method with existing state-of-the-art attack *** also tested our perturbation triggers using various defense methods and further experimented on the robustness of the triggers against noise filtering *** experimental outcomes demonstrate that backdoor attacks leveraging perturbations generated via our algorithm exhibit cross-model attack effectiveness and superior ***,they possess robust anti-detection capabilities and maintain commendable performance when subjected to noise-filtering methods.

关键词： Image classification model backdoor attack gaussian distribution Artificial Intelligence(AI)security

BSTFNet:An Encrypted Malicious Traffic Classification Method Integrating Global Semantic and Spatiotemporal Features

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Computers, Materials & Continua 2024年第3期78卷 3929-3951页

作者： hong huang Xingxing Zhang Ye Lu Ze Li Shaohua Zhou School of Computer Science and Engineering Sichuan University of Science&EngineeringYibin644002China School of Mathematics and Statistics Sichuan University of Science&EngineeringYibin644002China

While encryption technology safeguards the security of network communications,malicious traffic also uses encryption protocols to obscure its malicious *** address the issues of traditional machine learning methods relying on expert experience and the insufficient representation capabilities of existing deep learning methods for encrypted malicious traffic,we propose an encrypted malicious traffic classification method that integrates global semantic features with local spatiotemporal features,called BERT-based Spatio-Temporal Features Network(BSTFNet).At the packet-level granularity,the model captures the global semantic features of packets through the attention mechanism of the Bidirectional Encoder Representations from Transformers(BERT)*** the byte-level granularity,we initially employ the Bidirectional Gated Recurrent Unit(BiGRU)model to extract temporal features from bytes,followed by the utilization of the Text Convolutional Neural Network(TextCNN)model with multi-sized convolution kernels to extract local multi-receptive field spatial *** fusion of features from both granularities serves as the ultimate multidimensional representation of malicious *** approach achieves accuracy and F1-score of 99.39%and 99.40%,respectively,on the publicly available USTC-TFC2016 dataset,and effectively reduces sample confusion within the Neris and Virut *** experimental results demonstrate that our method has outstanding representation and classification capabilities for encrypted malicious traffic.

关键词： Encrypted malicious traffic classification bidirectional encoder representations from transformers text convolutional neural network bidirectional gated recurrent unit

Causal role of immune cells in obstructive sleep apnea hypopnea syndrome:Mendelian randomization study

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World Journal of Clinical Cases 2024年第7期12卷 1227-1234页

作者： huang-hong Zhao Zhen Ma Dong-Sheng Guan Department of Encephalopathy Henan Provincial Hospital of Traditional Chinese MedicineZhengzhou 450000Henan ProvinceChina Department of Personnel The First Affiliated Hospital of Henan University of Traditional Chinese MedicineZhengzhou 450000Henan ProvinceChina Department of Neurology Henan Provincial Hospital of Traditional Chinese MedicineZhengzhou 450000Henan ProvinceChina

BACKGROUND Despite being one of the most prevalent sleep disorders,obstructive sleep apnea hypoventilation syndrome(OSAHS)has limited information on its immunologic *** immunological underpinnings of certain major psychiatric diseases have been uncovered in recent years thanks to the extensive use of genome-wide association studies(GWAS)and genotyping techniques using highdensity genetic markers(e.g.,SNP or CNVs).But this tactic hasn't yet been applied to *** a Mendelian randomization analysis,we analyzed the causal link between immune cells and the illness in order to comprehend the immunological bases of *** To investigate the immune cells'association with OSAHS via genetic methods,guiding future clinical *** A comprehensive two-sample mendelian randomization study was conducted to investigate the causal relationship between immune cell characteristics and *** statistics for each immune cell feature were obtained from the GWAS *** on 731 immune cell properties,such as morphologic parameters,median fluorescence intensity,absolute cellular,and relative cellular,was compiled using publicly available genetic *** results'robustness,heterogeneity,and horizontal pleiotropy were confirmed using extensive sensitivity *** Following false discovery rate(FDR)correction,no statistically significant effect of OSAHS on immunophenotypes was ***,two lymphocyte subsets were found to have a significant association with the risk of OSAHS:Basophil%CD33dim HLA DR-CD66b-(OR=1.03,95%CI=1.01-1.03,P<0.001);CD38 on IgD+CD24-B cell(OR=1.04,95%CI=1.02-1.04,P=0.019).CONCLUSION This study shows a strong link between immune cells and OSAHS through a gene approach,thus offering direction for potential future medical research.

关键词： Obstructive sleep apnea hypopnea syndrome Immunity Causal inference MR analysis Sensitivity

Development and validation of a new prognostic model for patients with acute-on-chronic liver failure in intensive care unit

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World Journal of Gastroenterology 2024年第20期30卷 2657-2676页

作者： Zong-Yi Zhu Xiu-hong huang Hui-Qing Jiang Li Liu Department of Gastroenterology The Second Hospital of Hebei Medical UniversityShijiazhuang 050000Hebei ProvinceChina Department of Gastroenterology Weixian People's HospitalXingtai 054700Hebei ProvinceChina

BACKGROUND Cirrhotic patients with acute-on-chronic liver failure(ACLF)in the intensive care unit(ICU)have a poor but variable *** prognosis evaluation can guide the rational management of patients with ***,existing prognostic scores for ACLF in the ICU environment lack sufficient *** To develop a new prognostic model for patients with ACLF in *** Data from 938 ACLF patients in the Medical Information Mart for Intensive Care(MIMIC)database were used to develop a new prognostic model(MIMIC ACLF)for ***,calibration and clinical utility of MIMIC ACLF were assessed by area under receiver operating characteristic curve(AUROC),calibration curve and decision curve analysis(DCA),*** ACLF was then externally validated in a multiple-center cohort,the Electronic Intensive Care Collaborative Research Database and a single-center cohort from the Second Hospital of Hebei Medical University in *** The MIMIC ACLF score was determined using nine variables:ln(age)×2.2+ln(white blood cell count)×0.22-ln(mean arterial pressure)×2.7+respiratory failure×0.6+renal failure×0.51+cerebral failure×0.31+ln(total bilirubin)×0.44+ln(internationalized normal ratio)×0.59+ln(serum potassium)×*** MIMIC cohort,the AUROC(0.81/0.79)for MIMIC ACLF for 28/90-day ACLF mortality were significantly greater than those of Chronic Liver Failure Consortium ACLF(0.76/0.74),Model for End-stage Liver Disease(MELD;0.73/0.71)and MELD-Na(0.72/0.70)(all P<0.001).The consistency between actual and predicted 28/90-day survival rates of patients according to MIMIC ACLF score was excellent and superior to that of existing *** net benefit of MIMIC ACLF was greater than that achieved using existing scores within the 50%threshold *** superior predictive accuracy and clinical utility of MIMIC ACLF were validated in the external *** We developed and validated a new prognostic model with satisfactory accuracy

关键词： Acute-on-chronic liver failure Cirrhosis Risk stratification Prognosis Model Scores

Integrated multi-omics analysis reveals liver metabolic reprogramming by fish iridovirus and antiviral function of alpha-linolenic acid

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Zoological Research 2024年第3期45卷 520-534页

作者： Lin Liu Ya Zhang Meng-Di Yuan Dong-Miao Xiao Wei-Hua Xu Qi Zheng Qi-Wei Qin You-Hua huang Xiao-hong huang College of Marine Sciences South China Agricultural UniversityGuangdong Laboratory for Lingnan Modern AgricultureGuangzhouGuangdong 510642China Nansha-South China Agricultural University Fishery Research Institute GuangzhouGuangdong 511464China Southern Marine Science and Engineering Guangdong Laboratory ZhuhaiGuangdong 519082China

Iridovirus poses a substantial threat to global aquaculture due to its high mortality rate;however,the molecular mechanisms underpinning its pathogenesis are not well ***,a multi-omics approach was applied to groupers infected with Singapore grouper iridovirus(SGIV),focusing on the roles of key *** showed that SGIV induced obvious histopathological damage and changes in metabolic enzymes within the ***,SGIV significantly reduced the contents of lipid droplets,triglycerides,cholesterol,and *** analysis indicated that the altered metabolites were enriched in 19 pathways,with a notable down-regulation of lipid metabolites such as glycerophosphates and alpha-linolenic acid(ALA),consistent with disturbed lipid homeostasis in the *** of transcriptomic and metabolomic data revealed that the top enriched pathways were related to cell growth and death and nucleotide,carbohydrate,amino acid,and lipid metabolism,supporting the conclusion that SGIV infection induced liver metabolic *** integrative transcriptomic and proteomic analysis indicated that SGIV infection activated crucial molecular events in a phagosome-immune depression-metabolism dysregulation-necrosis signaling *** note,integrative multi-omics analysis demonstrated the consumption of ALA and linoleic acid(LA)metabolites,and the accumulation of L-glutamic acid(GA),accompanied by alterations in immune,inflammation,and cell death-related *** experimental data showed that ALA,but not GA,suppressed SGIV replication by activating antioxidant and anti-inflammatory responses in the ***,these findings provide a comprehensive resource for understanding host response dynamics during fish iridovirus infection and highlight the antiviral potential of ALA in the prevention and treatment of iridoviral diseases.

关键词： Iridovirus Liver damage Metabolic reprogramming SGIV Alpha-linolenic acid Antiinflammatory

Inhibition of the NF-κB Signaling Pathway Improves Cigarette Mainstream Smoke-Induced Lung Injury and Gut Microbiota Disturbance

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Biomedical and Environmental Sciences 2024年第6期37卷 676-681页

作者： hong huang Shengjie Li Lifang Zeng Yan Zhang Ying Chen Yanbing Ma Jing Wei Changwei Zou Tingtao Chen School of Resources and Environment Nanchang UniversityNanchang 330031JiangxiChina National Engineering Research Center for Bioengineering Drugs and the Technologies Institute of Translational MedicineJiangxi Medical CollegeNanchang UniversityNanchang 330031JiangxiChina School of Pharmacy Jiangxi Medical CollegeNanchang UniversityNanchang 330006JiangxiChina

Currently,cigarette smoke(CS)remains a major contributor to disease morbidity and *** can be divided into cigarette mainstream smoke(CMS)and side-stream smoke,depending on where it is produced by burning tobacco^([1]).CMS is inhaled by smokers from the filter end during cigarette combustion and is strongly associated with the development of several diseases^([2-4]).

关键词： smoke CMS cigarette