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Journal of Systems Science & Complexity 2014年第2期27卷 276-288页

作者： sun Yudong SHI Yimin GU xin Department of Applied Mathematics Northwestern Polytechnical University Department of Methodology and Statistics Utrecht University

This paper studies the nonlinear variational inequality with integro-differential term arising from valuation of American style double barrier option. First, the authors use the penalty method to transform the variational inequality into a nonlinear parabolic initial boundary problem(i.e., penalty problem). Second, the existence and uniqueness of solution to the penalty problem are proved by using the Scheafer fixed point theory. Third, the authors prove the existence of variational inequality' solution by showing the fact that the penalized PDE converges to the variational inequality. The uniqueness of solution to the variational inequality is also proved by contradiction.

关键词： American style barrier option existence integro-differential uniqueness variational inequality.

EFFECTIVE SPECIFIC HEATS OF MULTI-PHASE THERMOELASTIC COMPOSITES

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Acta Mechanica Solida Sinica 2012年第3期25卷 262-276页

作者： Yongqiang Chen Ruchao huang Zhuping huan Lizhi sun Department of Mechanics and Engineering Science College of EngineeringPeking UniversityBeijing 100871China Department of Civil and Environmental Engineering University of CaliforniaIrvineCA 92697-2175USA

This paper studies the effective properties of multi-phase thermoelastic composites. Based on the Helmholtz free energy and the Gibbs free energy of individual phases, the effective elastic tensor, thermal-expansion tensor, and specific heats of the multi-phase composites are derived by means of the volume average of free-energies of these phases. Particular emphasis is placed on the derivation of new analytical expressions of effective specific heats at constant-strain and constant-stress situations, in which a modified Eshelby＇s micromechanics theory is developed and the interaction between inclusions is considered. As an illustrative example, the analytical expression of the effective specific heat for a three-phase thermoelastic composite is presented.

关键词： composite materials effective specific heat micromechanics free energy thermoe-lasticity

Hypoglycemic polysaccharides from Auricularia auricula and Auricularia polytricha inhibit oxidative stress,NF-κB signaling and proinflammatory cytokine production in streptozotocin-induced diabetic mice

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Food Science and Human Wellness 2021年第1期10卷 87-93页

作者： huan Xiang Dongxiao sun-Waterhouse Chun Cui School of Food Science and Engineering South China University of TechnologyGuangzhou510640GuangdongChina Guangdong Weiwei Biotechnology Co. LTDGuangzhou510640GuangdongChina School of Chemical Sciences The University of AucklandPrivate Bag 92019AucklandNew Zealand

Auricularia auricula(AA)and Auricularia polytricha(AP)are popular edible *** study successfully produced hypoglycemic polysaccharides from un-smashed or smashing and sieving(through a 10-mesh sieve)AA and AP(termed as AAP/AAP-10 and APP/APP-10)via scalable processes(water extraction,ethanolic precipitation and deproteinization).This is the first report to compare the effectiveness of AAP and APP in combating streptozotocin-induced oxidative stress and diabetes-related changes in mice(body weight,fasting blood glucose,serum insulin,proinflammatory mediator and cytokines,oxidative stress-related products,antioxidant enzymes).APP and AAP with different molecular weights and monosaccharide molar ratios could be therapeutic options for diabetes with a low dose(100 mg/kg/day)likely working *** the same dose,APP generally performed more effective than AAP,and AAP-10/APP-10 seemed slightly more beneficial than AAP/*** mechanism underlying these antidiabetic functions might involve the NF-κB and associated signalling *** is cheaper than AA,thereby representing a favorable source of functional polysaccharides.

关键词： Polysaccharides Auricularia auricula Auricularia polytricha Hypoglycemic effect Oxidative stress

Evaluation of water management on arsenic methylation and volatilization in arsenic-contaminated soils strengthened by bioaugmentation and biostimulation

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Journal of Environmental Sciences 2024年第3期137卷 515-526页

作者： Peng Chen Yi Liu Guo-xin sun State Key Laboratory of Urban and Regional Ecology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China Key Laboratory of Aquatic Botany and Watershed Ecology Wuhan Botanical GardenChinese Academy of SciencesWuhan 430074China University of Chinese Academy of Sciences Beijing 100049China

Arsenic(As) fate in paddy fields has been one of the most significant current issues due to the strong As accumulation potential of rice plants under fooded conditions. However,no attempt was done to explore As methylation and volatilization under non-fooded conditions. Herein, we investigated the effects of water management on As methylation and volatilization in three arsenic-contaminated soils enhanced by biostimulation with strawderived organic matter and bioaugmentation with genetic engineered Pseudomonas putida KT2440(GE P. putida). Under fooded conditions, the application of biochar(BC), rice straw(RS)and their combination(BC+RS) increased total As in porewater. However, these effects were greatly attenuated under non-fooded conditions. Compared with RS amendment alone, the combination of GE P. putida and RS further promoted the As methylation and volatilization,and the promotion percentage under non-fooded conditions were significantly higher than that under fooded conditions. The combined GE P. putida and RS showed the highest efficiency in As methylation(88 μg/L) and volatilization(415.4 μg/(kg·year)) in the non-fooded soil with moderate As contamination. Finally, stepwise multiple linear regression analysis presented that methylated As, DOC and p H in porewater were the most important factors contributing to As volatilization. Overall, our findings suggest that combination of bioaugmentation with GE P. putida and biostimulation with RS/BC+RS is a potential strategy for bioremediation of arsenic-contaminated soils by enhancing As methylation and volatilization under non-fooded conditions.

关键词： Arsenic methylation Arsenic volatilization Water management Straw incorporation Bioaugmentation

Semantic segmentation-assisted instance feature fusion for multi-level 3D part instance segmentation

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Computational Visual Media 2023年第4期9卷 699-715页

作者： Chun-Yu sun xin Tong Yang Liu Institute for Advanced Study Tsinghua UniversityBeijing 100084China Microsoft Research Asia Beijing 100080China

Recognizing 3D part instances from a 3D point cloud is crucial for 3D structure and scene *** learning-based approaches use semantic segmentation and instance center prediction as training tasks and fail to further exploit the inherent relationship between shape semantics and part *** this paper,we present a new method for 3D part instance *** method exploits semantic segmentation to fuse nonlocal instance features,such as center prediction,and further enhances the fusion scheme in a multi-and cross-level *** also propose a semantic region center prediction task to train and leverage the prediction results to improve the clustering of instance *** method outperforms existing methods with a large-margin improvement in the PartNet *** also demonstrate that our feature fusion scheme can be applied to other existing methods to improve their performance in indoor scene instance segmentation tasks.

关键词： 3D part instance segmentation feature fusion 3D deep learning

Analysis of pressure response at an observation well against pressure build-up by early stage of CO_(2)geological storage project

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第2期16卷 470-482页

作者： Qiang sun Kyuro Sasaki Qinxi Dong Zhenni Ye Hui Wang huan sun School of Civil Engineering and Architecture Hainan UniversityHaikou570228China Faculty of Engineering Kyushu University744 MotookaNishi-kuFukuoka819-0385Japan Key Laboratory of Equipment Safety and Intelligent Technology for Guangzhou Rail Transit System Guangzhou510430China

To ensure a safe and stable CO_(2)storage,pressure responses at an observation well are expected to be an important and useful field monitoring item to estimate the CO_(2)storage behaviors and the aquifer parameters during and after injecting CO_(2),because it can detect whether the injected CO_(2)leaks to the ground surface or the bottom of the *** this study,pressure responses were simulated to present design factors such as well location and pressure transmitter of the observation *** simulations on the pressure response and the time-delay from pressure build-up after CO_(2)injection were conducted by considering aquifer parameters and distance from the CO_(2)injection well to an observation *** measurement resolution of a pressure transmitter installed in the observation well was presented based on numerical simulation results of the pressure response against pressure build-up at the injection well and CO_(2)plume front ***,the pressure response at an observation well was estimated by comparing the numerical simulation results with the curve of CO_(2)saturation and relative *** was also suggested that the analytical solution can be used for the analysis of the pressure response tendency using pressure build-up and dimensionless parameters of hydraulic ***,a criterion was established for selecting a pressure transducer installed at an observation well to monitor the pressure responses with sufficient accuracy and resolution,considering the distance from the injection well and the pressure build-up at the injection well,for future carbon capture and storage(CCS)projects.

关键词： CO_(2)storage Saline aquifer Observation well Pressure response CO_(2)saturation

Fracture Mechanism of the Formation with a Natural Flaw Under a Single-Tooth Cutting

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Acta Mechanica Solida Sinica 2020年第5期33卷 719-730页

作者： Siqi Li Wei Li Tie Yan Fuqing Bi huan Zhao xin Ling Institute of Petroleum Engineering Northeast Petroleum UniversityDaqing163318HeilongjiangChina The Fifth Oil Production Plant of Daqing Oilfield Daqing163513HeilongjiangChina

The process of a single-tooth cutting formation is taken as the representative to analyze the fracture mechanism of the formation with natural flaws under the PDC drill *** modeling of the stress field distribution of the formation under a single tooth is proposed ***,the modeling of the stress intensity factor K,T-stress and the initiation angleθof the flaw under two far-field compressive loads in two cases are presented based on the mode-II ***,the results of theoretical calculations and simulations are given and *** on the analysis undertaken,it can be concluded that the confinement ratioλapplying on the flaw changes nonlinearly with the variation inα+φ.The relationship between the dimensionless ratioβx/βy of T-stress and the rotational polar angleφis a parabola with an upward *** the direction of the cutting force is consistent with the flaw,the stress intensity factor K and the initiation angleθat the tip of the flaw reach the *** addition,the angle between the cutting force and the flaw weakens the T-stress and inhibits the crack initiation and propagation of the *** results of numerical simulations show good agreement with theoretical calculations.

关键词： Single-tooth cutting Stress field Stress intensity factor Initiation angle Extended finite element

Blinking adaptation for synchronizing a mobile agent network

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Journal of Zhejiang University-Science C(Computers and Electronics) 2011年第8期12卷 658-666页

作者： huan SHI Hua-ping DAI You-xian sun State Key Laboratory of Industrial Control Technology Zhejiang University Hangzhou 310027 China

We investigate the issue of synchronizing a blinking coupling mobile agent network through a blinking adaptation strategy,where each agent with blinking wave emission behavior not only adjusts its blinking period according to the local property of its neighbors,but also coordinates its blinking phase with those of neighboring *** leading the agents to blink orderly with a blinking period commensurate with the characteristic time of the dynamical oscillator,the presented blinking adaptation strategy works effectively in guaranteeing the synchronous motion of the considered network when the power density is *** addition,the influence of the controlling parameter and moving velocity on network evolution is studied by assessing the convergence time.

关键词： Mobile agents Blinking adaptation Coupled-oscillator networks Synchronization

Factor graph aided multiple hypothesis tracking

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Science China(Information Sciences) 2013年第10期56卷 284-289页

作者： WANG huan sun JinPing LU SongTao WEI ShaoMing School of Electronic and Information Engineering Beihang University Department of Electrical and Computer Engineering Iowa State University

Since closely moving targets exist extensively in the ground moving target tracking,the uncertainty of data association greatly increases making the measurement-to-track association more ***,traditional multiple hypothesis tracking(MHT)has high false tracking rate and track *** paper frst investigates the measurement based factor graph in data association,and gives the corresponding message passing ***,a factor graph aided multiple hypothesis tracking(FGA-MHT)method is proposed,which introduces factor graph based m-best hypothesis producing technique and exploits factor graph based probability refnement algorithm to reduce the uncertainty of measurement-to-track *** results demonstrate that FGA-MHT reduces times of track swap and increases the correct data association rate in closely moving target tracking.

关键词： multiple hypothesis tracking(MHT) data association factor graph message passing algorithm sum-product algorithm factor graph aided multiple hypothesis tracking(FGA-MHT

Nanomedicine-boosting icaritin-based immunotherapy of advanced hepatocellular carcinoma

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Military Medical Research 2023年第3期10卷 403-414页

作者： Yi Lu Yue Gao huan Yang Yong Hu xin Li Department of Polymeric Materials School of Materials Science and EngineeringTongji UniversityShanghai 201804China Institute of Biotechnology RWTH Aachen University52074 AachenGermany DWI-Leibniz-Institute for Interactive Materials e.V. 52056 AachenGermany College of Chemistry Chemical Engineering and BiotechnologyDonghua UniversityShanghai 201620China School of Pharmacy Jiangsu UniversityZhenjiang 212013JiangsuChina Institute of Technical and Macromolecular Chemistry RWTH Aachen University52074 AachenGermany

Traditional treatments for advanced hepatocellular carcinoma(HCC),such as surgical resection,transplantation,radiofrequency ablation,and chemotherapy are unsatisfactory,and therefore the exploration of powerful therapeutic strategies is urgently *** has emerged as a promising strategy for advanced HCC treatment due to its minimal side effects and long-lasting therapeutic memory *** studies have demonstrated that icaritin could serve as an immunomodulator for effective immunotherapy of advanced ***,in 2022,icaritin soft capsules were approved by the National Medical Products Administration(NMPA)of China for the immunotherapy of advanced ***,the therapeutic efficacy of icaritin in clinical practice is impaired by its poor bioavailability and unfavorable in vivo delivery ***,functionalized drug delivery systems including stimuli-responsive nanocarriers,cell membrane-coated nanocarriers,and living cell-nanocarrier systems have been designed to overcome the shortcomings of drugs,including the low bioavailability and limited delivery efficiency as well as side *** together,the development of icaritin-based nanomedicines is expected to further improve the immunotherapy of advanced ***,we compared the different preparation methods for icaritin,interpreted the HCC immune microenvironment and the mechanisms underlying icaritin for treatment of advanced HCC,and discussed both the design of icaritin-based nanomedicines with high icaritin loading and the latest progress in icaritinbased nanomedicines for advanced HCC ***,the prospects to promote further clinical translation of icaritin-based nanomedicines for the immunotherapy of advanced HCC were proposed.

关键词： Icaritin Nanomedicine Advanced hepatocellular carcinoma Immunotherapy Clinical translation